2. index
there is no elevators to success,
you have to take the stairs, and always
be Bio-philic !!!
Subject Page
Vitamins 1
Enzymes 4
Nucleic acid 6
Genetics 8
Carbohydrates 10
Lipids 15
Proteins 17
3. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 1
Vitamins
1) Which of the following is a fat soluble vitamin:
a) vitamin B12
b) vitamin C
c) vitamin A
2) All of the following vitamins are synthesized by intestinal bacteria except:
a) B12
b) K2
c) vitamin A
3) Deficiency of ………………leads to scurvy
a) vitamin K
b) vitamin C
c) vitamin A
4) Deficiency of ………………leads to pellagra
a) tryptophan
b) vitamin B3
c) vitamin B6
d) all of the above
5) Which of the following is an anti-oxidant vitamin:
a) vitamin E
b) vitamin B2
c) vitamin b12
6) Deficiency of ………………leads to rickets
a) vitamin K
b) vitamin D
c) vitamin A
7) The active form of vitamin d is :
a) calcitriol
b) 1 hydroxy cholecalciferol
c) 30 hydroxy cholecalciferol
4. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 2
8) Deficiency of ………………leads to night blindness
a) vitamin K
b) vitamin D
c) vitamin A
9) Vitamin is important to synthesis blood clotting factors is………
a) vitamin K
b) vitamin D
c) vitamin A
d) all of the above
10)The most important vitamin in carbohydrate metabolism is:
a) vitamin E
b) vitamin B1
c) vitamin b12
11)Vitamin which is required for nucleic acid synthesis is:
a) vitamin E
b) vitamin B1
c) vitamin b12
12)Deficiency of ………………leads to megaloblastic anemia
a) folic acid
b) vitamin B1
c) vitamin e
13)Which of the following vitamin is required in collagen synthesis:
a) vitamin K
b) vitamin C
c) vitamin A
14)Which of the following leads to vitamin k deficiency:
a) kidney disease
b) oral antibiotics
c) eating vegetables
15)Which of the following vitamin is required for healthy epithelium:
a) vitamin E
5. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 3
b) vitamin C
c) vitamin A
d) vitamin D
16)Vitamin A is used in treatment of:
a) oral leukoplakia
b) rickets
c) scurvy
17)…………is considered as hormone
a) vitamin C
b) vitamin D (calcitriol)
c) vitamin E
18)…………. Is essential for carboxylation reactions
a) vitamin B1
b) vitamin E
c) vitamin K
19)…………… Is essential for iron absorption
a) vitamin B1
b) vitamin C
c) vitamin K
20)Gums are severely affected in
a) beri beri
b) pellagra
c) scurvy
1 2 3 4 5 6 7 8
C C B B A B A C
9 10 11 12 13 14 15 16
A B C A B B C A
17 18 19 20
B C B C
6. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 4
Enzymes
1) Protein part of holoenzyme is called:
a) coenzyme
b) apoenzyme
c) heme part
2) All enzymes are………… in nature
a) carbohydrates
b) proteins
c) enzymes
3) Coenzyme act as a carrier to one carbon unit
a) TPP
b) NAD
c) FH4 (tetrahydrofolate)
4) Coenzyme act as a hydrogen carrier
a) TPP
b) NAD
c) FH4 (tetrahydrofolate)
5) Coenzyme important for carbohydrate metabolism
a) thiamine pyrophosphate (TPP)
b) NAD
c) FH4 (tetrahydrofolate)
6) Coenzyme important for protein metabolism
a) TPP
b) NAD
c) pyridoxal phosphate (PLP)
7) Not active form of enzyme is called
a) holoenzyme
b) zymogen
c) apoenzyme
7. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 5
8) Amylase is activated by
a) chloride b) magnesium c) copper
9) kinases are activated by
a) chloride b) magnesium c) copper
10)denaturation of enzyme leads to……………. Inhibition
a) competitive
b) reversible
c) irreversible
11)which of the following is a competitive inhibitor used in treatment of gout
a) allopurinol
b) warfarin
c) malonate
d) dicumoral
12)which of the following is a competitive inhibitor used as anticoagulant
a) allopurinol b) dicumoral c) malonate
13)the enzyme………..is used in treatment of myocardial infarction and deep vein thrombosis
a) helicase
b) streptokinase
c) glucose oxidase
14)……………. Is important in digestion of milk fat
a) carbonic angydrase
b) lingual lipase
c) histidase
15)…….. is elevated in blood in case of myocardial infarction
a) CK-MB
b) LDH-1
c) both of them
1 2 3 4 5 6 7 8
B B C B A C B A
9 10 11 12 13 14 15 16
B C A B B B C
8. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 6
Nucleic acid
1) Which of the following is the structure of the nueleotide?
