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INTEGUMENTARY SYSTEM
PATH-321
1
KHAWAJA TAIMOOR SHAHID
By
2
Infections of the skin
1. Cellulitis
• Is a diffuse, acute streptococcal or staphylococcal
infection of the skin and subcutaneous tissue.
Cause
• Causedbybacteria’slikestreptococcus/staphylococcus aureus
• Results from break in skin
• Infection rapidly spread through lymphatic system
Sign and symptoms
• Tender, red, hot, indurated and swollen area that is well
demarcated
• Possible fluctuant abscess or purulent drainage
• Fever, chills
Features:
Red
Swollen
Warm to touch
No areas of
pus
Painful
Tender
3
Theresult of “skin popping” -
Multiple injection site
abscesses
4
Cellulitis with
abscess
5
If rapid spreading beyond this line occurs, this may be
necrotizing , and requires surgery
2. Furunclosis
• Is an acute painful infection of perifollicular abscess (boils)
• Is an acute, localized, deep seated, red, hot, very tender,
inflammatory perifollicular abscess.
• Common microorganism: staphylococcus aureus
• Most common on persons who are carriers of staphylococcus,
contact with oils or grease, diabetes, poor habits of personal
hygiene, immunosuppression, alcoholism, obese, malnutrition
etc.
• The lesion begins in the opening of hair follicle or
sebaceous gland
• Sites can be back of the neck, face, buttocks, thighs, breasts,
axilla, nose, genitalia, etc
81
Sign and symptoms
• Hard nodule initially then fluctuant abscess with centrally
yellow pustule, then ruptures in to an ulcer.
• It can be isolated single lesion or few multiple lesion
• Hotness and pain at the site.
KHAWAJA TAIMOOR SHAHID
3. Carbuncles
(multiple furuncles)
- Is an aggregation of interconnected furuncles that drain through
multiple openings in the skin.
• Exposure to grease and oil increase the risk.
• Occurs mostly where the skin is thick
• Microorganism mostly: Staph. Aureus
Sign and symptoms
• Sites are back of the neck, shoulder, buttock, outer aspect of the
thigh and over the hip joints.
• Develop slowly than furuncle.
• They can reach the size of an egg/small orange.
• Fever, chills, extreme pain.
• Because of the large size of the lesion and its delayed drainage the
patient is much sicker
HA(MS
N)
10
11
4.Folliculitis
• Is inflammation of the hair follicle
Sign and symptom
– Single or multiple papules or pustules
– Commonly seen in the beard area of men and
women’s legs from shaving
12
13
5. Impetigo
• Is an acute, contagious, rapidly spreading cutaneous
infection and is a very common bacterial infection of
the superficial skin
• Causative agents are stap. aureus or a B-hemolytic
streptococcus or both
Sign and Symptom
• Superficial pustules or blisters which becomes oozing with
yellow crusts
• Contagious
• Blisters break easily and form golden crusts
HA(MS
N)
14
HA(MS
N)
15
16
Fungal skin disorder
1. Dermatophytoses (Mycoses)
• Is a fungal infection of the skin, hair and nails
Types
a. Tinea pedis (Athlete’sfoot)
• Is itchy, whitish scaling lesions and inflammation of the
superficial skin of the feet and interdigital spaces of the toes
• Common between the 4th and 5th toe.
• Often seen in people wearing rubber
boots/shoes
17
18
b. Tinea corporis (Tinea circinata)
• A fungal infection that affects the trunk, legs, arms/neck,
excluding the beard area, feet and hands.
– Is fungal infection of the skin most common on the
exposed surfaces of the body.
– Sites are face, arms and shoulders.
– Intensive itching is there
• Frequent causes of tinea corporis is the prescence of
an infected pet in the home
KHAWAJA TAIMOOR SHAHID
HA(MS
N)
19
20
c. Tinea capitis (ring worm)
• Is a contagious fungal disease of the scalp and hair shaft
Sign and symptom
• One or more round patches with scaling
• alopecia
• Lymphnodes in the neck swell and the patient may have fever
and headache
21
22
d. Tinea unguium
- Is a chronic fungal and sometimes mixed yeast
infection of the toe/finger nails
• Is commonly occurs in people who frequently wet the hands
such as domestic workers, cleaners, kitchen and laundary
staff.
Sign and Symptom
• Nail become thickened, friable (easily crumbled),
lusterless.
• Accumulation of debris under the free edge of the nail
• The nail may be destroyed.
