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Bovine Diseases
Shipping Fever Complex
• IBR- Infectious Bovine Rhinotracheitis (
  rednose)
• P13- Parainfluenza Type 3
• BSRV- Bovine Syncytial Respiratory Virus
• +/- Pastuerella multocida ( bacterial infection
  secondary to viral infection)
• Symptoms
- Fever 103-105, duration 3-5 days
- Loss of appetite
- Dry hacking cough ( +/- tracheal reaction with
  palpation)
- Serous nasal/ocular discharge
- +/- rhinitis/conjunctivitis
• Treatment
- In uncomplicated cases, treatment is rarely
   necessary
• Transmission
- aerosol, morbidity directly related to
management techniques
• Prevention
- vaccination, preconditioning program
• Note: recovery from natural infection with
  IBR/P13/BRSV results in lifelong immunity
• Economic impact
- Weight loss, decreased rate of gain/carcass
devaluation
• Epidemiology
- High ( 80%) rate of exposure/antibody
  production
- Morbidity 50-70%
- Mortality <5%
Bovine Viral Diarrhea
                   BVD
• Infection can result in immunosuppression,
  may be factor in susceptibility to other
  diseases
• Symptoms
- mild, transient diarrhea, many subclinical
- 80% of cattle >1yr have antibodies to BVD
- High morbidity( 100%) low mortality (0%)
- 1-2 % viremic for life, resevoirs of infection
BVD Mucosal disease
• Low morbidity (5-10%), high mortality ( 95-
  100%)
• Symptoms:
- Excessive salivation/oral erosion
- Oral mucosa has cooked appearance
- Watery diarrhea with blood/mucus/sloughed
  intestinal mucosa
- Smells like parvo diarrhea
BVD continued
• Treatment – fluid replacement +/- antibiotics
• Prevention- vaccination
Rotavirus/coronavirus
• Virus is ONLY in the intestinal tract, does not
  enter body
• Symptoms- profuse watery/yellow diarrhea
  +/- flecks of blood
• Treatment- fluid, electrolyte replacement
Rotavirus/coronavirus cont’
• Prevention
- Sanitation at calving
- Maternal vaccination pre-calving
- Protection is dependent on the presence of
  colostral antibodies in the lumen of the
  intestine. Serum antibodies are of no benefit
  as virus does not leave GI tract
- Stimulate calf’s immunity with oral vaccine at
  birth
Fluid management of diarrhea in
                calves
• Colostrum requirement 1 pint per 20 lbs of
  body weight within 1 hour of birth and repeat
  within 12 hours
• Maintenance milk requirement 10% of the
  calf’s body weight in milk or milk replacer/day
• Maintain 2 hour interval between milk
  feedings and oral electrolyte replacement
  requirements
Dehydration
• 5% dehydration: dehydration, no other clinical
  signs, calf nursing normally
• 7% dehydration: eyes slightly sunken, skin
  losing elasticity
• 9% dehydration: eyes sunken, gums tacky, calf
  depressed
• 12% dehydration: skin tents, calf recumbent,
  non-responsive
Dehydration cont’
• Multiply percentage of dehydration by weight
  of calf( in Kg ) to determine the number of
  liters of electrolyte solution required for
  replacement
• NOTE: replacement fluids are administered in
  addition to the calf’s maintenance
  requirement for milk
Infectious Bovine Keratitis
                Pinkeye
• Bacteria: Moraxella bovis
• Transmission
- Flying insects
- Solar radiation and environmental conditions
  (dust) exacerbating factors
• Symptoms
- tearing, blepharospasm, photophobia
- Corneal opacity
Pinkeye cont’
• Duration of symptoms
- 3-5 weeks
- Note: weaning weight may be decreased by
  10% as a result of pinkeye infection
• Treatment
- Subconjunctival penicillin and dexamethasone
- Eye patch
Pinkeye cont’
• Prevention
- Insect control
- Natural infection confers immunity for 12
  months
- Vaccine is available but of questionable
  efficacy
Esophageal obstruction
                  Choke
• Symptoms- excessive salivation (loss of
  bicarbonate>acidosis) dehydration
• Treatment
