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Age and cause contributions of lower life expectancy
           in Inuit Nunangat, 1989-2003


   National Aboriginal Health Organisation
                   November 24th, 2009
                       Ottawa, ON


                       Paul A. Peters, PhD
             Health Analysis Division, Statistics Canada
Outline


 Objective
      • To measure the contributions of age groups and
        causes of death to differences life expectancy
        between residents of Inuit Nunangat and the rest of
        Canada
 Rationale
      • Life expectancy for residents of Inuit Nunangat is
        lower than for residents in the rest of Canada
             Specific causes of death in certain age groups are thought to
              contribute to this difference



November 24, 2009                                                        2/19
November 24, 2009   3/19
Data sources


 Deaths:
      • Canadian Mortality Database
      • Three 5-year periods:
             Centred on census years 1991, 1996, 2001 (1989-2003)
      • Census subdivision code for usual place of residence
 Population (person-years)
      • Multiplied by factor of five for each mid-period census
      • Mid-year population counts from census




November 24, 2009                                                    4/19
Methods
- Analytic techniques
 Life expectancy
      • Standard abridged life tables (Chiang adjusted)
 Cause decomposition
      • What cause-specific mortality differences contribute
        to total differences in life expectancy?
             Contribution of specific causes of death to the total years of
              difference between life expectancies
      • Arriaga (1989) method from discrete life tables




November 24, 2009                                                          5/19
Methods
- Causes of death
 Global Burden of Disease
      • Causes of death aggregated in a way that underpins
        human development rather than the body system
             I – Communicable, maternal, perinatal, and nutritional
             II – Noncommunicable diseases
             III – Injuries
 Attributable Causes of Death
      • Mackenbach et al. 2008 NEJM.
             Smoking-related
             Alcohol-related
             Medically amenable deaths (appendicitis, diabetes, etc…)

November 24, 2009                                                        6/19
Results
     - Life expectancy
                                  Inuit Nunangat                              Canada                Difference
                         Years (A)           95% confidence       Years (B)       95% confidence              A-B
1989-1993                                           interval                             interval
 Males                          66.5        (65.1     to 67.9)        74.2       (74.2   to 74.2)             -7.7
 Females                        71.5        (70.0     to 73.1)        80.6       (80.6   to 80.7)             -9.1
1994-1998
 Males                          64.7        (63.3     to 65.7)        74.6       (74.6   to 74.6)        -10.1
 Females                        70.7        (69.4     to 72.1)        79.8       (79.7   to 79.8)             -9.0
1999-2003
 Males                          64.7        (63.4     to 65.9)        76.6       (76.5   to 76.6)        -11.9
 Females                        69.9        (68.7     to 71.1)        81.8       (81.8   to 81.9)        -11.9
Sources: Statistics Canada, Vital Statistics - Deaths Database;

         Statistics Canada, Census of Population




    November 24, 2009                                                                                  7/19
Results
- Cause contributions (male)
                                                                 15
         Contribution to difference in life expectancy (years)




                                                                 10



                                                                                                                                     7.5
                                                                                                             5.6

                                                                 5           4.1



                                                                             1.9                             3.1                     2.8

                                                                             1.2                             0.9                     0.7
                                                                 0
                                                                         1989-1993                        1994-1998               1999-2003

