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SCHIZOPHRENIA
WHAT IS
SCHIZOPHRENIA??
PSYCHOTIC CONDITION
CHARACTERIZED BY DISTURBANCE IN
THINKING, EMOTIONS,VOLITIONS
IN PRESENCE OF CLEAR
CONSCIOUSNESS.
3-4/1000 in every community
Men = Women
Rarely in children
Men > Women
Appear in late teen
or early adulthood
2/3 cases in range of 15-30 years
PEAK AGE: Men= 15-25 yr
women=25-35 yr
Common = lower socio
economic group
CLASSIFICATION
(DSM- IV )
•Delusions
•Hallucinations
•Disorganized speech
•Catatonia behavior
•Negative symptom(flat affect, alogia)
CLASSIFICATION
(ICD-10 TYPE)
• F20- Schizophrenia
• F20.0- Paranoid schizophrenia
• F20.1- hebephrenic schizophrenia
• F20.2- catatonic schizophrenia
• F20.3-undifferentiated schizophrenia
• F20.4- post-schizophrenic schizophrenia
• F20.5- residual schizophrenia
• F20.6- simple schizophrenia
CAUSE
BIOLOGICAL THEORIES
1. BIOCHEMICAL THEORIES: Dopamine Hypotheses
2. NEUROSTRUCTURAL THERIES: Undeveloped brain
parts(pre frontal and limbic cortex)
3. GENETIC THEORIES
4.PRE NATAL RISK
Genetic theories
• Most common = among consanguineous
marriages
• Identical twin affected 50%
fragmental twins affected 15%
brother/ sister affected 10%
one parent affected 15%
both parents effected 35%
general population 1%
PRE-NATAL RISKS
• Maternal influenza
• Pregnancy complication ( during labor and
delivery)
• Exposure to viral infection
• Low oxygen level during birth
PSYCHODYNAMIC THEORIES
• Developmental theories-
According Freud, in oral stage regression
present with use of defense mechanism
(denial, projection, reaction)
Individual have ego boundaries, inadequate ego
development, super ego, regression, love
hatred relationship.
• Family therapies –
A. Mother child relationship
B. Dysfunction family system
C. Double blind communication
• Stress models-
A. Stimulus based model
B. Response based model
C. Transaction based model
• Social factor-
more prevalent in areas of high mobility, member of low socio economic
classes.
Conditions associated with living in poverty, congested housing facilities,
absence of prenatal care, dealing with stressful event , changing lifestyle.
PHASES OF SCHIZOPHRENIA
Prodromal phase
(Social withdrawal, neglect personal hygiene, grooming, disturb in
communication, unusual perceptual experiences, lack of interest and
energy, inappropriate effect , eccentric behavior . Last for many
years.)
Active phase
( delusions, hallucination, positive symptoms , catatonic behavior,
disorganized speech, disorder of thought )
Residual phase
(occurs between episodes of psychosis, negative symptom, odd thinking
and behavior)
SYMPTOMS
• POSITIVE SYMPTOM
• NEGATIVE SYMPTOM
• OTHERS- 1] Cognitive deficits
2]mood symptom
3]thought and speech disorder
4] disorder of affect
5]motor behaviour disorder
6] perception disorder
7] other
Positive symptom
hallucination
delusion
bizarre behavior
thought disorder
suicidal thinking
NEGATIVE SYMPTOM
A logia
Flat Effect
A volition [ apathy]
Inattention
Self care deficit
COGNITIVE DISORDER
( Attention deficit , memory loss, executive
functions)
MOOD DISORDER
(Depression, dysphoria, BPAD ,dysthymia)
THOUGHT AND SPEECH DISOREDER
( Autistic thinking, loosening of association,
neologism, poverty of speech ,poverty of idea,
thought blocking)
DISORDER OF AFFECT
( apathy, emotional blunting, inappropriate
emotional responses, anhedonia)
DISORDER OF MOTOR BEHAVIOR
( / in psychomotor activity , grimacing, poor
grooming, self care deficit, mannerisms)
OTHERS
(decreased work function, excitement, insomnia
tension, withdrawal, loss of ego boundary,
suicide, poor judgment , loss of insight)
TYPES OF
SCHIZOPHRENIA
1.PARANOID
SCHIZOPHRENIA
Paranoid means delusions.
Characterized by some features:
> delusion of persecution
>delusion of jealousy
>delusion of grandiosity
>somatic delusion
> auditory hallucination
2.HEBEPHRENIC SCHIZOPHRENIA
( Known as disorganized schizophrenia)
A. Thought disorder
B. extreme social impairment
C. inappropriate emotions, laugh
D. senseless giggling
E. mirror gazing
F. grimacing
-It begins mostly in adolescent age or young adult.
3.CATATONIC SCHIZOPHRENIA
( marked disturbance of motor
behavior)
FORMS: A. Catatonic stupor
B. Catatonic excitement
C. Catatonic alteration
FEATURES: increase psychomotor activity, Increased speech
mutism, Posturing , negative symptoms, stupor
echolalia, rigidity,echopraxia, loosening association.
