Cancer metastasis detection with neural conditional random field

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Dr. Yi Li, Machine Learning Research Scientist, Baidu Silicon Valley AI Lab

Technologie

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Baidu Research
Silicon Valley AI Lab
Using Deep Learning to Help Pathologists Find Tumors
Yi Li, Baidu Silicon Valley AI Lab
11/14/2018Yi Li 1
MLconf 2018, San Francisco

||
Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 2
Pathology for cancer diagnosis
(source from Google Image)

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Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 3
Reviewing pathology slides can be difficult…
40X WSI
1GB+, ~100K * ~100K pixels
Tumor
Deep learning?

||
Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 4
Most existing methods
Patch based deep CNN classifier
Tumor or Normal?
(source from Lunit Inc)
D. Wang, et al. 2016
B. Geçer, 2016
L. Hou, 2016
Y. Liu, 2017
H. Lin, 2017
…

||
Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 5
Hard negatives
Tumor?Tumor?

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Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 6
Google

||
Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 7
Our method(NCRF)

||
Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 8
Our method captures spatial correlations

||
Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 9
Our method vs previous
Raw image Pathologist annotation
Previous method Our method

||
Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 10
Our method vs previous championship
ours = 0.8096

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Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 11
Our method vs previous championship
FROC curves on the test set with random seed 0

||
Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 12
Paper accepted to MIDL 2018

||
Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 13
Code is open sourced!!!
https://github.com/baidu-research/NCRF

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Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 14
Press report

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Baidu Research
Silicon Valley AI Lab
11/14/2018Yi Li 15
Thank you!
liyi17@baidu.com
Questions?

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Cancer metastasis detection with neural conditional random field

1. || Baidu Research Silicon Valley AI Lab Using Deep Learning to Help Pathologists Find Tumors Yi Li, Baidu Silicon Valley AI Lab 11/14/2018Yi Li 1 MLconf 2018, San Francisco

2. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 2 Pathology for cancer diagnosis (source from Google Image)

3. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 3 Reviewing pathology slides can be difficult… 40X WSI 1GB+, ~100K * ~100K pixels Tumor Deep learning?

4. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 4 Most existing methods Patch based deep CNN classifier Tumor or Normal? (source from Lunit Inc) D. Wang, et al. 2016 B. Geçer, 2016 L. Hou, 2016 Y. Liu, 2017 H. Lin, 2017 …

5. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 5 Hard negatives Tumor?Tumor?

6. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 6 Google

7. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 7 Our method(NCRF)

8. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 8 Our method captures spatial correlations

9. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 9 Our method vs previous Raw image Pathologist annotation Previous method Our method

10. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 10 Our method vs previous championship ours = 0.8096

11. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 11 Our method vs previous championship FROC curves on the test set with random seed 0

12. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 12 Paper accepted to MIDL 2018

13. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 13 Code is open sourced!!! https://github.com/baidu-research/NCRF

14. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 14 Press report

15. || Baidu Research Silicon Valley AI Lab 11/14/2018Yi Li 15 Thank you! liyi17@baidu.com Questions?

Notes de l'éditeur

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Cancer metastasis detection with neural conditional random field

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