- Relieve obstruction, sedation
- Head position is critical to avoid aspiration pneumonia
- Lavage/probing ( has corkscrew end to try and snag
  obstruction)
- Fluid/electrolyte replacement as necessary
- Warning: symptoms of choke may resemble those of
  rabies, always assume rabies first
Urethral Calculi
                water belly
• Symptoms
- Straining to urinate, urine dribbling
- Ventral subcu edema/fluid accumulation (
  post urethral rupture)
• Causes- early castration reduces urethral
  diameter, stress at weaning, inadequate
  conditioning, environmental factors lack of
  water, frozen water tanks
• Treatment- urethrostomy at location of calculi
Squamous Cell Carcinoma
• Cause- solar radiation and unpigmented skin
  like in Hereford cattle
• Treatment- enucleation
• Economic impact- cost of veterinary care and
  carcass devaluation
Traumatic reticulitis/pericarditis
          Hardware disease
• Incidence- cattle eating hay made from or
  grazing on field containing old rusting fences,
  baling wire, or in vicinity of a building that was
  torn down
• Symptoms- sharp drop in milk production,
  arched back, grunting when pressure is
  exerted on the xiphoid process
Hardware disease
• Treatment- rumen magnets, traumatic
  pericarditis may require surgery, rib resection
  and pericardial drainage
• Prevention- monitor quality of feeds and
  pasture
Rumenal tympany
                   Bloat
• Incidence-
- cattle turned out on lush pasture, frothy bloat
- Cattle fed a diet with low roughages to
  concentrate ratio, gas bloat
• Symptoms
- Distension of left flank, dyspnea, collapse, sudden
  death
- If untreated, death occurs within 3-4 hours of
  onset of symptoms
Bloat
• Treatment
- Surfactants administered via stomach tube
- Trocharization of rumen
- Rumenotomy
• Prevention
- Restrict access to new pasture
- Feed hay before turning cattle out on new
  pasture
- Prophylactic use of antifoaming agents
Clostridial diseases
• Anaerobic bacteria
- Gas producing, toxin producing, spore
  producing
- Sensitive to penicillin
- Unbiquitous in environment
- Speciation variation in susceptibility
Clostridial diseases of cattle
• Cl chauvei- blackleg
• Cl. Septicum- malignant edema
• Cl. Novyi- Blacks disease
• Cl. Hemolyticum- Redwater disease
• Cl. Perfringen Type C- Hemorrhagic enteritis
Prevention- vaccination
Leptospirosis
• Agent- spirochete
• Transmission- organisms in urine of affected
  animals, may be asymptomatic
• Symptoms
- Chronic infection, abortions, stillbirths, weak
  calves
- Acute infection, jaundice, fever, death
Lepto con’t
• Treatment
- Acute infection, antibodies
- Chronic infection, no treatment
• Prevention
- vaccination
Post parturient paresis
                   Milk Fever
•   Incidence
-   Usually within 72 hours of calving
•   Symptoms
-   unsteadiness, sternal recumbency with head
    displaced to the side, intestinal stasis, loss of
    anal tone and death
Milk Fever Con’t
• Diagnosis
- symptoms, interval post calving
- Blood calcium levels 3-7 mg/dl ( normal 10
  mg/dl)
• Treatment – IV calcium
• Prevention
- Dry period nutrition
- Calcium supplementation,
Displace Abomassum
• Abomassum becomes distended with gas and
  or fluid and shifts to an abnormal position
  between the rumen and left abdominal wall
• Incidence- occurs withing 2 weeks of calving,
  associated with high concentrate level in diet
  during dry period
• Diagnosis- abdominal percussion, ping sound
• Treatment- roll cow, surgery
Ketosis
• Symptoms- inappetance, constipation, mucus
  covered feces, decreased milk production,
  breath has acetone odor
• Incidence- usually secondary to other disease
• Diagnosis- ketonuria, ketonemia, ketones in
  milk
• Treatment- glucocorticoids, address
  precipitating conditions
Brucellosis
               Bang’s disease
