SHAPE Society

1. 1
MR Angiography 3D with Gadolinium-DTPA in
Watanabe Rabbit
Before SPIO injection 5 Days After SPIO injection
Iron (SPIO) accumulation in the aortic plaques
creates irregular darkening effects.

2. 2
MRI Identifies Plaque Inflammation by SPIO Nanoparticles
Watanabe rabbit
Post-SPIO
Watanabe rabbit
control
NZW rabbit
control
NZW rabbit
Post-SPIO
Watanabe Rabbit
Post-SPIO
Watanabe Rabbit
Control
NZW Rabbit
Post-SPIO
NZW Rabbit
Control

3. 3
 Am Heart J. 2003 May;145(5):813-20.Am Heart J. 2003 May;145(5):813-20.
Angiographic "plaque blush" is shown in theAngiographic "plaque blush" is shown in the
proximal right coronary artery (arrow) just afterproximal right coronary artery (arrow) just after
injection (injection (AA) and approximately 2 seconds later,) and approximately 2 seconds later,
when the main dye column has passed from thewhen the main dye column has passed from the
second portion of the artery to the bifurcation of thesecond portion of the artery to the bifurcation of the
posterior descending artery and posterolateral leftposterior descending artery and posterolateral left
ventricular branches (ventricular branches (BB). Preinjection and late). Preinjection and late
postinjection frames showed no opacity at the site,postinjection frames showed no opacity at the site,
excluding calcium as the cause of the opacity.excluding calcium as the cause of the opacity.

4. 4Figure A
Arrow correct?
(EF)

5. 5Figure B
Arrow correct?
(EF)

6. 6

7. 6