                                                                      Communicable, maternal, perinatal, nutritional   Noncommunicable        Injuries




November 24, 2009                                                                                                                                        8/19
Results
- Cause contributions (years, male)
Cause of death                                          1989-1993    1994-1998    1999-2003
Total difference                                               7.7         10.1         11.9
I. Communicable, maternal, perinatal, and nutritional          1.2          0.9          0.7
  Respiratory infections                                       0.6          0.4          0.2
  Perinatal conditions                                         0.3          0.4          0.2
  Other communicable, maternal, and nutritional                0.3          0.2          0.4
II. Noncommunicable diseases                                   1.9          3.1          2.8
  Malignant neoplasms                                          1.2          1.2          1.4
     Colon and rectum cancers                                  0.0          0.1          0.2
     Trachea, bronchus, and lung                               1.1          0.6          1.0
     Other malignant neoplasms                                 0.6          0.8          0.4
  Neuro-psychiatric conditions                                 0.3          0.3          0.2
  Cardiovascular diseases                                      0.1          0.9          0.5
     Ischaemic heart disease                                  -0.7          0.3         -0.1
     Cerebrovascular disease                                   0.2          0.4          0.2
     Other cardiovascular diseases                             0.9          0.7          0.6
  Respiratory diseases                                         0.5          0.7          0.7
     COPD                                                      0.5          0.5          0.5
     Other respiratory diseases                                0.1          0.2          0.2
  Congenital abnormalities                                     0.2          0.2          0.2
  Other noncommunicable diseases                               0.1          0.1          0.2
III. Injuries                                                  4.1          5.6          7.5
  Unintentional injuries                                       1.6          2.6          2.3
  Intentional injuries                                         2.4          3.0          5.3
     Self-inflicted injuries                                   2.1          2.9          5.0
     Other intentional injuries                                0.4          0.2          0.3
Results
- Cause contributions (female)
                                                                 15
         Contribution to difference in life expectancy (years)




                                                                                                                                     2.9
                                                                 10

                                                                             1.8
                                                                                                              2.4

                                                                                                                                     8.0
                                                                 5
                                                                             6.1
                                                                                                              5.1



                                                                             1.0                              1.0                    1.4
                                                                 0
                                                                         1989-1993                        1994-1998               1999-2003

                                                                      Communicable, maternal, perinatal, nutritional   Noncommunicable        Injuries




November 24, 2009                                                                                                                                        10/19
Results
- Cause contributions (years, female)
Cause of death                                          1989-1993    1994-1998    1999-2003
Total difference                                               9.1          9.0         11.9
I. Communicable, maternal, perinatal, and nutritional          1.0          1.0          1.4
  Respiratory infections                                       0.3          0.4          0.5
  Perinatal conditions                                         0.3          0.2          0.3
  Other communicable, maternal, and nutritional                0.4          0.5          0.6
II. Noncommunicable diseases                                   6.1          5.1          8.0
  Malignant neoplasms                                          1.4          2.0          3.6
     Colon and rectum cancers                                  0.2          0.2          0.6
     Trachea, bronchus, and lung                               1.1          1.7          2.1
     Other malignant neoplasms                                 1.1          1.0          1.4
  Neuro-psychiatric conditions                                 0.3          0.3          0.3
  Cardiovascular diseases                                      1.5          0.5          1.3
     Ischaemic heart disease                                  -0.1         -0.2          0.1
     Cerebrovascular disease                                   0.6          0.1          0.7
     Other cardiovascular diseases                             1.4          1.0          0.5
  Respiratory diseases                                         2.9          1.9          2.1
     COPD                                                      2.4          1.6          1.8
     Other respiratory diseases                                0.5          0.4          0.3
  Congenital abnormalities                                     0.3          0.1          0.3
  Other noncommunicable diseases                               0.5          0.8          0.6
III. Injuries                                                  1.8          2.4          2.9
  Unintentional injuries                                       0.9          1.3          1.5
  Intentional injuries                                         0.7          1.1          1.4
     Self-inflicted injuries                                   0.5          0.9          1.3
     Other intentional injuries                                0.3          0.2          0.1
Results
- Attributable cause contributions
                                                                                                   Males
                                                                 5
            Contribution to life expectancy difference (years)




                                                                 4




                                                                 3



                                                                 2                                                                   1.9
                                                                     1.7
                                                                                                    1.5


                                                                 1                 0.9
                                                                                                                    0.7
                                                                                                                                                 0.5
                                                                           0.2
                                                                                                           0.1                             0.1
                                                                 0
                                                                       1989-1993                      1994-1998                        1999-2003

                                                                                         Smoking          Alcohol         Amenable




November 24, 2009                                                                                                                                      12/19
Results
- Attributable cause contributions
                                                                                                 Females
                                                                 5
            Contribution to life expectancy difference (years)




                                                                     4.0                                                           4.1
                                                                 4
                                                                                                  3.6


                                                                 3



                                                                 2                                                                             1.7


