Pascal Nataf, CEO, Affordance Studio Kim Berthiaume, Creative Director, Affordance Studio This presentation was given at the 2016 Serious Play Conference, hosted by the UNC Kenan-Flagler Business School. Making a game for a museum is both challenging and invigorating. In 2015, the Montreal Science Centre decided to create a video game to enhance its upcoming exposition on the human body. This talk will present the case study of Morbus Delirium, a transmedia experience in which the users must cure an infectious disease.