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the official  training programme of the Surviving Sepsis Campaign
Objectives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Is sepsis important? ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],39.8%
Lung 1 Colon 2 Breast 3 Sepsis 4 cancers Annual  UK mortality  (2003),  thousands 1,2,3  www.statistics.gov.uk,,  4 Intensive Care National Audit Research Centre (2005) A U.K. Perspective
Identifying the Septic Patient
ACCP/SCCM Consensus Definitions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Bone RC et al.  Chest.  1992;101:1644-55 . Identifying sepsis now known as SSI
Step 1: What is SSI? A systemic response to a nonspecific insult Infection, trauma, surgery, massive transfusion, etc Defined as   2 of the following : Temperature  >38.3 or <36  0 C Heart rate >90 min-1 Respiratory rate  >20 min-1 White cells  <4 or >12 Acutely altered mental state Hyperglycaemia (BM>6.6) in absence of DM Identifying sepsis SIRS SEVERE SEPSIS
Step 2: What counts as an infection? Pneumonia Urinary Tract infection Meningitis Endocarditis Device related Central line Cannula Abdominal Pain Diarrhoea Distension Urgent laparotomy Soft tissue/ musculoskeletal Cellulitis Septic arthritis Fasciitis Wound infection Identifying sepsis
Step 3: what is Sepsis? ,[object Object],Identifying sepsis
Step 4: what is Severe Sepsis? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Identifying sepsis
What is shock? ,[object Object],Identifying sepsis ,[object Object],[object Object],[object Object],[object Object],[object Object],Septic Shock Shock secondary to systemic inflammatory response to a new infection
Putting this together ,[object Object],[object Object]
Are any 2 of the following present and new to the patient? Temperature >38.3 or <36  0 C Heart rate >90 min -1 Respiratory rate >20 min -1 White cells <4 or >12 g/L Acutely altered mental status Hyperglycaemia (glucose>6.6mmol/L) (unless diabetic) Screening Tool Severe Sepsis Screening Tool If yes,  patient has SSI
Is the history suggestive of a new infection? Pneumonia UTI Abdo pain/ diarrhoea/ distension/ urgent laparotomy Meningitis Cellulitis/ septic arthritis/ fasciitis/ wound infection Endocarditis Catheter (incl central venous) infection Screening Tool If yes,  patient has SSI If yes,  patient has SEPSIS
Are any of the following present and new to the patient? Blood pressure systolic <90 or mean <65 mmHg  New or increased O2 requirement to maintain SpO2>90% Creatinine >177 mmol/l or UO <0.5 ml/kg/hr for 2 hrs Bilirubin >34 mmol/l Platelets <100 Lactate >2 mmol/l Coagulopathy: INR>1.5 or aPTT>60s Screening Tool If yes,  patient has SEPSIS The patient has SEVERE SEPSIS Start Severe Sepsis Care Pathway
Septic Shock ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
The Surviving Sepsis Campaign Resuscitation Bundle ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],…  within 6 hours of onset!
What you can do ,[object Object],[object Object],Sepsis Six • Oxygen • Blood Cultures • Antibiotics • Fluids • Lactate &  Hb • Insert Catheter & monitor urine output Sepsis Six • Oxygen • Blood Cultures • Antibiotics • Fluids • Lactate &  Hb • Insert Catheter & monitor urine output
 
At risk groups? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Why are patients high risk? ,[object Object],[object Object],[object Object],[object Object]
Summary ,[object Object],[object Object],[object Object],[object Object],[object Object]
the official  training programme of the Surviving Sepsis Campaign Questions

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Surviving Sepsis

  • 1. the official training programme of the Surviving Sepsis Campaign
  • 2.
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  • 5. Lung 1 Colon 2 Breast 3 Sepsis 4 cancers Annual UK mortality (2003), thousands 1,2,3 www.statistics.gov.uk,, 4 Intensive Care National Audit Research Centre (2005) A U.K. Perspective
  • 7.
  • 8. Step 1: What is SSI? A systemic response to a nonspecific insult Infection, trauma, surgery, massive transfusion, etc Defined as  2 of the following : Temperature >38.3 or <36 0 C Heart rate >90 min-1 Respiratory rate >20 min-1 White cells <4 or >12 Acutely altered mental state Hyperglycaemia (BM>6.6) in absence of DM Identifying sepsis SIRS SEVERE SEPSIS
  • 9. Step 2: What counts as an infection? Pneumonia Urinary Tract infection Meningitis Endocarditis Device related Central line Cannula Abdominal Pain Diarrhoea Distension Urgent laparotomy Soft tissue/ musculoskeletal Cellulitis Septic arthritis Fasciitis Wound infection Identifying sepsis
  • 10.
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  • 14. Are any 2 of the following present and new to the patient? Temperature >38.3 or <36 0 C Heart rate >90 min -1 Respiratory rate >20 min -1 White cells <4 or >12 g/L Acutely altered mental status Hyperglycaemia (glucose>6.6mmol/L) (unless diabetic) Screening Tool Severe Sepsis Screening Tool If yes, patient has SSI
  • 15. Is the history suggestive of a new infection? Pneumonia UTI Abdo pain/ diarrhoea/ distension/ urgent laparotomy Meningitis Cellulitis/ septic arthritis/ fasciitis/ wound infection Endocarditis Catheter (incl central venous) infection Screening Tool If yes, patient has SSI If yes, patient has SEPSIS
  • 16. Are any of the following present and new to the patient? Blood pressure systolic <90 or mean <65 mmHg New or increased O2 requirement to maintain SpO2>90% Creatinine >177 mmol/l or UO <0.5 ml/kg/hr for 2 hrs Bilirubin >34 mmol/l Platelets <100 Lactate >2 mmol/l Coagulopathy: INR>1.5 or aPTT>60s Screening Tool If yes, patient has SEPSIS The patient has SEVERE SEPSIS Start Severe Sepsis Care Pathway
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  • 25. the official training programme of the Surviving Sepsis Campaign Questions