6.RESIDUAL
SCHIZOPHRENIA
When a person has a past history of at least one
episodes of schizophrenia, but has no currently
symptoms they are considered residual
schizophrenia.
But other symptoms are-
1.Emotional blunting
2.Illogical thinking
3.Odd beliefs
4.Loosening association
5.Social withdrawal
5.UNDIFFERENTIATED
SCHIZOPHRENIA
(In this, when a person exhibits behaviors which fit into
2 or more type of schizophrenia including symptoms
such as delusions , hallucination, disorganized speech ,
catatonic behave)
6. POST-SCHIZOPHRENIC
DISORDER
( It has depressive features in presence of residual or
simple schizophrenia . It has increased risk of suicide.)
7. SIMPLE SCHIZOPHRENIA
( It is characterized by negative symptom like avolition ,
apathy , anhedonia, lack of motivation , low activity with
absence of hallucination or delusions.
SYMPTOMS we can see-
A. aimless activity
B. Self absorbed idleness
HOW CAN WE DIAGNOSE IT??
-HISTORY
-PHYSICAL EXAMINATION
-NEUROLOGICAL EXAMINATION
-MENTAL STATUS EXAMINATION
-BLOOD TEST
HOW WILL WE TREAT A
SCHIZOPHRENIC PATIENT ??
OR
WHAT IS TREATMENT MODALITIES??
A. PHARMACOTHERAPY
• Anti anxiety drugs: thiopentone, oxazepam
• Anti depressants : sertraline, imipramine
• Mood stabilizer : lithium , carbamazepine
• Antipsychotics : clozapine, haloperidol
B.THERAPIES
• ECT (electro convulsive therapies)
• Psychological therapies are included
A. Psychosocial therapy
B. Group therapy
C. Behavior therapy
D. Social skill training
E. Cognitive therapy
F. Family therapy
C. REHABILITATION
> Develop working habit
>Training new skills
>Vocational guidance
>Independent job placement
>Chosen goal setting
>Maintain focusing
NURSING DIAGNOSIS FOR A
SCHIZOPHRENIA PATIENT
A. Impaired verbal communication related to
panic, anxiety , delusional thinking.
B. Disturbed thought process related to inability
to trust, anxiety , biochemical factors.
C. Self care deficit related to poor grooming,
not properly dressing, not maintaining
hygiene , disorganized daily living.
D. Risk for self inflicted related to suicidal ideas,
plans or attempts.
THANK YOU

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SCHIZOPHRENIA

  • 3. PSYCHOTIC CONDITION CHARACTERIZED BY DISTURBANCE IN THINKING, EMOTIONS,VOLITIONS IN PRESENCE OF CLEAR CONSCIOUSNESS.
  • 4. 3-4/1000 in every community Men = Women Rarely in children Men > Women Appear in late teen or early adulthood
  • 5. 2/3 cases in range of 15-30 years PEAK AGE: Men= 15-25 yr women=25-35 yr Common = lower socio economic group
  • 6. CLASSIFICATION (DSM- IV ) •Delusions •Hallucinations •Disorganized speech •Catatonia behavior •Negative symptom(flat affect, alogia)
  • 7. CLASSIFICATION (ICD-10 TYPE) • F20- Schizophrenia • F20.0- Paranoid schizophrenia • F20.1- hebephrenic schizophrenia • F20.2- catatonic schizophrenia • F20.3-undifferentiated schizophrenia • F20.4- post-schizophrenic schizophrenia • F20.5- residual schizophrenia • F20.6- simple schizophrenia
  • 9. BIOLOGICAL THEORIES 1. BIOCHEMICAL THEORIES: Dopamine Hypotheses 2. NEUROSTRUCTURAL THERIES: Undeveloped brain parts(pre frontal and limbic cortex) 3. GENETIC THEORIES 4.PRE NATAL RISK
  • 10. Genetic theories • Most common = among consanguineous marriages • Identical twin affected 50% fragmental twins affected 15% brother/ sister affected 10% one parent affected 15% both parents effected 35% general population 1%
  • 11. PRE-NATAL RISKS • Maternal influenza • Pregnancy complication ( during labor and delivery) • Exposure to viral infection • Low oxygen level during birth
  • 12. PSYCHODYNAMIC THEORIES • Developmental theories- According Freud, in oral stage regression present with use of defense mechanism (denial, projection, reaction) Individual have ego boundaries, inadequate ego development, super ego, regression, love hatred relationship.
  • 13. • Family therapies – A. Mother child relationship B. Dysfunction family system C. Double blind communication • Stress models- A. Stimulus based model B. Response based model C. Transaction based model • Social factor- more prevalent in areas of high mobility, member of low socio economic classes. Conditions associated with living in poverty, congested housing facilities, absence of prenatal care, dealing with stressful event , changing lifestyle.
