This document discusses the central dogma of DNA and its importance in medical research and treatment. It begins with an introduction to the central dogma - that DNA is located in the nucleus and controls protein synthesis in the cytoplasm through DNA to RNA to protein. It then summarizes several recent studies involving controlling gene expression and cell growth, developing RNA vaccines, and using knowledge of the central dogma for therapeutic purposes like improving cancer treatments. In the conclusion, a student observes that understanding how the central dogma relates to medicine today can help with disease diagnosis and treatment.

1. CENTRAL
DOGMA OF DNA
BY
SEBASTIAN ARBELAEZ MONTOYA

4. INTRODUCTION
DNA is located in the
nucleus and protein
synthesis in the cytoplasm
DNA RNA PROTEIN

5.  Researchers find how proteins
control gene expression by binding
both DNA and RNA.
 Published: Monday 8 August 2016

6. Regulated
Detention of cell cycle at G1
DNA replication

7. Mutant p53s can
promote tumour
growth

8.  Genetic evidence has
implicated both Mdm2
and MdmX as
essential in negative
regulation of p53

9. Student´s observation
By being able to control cell growth
since the early part of mitosis can
better respond to treatments because
it prevents carcinogens from the G1
phase of accelerated growth there ,
avoiding the whole process of
replication , transcription and
translation

10.  Customizable RNA vaccine successful
in mice
 Published: Jul 6, 2016 at 8:20am

11. Is injected an take days
to make effect

12. We have very
similar
immune
system of mice
It could be
applied the
treatment of
human

13. New project!!!: working on
cancer vaccines to teach the
immune system to identify and
attack tumors.

14. Student´s observation
The ARN vaccine it is a very
important discovery because
it causes a dose of the
messenger, could translate for
the production of proteins
that prevent or attack the
infectios and other things

16.  All these studies are of great
importance involved in the use of
knowledge of central dogma for
therapeutic uses improving the
quality of life

17. First study…
 I think that not only
should give
importance to the
knowledge of the
central dogma , but
also know how this
related to medicine
today because it helps
us to treatment and
diagnosis of important
diseases as referred to
in this news

18. Second study…
 It is important to know that these
components are involved in the
central dogma , as their knowledge
has been possible not only know the
genes, but act to change for better
use and therapy

19. BIBLIOGRAPHY
 A-S Tournillon, I López, L Malbert-Colas, S Findakly, N
Naski, V Olivares-Illana, K Karakostis, B Vojtesek, K
Nylander and R Fåhraeus,Oncogene, (4 July 2016).
MEDICAL NEWS TODAY. Retrieved from:
http://www.medicalnewstoday.com/releases/312174.ph
p#post
 Amirah Al Idrus (july 4 2016). FIERCE BIOTECH.
Retrieved from:
http://www.fiercebiotech.com/research/customizable-
rna-vaccine-successful-mice
 MARTINEZ SÁNCHEZ, Lina María. Biología molecular. 2.
ed. Medellín: UPB. Fac. de Medicina, 2006. p 97-100

20. THANK YOU!!!