2. History
A 32-year old female, married, from
Zefta presented to ER with:
◦ Shortness of breath
◦ Bilateral leg swelling
◦ Oliguria
3. History
Present history
The condition started one month ago
by gradual onset and progressive
course of dyspnea on exertion, lower
limbs edema and oliguria.
She was diagnosed to have SLE 1
month prior to presentation.
4. History
Past history
No history of hypertension, diabetes, CKD,
surgery.
History of rheumatic heart disease since
childhood.
Frequent suicidal attempts and antipsychotic
therapy for depression for 9 years
History of 2 abortions.
17. Neurological consultations was done
in view of psychosis and unilateral
weakness and orderd Brain MRI
which revealed:
Multiple small recent infarcts mostly
due to underlying vasculitis
19. After neurological consultationWe
decided to start:
Pulse steroid therapy with
Methylprednisolone 500 mg for
five days under cover of
Imipenem.
Plasma exchange for 5 sessions
(via right IJ vein CVC).
Warfarin 3mg/day.
25. Progress notes:
The patient condition stabilized with
improvement of neurological symptoms
and signs.
CRP: 6
After completion of pulse steroid dose
Prednisone 60 mg/d plus Azathioprine 100
mg/d were initiated.
27. After 1 week during the follow up visit
the patint presented with fever and
chills.
During clinical exam an ejection
systolic murmur (new murmur) was
auscultated at the second intercostal
space in the right upper sternal border
radiating to carotid arteries..
36. The patient was switched to
Linezolid 600 mg PO q12hr for
6 weeks.
37. Progress notes:
The patient condition stabilized and fever
subsided.
CRP: 12
Follow up Echo. After 10 days: Decrease
in size of vegitations to 0.3 cm2.
38. Take home messsage:
Aseptic measures are mandatory during
venous catheter manipulation and during
any invasive procedures in order to
reduce the rate of health care-associated
IE.
Echocardiography and blood cultures are
the cornerstone of diagnosis of IE. TTE
must be performed first, but both TTE
and TEE should ultimately be performed
in the majority of cases of suspected or
definite IE.
Notes de l'éditeur
The patient is not known to be diabetic or hypertensive.