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Predictive case modelling
 in social care and health


   Geraint Lewis FRCP FFPH
                     www.nuffieldtrust.org.uk
The Nuffield Trust




t: 020 7631 8450
e: info@nuffieldtrust.org.uk
www.nuffieldtrust.org.uk
Case Finding
• NHS predictive models
• Models for social care
Evaluation
Remuneration
Why Predictive Modelling?
  • BMJ in paper* in 2002 showed Kaiser Permanente in
    California seemed to provide higher quality healthcare
    than the NHS at a lower cost
             *Getting more for their dollar: a comparison of the NHS with California's Kaiser Permanente BMJ 2002;324:135-143




  • Kaiser identify high risk people in their population and
    manage them intensively to avoid admissions


  • Inaccurate Approaches:
     – Clinician referrals
     – Threshold approach (e.g. all patients aged >65 with 2+
       admissions)
Frequently-admitted patients
                                       50
Average number of emergency bed days



                                       45


                                       40


                                       35


                                       30


                                       25


                                       20


                                       15


                                       10


                                       5


                                       0
                                        -5   -4   -3   -2   -1   Intense   +1   +2   +3   +4
                                                                   year
Regression to the mean
Average number of emergency bed days

                                       50


                                       45



                                       40


                                       35


                                       30


                                       25



                                       20


                                       15


                                       10


                                       5



                                       0
                                                                 Intense
                                        -5   -4   -3   -2   -1     year    +1   +2   +3   +4
Emerging Risk
                                       50


                                       45
Average number of emergency bed days




                                       40


                                       35


                                       30


                                       25


                                       20


                                       15


                                       10


                                       5


                                       0

                                           -5   -4   -3   -2   -1             +1   +2   +3   +4
                                                                    Intense
                                                                      year
Kaiser Pyramid
                                                                   Small numbers of
                                                                  people at very high
                                                                          risk

The Pyramid
represents the
distribution of
risk across the
population

                                                                          Large numbers
                                                                           of people at
                                                                             low risk




                  [Size of shape is proportional to number of patients]
Patterns in routine data

    Inpatient
    Inpatient   A&E data
                A&E data      GP Practice
                              GP Practice
      data
       data                      data
                                 data




 Outpatient
 Outpatient
   data
    data             PARR
                   Combined
                    Model


  Census
  Census
   data
   data
Scotland      Wales
• SPARRA      • PRISM model
• SPARRA-MD   • Welsh Predictive Risk
                Service
Name, Address, DOB   131178      J7KA42
                                                                      Encrypted,
                                                                      linked data
                                                         Inpatient
                                                         Inpatient
Name, Address, DOB   131178      J7KA42
                                                         Outpatient
                                                         Outpatient
                                                J7KA42
                                                         A&E
                                                         A&E
Name, Address, DOB   131178      J7KA42

                                                         GP
                                                         GP

Name, Address, DOB   131178      J7KA42




                                                          J7KA42   76.4




                                                          131178   76.4

                              Decrypted data
                              with risk score
                                 attached
10 Million Patient-Years
                           10 Million Patient-Years
                                    of Data
                                    of Data




Development                                           Validation
 5 Million Patient-Years
 5 Million Patient-Years                              5 Million Patient-Years
                                                      5 Million Patient-Years
         of Data
          of Data                                             of Data
                                                               of Data
Inpatient
    Inpatient
    Outpatient
    Outpatient     Development
    A&E
    A&E
    GP
                     Sample
    GP

J7KA42             J7KA42             J7KA42



YH8TPP             YH8TPP             YH8TPP



G8HE9F             G8HE9F             G8HE9F



3LWZ67             3LWZ67             3LWZ67



2NX632             2NX632             2NX632



LG5DSD             LG5DSD             LG5DSD



3V9D54R            3V9D54R            3V9D54R




          Year 1             Year 2             Year 3
Inpatient
   Inpatient
   Outpatient
   Outpatient      Development
   A&E
   A&E
   GP
                     Sample
   GP

J7KA42             J7KA42             J7KA42



YH8TPP             YH8TPP             YH8TPP



G8HE9F             G8HE9F             G8HE9F



3LWZ67             3LWZ67             3LWZ67



2NX632             2NX632             2NX632



LG5DSD             LG5DSD             LG5DSD



3V9D54R            3V9D54R            3V9D54R




          Year 1             Year 2             Year 3
Inpatient
   Inpatient
   Outpatient
                   Development
   Outpatient
   A&E
   A&E               Sample
   GP
   GP