• Brucella abortus
• Symptoms- abortion, infertility, birth of weak
  calves, enlarged, arthritic joints
• Transmission- bacteria shed in milk, aborted
  fetus, placenta or reproductive tract
  discharges
Brucellosis Control
• Brucellosis Eradication Program
• Surveillance
- Bulk milk tank screening with Brucellosis Ring
  Test
- Non milk producing animals tested at market
  or slaughter with Brucellosis Card Test
Eradication program con’t
• Disease identification
- Herd quarantined, movement to slaughter
  only
• Prevention
- vaccination, strain 19, Strain RB51
- Test all replacement animals, quarantine
  before admission to general population
Johne’s disease
• Mycobacterium paratuberculosis
• Symptoms
- Chronic diarrhea
- Weight loss, unthriftiness, emaciation
• Transmission
- Oral bacteria excreted in feces and milk
including colostrum
Johnes Control
• Avoid feeding raw, unpasteurized milk
• Do not permit offspring to nurse off infected dam
• Maintain colostrum from Johne’s negative
  females
• Do not pool colostrum from multiple animals
• Avoid manure contamination of feed
  bunks/water troughs
• Premise disinfection, chemicl tuberculoid
• NOTE: will take 5+ years to eliminate Johne’s
Actinobacillosis
             Wooden Tongue
• Normal inhabitant of the bovine mouth an
  rumen that Actinobacillosis lignieresii that
  enters wound in the mouth, especially the
  tongue
• Symptoms- inability to prehend food,
  excessive salivation, anorexia, tongue
  protrudes ( make sure not rabies)
• Treatment- sodium iodide 70 mg/kg IV repeat
  in 1 week
Actinomyces
                 Lumpy Jaw
• Caused by Actinomyces bovis which is a
  normal inhabitant of the bovine mouth which
  enters a wound
• Symptoms- hard immoveable painless mass
  on mandible and may cause loose teeth
• Treatment- sodium iodide 70 mg/kg IV or
  penicillin 10,000 U/kg in valuable animals BID,
  treat any fistulas tracts that develop

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Shipping Fever Complex and Bovine Respiratory Diseases

  • 2. Shipping Fever Complex • IBR- Infectious Bovine Rhinotracheitis ( rednose) • P13- Parainfluenza Type 3 • BSRV- Bovine Syncytial Respiratory Virus • +/- Pastuerella multocida ( bacterial infection secondary to viral infection)
  • 3. • Symptoms - Fever 103-105, duration 3-5 days - Loss of appetite - Dry hacking cough ( +/- tracheal reaction with palpation) - Serous nasal/ocular discharge - +/- rhinitis/conjunctivitis
  • 4. • Treatment - In uncomplicated cases, treatment is rarely necessary • Transmission - aerosol, morbidity directly related to management techniques
  • 5. • Prevention - vaccination, preconditioning program • Note: recovery from natural infection with IBR/P13/BRSV results in lifelong immunity • Economic impact - Weight loss, decreased rate of gain/carcass devaluation
  • 6. • Epidemiology - High ( 80%) rate of exposure/antibody production - Morbidity 50-70% - Mortality <5%
  • 7. Bovine Viral Diarrhea BVD • Infection can result in immunosuppression, may be factor in susceptibility to other diseases • Symptoms - mild, transient diarrhea, many subclinical - 80% of cattle >1yr have antibodies to BVD - High morbidity( 100%) low mortality (0%) - 1-2 % viremic for life, resevoirs of infection
  • 8. BVD Mucosal disease • Low morbidity (5-10%), high mortality ( 95- 100%) • Symptoms: - Excessive salivation/oral erosion - Oral mucosa has cooked appearance - Watery diarrhea with blood/mucus/sloughed intestinal mucosa - Smells like parvo diarrhea
  • 9. BVD continued • Treatment – fluid replacement +/- antibiotics • Prevention- vaccination
  • 10. Rotavirus/coronavirus • Virus is ONLY in the intestinal tract, does not enter body • Symptoms- profuse watery/yellow diarrhea +/- flecks of blood • Treatment- fluid, electrolyte replacement
