2. Meningitis is an acute inflammation of the protective
membranes covering the brain and spinal cord, known
collectively as the meninges
The most common causes of meningitis are viral and
bacterial infections. Other causes may include:
cancer
chemical irritation
fungi
drug allergies
Some viral and bacterial meningitis are contagious.
They can be transmitted by coughing, sneezing, or
close contact.
3. Viral meningitis
Viral meningitis is the most common type of
meningitis.
These include:
West Nile virus
influenza
mumps
HIV
measles
herpes viruses
4. Streptococcus pneumoniae, which is typically
found in the respiratory tract, sinuses, and nasal
cavity”
Neisseria meningitidis, which is spread through
saliva and other respiratory fluids
Haemophilus influenza, which can cause not only
meningitis but infection of the blood, inflammation
of the windpipe, cellulitis, and infectious arthritis
Listeria monocytogenes, which are foodborne
bacteria
Staphylococcus aureus, which is typically found
on the skin and in the respiratory tract,
6. Tuberculosis meningitis is caused by
mycobacterium tuberculosis which is a
severe infection that carries a high
morbidity and mortality
7. Non-infectious meningitis : Non-infectious
meningitis is not an infection. Instead, it is a type of
meningitis that’s caused by other medical conditions
or treatments. These include:
a head injury
brain surgery
cancer
certain medications
8. Bloodstream: Middle ear infection, mastoiditis,
sinusitis, cellulitis or any other infection of body.
Direct extension: fracture of frontal or facial
bone.
CSF infection: poor sterile technique during
lumbar puncture or spinal surgery
Mouth and Nasopharynx
In utero: during amniocentesis, maternal
infection such as rubella etc.
9. Microorganism and viruses enters the nervous
system by many routes.
The infection spreads rapidly throught the Meninges
and invades the ventricles
Increase CSF production with moderate increase
in pressure
Cerebral edema and increased ICP
CSF in subarchnoid space and archnoid membrane
become infected
10. Fever
Severe headache
Nausea and vomiting
Nuchal rigidity ( resistance to flexion of neck)
Positive Kernig’s sign (inability of patient to extend the
legs when the knee is flexed at hip)
Positive Brudzinski’s sign ( the hip and knee flex when
the patient neck is flexed)
Photophobia
A decreased level of consciousness (LOC)
Sign of increased ICP
Coma is associated with poor prognosis
11.
12.
13.
14. History collection, physical examination
Analysis of CSF
CBC, coagulation profile, electrolyte
level, glucose, platelet count
Blood culture
Urine specific gravity (1.010-1.030)
CT Scan, MRI, EEG,
Chest X-rays can reveal the presence of
pneumonia, tuberculosis
16. Meningitis is potentially life-threatening and has a
high mortality rate if untreated;
Intravenous fluids should be administered if
hypotension (low blood pressure) or shock are
present.
Mechanical ventilation may be needed if the level of
consciousness is very low, or if there is evidence of
respiratory failure
Treatments to decrease the intracranial pressure
with medication (e.g. mannitol).
Seizures are treated with anticonvulsants
Hydrocephalus may require insertion of a temporary
or long-term drainage device, such as a cerebral
shunt
17. Antibiotics: (e.g. rifampicin, ciprofloxacin or
ceftriaxone)
corticosteroids (usually dexamethasone)
treatment with antiviral drugs such as
aciclovir
Antifungals medication
Seizure (phenytoin)
18. Assess neurological status vital sign constently
Oxygenation, pulse oximetry
Assess blood pressure
IV fluids
Reduce high fever
Protect patient from injury
Monitor daily weight, serum electrolyte, urine
specific gravity
Prevent complication associated with immobility
Infection control
Inform family about patients condition
19. Ineffective Tissue Perfusion
Observe for any signs of increased
intracranial pressure.
Monitor arterial blood gases (ABGs) and
oxygen saturation.
Maintain head or neck in midline position,
provide small pillow for support.
Administer oxygen as needed.
Osmotic diuretic: Mannitol
Anticonvulsants: Diazepam (Valium) or
phenytoin (Dilantin)
20. Hyperthermia:
Assess the vital signs closely.
Perform tepid sponge.
Maintain adequate fluid intake as tolerated.
Administer antibiotics
Administer antipyretics as indicated.