23
24
e. Tinea versicolor (pityriasis versicolor)
• Is a common chronic superficial fungal infection which is caused
by the unicellular yeast pityrosporum ovale or orbiculare which is
normally present on the trunk as a commensal.
• Often there is cosmetic complaints.
Sign and Symptoms
• Appears commonly when there is warm and humid air,
pregnancy, and serious underlying disease.
• Hypo-pigmented macule on the trunk
• Disturbance of the pigment of the skin (versicolor)
• Recurrences are common especially after in adequate
treatment or re-infection.
25
26
f. Tinea cruris (Jack itch)
• A fungal infection of the pubic region and thighs
• Sign and symptom
• Scaling at the periphery
• A patch that may spread to buttocks
• Itching and irritation
27
g. Tinea barbae
• Is a fungal infection involving the beard
• Affects males only
• More common in farmers
Sign and symptom
• Pruritis
• Tenderness and pain
• Pustular folliculitis around the hair follicle
• Involved hairs are loose and easily removed.
28
29
h. Candidiasis /moniliasis/
• Candida albicans is a resident of the mucus membranes,
it becomes pathogenic under favourable host condition
these are:
– When host immunity is decreased, such as HIV, cancer, steroid
use, cytotoxic drugs, radiotherapy, chronic disease, pregnancy
and contraceptive pill use
– Warm and moisture (under breasts, b/n toes)
– Use of broad spectrum antibiotics which kills resident non
pathogenic bacteria
KHAWAJA TAIMOOR SHAHID
HA(MS
N)
30
31
Sign and Symptom
• On the oral (oral candidiasis/thrush)- white cheesy
adherent plaque that can be painful
• When oral lesions extend to the throat and esophagus, they
can cause anorexia, nausea, dysphagia, and vomiting
• On the vulvo-vagina (candidia vulvovaginitis)- vaginal
irritation, soreness and a thick creamy discharge
32
Parasitic skin disorder
a. Scabies
• Is an infection of the skin caused by a parasite called mite
sarcoptes scabiei, a mite which lays its eggs in burrow in the
stratum and induces an intensively itchy allergic respons.
Sign and Symptom
• Small blisters and papules
• Sever itching, when warm particularly at night
• Scratch marks and very common secondary
infection with pustules
• Common sites are between fingers, sides of the hands, sides
of the wrists, buttocks
33
b. Pediculosis
• Is an infestation with a louse which may be found in the:
• Scalp-
• Body-
• Hair bearing region-
Sign and symptom
• Itching (excoriation)
• The presence of lice
• Over crowding, poor personal hygiene, prolonged wearing of the
same clothes.
34
f.Viral skin disorders
• It is an acute contagious short lived (7-12 days) infection of the
skin or mucus membrane caused by virus
Types:
a. Herpes simplex
• Is an infection which is caused by herpes simplex virus that
causes vesicular eruption (cold sore or fever blister) on lip
(herpes labialis), and on genitalia (herpes genitalia)
Sign and Symptoms
- Few days of burning sensation at the site initially.
- Then a group of blisters appear which quickly break down to
form superficial ulcer
- Highly contagious when the lesions are visible.
Cold sores
37
b. Herpes zoster (shingles)
• Is an acute unilateral and segmental inflammation of the
dorsal root ganglia of a nerve by a latent varicella zoster
infection in the partially immune host.
Sign and symptoms
• A localized vesicles in cluster form on one side of the
body/unilateral.
• Itching, tenderness and severe pain on the site.
• The thoracic, cervical and ophthalmic nerves are frequently
affected.
• After 1-2 weeks crusts begin to fall off with residual scaring.
• Over 10% of patients develop a persistent burning
sensation.
• Much more common in HIV patients, old patients and
malignancy cases.
38
39
c. Verrucae /Warts/
• Are common benign skin tumors caused by infection with the Human
Papilloma Virus.
Types:
1. Plantar warts- warts on the sole of the foot
2. Plane (flat/Juvenile) warts- warts on the face of children
3. Genital warts/condylomata acuminate/- warts that appear on genital
organs
4. Molluscum contagiosum- a wart which appear on small children which
has typical characteristics of dome shaped papules.
Sign and symptom
• Found at any age but most common in children and teenagers
• They can spread by contact
• The infected person immune system clears the warts with in 2
years in 2/3 cases
HA(MS
N)
40
41
G. Skin cancer
• Cancer is a disease of the cell in which the normal mechanism of
control of growth and proliferation are disturbed.
• The malignant cell is able to invade the surrounding tissue and
regional lymph nodes.
• Metastasis is the secondary growth of the primary
cancer in another organ.
