Glossary Of Clinical Trials Terms

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This document provides definitions for over 50 terms related to clinical trials. It begins with definitions for terms like adverse reaction, advocacy and support groups, approved drugs, arm (of a clinical trial), and baseline. It then continues to define important clinical trial concepts in alphabetical order, ending with definitions for randomized trial and quality of life trials.

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Glossary of Clinical Trials Terms (Version 1.0) Compiled by: Mersedeh Arvaneh, Irvine CA USA, Sep 2007 All illustration works: by Mersedeh Arvaneh For a free copy of some of the “Conceptual Artworks”, Please email me at [email_address] Conceptual Artworks are available in Technology series, Clinical Trial series, Quality Control Series, 6 Sigma Series, Project Management Series, Health Care series, Meditation Series, Yoga-Inspired Series and more

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ADVOCACY AND SUPPORT GROUPS ,[object Object]

COMMUNITY-BASED CLINICAL TRIAL (CBCT) ,[object Object]

COMPLEMENTARY AND ALTERNATIVE THERAPY ,[object Object]

CONFIDENTIALITY REGARDING TRIAL PARTICIPANTS ,[object Object]

DATA SAFETY AND MONITORING BOARD (DSMB) ,[object Object]

EXCLUSION/INCLUSION CRITERIA ,[object Object]

FOOD AND DRUG ADMINISTRATION (FDA) ,[object Object]

INCLUSION/EXCLUSION CRITERIA ,[object Object]

INFORMED CONSENT DOCUMENT ,[object Object]

INSTITUTIONAL REVIEW BOARD (IRB) ,[object Object]

INVESTIGATIONAL NEW DRUG ,[object Object]

NEW DRUG APPLICATION (NDA): ,[object Object]

PLACEBO CONTROLLED STUDY ,[object Object]

QUALITY OF LIFE TRIALS (or Supportive Care trials) ,[object Object]

RECRUITMENT STATUS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

STATISTICAL SIGNIFICANCE ,[object Object]

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In this lecture on circulatory shock, Dr. Faiza, an Assistant Professor of Physiology, delves into the profound implications of inadequate blood flow throughout the body, leading to tissue damage. The session begins by defining circulatory shock and elucidating its physiological causes, including decreased cardiac output, diminished blood volume, decreased vascular tone, obstruction to blood flow, excess metabolic rate, and abnormal perfusion patterns. Dr. Faiza categorizes shock into various types, such as cardiogenic shock, hypovolemic shock, neurogenic shock, obstructive shock, anaphylactic shock, and septic shock, and explores the pathophysiological basis of each. Furthermore, the lecture examines the stages of shock, from the non-progressive phase where compensatory mechanisms aim for full recovery to the progressive phase where shock worsens steadily without intervention, potentially leading to irreversible damage. Dr. Faiza discusses therapeutic interventions for shock, including replacement therapy, blood and plasma transfusion, sympathomimetic drugs, and other adjunctive treatments like head-down positioning, oxygen therapy, and glucocorticoids.

Circulatory Shock, types and stages, compensatory mechanisms

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Circulatory Shock, types and stages, compensatory mechanisms

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