  • 11. Rotavirus/coronavirus cont’ • Prevention - Sanitation at calving - Maternal vaccination pre-calving - Protection is dependent on the presence of colostral antibodies in the lumen of the intestine. Serum antibodies are of no benefit as virus does not leave GI tract - Stimulate calf’s immunity with oral vaccine at birth
  • 12. Fluid management of diarrhea in calves • Colostrum requirement 1 pint per 20 lbs of body weight within 1 hour of birth and repeat within 12 hours • Maintenance milk requirement 10% of the calf’s body weight in milk or milk replacer/day • Maintain 2 hour interval between milk feedings and oral electrolyte replacement requirements
  • 13. Dehydration • 5% dehydration: dehydration, no other clinical signs, calf nursing normally • 7% dehydration: eyes slightly sunken, skin losing elasticity • 9% dehydration: eyes sunken, gums tacky, calf depressed • 12% dehydration: skin tents, calf recumbent, non-responsive
  • 14. Dehydration cont’ • Multiply percentage of dehydration by weight of calf( in Kg ) to determine the number of liters of electrolyte solution required for replacement • NOTE: replacement fluids are administered in addition to the calf’s maintenance requirement for milk
  • 15. Infectious Bovine Keratitis Pinkeye • Bacteria: Moraxella bovis • Transmission - Flying insects - Solar radiation and environmental conditions (dust) exacerbating factors • Symptoms - tearing, blepharospasm, photophobia - Corneal opacity
  • 16. Pinkeye cont’ • Duration of symptoms - 3-5 weeks - Note: weaning weight may be decreased by 10% as a result of pinkeye infection • Treatment - Subconjunctival penicillin and dexamethasone - Eye patch
  • 17. Pinkeye cont’ • Prevention - Insect control - Natural infection confers immunity for 12 months - Vaccine is available but of questionable efficacy
  • 18. Esophageal obstruction Choke • Symptoms- excessive salivation (loss of bicarbonate>acidosis) dehydration • Treatment - Relieve obstruction, sedation - Head position is critical to avoid aspiration pneumonia - Lavage/probing ( has corkscrew end to try and snag obstruction) - Fluid/electrolyte replacement as necessary - Warning: symptoms of choke may resemble those of rabies, always assume rabies first
  • 19. Urethral Calculi water belly • Symptoms - Straining to urinate, urine dribbling - Ventral subcu edema/fluid accumulation ( post urethral rupture) • Causes- early castration reduces urethral diameter, stress at weaning, inadequate conditioning, environmental factors lack of water, frozen water tanks • Treatment- urethrostomy at location of calculi
  • 20. Squamous Cell Carcinoma • Cause- solar radiation and unpigmented skin like in Hereford cattle • Treatment- enucleation • Economic impact- cost of veterinary care and carcass devaluation
  • 21. Traumatic reticulitis/pericarditis Hardware disease • Incidence- cattle eating hay made from or grazing on field containing old rusting fences, baling wire, or in vicinity of a building that was torn down • Symptoms- sharp drop in milk production, arched back, grunting when pressure is exerted on the xiphoid process
  • 22. Hardware disease • Treatment- rumen magnets, traumatic pericarditis may require surgery, rib resection and pericardial drainage • Prevention- monitor quality of feeds and pasture
  • 23. Rumenal tympany Bloat • Incidence- - cattle turned out on lush pasture, frothy bloat - Cattle fed a diet with low roughages to concentrate ratio, gas bloat • Symptoms - Distension of left flank, dyspnea, collapse, sudden death - If untreated, death occurs within 3-4 hours of onset of symptoms
  • 24. Bloat • Treatment - Surfactants administered via stomach tube - Trocharization of rumen - Rumenotomy • Prevention - Restrict access to new pasture - Feed hay before turning cattle out on new pasture - Prophylactic use of antifoaming agents