  • 14. PHASES OF SCHIZOPHRENIA Prodromal phase (Social withdrawal, neglect personal hygiene, grooming, disturb in communication, unusual perceptual experiences, lack of interest and energy, inappropriate effect , eccentric behavior . Last for many years.) Active phase ( delusions, hallucination, positive symptoms , catatonic behavior, disorganized speech, disorder of thought ) Residual phase (occurs between episodes of psychosis, negative symptom, odd thinking and behavior)
  • 15. SYMPTOMS • POSITIVE SYMPTOM • NEGATIVE SYMPTOM • OTHERS- 1] Cognitive deficits 2]mood symptom 3]thought and speech disorder 4] disorder of affect 5]motor behaviour disorder 6] perception disorder 7] other
  • 17. NEGATIVE SYMPTOM A logia Flat Effect A volition [ apathy] Inattention Self care deficit
  • 18. COGNITIVE DISORDER ( Attention deficit , memory loss, executive functions) MOOD DISORDER (Depression, dysphoria, BPAD ,dysthymia) THOUGHT AND SPEECH DISOREDER ( Autistic thinking, loosening of association, neologism, poverty of speech ,poverty of idea, thought blocking)
  • 19. DISORDER OF AFFECT ( apathy, emotional blunting, inappropriate emotional responses, anhedonia) DISORDER OF MOTOR BEHAVIOR ( / in psychomotor activity , grimacing, poor grooming, self care deficit, mannerisms) OTHERS (decreased work function, excitement, insomnia tension, withdrawal, loss of ego boundary, suicide, poor judgment , loss of insight)
  • 21. 1.PARANOID SCHIZOPHRENIA Paranoid means delusions. Characterized by some features: > delusion of persecution >delusion of jealousy >delusion of grandiosity >somatic delusion > auditory hallucination
  • 22. 2.HEBEPHRENIC SCHIZOPHRENIA ( Known as disorganized schizophrenia) A. Thought disorder B. extreme social impairment C. inappropriate emotions, laugh D. senseless giggling E. mirror gazing F. grimacing -It begins mostly in adolescent age or young adult.
  • 23. 3.CATATONIC SCHIZOPHRENIA ( marked disturbance of motor behavior) FORMS: A. Catatonic stupor B. Catatonic excitement C. Catatonic alteration FEATURES: increase psychomotor activity, Increased speech mutism, Posturing , negative symptoms, stupor echolalia, rigidity,echopraxia, loosening association.
  • 24. 6.RESIDUAL SCHIZOPHRENIA When a person has a past history of at least one episodes of schizophrenia, but has no currently symptoms they are considered residual schizophrenia. But other symptoms are- 1.Emotional blunting 2.Illogical thinking 3.Odd beliefs 4.Loosening association 5.Social withdrawal
  • 25. 5.UNDIFFERENTIATED SCHIZOPHRENIA (In this, when a person exhibits behaviors which fit into 2 or more type of schizophrenia including symptoms such as delusions , hallucination, disorganized speech , catatonic behave)
  • 26. 6. POST-SCHIZOPHRENIC DISORDER ( It has depressive features in presence of residual or simple schizophrenia . It has increased risk of suicide.)
  • 27. 7. SIMPLE SCHIZOPHRENIA ( It is characterized by negative symptom like avolition , apathy , anhedonia, lack of motivation , low activity with absence of hallucination or delusions. SYMPTOMS we can see- A. aimless activity B. Self absorbed idleness
  • 28. HOW CAN WE DIAGNOSE IT?? -HISTORY -PHYSICAL EXAMINATION -NEUROLOGICAL EXAMINATION -MENTAL STATUS EXAMINATION -BLOOD TEST
  • 29. HOW WILL WE TREAT A SCHIZOPHRENIC PATIENT ?? OR WHAT IS TREATMENT MODALITIES??
  • 30. A. PHARMACOTHERAPY • Anti anxiety drugs: thiopentone, oxazepam • Anti depressants : sertraline, imipramine • Mood stabilizer : lithium , carbamazepine • Antipsychotics : clozapine, haloperidol
  • 31. B.THERAPIES • ECT (electro convulsive therapies) • Psychological therapies are included A. Psychosocial therapy B. Group therapy C. Behavior therapy D. Social skill training E. Cognitive therapy F. Family therapy
  • 32. C. REHABILITATION > Develop working habit >Training new skills >Vocational guidance >Independent job placement >Chosen goal setting >Maintain focusing
  • 33. NURSING DIAGNOSIS FOR A SCHIZOPHRENIA PATIENT A. Impaired verbal communication related to panic, anxiety , delusional thinking. B. Disturbed thought process related to inability to trust, anxiety , biochemical factors. C. Self care deficit related to poor grooming, not properly dressing, not maintaining hygiene , disorganized daily living. D. Risk for self inflicted related to suicidal ideas, plans or attempts.