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Potent plants
for
Hypothyroidism
(Part – II)
Presented by
Dr. Sudhakar Kokate
Director PPRC, India
Allopathic medications
 Levothroid
 Levoxyl
 Synthroid
PPRC/INDIA 01
 Cytomel
 Euthroid
 Thyrolar
Side effects
PPRC/INDIA 02
 Tremors
 Nervousness
 Heart palpitation
 Too much weight loss
 Bone thinning
 Frequent bowel movements
Scientific investigations
PPRC/INDIA 03
Scientific investigations on thyroid dependent respiration,
cardiovascular system, digestion neural regulation and
reproduction
 Investigations were started few years back
 Herbal regulation of thyroid function is recent concept and
acquiring attention of scientists worldwide
Scientific investigations
PPRC/INDIA 04
 Commercial Ayurvedic drugs are also available in market
due to intense efforts of scientists
 Research work on possible mode of action of plants is in
progress
 Different plant products appears to be different in different
plant extracts
Scientific investigations
PPRC/INDIA 05
 Dose dependent activity is observed in experiments about
thyroid-plant relationship
 In general herbal products are safe
 Some plant extracts in combination with other improve
quality
 Standardization of dose and duration needed
Plant derived drugs for hypothyroidism
PPRC/INDIA 06
 Suddha guggulu
 Kanchnar guggulu
 Gayatrin
 Kelp
 Ginseng
 Wulong dan
 Fuschen decoction
 Liv. 52
Achyranthes aspera
PPRC/INDIA 07
Achyranthes aspera
PPRC/INDIA 08
 Dose: 200 mg / kg
 Days treated: 7
 Ref: Tahiliani and Kar 2000
Bacopa monnieri
PPRC/INDIA 09
Bacopa monnieri
PPRC/INDIA 10
 Dose: 200 mg / kg
 Days treated: 15
 Ref: Kar et. al. 2002
Bauhinia variegata
PPRC/INDIA 11
Bauhinia variegata
PPRC/INDIA 12
 Dose: 200 mg / kg
 Days treated: 20
 Ref: Veena et. al. 1975
Bauhinia purpurea
PPRC/INDIA 13
Bauhinia purpurea
PPRC/INDIA 14
 Dose: 2.5 mg / kg
 Days treated: 20
 Ref: Panda and Kar 1999, 2000
Commiphora mukul
PPRC/INDIA 15
Commiphora mukul
PPRC/INDIA 16
 Dose: 200 mg / kg
 Days treated: 15
 Ref: Panda and Kar 1998
Veena et. al. 1975
Eichorina crassipes
PPRC/INDIA 17
Eichorina crassipes
PPRC/INDIA 18
 Dose: 200 mg / kg
 Days treated: 20
 Ref: Veena et. al. 1975
Inula racemosa
PPRC/INDIA 19
Inula racemosa
PPRC/INDIA 20
 Dose: 400 mg / kg
 Days treated: 21
 Ref: Tripathi and Chaturvedi 1995
Momordica charantia
PPRC/INDIA 21
Momordica charantia
PPRC/INDIA 22
 Dose: 200 mg / kg
 Days treated: 15
 Ref: Panda and Kar 2000
Piper betle
PPRC/INDIA 23
Piper betle
PPRC/INDIA 24
 Dose: 400 mg / kg
 Days treated: 15
 Ref: Panda and Kar 2000
Sida cordifolia
PPRC/INDIA 25
Sida cordifolia
PPRC/INDIA 26
 Dose: 100 mg / kg
 Days treated: 15
 Ref: Tahiliani and Kar 2001
Saussurea lappa
PPRC/INDIA 27
Saussurea lappa
PPRC/INDIA 28
 Dose: 400 mg / kg
 Days treated: 14
 Ref: Chaturvedi et. al. 1993
Withania somnifera
PPRC/INDIA 29
Withania somnifera
PPRC/INDIA 30
 Dose: 1400 mg / kg
 Days treated: 30
 Ref: Panda and Kar 1998, 1999
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Hypothyroidism - II