How Data and AI is transforming Pharma. Value of Data How Data and AI can transform each and every functions How organizations should approach the data and AI What should be the data strategy What is the future post Covid19

1. “data is the new oil;”
for large Pharma and Bio-Pharma,
data is the new potential
blockbuster

2. 2
Agenda
Co-create for a better future
Importance & Value of Data
in Pharma
Contextualizing Pharma Data
What Organizations need to do
Gold Standard of Evidence
and Drivers
Data and AI in Pharma
01.
02.
03.
04.
06.
07.
08.
09.
Data challenges in Clinical
The Data Strategy
05. 10.
Platform approach
2020 – STEFANINI GROUP | PRESENTATION
Q&A
Message for the Furture

3. 3
• The McKinsey Global Institute estimates that applying
big-data strategies to better inform decision making
could generate up to $100 billion in value annually across
the US health-care system.
• The Smart Pill:
• Optimizing Functions.
• Increased collaborations- Pharma, Payers, Providers,
Physicians, Partners.
Value of Data
2020 – STEFANINI GROUP | PRESENTATION

4. Volume, Velocity, Variety
CONTEXTUALIZING DATA IN PHARMA
1 Trial including Genomic Data is 1 Petabyte of Data
Omics
Preclinical &
Drug Discovery
Clinical
SCM
Marketing & Patient
Genomics & Proteomics
HTS, Leads, Drug Target
Interactions
Trial Data
Supply Chain and
Manufacturing Systems, IoT,
Sensors
Marketing, Patient
engagement, sentiment,
social media, IoMT, Devices.
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2020 – STEFANINI GROUP | PRESENTATION

5. GOLD STANDARD OF EVIDENCE & DRIVERS
Explosion of Data and Digital Technologies.
1
2
3
Generation ->
Clinical Trials
Generation ->
Digitization of
Healthcare- Claims,
EMR data- RWE
Generation->
Patient data from
wearables,
digital pills,
devices, IoMT.
4th Gen Post Covid19-
Smart & Virtual Trials,
Patient Outcomes
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2020 – STEFANINI GROUP | PRESENTATION

6. WHAT ORGANIZATIONS NEED TO DO
Mindset & Culture Network CollaborateFunction CoE
Organization, Senior
Management and every
functions leadership to
be Digital and Data
mindset.
Create key functions
CoE around Data and AI
like: Omics, Preclinical
& Discovery, Clinical
Build a strong
ecosystem with
Partners, Startups,
Academia.
Eg: Merck with Inst of
Systems Biology, Takeda
& MIT, Novartis Biome
More with Customers-
Providers, Payers,
Physicians, Partners.
Value based contracting
with Payers, focused on
outcomes.
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2020 – STEFANINI GROUP | PRESENTATION

7. DATA STRATEGY
Organization & Governance
Define ownership, accountability. Define
standards and policies.
Business Goals Alignment
Have alignment with business goals, functions
goals.
Risk & Compliance
Invest in GRC tools, technologies. Have
policies & procedures.
Proprietary Data
Identify propriety data, its value and have
processes policies to protect and gain value
from propriety data.
Data Quality
Ensure data quality, get rid of redundancies,
establish quality processes.
Architecture & Roadmap
Aligned to organization, business and
functions goals. Eg. Any function or TA
should be able to implement AI.
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2020 – STEFANINI GROUP | PRESENTATION

8. DATA & AI IN PHARMA
In-silico preclinical testing
In-silico animal models for preclinical
testing. Automate manipulation,
analysis, cell selection.
In-silico, Digital Trials
In-silico clinical models, smart
trials, virtual trials.
Personalized Medicine
Trained AI models on
genotype, phenotype
information, behavior
patterns.
In-silico Drug Discovery
Computational, drug design and
discovery. AI on large data sets to
identify leads, targets.
Diagnosis
Automate medical image screening
with trained AI models.
Genotype–Phenotype
Identification
Smart SCM
Industry 4.0
Data from IoT, Factory Sensors,
SC. Mfg based on real time
consumption data. Robots.
Train AI for smart routes 8
2020 – STEFANINI GROUP | PRESENTATION

9. 9DATA CHALLENGES IN CLINICAL
Multiple Systems,
Products, Vendors.
Many manual
processes resulting in
increased errors..
Increased time, cost
and efforts.
Complex environment
affecting the
collaboration and data
flow, data access,
analytics and reporting.
Disparate ComplexManual Low RoI
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2020 – STEFANINI GROUP | PRESENTATION

10. 10
Study Building Provisioning Smart Trials Decentralized Trials
A Digital Study Design &
Data Flow Solution
Above and beyond
traditional marketing by
promoting
environmental.
Device Provisioning with
an innovative Solution
with AI
Above and beyond
traditional marketing by
promoting
environmental.
Platform with eDC, eCOA,
eICF, Coder, IRT and CTMS
modules, in a unified
comprehensive platform
Above and beyond
traditional marketing by
promoting
environmental.
Above and beyond
traditional marketing by
promoting
environmental.
Platform Approach
Platform for Clinical Transformation
Integrates Automates Predicts Resolves Insights
Integrates with all
systems, devices and
applications. Provides
Support
Automates
Processes,
equipment's
Predicts issues &
alerts
Initiates solutions &
maintenance
Gives insights &
answers on all the
data
Virtual Trials: Patient data
can be collected anywhere,
site, home, remote.
Increased engagement,
retention & satisfaction
2020 – STEFANINI GROUP | PRESENTATION
10

11. 11MESSAGE FOR THE FUTURE
DATA CULTURE
Organizations should have a data mindset and culture, it’s the
most valuable asset.
PATIENT FIRST
Should focus on outcomes, patient care and wellness.
DIGITAL
Should try to become digital, paper less with increased automation.
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2
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4P
Collaboration- Payers, Providers, Physicians, Partners.4
2020 – STEFANINI GROUP | PRESENTATION

12. 12
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2020 – STEFANINI GROUP | PRESENTATION

13. 2020 – STEFANINI GROUP | PRESENTATION
Nagesh Jadhav
Director Digital Transformation &
Innovation, Life sciences
Nagesh.Jadhav@stefanini.com
Denis Rynders
Global Business Unit Leader,
Digital Health Services
Denis.Reynders@stefanini.com
Thank You!!