                                                                                 1.0
                                                                 1
                                                                                                                  0.6
                                                                           0.2                           0.2                             0.3

                                                                 0
                                                                       1989-1993                    1994-1998                        1999-2003

                                                                                       Smoking          Alcohol         Amenable




November 24, 2009                                                                                                                                    13/19
Contribution to difference in life
                                                        expectancy (%)




November 24, 2009
                                       -5
                                                    0
                                                           5
                                                                     10
                                                                               15
                                                                                     20
                                              <1
                                                                                          Results



                                              1-4

                                              5-9

                                            10-14

                                            15-19

                                            20-24

                                            25-29




                    1991
                                            30-34

                                            35-39




                    1996
                                            40-44

                                            45-49

                           Age group

                    2001
                                            50-54

                                            55-59

                                            60-64

                                            65-69

                                            70-74

                                            75-79

                                            80-84

                                            85-89

                                             90+
                                                                                          - Age contributions (males, percent)




   14/19
Contribution to difference in life
                                                        expectancy (%)




November 24, 2009
                                       -5
                                                    0
                                                           5
                                                                     10
                                                                               15
                                                                                     20
                                              <1
                                                                                          Results



                                              1-4

                                              5-9

                                            10-14

                                            15-19

                                            20-24

                                            25-29




                    1991
                                            30-34

                                            35-39




                    1996
                                            40-44

                                            45-49

                           Age group

                    2001
                                            50-54

                                            55-59

                                            60-64

                                            65-69

                                            70-74

                                            75-79

                                            80-84

                                            85-89

                                             90+
   15/19
                                                                                          - Age contributions (females, percent)
Discussion


 Life expectancy difference appears to be
  increasing between Inuit Nunangat & Canada
 Difference is related to specific causes of death
      • Males – injury & suicide are major contributors
             Injury and suicide account for 7.5 years of difference
      • Females – chronic diseases are major contributors
             Lung cancer and COPD account for 4 years of difference
 Specific causes differ between sexes
      • Smoking-related diseases for females
      • Alcohol-related diseases are not major contributors

November 24, 2009                                                      16/19
Discussion


 Difference is concentrated in specific age groups
      • Males – mortality between 15 and 29 is key
             1/3 of difference due to mortality between 15 and 29 years
             This is largely due to injury and suicide
      • Females – mortality after age 60 contributes most
             50% of difference due to mortality after 60 years of age
             This is largely due to chronic diseases




November 24, 2009                                                          17/19
Limitations


 Limits to geographic approach
      • For all residents of Inuit Nunangat, not just Inuit
      • Unequal access to health services
      • Older population may move “south” for care
 Reliability of vital statistics
      • Cause of death coding may vary between periods
 Use of a comparable population
      • Comparison to other isolated communities, other
        Aboriginal groups, or other countries


November 24, 2009                                             18/19
Acknowledgements


 Contact:
      • Paul A. Peters, PhD
        Health Analysis Division
        Statistics Canada
        Ottawa, ON
        (613) 951-0616
        paul.a.peters@statcan.gc.ca


 Thanks to: Health Canada FNIHB
           (Jennifer Pennock, Neil Goedhuis)

November 24, 2009                              19/19

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Age and cause contributions of lower life expectancy in Inuit Nunangat, 1989-2003