J7KA42             J7KA42             J7KA42



YH8TPP             YH8TPP             YH8TPP



G8HE9F             G8HE9F             G8HE9F



3LWZ67             3LWZ67             3LWZ67



2NX632             2NX632             2NX632



LG5DSD             LG5DSD             LG5DSD



3V9D54R            3V9D54R            3V9D54R




          Year 1             Year 2             Year 3
Inpatient
   Inpatient
   Outpatient
                    Validation
   Outpatient
   A&E
   A&E               Sample                               True
                                                           False
                                                         Positive
                                                         Negative
   GP
   GP

A89KP5            A89KP5                       A89KP5



833TY6            833TY6                       833TY6



I9QA44            I9QA44                       I9QA44



85H3D             85H3D                        85H3D



6445JX            6445JX                       6445JX



233UMB            233UMB                       233UMB
                                                            False
                                                           Positive
RF02UH            RF02UH                       RF02UH
                                     True
                                    Negative

         Year 1            Year 2                       Year 3
Inpatient
   Inpatient
   Outpatient
   Outpatient
                     Using the Model
   A&E
   A&E
   GP
   GP

A89KP5                 A89KP5



833TY6                  833TY6



I9QA44                  I9QA44



85H3D                   85H3D



6445JX                  6445JX



233UMB                 233UMB



RF02UH                 RF02UH




         Last Year               This Year   Next Year
Distribution of Future Utilisation

                                  £4,500
Actual Average cost per patient




                                  £4,000


                                  £3,500


                                  £3,000


                                  £2,500


                                  £2,000


                                  £1,500


                                  £1,000


                                   £500


                                     £0
                                           0   10   20      30     40     50     60      70   80   90

                                                         Predicted Risk (centile rank)
NHS Combined Model
Clinical Profiles
Tackling the Inverse Care Law
Developing Business Cases
How the output of predictive
     models are used
                      •   Case Management


                      •   Intensive Disease Management


                      •   Less Intensive Disease
                          Management

                      •   Wellness Programmes



            Potential Misuses
                      Dumping

                      Cream-skimming

                      Skimping
Health Needs                        Social Care Needs
           •   Diagnoses                         •   Client group
           •   Prescriptions                     •   Disabilities
           •   Record of Health                  •   Record of care
               Contacts                              history



PAST                              Predictive
                                    Model
FUTURE



         Health Service Use                     Social Care Use
           •   GP visits                         •   Residential care
           •   Community care                    •   Intensive home
           •   Hospital care                         care
                                                 •   Direct payments
Evaluation of Preventive Care


                    5
Overcoming regression to the
mean using a control group (1)

                       Start of intervention
Overcoming regression to the
mean using a control group (2)

                       Start of intervention
Overcoming regression to the
mean using a control group
(3)
                      Start of intervention
Overcoming regression to the
mean using a control group (4)

                       Start of intervention
Person-Based Resource Allocation
• Historically, GP practice budgets set on area-
  based variables
• New approach is person-based
• Exclude certain variables to avoid perverse
  incentives
  – Procedures
  – Disease severity
geraint.lewis@nuffieldtrust.org.uk



                                    t: 020 7631 8450
                          e: info@nuffieldtrust.org.uk
Trend

 Model
predicts:



 Details




Examples
Trend

 Model
                 Cost
predicts:



 Details    Model predicts
            which patients
            will become
            high-cost over
            next 6 or 12
            months


Examples    Low-cost
            patient this
            year will
            become high-
            cost next year
Trend

 Model
                 Cost             Event
predicts:



 Details    Model predicts   Model predicts
            which patients   which patients
            will become      will have an
            high-cost over   event that can
            next 6 or 12     be avoided
            months


Examples    Low-cost         Patient will be
            patient this     hospitalized
            year will
            become high-     Patient will
            cost next year   have diabetic
                             ketoacidosis
Trend

 Model
                 Cost             Event         Actionability
predicts:



 Details    Model predicts   Model predicts    Model predicts
            which patients   which patients    which patients
            will become      will have an      have features
            high-cost over   event that can    that can readily
            next 6 or 12     be avoided        be changed
            months


Examples    Low-cost         Patient will be   Patient has
            patient this     hospitalized      angina but is
            year will                          not taking
            become high-     Patient will      aspirin
            cost next year   have diabetic     Patient does
                             ketoacidosis      not have
                                               pancreatic
                                               cancer
                                               (Ambulatory
                                               Care Sensitive)
Trend

 Model
                 Cost             Event         Actionability      Readiness to
predicts:                                                            engage




 Details    Model predicts   Model predicts    Model predicts     Model predicts
            which patients   which patients    which patients     which patients
            will become      will have an      have features      are most likely
            high-cost over   event that can    that can readily   to engage in
            next 6 or 12     be avoided        be changed         upstream care
            months


Examples    Low-cost         Patient will be   Patient has        Patient does
            patient this     hospitalized      angina but is      not abuse
            year will                          not taking         alcohol
            become high-     Patient will      aspirin
            cost next year   have diabetic     Patient does       Patient has no
                             ketoacidosis      not have           mental illness
                                               pancreatic
                                               cancer
                                               (Ambulatory        Patient
                                               Care Sensitive)    previously
                                                                  compliant
Trend

