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NAME -PRIYAM NATH
3rd SEMESTER
017
SCHISTOSOMA
-an insight
INTRODUCTION
 Schistosoma is the only trematode that invades through the skin.
 Five species of schistomes infect humans
 Schistosome haematobium causes urinary tract disease the other species
causes intestinal disease
 GEOGRAPHIC DISTRIBUTION
 Schistosoma haematobium-Africa, some in Middle East, Turkey, and India
 Schistosoma mansoni-Africa and America
 Schistosoma japonicum-Far east Asia, Some parts of Africa
 Schistosoma mekongi- Southeast Asia
 Schistosoma intercalatum- central and west Africa
EPIDEMIOLOGY AND MORPHOLOGY
 Approximately 250 million people are infected with schistosomes and
600 million people are at risk
 Adult worms are 10 to 20mm long
 Schistosomes have separate sexes
 The male has a canal in which the slender female worm resides
THE EGG
 Eggs penetrate the intestinal or bladder mucosa and are passed in
stool or urine
 Other eggs remain within the host organ or are transported through the
portal system to the liver
 Excreted eggs hatch in freshwater, releasing miracidia, the first larval
stage
 Miracidia enters snails
THE CERCARIE
 Infective stage
 Cercarie penetrate human skin within a few minutes after exposure
 When they penetrate they lose their forked tail and transform into schistosomula
 Schistosomula mature and reach mesentric veins(S.mansonii, S.japonicum. )
,bladder vessels (S.haematobium)where they live and ovulate for duration of
hosts life
ADULT WORM
Schistosoma mansoni Schistosoma japonicum
INTERMEDIATE HOST
 Schistosoma haematobolium-
Bulinus truncatus
 Schistosoma mansoni-
Biomphalaria alexandria
 Schistosomia japonicum-
Oncomelania sp.
 Schistosomia mekongi-
Neotricula aperta
LIFE CYCLE
SCHISTOSOMA COUPLE
Schistosoma japonicumSchistosoma mansoni
PERIOD OF COMMUNICABILITY
 Life span-5to 10 years, so infected human can excrete eggs up to 10 years
 An infected snail can release cercarie from several weeks to 3 months of its life
 An infected snail can lay eggs 300-3000/day
SCHISTOSOMIASIS
 SCHISTOSOMIASIS OR BILHARZIA
 Disease affecting many people in developing countries.
 ‘Acute schistosomiasis'- snail fever and cutaneous schistosomiasis
 Low mortality rate, schistosomiasis can also be very debilitating
 Bilharzia or bilharziosis, named after Theodor Bilharz, who first described the
cause of urinary schistosomiasis in 1851.
SYMPTOMS
 Hepatosplenomegaly
 Muscle atrophy
 Anaemia
 Diarrhea
 Haemorrhage from the gastrointestinal tract
DIAGNOSTIC STAGE
 Schistosoma haematobolium
 Eggs found in urine of urinary Schistosomiasis patients
 Oval egg with terminal spine
 Schistosoma mansoni
 Eggs found in stool of intestinal Schistosomiasis patients
 Oval egg with lateral spine
MANAGEMENT
 Contaminated water should be avoided
 Sanitary disposal of sewage
 Prevent contamination of water by feces and urine
 Destruction of snails
 Treat the patients
 No vaccine is available
 Praziquantel is effective against all species
Thank youThank u…

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Schistosoma- an insight by Priyam Nath

  • 1. NAME -PRIYAM NATH 3rd SEMESTER 017 SCHISTOSOMA -an insight
  • 2. INTRODUCTION  Schistosoma is the only trematode that invades through the skin.  Five species of schistomes infect humans  Schistosome haematobium causes urinary tract disease the other species causes intestinal disease  GEOGRAPHIC DISTRIBUTION  Schistosoma haematobium-Africa, some in Middle East, Turkey, and India  Schistosoma mansoni-Africa and America  Schistosoma japonicum-Far east Asia, Some parts of Africa  Schistosoma mekongi- Southeast Asia  Schistosoma intercalatum- central and west Africa
  • 3. EPIDEMIOLOGY AND MORPHOLOGY  Approximately 250 million people are infected with schistosomes and 600 million people are at risk  Adult worms are 10 to 20mm long  Schistosomes have separate sexes  The male has a canal in which the slender female worm resides
  • 4. THE EGG  Eggs penetrate the intestinal or bladder mucosa and are passed in stool or urine  Other eggs remain within the host organ or are transported through the portal system to the liver  Excreted eggs hatch in freshwater, releasing miracidia, the first larval stage  Miracidia enters snails
  • 5. THE CERCARIE  Infective stage  Cercarie penetrate human skin within a few minutes after exposure  When they penetrate they lose their forked tail and transform into schistosomula  Schistosomula mature and reach mesentric veins(S.mansonii, S.japonicum. ) ,bladder vessels (S.haematobium)where they live and ovulate for duration of hosts life
  • 6. ADULT WORM Schistosoma mansoni Schistosoma japonicum
  • 7. INTERMEDIATE HOST  Schistosoma haematobolium- Bulinus truncatus  Schistosoma mansoni- Biomphalaria alexandria  Schistosomia japonicum- Oncomelania sp.  Schistosomia mekongi- Neotricula aperta
  • 10. PERIOD OF COMMUNICABILITY  Life span-5to 10 years, so infected human can excrete eggs up to 10 years  An infected snail can release cercarie from several weeks to 3 months of its life  An infected snail can lay eggs 300-3000/day
  • 11. SCHISTOSOMIASIS  SCHISTOSOMIASIS OR BILHARZIA  Disease affecting many people in developing countries.  ‘Acute schistosomiasis'- snail fever and cutaneous schistosomiasis  Low mortality rate, schistosomiasis can also be very debilitating  Bilharzia or bilharziosis, named after Theodor Bilharz, who first described the cause of urinary schistosomiasis in 1851.
  • 12. SYMPTOMS  Hepatosplenomegaly  Muscle atrophy  Anaemia  Diarrhea  Haemorrhage from the gastrointestinal tract
  • 13. DIAGNOSTIC STAGE  Schistosoma haematobolium  Eggs found in urine of urinary Schistosomiasis patients  Oval egg with terminal spine  Schistosoma mansoni  Eggs found in stool of intestinal Schistosomiasis patients  Oval egg with lateral spine
  • 14. MANAGEMENT  Contaminated water should be avoided  Sanitary disposal of sewage  Prevent contamination of water by feces and urine  Destruction of snails  Treat the patients  No vaccine is available  Praziquantel is effective against all species