  • 1. Age and cause contributions of lower life expectancy in Inuit Nunangat, 1989-2003 National Aboriginal Health Organisation November 24th, 2009 Ottawa, ON Paul A. Peters, PhD Health Analysis Division, Statistics Canada
  • 2. Outline  Objective • To measure the contributions of age groups and causes of death to differences life expectancy between residents of Inuit Nunangat and the rest of Canada  Rationale • Life expectancy for residents of Inuit Nunangat is lower than for residents in the rest of Canada  Specific causes of death in certain age groups are thought to contribute to this difference November 24, 2009 2/19
  • 4. Data sources  Deaths: • Canadian Mortality Database • Three 5-year periods:  Centred on census years 1991, 1996, 2001 (1989-2003) • Census subdivision code for usual place of residence  Population (person-years) • Multiplied by factor of five for each mid-period census • Mid-year population counts from census November 24, 2009 4/19
  • 5. Methods - Analytic techniques  Life expectancy • Standard abridged life tables (Chiang adjusted)  Cause decomposition • What cause-specific mortality differences contribute to total differences in life expectancy?  Contribution of specific causes of death to the total years of difference between life expectancies • Arriaga (1989) method from discrete life tables November 24, 2009 5/19
  • 6. Methods - Causes of death  Global Burden of Disease • Causes of death aggregated in a way that underpins human development rather than the body system  I – Communicable, maternal, perinatal, and nutritional  II – Noncommunicable diseases  III – Injuries  Attributable Causes of Death • Mackenbach et al. 2008 NEJM.  Smoking-related  Alcohol-related  Medically amenable deaths (appendicitis, diabetes, etc…) November 24, 2009 6/19
  • 7. Results - Life expectancy Inuit Nunangat Canada Difference Years (A) 95% confidence Years (B) 95% confidence A-B 1989-1993 interval interval Males 66.5 (65.1 to 67.9) 74.2 (74.2 to 74.2) -7.7 Females 71.5 (70.0 to 73.1) 80.6 (80.6 to 80.7) -9.1 1994-1998 Males 64.7 (63.3 to 65.7) 74.6 (74.6 to 74.6) -10.1 Females 70.7 (69.4 to 72.1) 79.8 (79.7 to 79.8) -9.0 1999-2003 Males 64.7 (63.4 to 65.9) 76.6 (76.5 to 76.6) -11.9 Females 69.9 (68.7 to 71.1) 81.8 (81.8 to 81.9) -11.9 Sources: Statistics Canada, Vital Statistics - Deaths Database; Statistics Canada, Census of Population November 24, 2009 7/19
  • 8. Results - Cause contributions (male) 15 Contribution to difference in life expectancy (years) 10 7.5 5.6 5 4.1 1.9 3.1 2.8 1.2 0.9 0.7 0 1989-1993 1994-1998 1999-2003 Communicable, maternal, perinatal, nutritional Noncommunicable Injuries November 24, 2009 8/19
  • 9. Results - Cause contributions (years, male) Cause of death 1989-1993 1994-1998 1999-2003 Total difference 7.7 10.1 11.9 I. Communicable, maternal, perinatal, and nutritional 1.2 0.9 0.7 Respiratory infections 0.6 0.4 0.2 Perinatal conditions 0.3 0.4 0.2 Other communicable, maternal, and nutritional 0.3 0.2 0.4 II. Noncommunicable diseases 1.9 3.1 2.8 Malignant neoplasms 1.2 1.2 1.4 Colon and rectum cancers 0.0 0.1 0.2 Trachea, bronchus, and lung 1.1 0.6 1.0 Other malignant neoplasms 0.6 0.8 0.4 Neuro-psychiatric conditions 0.3 0.3 0.2 Cardiovascular diseases 0.1 0.9 0.5 Ischaemic heart disease -0.7 0.3 -0.1 Cerebrovascular disease 0.2 0.4 0.2 Other cardiovascular diseases 0.9 0.7 0.6 Respiratory diseases 0.5 0.7 0.7 COPD 0.5 0.5 0.5 Other respiratory diseases 0.1 0.2 0.2 Congenital abnormalities 0.2 0.2 0.2 Other noncommunicable diseases 0.1 0.1 0.2 III. Injuries 4.1 5.6 7.5 Unintentional injuries 1.6 2.6 2.3 Intentional injuries 2.4 3.0 5.3 Self-inflicted injuries 2.1 2.9 5.0 Other intentional injuries 0.4 0.2 0.3