• Skin assessment-20-39 age-every 3 years
• >40 age-annually
KHAWAJA TAIMOOR SHAHID
SUPERIOR COLLEGE
M.B.DiN

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3. lec 4 integument system PATH-321.pptx

  • 2. 2 Infections of the skin 1. Cellulitis • Is a diffuse, acute streptococcal or staphylococcal infection of the skin and subcutaneous tissue. Cause • Causedbybacteria’slikestreptococcus/staphylococcus aureus • Results from break in skin • Infection rapidly spread through lymphatic system Sign and symptoms • Tender, red, hot, indurated and swollen area that is well demarcated • Possible fluctuant abscess or purulent drainage • Fever, chills
  • 3. Features: Red Swollen Warm to touch No areas of pus Painful Tender 3
  • 4. Theresult of “skin popping” - Multiple injection site abscesses 4
  • 5. Cellulitis with abscess 5 If rapid spreading beyond this line occurs, this may be necrotizing , and requires surgery
  • 6. 2. Furunclosis • Is an acute painful infection of perifollicular abscess (boils) • Is an acute, localized, deep seated, red, hot, very tender, inflammatory perifollicular abscess. • Common microorganism: staphylococcus aureus • Most common on persons who are carriers of staphylococcus, contact with oils or grease, diabetes, poor habits of personal hygiene, immunosuppression, alcoholism, obese, malnutrition etc. • The lesion begins in the opening of hair follicle or sebaceous gland • Sites can be back of the neck, face, buttocks, thighs, breasts, axilla, nose, genitalia, etc 81
  • 7.
  • 8. Sign and symptoms • Hard nodule initially then fluctuant abscess with centrally yellow pustule, then ruptures in to an ulcer. • It can be isolated single lesion or few multiple lesion • Hotness and pain at the site. KHAWAJA TAIMOOR SHAHID
  • 9. 3. Carbuncles (multiple furuncles) - Is an aggregation of interconnected furuncles that drain through multiple openings in the skin. • Exposure to grease and oil increase the risk. • Occurs mostly where the skin is thick • Microorganism mostly: Staph. Aureus Sign and symptoms • Sites are back of the neck, shoulder, buttock, outer aspect of the thigh and over the hip joints. • Develop slowly than furuncle. • They can reach the size of an egg/small orange. • Fever, chills, extreme pain. • Because of the large size of the lesion and its delayed drainage the patient is much sicker
  • 11. 11 4.Folliculitis • Is inflammation of the hair follicle Sign and symptom – Single or multiple papules or pustules – Commonly seen in the beard area of men and women’s legs from shaving
  • 12. 12
  • 13. 13 5. Impetigo • Is an acute, contagious, rapidly spreading cutaneous infection and is a very common bacterial infection of the superficial skin • Causative agents are stap. aureus or a B-hemolytic streptococcus or both Sign and Symptom • Superficial pustules or blisters which becomes oozing with yellow crusts • Contagious • Blisters break easily and form golden crusts
  • 16. 16 Fungal skin disorder 1. Dermatophytoses (Mycoses) • Is a fungal infection of the skin, hair and nails Types a. Tinea pedis (Athlete’sfoot) • Is itchy, whitish scaling lesions and inflammation of the superficial skin of the feet and interdigital spaces of the toes • Common between the 4th and 5th toe. • Often seen in people wearing rubber boots/shoes
  • 17. 17
  • 18. 18 b. Tinea corporis (Tinea circinata) • A fungal infection that affects the trunk, legs, arms/neck, excluding the beard area, feet and hands. – Is fungal infection of the skin most common on the exposed surfaces of the body. – Sites are face, arms and shoulders. – Intensive itching is there • Frequent causes of tinea corporis is the prescence of an infected pet in the home KHAWAJA TAIMOOR SHAHID
  • 20. 20 c. Tinea capitis (ring worm) • Is a contagious fungal disease of the scalp and hair shaft Sign and symptom • One or more round patches with scaling • alopecia • Lymphnodes in the neck swell and the patient may have fever and headache
  • 21. 21
  • 22. 22 d. Tinea unguium - Is a chronic fungal and sometimes mixed yeast infection of the toe/finger nails • Is commonly occurs in people who frequently wet the hands such as domestic workers, cleaners, kitchen and laundary staff. Sign and Symptom • Nail become thickened, friable (easily crumbled), lusterless. • Accumulation of debris under the free edge of the nail • The nail may be destroyed.