 Model
                 Cost             Event         Actionability      Readiness to       Receptivity
predicts:                                                            engage




 Details    Model predicts   Model predicts    Model predicts     Model predicts    Model predicts
            which patients   which patients    which patients     which patients    what mode and
            will become      will have an      have features      are most likely   form of
            high-cost over   event that can    that can readily   to engage in      intervention
            next 6 or 12     be avoided        be changed         upstream care     will be most
            months                                                                  successful for
                                                                                    each patient

Examples    Low-cost         Patient will be   Patient has        Patient does      Patient prefers
            patient this     hospitalized      angina but is      not abuse         email rather
            year will                          not taking         alcohol           than telephone
            become high-     Patient will      aspirin
            cost next year   have diabetic     Patient does       Patient has no    Patient prefers
                             ketoacidosis      not have           mental illness    male voice
                                               pancreatic                           rather than
                                               cancer                               female
                                               (Ambulatory        Patient
                                               Care Sensitive)    previously
                                                                  compliant         Readiness to
                                                                                    change

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Geraint Lewis Ageing Well presentation

  • 1. Predictive case modelling in social care and health Geraint Lewis FRCP FFPH www.nuffieldtrust.org.uk
  • 2. The Nuffield Trust t: 020 7631 8450 e: info@nuffieldtrust.org.uk www.nuffieldtrust.org.uk
  • 3. Case Finding • NHS predictive models • Models for social care Evaluation Remuneration
  • 4. Why Predictive Modelling? • BMJ in paper* in 2002 showed Kaiser Permanente in California seemed to provide higher quality healthcare than the NHS at a lower cost *Getting more for their dollar: a comparison of the NHS with California's Kaiser Permanente BMJ 2002;324:135-143 • Kaiser identify high risk people in their population and manage them intensively to avoid admissions • Inaccurate Approaches: – Clinician referrals – Threshold approach (e.g. all patients aged >65 with 2+ admissions)
  • 5. Frequently-admitted patients 50 Average number of emergency bed days 45 40 35 30 25 20 15 10 5 0 -5 -4 -3 -2 -1 Intense +1 +2 +3 +4 year
  • 6. Regression to the mean Average number of emergency bed days 50 45 40 35 30 25 20 15 10 5 0 Intense -5 -4 -3 -2 -1 year +1 +2 +3 +4
  • 7. Emerging Risk 50 45 Average number of emergency bed days 40 35 30 25 20 15 10 5 0 -5 -4 -3 -2 -1 +1 +2 +3 +4 Intense year
  • 8. Kaiser Pyramid Small numbers of people at very high risk The Pyramid represents the distribution of risk across the population Large numbers of people at low risk [Size of shape is proportional to number of patients]
  • 9. Patterns in routine data Inpatient Inpatient A&E data A&E data GP Practice GP Practice data data data data Outpatient Outpatient data data PARR Combined Model Census Census data data
  • 10. Scotland Wales • SPARRA • PRISM model • SPARRA-MD • Welsh Predictive Risk Service
  • 11. Name, Address, DOB 131178 J7KA42 Encrypted, linked data Inpatient Inpatient Name, Address, DOB 131178 J7KA42 Outpatient Outpatient J7KA42 A&E A&E Name, Address, DOB 131178 J7KA42 GP GP Name, Address, DOB 131178 J7KA42 J7KA42 76.4 131178 76.4 Decrypted data with risk score attached
  • 12. 10 Million Patient-Years 10 Million Patient-Years of Data of Data Development Validation 5 Million Patient-Years 5 Million Patient-Years 5 Million Patient-Years 5 Million Patient-Years of Data of Data of Data of Data
  • 13. Inpatient Inpatient Outpatient Outpatient Development A&E A&E GP Sample GP J7KA42 J7KA42 J7KA42 YH8TPP YH8TPP YH8TPP G8HE9F G8HE9F G8HE9F 3LWZ67 3LWZ67 3LWZ67 2NX632 2NX632 2NX632 LG5DSD LG5DSD LG5DSD 3V9D54R 3V9D54R 3V9D54R Year 1 Year 2 Year 3
  • 14. Inpatient Inpatient Outpatient Outpatient Development A&E A&E GP Sample GP J7KA42 J7KA42 J7KA42 YH8TPP YH8TPP YH8TPP G8HE9F G8HE9F G8HE9F 3LWZ67 3LWZ67 3LWZ67 2NX632 2NX632 2NX632 LG5DSD LG5DSD LG5DSD 3V9D54R 3V9D54R 3V9D54R Year 1 Year 2 Year 3