  • 10. Results - Cause contributions (female) 15 Contribution to difference in life expectancy (years) 2.9 10 1.8 2.4 8.0 5 6.1 5.1 1.0 1.0 1.4 0 1989-1993 1994-1998 1999-2003 Communicable, maternal, perinatal, nutritional Noncommunicable Injuries November 24, 2009 10/19
  • 11. Results - Cause contributions (years, female) Cause of death 1989-1993 1994-1998 1999-2003 Total difference 9.1 9.0 11.9 I. Communicable, maternal, perinatal, and nutritional 1.0 1.0 1.4 Respiratory infections 0.3 0.4 0.5 Perinatal conditions 0.3 0.2 0.3 Other communicable, maternal, and nutritional 0.4 0.5 0.6 II. Noncommunicable diseases 6.1 5.1 8.0 Malignant neoplasms 1.4 2.0 3.6 Colon and rectum cancers 0.2 0.2 0.6 Trachea, bronchus, and lung 1.1 1.7 2.1 Other malignant neoplasms 1.1 1.0 1.4 Neuro-psychiatric conditions 0.3 0.3 0.3 Cardiovascular diseases 1.5 0.5 1.3 Ischaemic heart disease -0.1 -0.2 0.1 Cerebrovascular disease 0.6 0.1 0.7 Other cardiovascular diseases 1.4 1.0 0.5 Respiratory diseases 2.9 1.9 2.1 COPD 2.4 1.6 1.8 Other respiratory diseases 0.5 0.4 0.3 Congenital abnormalities 0.3 0.1 0.3 Other noncommunicable diseases 0.5 0.8 0.6 III. Injuries 1.8 2.4 2.9 Unintentional injuries 0.9 1.3 1.5 Intentional injuries 0.7 1.1 1.4 Self-inflicted injuries 0.5 0.9 1.3 Other intentional injuries 0.3 0.2 0.1
  • 12. Results - Attributable cause contributions Males 5 Contribution to life expectancy difference (years) 4 3 2 1.9 1.7 1.5 1 0.9 0.7 0.5 0.2 0.1 0.1 0 1989-1993 1994-1998 1999-2003 Smoking Alcohol Amenable November 24, 2009 12/19
  • 13. Results - Attributable cause contributions Females 5 Contribution to life expectancy difference (years) 4.0 4.1 4 3.6 3 2 1.7 1.0 1 0.6 0.2 0.2 0.3 0 1989-1993 1994-1998 1999-2003 Smoking Alcohol Amenable November 24, 2009 13/19
  • 14. Contribution to difference in life expectancy (%) November 24, 2009 -5 0 5 10 15 20 <1 Results 1-4 5-9 10-14 15-19 20-24 25-29 1991 30-34 35-39 1996 40-44 45-49 Age group 2001 50-54 55-59 60-64 65-69 70-74 75-79 80-84 85-89 90+ - Age contributions (males, percent) 14/19
  • 15. Contribution to difference in life expectancy (%) November 24, 2009 -5 0 5 10 15 20 <1 Results 1-4 5-9 10-14 15-19 20-24 25-29 1991 30-34 35-39 1996 40-44 45-49 Age group 2001 50-54 55-59 60-64 65-69 70-74 75-79 80-84 85-89 90+ 15/19 - Age contributions (females, percent)
  • 16. Discussion  Life expectancy difference appears to be increasing between Inuit Nunangat & Canada  Difference is related to specific causes of death • Males – injury & suicide are major contributors  Injury and suicide account for 7.5 years of difference • Females – chronic diseases are major contributors  Lung cancer and COPD account for 4 years of difference  Specific causes differ between sexes • Smoking-related diseases for females • Alcohol-related diseases are not major contributors November 24, 2009 16/19
  • 17. Discussion  Difference is concentrated in specific age groups • Males – mortality between 15 and 29 is key  1/3 of difference due to mortality between 15 and 29 years  This is largely due to injury and suicide • Females – mortality after age 60 contributes most  50% of difference due to mortality after 60 years of age  This is largely due to chronic diseases November 24, 2009 17/19
  • 18. Limitations  Limits to geographic approach • For all residents of Inuit Nunangat, not just Inuit • Unequal access to health services • Older population may move “south” for care  Reliability of vital statistics • Cause of death coding may vary between periods  Use of a comparable population • Comparison to other isolated communities, other Aboriginal groups, or other countries November 24, 2009 18/19
  • 19. Acknowledgements  Contact: • Paul A. Peters, PhD Health Analysis Division Statistics Canada Ottawa, ON (613) 951-0616 paul.a.peters@statcan.gc.ca  Thanks to: Health Canada FNIHB (Jennifer Pennock, Neil Goedhuis) November 24, 2009 19/19