  • 23. 23
  • 24. 24 e. Tinea versicolor (pityriasis versicolor) • Is a common chronic superficial fungal infection which is caused by the unicellular yeast pityrosporum ovale or orbiculare which is normally present on the trunk as a commensal. • Often there is cosmetic complaints. Sign and Symptoms • Appears commonly when there is warm and humid air, pregnancy, and serious underlying disease. • Hypo-pigmented macule on the trunk • Disturbance of the pigment of the skin (versicolor) • Recurrences are common especially after in adequate treatment or re-infection.
  • 25. 25
  • 26. 26 f. Tinea cruris (Jack itch) • A fungal infection of the pubic region and thighs • Sign and symptom • Scaling at the periphery • A patch that may spread to buttocks • Itching and irritation
  • 27. 27 g. Tinea barbae • Is a fungal infection involving the beard • Affects males only • More common in farmers Sign and symptom • Pruritis • Tenderness and pain • Pustular folliculitis around the hair follicle • Involved hairs are loose and easily removed.
  • 28. 28
  • 29. 29 h. Candidiasis /moniliasis/ • Candida albicans is a resident of the mucus membranes, it becomes pathogenic under favourable host condition these are: – When host immunity is decreased, such as HIV, cancer, steroid use, cytotoxic drugs, radiotherapy, chronic disease, pregnancy and contraceptive pill use – Warm and moisture (under breasts, b/n toes) – Use of broad spectrum antibiotics which kills resident non pathogenic bacteria KHAWAJA TAIMOOR SHAHID
  • 31. 31 Sign and Symptom • On the oral (oral candidiasis/thrush)- white cheesy adherent plaque that can be painful • When oral lesions extend to the throat and esophagus, they can cause anorexia, nausea, dysphagia, and vomiting • On the vulvo-vagina (candidia vulvovaginitis)- vaginal irritation, soreness and a thick creamy discharge
  • 32. 32 Parasitic skin disorder a. Scabies • Is an infection of the skin caused by a parasite called mite sarcoptes scabiei, a mite which lays its eggs in burrow in the stratum and induces an intensively itchy allergic respons. Sign and Symptom • Small blisters and papules • Sever itching, when warm particularly at night • Scratch marks and very common secondary infection with pustules • Common sites are between fingers, sides of the hands, sides of the wrists, buttocks
  • 33. 33 b. Pediculosis • Is an infestation with a louse which may be found in the: • Scalp- • Body- • Hair bearing region- Sign and symptom • Itching (excoriation) • The presence of lice • Over crowding, poor personal hygiene, prolonged wearing of the same clothes.
  • 34. 34
  • 35. f.Viral skin disorders • It is an acute contagious short lived (7-12 days) infection of the skin or mucus membrane caused by virus Types: a. Herpes simplex • Is an infection which is caused by herpes simplex virus that causes vesicular eruption (cold sore or fever blister) on lip (herpes labialis), and on genitalia (herpes genitalia) Sign and Symptoms - Few days of burning sensation at the site initially. - Then a group of blisters appear which quickly break down to form superficial ulcer - Highly contagious when the lesions are visible.
  • 37. 37 b. Herpes zoster (shingles) • Is an acute unilateral and segmental inflammation of the dorsal root ganglia of a nerve by a latent varicella zoster infection in the partially immune host. Sign and symptoms • A localized vesicles in cluster form on one side of the body/unilateral. • Itching, tenderness and severe pain on the site. • The thoracic, cervical and ophthalmic nerves are frequently affected. • After 1-2 weeks crusts begin to fall off with residual scaring. • Over 10% of patients develop a persistent burning sensation. • Much more common in HIV patients, old patients and malignancy cases.
  • 38. 38
  • 39. 39 c. Verrucae /Warts/ • Are common benign skin tumors caused by infection with the Human Papilloma Virus. Types: 1. Plantar warts- warts on the sole of the foot 2. Plane (flat/Juvenile) warts- warts on the face of children 3. Genital warts/condylomata acuminate/- warts that appear on genital organs 4. Molluscum contagiosum- a wart which appear on small children which has typical characteristics of dome shaped papules. Sign and symptom • Found at any age but most common in children and teenagers • They can spread by contact • The infected person immune system clears the warts with in 2 years in 2/3 cases
  • 41. 41 G. Skin cancer • Cancer is a disease of the cell in which the normal mechanism of control of growth and proliferation are disturbed. • The malignant cell is able to invade the surrounding tissue and regional lymph nodes. • Metastasis is the secondary growth of the primary cancer in another organ. • Skin assessment-20-39 age-every 3 years • >40 age-annually KHAWAJA TAIMOOR SHAHID SUPERIOR COLLEGE M.B.DiN