a) A nitrogenous base like Purine or pyrimidine base + sugar + phosphoric acid
b) Purine or pyrimidine base + sugar
c) Purine or pyrimidine base + phosphoric acid
2) cAMP is formed by the enzyme
a) guanylyl cyclase
b) adenyl cyclase
c) arginase
3) ……….. is an acyl carrier
a) NAD
b) FAD
c) coenzyme A
4) Nucleotide which is important to lipid synthesis is
a) UTP
b) CTP
c) GTP
5) Nucleotides are joined together by :
a) ester bond (phosphodiester)
b) hydrogen bonds
c) peptide bonds
6) Nitrogenous bases are linked together by :
a) ester bond (phosphodiester)
b) hydrogen bonds
c) peptide bonds
7) …………. Is specific for carrying amino acids during protein synthesis
a) mRNA
b) rRNA
c) tRNA
9. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 7
8) …………… is called the genetic code
a) mRNA b) rRNA c) tRNA
9) The first amino acid in protein synthesis is :
a) alanine b) methionine c) arginine
10)Which of the following are the termination codons:
a) UAA, UAG, UGA
b) UAA, UCA, UAC
c) AUU. AUG, AUC
11)The end product of purine catabolism in human is
a) cytosine b) xanthine c) uracil
12)Purine salvage pathway occurs in :
a) RBCs
b) lung
c) heart
13)……………. Is used in treatment of gout
a) allopurinol
b) colchicine
c) both of them
14)allopurinol Is used in treatment of gout by inhibiting
a) xanthine oxidase enzyme
b) helicase
c) topoisomerase
15)secondary renal gout is due to:
a) congenital anomalies of kidney
b) lead poison
c) error in metabolism
1 2 3 4 5 6 7 8
A B C B A B C A
9 10 11 12 13 14 15 16
B A C A C A B
10. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 8
Genetics
1) RNA primer is formed by
a) primase
b) helicase
c) DNA polymerase
2) Thymine dimer is formed due to exposure to
a) ultraviolet rays
b) chemicals
c) mismatch
3) Xeroderma pigmetosum is caused by :
a) ultraviolet rays
b) chemicals
c) mismatch
4) HNPCC is due to:
a) ultraviolet rays b) chemicals c) mismatch
5) …………… is considered as a reverse transcriptase
a) telomerase enzyme
b) DNA polymerase III
c) primase
6) Unusual nitrogenous bases are present in :
a) mRNA
b) rRNA
c) tRNA
7) Faulty splicing of mRNA leads to
a) hemochromatosis
b) thalassemia
c) fibroadenoma
8) Tail of mRNA consist of:
a) guanine b) adenosine c) adenine
11. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 9
9) Substitution of single nitrogenous base leads to:
a) frame shift mutation
b) point mutation
c) non of them
10)Silent mutation may occurs due to………….. of genetic code
a) degeneracy b) specificity c) universality
11)Substance that increase rate of mutation and cancer is called :
a) mutagen
b) anti-oncogene
c) proto0oncogene
12)………………… is an example of an Anti-oncogene and prevent cancer
a) P53 gene
b) p512 gene
c) cyt p450
13) The main source of energy in protein synthesis is
a) CTP b) GTP c) ATP
14)Transcription is catalyzed by:
a) DNA polymerase
b) RNA polymerase
c) peptidyl transferase
15) Sex chromosomes in males are:
a) XX
b) XY
c) XYY
d) XXY
1 2 3 4 5 6 7 8
A A A C A C B C
9 10 11 12 13 14 15
B A A A B B B
12. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 10
Carbohydrates
2) Fructose is present on hydrolysis of
a) lactose
b) sucrose
c) maltose
d) starch
3) Galactose result from hydrolysis of:
a) lactose
b) sucrose
c) maltose
d) starch
4) A carbohydrate found in milk is:
a) lactose
b) sucrose
c) maltose
d) starch
5) A disaccharide made up of two glucose units is :
a) lactose
b) sucrose
c) maltose
d) starch
6) ………………….is used to reduce swellings and force urine production:
a) Maltose
b) mannitol.
c) Sucrose.
