Pathology (atherosclerosis)

1. Pathology practical 1
(Atherosclerosis)
By : Osama Al-Zahrani
@OSAMA_Z96

2. Capillary Hemangioma

3. Diagnosis :
(Capillary Hemangioma).
Comment :
- Multiple dilated vascular channels
(VCs) lined by attenuated
endothelium.
- The lumen contain blood elements
mainly RBCS.
- VCs are separated by intervening
stroma.
- Inflammatory cells are seen in
intervening stroma.Dilated VCs
Attenuated
endothelium
Intervening stroma
and inflammatory cells
RBCs

4. Cavernous lymphgioma

5. Diagnosis :
(Cavernous lymphgioma).
Comment :
- Multiple dilated lymphatic channels
(LCs) lined by attenuated endothelium.
- The lumen contain lymph and
inflammatory cells.
- LCs are separated by intervening
stroma
- Inflammatory cells are also seen in
intervening stroma.
Lymph
Inflammatory cells
Stroma
Lymphatic channel
Lymphatic channel

6. Hemangioendothelioma

7. Diagnosis :
(Hemangioendothelioma).
Comment :
- Nodules of epitheloid cells separated by
fibromyxoid stroma.
- Epithelioid cells are rounded with eosinophilic
cytoplasm, mild to moderately atypical nuclei with
prominent nucleoli and no /rare mitotic figures.
- Epithelioid and fibromyxoid tumor cells have
focal intracytoplasmic vacuoles containing red
blood cells embedded in fibromyxoid matrix
Nodule
Fibromyxoid matrix
Intracytoplasmic
vacuoles
Epitheloid cells

8. Kaposi Sarcoma

9. Diagnosis :
(Kaposi Sarcoma).
Comment :
- A cellular dermal nodule comprised of a spindle
cell proliferation forming slit-like vascular
spaces.
- Intra and extra cellular hyaline globules are
present, though to represent engulphed
erythrocytes.
- Erythrocytes (RBCs) are seen within the slit like
spaces and throughout the tumor.
Slit-like vascular spaces
Fascicles of spindle shaped cells