PRAFUL KAMBLE
1 SlideShare 1 Abonnés
Personal Information
Entreprise/Lieu de travail
São Paulo Area, Brazil Brazil
Profession
PhD student at UFABC
Secteur d’activité
Education
À propos
In pursuit of Post Doctoral Position in Neurodegenerative disease Currently I am pursuing my PhD in Neuroscience and Cognition from Federal University of ABC, Brazil. I will defend my PhD thesis in September 2015, titled "Role of NF-kBs activator and inhibitor in modulation of BAG2 promoted p-Tau degradation in Alzheimer's disease"​. My project was based on the role of TLR3 and TLR4 and its signaling cascade in modulating BAG2 associated phospho-tau degradation in SH-SY5y cells. More specifically, stimulating TLR3 and TLR4 with pIpC and LPS respectively, and studying the molecular mechanism associated with phospho-tau degradation with respect to BAG2 overexpression. Molecular and cellula.
Coordonnées
Mots-clés
alzheimer's disease tau
Tout plus

Présentations

(1)

Published animated redox and antioxidant mechanisms

il y a 9 ans • 505 Vues
Personal Information
Entreprise/Lieu de travail
São Paulo Area, Brazil Brazil
Profession
PhD student at UFABC
Secteur d’activité
Education
À propos
In pursuit of Post Doctoral Position in Neurodegenerative disease Currently I am pursuing my PhD in Neuroscience and Cognition from Federal University of ABC, Brazil. I will defend my PhD thesis in September 2015, titled "Role of NF-kBs activator and inhibitor in modulation of BAG2 promoted p-Tau degradation in Alzheimer's disease"​. My project was based on the role of TLR3 and TLR4 and its signaling cascade in modulating BAG2 associated phospho-tau degradation in SH-SY5y cells. More specifically, stimulating TLR3 and TLR4 with pIpC and LPS respectively, and studying the molecular mechanism associated with phospho-tau degradation with respect to BAG2 overexpression. Molecular and cellula.
Mots-clés
alzheimer's disease tau
Tout plus