7) …………………. is non reducing sugar:
a) Glucose.
b) Mannose.
c) Sucrose.
13. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 11
8) Which of the following is homopolysaccharides present in animals ?
a) Dextrin.
b) Cellulose.
c) Glycogen.
d) Starch.
9) All of the following are characters of starch EXCEPT
a) homopolysaccharides.
b) present in animals
c) consists of glucose units.
d) give blue colour with iodine.
10) Cellulose is a
a) homopolysaccharide.
b) Heteropolysaccharide.
c) disaccharide.
d) Invert sugar.
11) All of the following are characters of glycogen EXCEPT
a) Homopolysaccharides.
b) present in animals
c) consists of B-glucose units. .
12) Heparin is:
a) glycosaminoglycans.
b) Heteropolysaccharide.
c) Anti-canticoagulant.
d) All of the above.
13) The sugar found in DNA iş:
a) ribose.
b) deoxyribose.
c) xylose.
d) ribulose.
14. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 12
14) Glycosaminoglycans present in skin is
a) heparin.
b) Chondroitin sufate.
c) Hyaluronic acid
d) Dermatan sulfate
15) Which of the following is marker for glomerular filtration rate?
a) dextran
b) chitin
c) Inulin
d) Glycolipid
16) Which of the following homopolysaccharides contain B-glucose?
a) Cellulose.
b) Starch.
c) Glycogen.
d) Deoxy-ribose
17) Digitalis is considered as
a) Glycosides.
b) Sugar acid.
c) Amino sugar
18) ……. Is a seetner and safe in diabetic patients:
a) glucose
b) glucovanillin
c) stevia
d) fructose
19) which of the following is sugar alcohol
a) gluconic acid
b) glucose
c) sorbitol
20) all of the fallowing are glycosaminoglycans except:
a) heparin b) hyaluronic acid c) cellulose
15. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 13
21) sugar acids are formed by……. Reaction :
a) reduction
b) oxidation
c) both
22) ……………….. is present in gangliosides
a) NANA b) deoxyribose c) galactose
23) reduction of fructose produce
a) sorbitol
b) mannitol
c) Both
24) General formula of monosaccharides is:
a) Cn-H2n-On
b) Cn-H2n-O
c) Cn-Hn-On
25) Which of the following carbohydrates is a triose?
a) Glucose
b) Ribose
c) Ribulose
d) Glyceraldehyde
26) Which of the following is an analogous to starch?
a) Cellulose
b) Glycogen
c) Sucrose
a) Chitin
27) The smallest monosaccharide is:
a) Glucose
b) Glyceraldehyde
c) Ribose
28) The most common monosaccharides are:
a) Trioses b) Hexoses c) Pentoses
16. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 14
29) …………..is the sugar of blood:
a) Mannose
b) fructose
c) glucose
d) Sulfur
30) …………….. don’t contain branches:
a) Cellulose b) Amyloses c) Both of them
31) All glycosaminoglycans are extra-cellular except:
a) Hyaluronic acid c) Heparin
b) Chondroitin sulfate d) Keratin sulfate
32) …………….. is sulfate free
a) Hyaluronic acid c) Heparin sulfate
b) Chondroitin sulfate d) Keratin sulfate
Answers
1) B
2) A
3) A
4) C
5) B
6) C
7) C
8) B
9) A
10) C
11) D
12) B
13) D
14) C
15) A
16) A
17) C
18) C
19) C
20) B
21) A
22) C
23) A
24) d
25) b
26) B
27) B
28) C
29) C
30) B
31) A
17. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 15
Lipids
1) ……….. is conditional essential fatty acid
a) Arachidonic acid
b) alanine
c) DHA
2) a fatty acid with 20 carbon atoms and four double bonds-
a) EPA
b) Arachidonic acid
c) DHA
3) All of the following have 18 carbon atoms except
a) Linoleic acid
b) Palmitic acid
c) Linolenic acid
d) Stearic acid
4) All are essential fatty acids except-
a)Linoleic,
b) Linolenic
c) Arachidonic acid
5) lecithin is a-
a) Cerebroside
b) Ganglioside
c) Phospholipid
d) Lipoprotein
6) Choose the correct statement
a) The melting point of a fatty acid increases with the increasing degree of unsaturation in
the hydrophobic chain
b) Most of the naturally fatty acids have trans double bonds
c) Arachidonic acid is a relatively nonessential fatty acid
d) The membrane lipids are rich in saturated fatty acids.