  • 25. Clostridial diseases • Anaerobic bacteria - Gas producing, toxin producing, spore producing - Sensitive to penicillin - Unbiquitous in environment - Speciation variation in susceptibility
  • 26. Clostridial diseases of cattle • Cl chauvei- blackleg • Cl. Septicum- malignant edema • Cl. Novyi- Blacks disease • Cl. Hemolyticum- Redwater disease • Cl. Perfringen Type C- Hemorrhagic enteritis Prevention- vaccination
  • 27. Leptospirosis • Agent- spirochete • Transmission- organisms in urine of affected animals, may be asymptomatic • Symptoms - Chronic infection, abortions, stillbirths, weak calves - Acute infection, jaundice, fever, death
  • 28. Lepto con’t • Treatment - Acute infection, antibodies - Chronic infection, no treatment • Prevention - vaccination
  • 29. Post parturient paresis Milk Fever • Incidence - Usually within 72 hours of calving • Symptoms - unsteadiness, sternal recumbency with head displaced to the side, intestinal stasis, loss of anal tone and death
  • 30. Milk Fever Con’t • Diagnosis - symptoms, interval post calving - Blood calcium levels 3-7 mg/dl ( normal 10 mg/dl) • Treatment – IV calcium • Prevention - Dry period nutrition - Calcium supplementation,
  • 31. Displace Abomassum • Abomassum becomes distended with gas and or fluid and shifts to an abnormal position between the rumen and left abdominal wall • Incidence- occurs withing 2 weeks of calving, associated with high concentrate level in diet during dry period • Diagnosis- abdominal percussion, ping sound • Treatment- roll cow, surgery
  • 32. Ketosis • Symptoms- inappetance, constipation, mucus covered feces, decreased milk production, breath has acetone odor • Incidence- usually secondary to other disease • Diagnosis- ketonuria, ketonemia, ketones in milk • Treatment- glucocorticoids, address precipitating conditions
  • 33. Brucellosis Bang’s disease • Brucella abortus • Symptoms- abortion, infertility, birth of weak calves, enlarged, arthritic joints • Transmission- bacteria shed in milk, aborted fetus, placenta or reproductive tract discharges
  • 34. Brucellosis Control • Brucellosis Eradication Program • Surveillance - Bulk milk tank screening with Brucellosis Ring Test - Non milk producing animals tested at market or slaughter with Brucellosis Card Test
  • 35. Eradication program con’t • Disease identification - Herd quarantined, movement to slaughter only • Prevention - vaccination, strain 19, Strain RB51 - Test all replacement animals, quarantine before admission to general population
  • 36. Johne’s disease • Mycobacterium paratuberculosis • Symptoms - Chronic diarrhea - Weight loss, unthriftiness, emaciation • Transmission - Oral bacteria excreted in feces and milk including colostrum
  • 37. Johnes Control • Avoid feeding raw, unpasteurized milk • Do not permit offspring to nurse off infected dam • Maintain colostrum from Johne’s negative females • Do not pool colostrum from multiple animals • Avoid manure contamination of feed bunks/water troughs • Premise disinfection, chemicl tuberculoid • NOTE: will take 5+ years to eliminate Johne’s
  • 38. Actinobacillosis Wooden Tongue • Normal inhabitant of the bovine mouth an rumen that Actinobacillosis lignieresii that enters wound in the mouth, especially the tongue • Symptoms- inability to prehend food, excessive salivation, anorexia, tongue protrudes ( make sure not rabies) • Treatment- sodium iodide 70 mg/kg IV repeat in 1 week
  • 39. Actinomyces Lumpy Jaw • Caused by Actinomyces bovis which is a normal inhabitant of the bovine mouth which enters a wound • Symptoms- hard immoveable painless mass on mandible and may cause loose teeth • Treatment- sodium iodide 70 mg/kg IV or penicillin 10,000 U/kg in valuable animals BID, treat any fistulas tracts that develop