  • 15. Inpatient Inpatient Outpatient Development Outpatient A&E A&E Sample GP GP J7KA42 J7KA42 J7KA42 YH8TPP YH8TPP YH8TPP G8HE9F G8HE9F G8HE9F 3LWZ67 3LWZ67 3LWZ67 2NX632 2NX632 2NX632 LG5DSD LG5DSD LG5DSD 3V9D54R 3V9D54R 3V9D54R Year 1 Year 2 Year 3
  • 16. Inpatient Inpatient Outpatient Validation Outpatient A&E A&E Sample True False Positive Negative GP GP A89KP5 A89KP5 A89KP5 833TY6 833TY6 833TY6 I9QA44 I9QA44 I9QA44 85H3D 85H3D 85H3D 6445JX 6445JX 6445JX 233UMB 233UMB 233UMB False Positive RF02UH RF02UH RF02UH True Negative Year 1 Year 2 Year 3
  • 17. Inpatient Inpatient Outpatient Outpatient Using the Model A&E A&E GP GP A89KP5 A89KP5 833TY6 833TY6 I9QA44 I9QA44 85H3D 85H3D 6445JX 6445JX 233UMB 233UMB RF02UH RF02UH Last Year This Year Next Year
  • 18. Distribution of Future Utilisation £4,500 Actual Average cost per patient £4,000 £3,500 £3,000 £2,500 £2,000 £1,500 £1,000 £500 £0 0 10 20 30 40 50 60 70 80 90 Predicted Risk (centile rank)
  • 23. How the output of predictive models are used • Case Management • Intensive Disease Management • Less Intensive Disease Management • Wellness Programmes Potential Misuses Dumping Cream-skimming Skimping
  • 24. Health Needs Social Care Needs • Diagnoses • Client group • Prescriptions • Disabilities • Record of Health • Record of care Contacts history PAST Predictive Model FUTURE Health Service Use Social Care Use • GP visits • Residential care • Community care • Intensive home • Hospital care care • Direct payments
  • 25.
  • 26.
  • 28. Overcoming regression to the mean using a control group (1) Start of intervention
  • 29. Overcoming regression to the mean using a control group (2) Start of intervention
  • 30. Overcoming regression to the mean using a control group (3) Start of intervention
  • 31. Overcoming regression to the mean using a control group (4) Start of intervention
  • 32. Person-Based Resource Allocation • Historically, GP practice budgets set on area- based variables • New approach is person-based • Exclude certain variables to avoid perverse incentives – Procedures – Disease severity
  • 33. geraint.lewis@nuffieldtrust.org.uk t: 020 7631 8450 e: info@nuffieldtrust.org.uk
  • 35. Trend Model Cost predicts: Details Model predicts which patients will become high-cost over next 6 or 12 months Examples Low-cost patient this year will become high- cost next year
  • 36. Trend Model Cost Event predicts: Details Model predicts Model predicts which patients which patients will become will have an high-cost over event that can next 6 or 12 be avoided months Examples Low-cost Patient will be patient this hospitalized year will become high- Patient will cost next year have diabetic ketoacidosis
  • 37. Trend Model Cost Event Actionability predicts: Details Model predicts Model predicts Model predicts which patients which patients which patients will become will have an have features high-cost over event that can that can readily next 6 or 12 be avoided be changed months Examples Low-cost Patient will be Patient has patient this hospitalized angina but is year will not taking become high- Patient will aspirin cost next year have diabetic Patient does ketoacidosis not have pancreatic cancer (Ambulatory Care Sensitive)
  • 38. Trend Model Cost Event Actionability Readiness to predicts: engage Details Model predicts Model predicts Model predicts Model predicts which patients which patients which patients which patients will become will have an have features are most likely high-cost over event that can that can readily to engage in next 6 or 12 be avoided be changed upstream care months Examples Low-cost Patient will be Patient has Patient does patient this hospitalized angina but is not abuse year will not taking alcohol become high- Patient will aspirin cost next year have diabetic Patient does Patient has no ketoacidosis not have mental illness pancreatic cancer (Ambulatory Patient Care Sensitive) previously compliant
  • 39. Trend Model Cost Event Actionability Readiness to Receptivity predicts: engage Details Model predicts Model predicts Model predicts Model predicts Model predicts which patients which patients which patients which patients what mode and will become will have an have features are most likely form of high-cost over event that can that can readily to engage in intervention next 6 or 12 be avoided be changed upstream care will be most months successful for each patient Examples Low-cost Patient will be Patient has Patient does Patient prefers patient this hospitalized angina but is not abuse email rather year will not taking alcohol than telephone become high- Patient will aspirin cost next year have diabetic Patient does Patient has no Patient prefers ketoacidosis not have mental illness male voice pancreatic rather than cancer female (Ambulatory Patient Care Sensitive) previously compliant Readiness to change