7) Which out of the following fatty acids is a precursor of Eicosanoids?
a) palmitic acid
18. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 16
b) Arachidonic acid
c) oleic acid
8) Which nitrogenous base out of the following is present in lecithin-?
a) Choline
b) Adenine
c)Ethanolamine
d) Any of the above
9) Which out of the following is an w 3 fatty acid?
a) Linolenic acid
b) Linoleic acid
c) Palmitic acid
d) Arachidonic acid
10)Which out of the following is an w 6 fatty acid?
a) Linolenic acid
b) Linoleic acid
c) Palmitic acid
11)Trans fats leads to
a) inflammation b) diabetes c) both
12)…………….. is important in signal transduction
a) phosphatidyl inositol b) lecithin c) cephalin
13)The normal level of serum Total cholesterol is ?
a) 150-220 mg/dl
b) 100-200 mg/dl
c) 1.5-2.5g/dl
d) 20-40 mg/dl
1 2 3 4 5 6 7 8
A B B C C C B A
9 10 11 12 13 14 15 16
A B C A A
19. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 17
Proteins
1) A sulfur containing tripeptide is :
a) alanine
b) glutathione
c) cysteine
2) ……………. Is genetically determined
a) 1ry structure
b) 2ry structure
c) 3ry structure
3) 1ry structure is stabilized by:
a) hydrogen bonds
b) peptide bonds
c) ionic bonds
4) The only purely ketogenic amino acid is:
a) histidine
b) leucine
c) lysine
5) Indol group is specific for:
a) tryptophan
b) serine
c) phenylalanine
6) Essential amino acid with OH is:
a) threonine
b) valine
c) phenylalanine
7) An imino group is present in:
a) proline
b) valine
c) serine
20. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 18
8) All of the following bonds stabilize tertiary structure except:
a) hydrogen bonds
b) di-sulfide bond
c) phosphodiester bond
9) Quaternary structure is present in:
a) hemoglobin
b) glutathione
c) denaturated protein
10) ………… is heterocyclic amino acid
a) histidine
b) aspartic acid
c) alanine
11) ……………… is amidic amino acid :
a) glutamic acid
b) glutamine
c) valine
12) ……………… is aliphatic basic amino acid:
a) arginine
b) aspartic acid
c) histidine
13) Two amino group are present in …………
a) glutamic
b) leucine
c) lysine
14) Which of the following is non protein amino acid :
a) arginine
b) ornithine
c) proline
21. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 19
15) …………… is positively charged:
a) histidine
b) proline
c) aspartic acid
16) Which of the following is semi-essential amino acids:
a) histidine
b) Methionine
c) alanine
17) Positively charged amino acids are :
a)lysine, arginine
b) lysine, aspargine
c) glutamine, arginine
18) Imidiazole ring is present in
a) tryptophan
b) histidine
c) arginine
19) Guanidine ring is present in :
a) tryptophan
b) histidine
c) arginine
20) All of the following enter in structure of glutathione except:
a) glutamic b) cysteine
c) glycine d) histidine
21) All of the following are biologically active peptide except:
a) ACTH
b) thyroxin
c) endorphins
22) ……………. Is due to defect fibrillin protein:
a) marfan syndrome
b) von geirk
22. Bio-Philic Dr. Ibrahim El-Husseiny
Smart Not Hard 20
c) lesh nyhan
23) ……………act as neurotransmitter
a) GABA
b) Alanine
c) glutmate
24) High biological value proteins are rich in :
a) essential amino acids
b) non essential amino acids
c) alanine
25) Which of the following is a phosphoprotein
a) albumin
b) casein
c) ceruloplasmin
Answers
1) B
2) A
3) B
4) B
5) A
6) A
7) A
8) C
9) A
10) A
11) B
12) A
13) C
14) B
15) A
16) A
17) A
18) B
19) C
20) d
21) B
22) a
23) A
24) a
25) B