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COPDWorkgroup
Personalized Care for the COPD Patient
January 14th, 2019
Agenda
 Introductions
 Data and Literature Review
 Discussion
 Wrap Up
Data and
Literature
Review
What is
precision
medicine?
 The right treatment, for the right patient, at the right time.
 A form of medicine that uses information about a person’s genes,
proteins, and environment to prevent, diagnose, and treat
disease.
 Tailoring of medical treatment to the specific characteristics of
each patient
Data and
Personalized
Medicine
 An increase in biological data and relevant medical information
will be seen with personalized medicine
 We have the ability to analyze these data sets and to extract all of
the useful information
COPD and
Personalized
Medicine
 Refers to a label-free, precision medicine approach
 Management is based on individual treatable traits and these
treatable traits are summarized into three groups: pulmonary
treatable traits, extra pulmonary treatable traits, and treatable
behavioral lifestyle risk factors.
Personal
Barriers and
Enablers
Pulmonary
Rehabilitation:
Personalized
Management
 Pulmonary rehabilitation: an intervention based on a “thorough”
patient assessment followed by therapies designed to improve
physical and psychological conditions
 Healthcare practitioners push for a patient-tailored approach to
improve outcomes.
 Push our patients/physicians to adhere to this long-term
The Process of
Getting to a
Patient-
Tailored
Approach
Data and
Literature
Conclusion
 Personalized medicine can fundamentally change the ways
therapies are being developed and explore how genetic,
environmental and lifestyle factors interact in our bodies to foster
health or develop disease.
Discussion
Overview
 Share current practices
 Analyze trends
 Brainstorm future practices and barriers
Discussion
 Is your facility using a patient-tailored approach for COPD
management?
 If so, what does this approach entail?
 What is the biggest psychological/behavioral obstacle your facility
faces related to COPD?
 How does your facility manage these obstacles?
 What self management tools are being used in your facility?
 Do patients have access to their own medical record?
NextSteps
 Next COPDWorkgroup:Tuesday, March 3rd from 2-3:30 pm
 Deliverable &Topic:TBD
Resources
 Agusti, A. (2014).The path to personalised medicine in
COPD. Thorax, 69(9), 857–864. https://doi.org/10.1136/thoraxjnl-2014-
205507
 Franssen, F. M.,Alter, P., Bar, N., Benedikter, B. J., Iurato, S., Maier, D.,
Maxheim, M., Roessler, F. K., Spruit, M. A.,Vogelmeier, C. F.,Wouters,
E. F., & Schmeck, B. (2019). <p>Personalized medicine for patients
with COPD: where are we?</p>. International Journal of Chronic
Obstructive Pulmonary Disease, Volume 14, 1465–1484.
https://doi.org/10.2147/copd.s175706
 Leung, J. M., Obeidat, M., Sadatsafavi, M., & Sin, D. D. (2019).
Introduction to precision medicine in COPD. European Respiratory
Journal, 53(4), 1802460. https://doi.org/10.1183/13993003.02460-2018
 Wouters, E. (2020). HighWire Lens: Personalised pulmonary
rehabilitation in COPD. Ersjournals.Com.
https://err.ersjournals.com/lens/errev/27/147/170125#toc
 Ziegelstein, R. (2017). Personomics:The Missing Link in the Evolution
from Precision Medicine to Personalized Medicine. Journal of
Personalized Medicine, 7(4), 11. https://doi.org/10.3390/jpm7040011

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Chronic Obstructive Pulmonary Disease (COPD) Workgroup 01/14/20

  • 1. COPDWorkgroup Personalized Care for the COPD Patient January 14th, 2019
  • 2. Agenda  Introductions  Data and Literature Review  Discussion  Wrap Up
  • 4. What is precision medicine?  The right treatment, for the right patient, at the right time.  A form of medicine that uses information about a person’s genes, proteins, and environment to prevent, diagnose, and treat disease.  Tailoring of medical treatment to the specific characteristics of each patient
  • 5. Data and Personalized Medicine  An increase in biological data and relevant medical information will be seen with personalized medicine  We have the ability to analyze these data sets and to extract all of the useful information
  • 6. COPD and Personalized Medicine  Refers to a label-free, precision medicine approach  Management is based on individual treatable traits and these treatable traits are summarized into three groups: pulmonary treatable traits, extra pulmonary treatable traits, and treatable behavioral lifestyle risk factors.
  • 8. Pulmonary Rehabilitation: Personalized Management  Pulmonary rehabilitation: an intervention based on a “thorough” patient assessment followed by therapies designed to improve physical and psychological conditions  Healthcare practitioners push for a patient-tailored approach to improve outcomes.  Push our patients/physicians to adhere to this long-term
  • 9. The Process of Getting to a Patient- Tailored Approach
  • 10. Data and Literature Conclusion  Personalized medicine can fundamentally change the ways therapies are being developed and explore how genetic, environmental and lifestyle factors interact in our bodies to foster health or develop disease.
  • 11. Discussion Overview  Share current practices  Analyze trends  Brainstorm future practices and barriers
  • 12. Discussion  Is your facility using a patient-tailored approach for COPD management?  If so, what does this approach entail?  What is the biggest psychological/behavioral obstacle your facility faces related to COPD?  How does your facility manage these obstacles?  What self management tools are being used in your facility?  Do patients have access to their own medical record?
  • 13. NextSteps  Next COPDWorkgroup:Tuesday, March 3rd from 2-3:30 pm  Deliverable &Topic:TBD
  • 14. Resources  Agusti, A. (2014).The path to personalised medicine in COPD. Thorax, 69(9), 857–864. https://doi.org/10.1136/thoraxjnl-2014- 205507  Franssen, F. M.,Alter, P., Bar, N., Benedikter, B. J., Iurato, S., Maier, D., Maxheim, M., Roessler, F. K., Spruit, M. A.,Vogelmeier, C. F.,Wouters, E. F., & Schmeck, B. (2019). <p>Personalized medicine for patients with COPD: where are we?</p>. International Journal of Chronic Obstructive Pulmonary Disease, Volume 14, 1465–1484. https://doi.org/10.2147/copd.s175706  Leung, J. M., Obeidat, M., Sadatsafavi, M., & Sin, D. D. (2019). Introduction to precision medicine in COPD. European Respiratory Journal, 53(4), 1802460. https://doi.org/10.1183/13993003.02460-2018  Wouters, E. (2020). HighWire Lens: Personalised pulmonary rehabilitation in COPD. Ersjournals.Com. https://err.ersjournals.com/lens/errev/27/147/170125#toc  Ziegelstein, R. (2017). Personomics:The Missing Link in the Evolution from Precision Medicine to Personalized Medicine. Journal of Personalized Medicine, 7(4), 11. https://doi.org/10.3390/jpm7040011