The document outlines guidelines for semen banking and artificial insemination using donor sperm (AID) in India. It discusses requirements for sperm donors and semen banks, including that semen banks must be professionally run and follow international standards for cryopreservation. Banks can only use sperm from a single donor for 10 successful pregnancies and no more than 75 uses total. Consent from the recipient couple is required for any treatment.

1. ICMR guidelines for Semen
banking and IUI donor

2. *A sperm bank, semen bank or cryobank is a
facility or enterprise that collects and stores
human sperm from sperm donors for use by women
who need donor-provided sperm to achieve
pregnancy.
**Either an ART clinic or a law firm or any other
suitable independent organization may set up a
semen bank. If set up by an ART clinic it must
operate as a separate identity.

3. ** On request for semen by an ART clinic, the bank will provide the
clinic with a list of donors (without the name or the address but
with a code number) giving all relevant details
**The semen bank shall not supply semen of one donor for more
than ten successful pregnancies. It will be the responsibility of the
ART clinic or the patient, as appropriate, to inform the bank about a
successful pregnancy. The bank shall keep a record of all semen
received, stored and supplied, and details of the use of the semen
of each donor. This record will be liable to be reviewed by the
accreditation authority

4. An ART bank shall not supply the sperm of a single
donor for use more than seventy five times.
One sample of semen supplied by an ART bank shall be
used by the assisted reproductive technology clinic
only once on only one recipient.

5. * The bank must be run professionally and must have facilities
for cryopreservation of semen, following internationally
accepted protocols. Each bank will prepare its own SOP
(Standard Operating Procedures) for cryopreservation.
**Semen samples must be cryopreserved for at least six months
before first use, at which time the semen donor must be tested
for HIV and hepatitis B and C.
**The bank must ensure confidentiality in regard to the identity
of the semen donor.
**The identity of the recipient shall not be made known to the
donor.

6. Freezing of semen
Men that are likely to suffer from psychological stress at the
time of ovum pick-up or those who cannot be present at the
time of ovum pickup, are recommended to have their semen
frozen for use at the appropriate time
The safety of using frozen sperm has been abundantly proven,
both by experimental work and the actual results in humans.

7. **A semen bank may store a semen preparation for
exclusive use on the donor’s wife . An appropriate
charge may be levied by the bank for the storage
**In the case of non-payment of the charges when the
donor is alive, the bank would have the right to
destroy the semen sample
**All semen banks will require accreditation.

8. Artificial insemination with donor semen (AID)
AID involves placing of donor’s semen obtained
from an accredited ART bank inside the vagina
or the cervix

9. Indications Of AID
1) Non-obstructive azoospermia
2) The husband has a hereditary genetic defect
3) The couple has Rh incompatibility
4) The man has severe oligozoospermia and the
couple does not wish to undergo any of the
sophisticated ART such as ICSI.

10. No treatment should be given without the written
consent of the couple to all the possible stages of
that treatment
A standard consent form recommended by the
accreditation authority should be used by all ART
clinics.
Specific consent must be obtained from couples
who have their gametes frozen , in regard to what
should be done with them if he/she dies.

11. Requirements for sperm Donor
*The age of the donor must not be less than 21 or more than
35 years.
*The individual must be free of HIV and hepatitis B and C infections,
hypertension, diabetes, sexually transmitted diseases.
** The blood group and the Rh status of the individual must be
determined and placed on record.
**Other relevant information in respect of the donor, such as height,
weight, age, educational qualifications, profession, colour of the skin
and the eyes, and the family background in respect of history of any
familial disorder, must be recorded in an appropriate proforma.

12. Questions .
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