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Dhonor ai presentation v2 animated
- 1. AI in the Dhonor Platform: The Donor2Recipients system
- 2. Dhonor.org Platform • Dhonor.org is a collaborative platform to enable safe communication across a host of legacy applications within the Healthcare Arena. • Dhonor’s mission is to improve the lives of patients around the globe. • Dhonor services integrate Blockchain, AI/ML, NFC & RFID technologies.
- 3. AI in Dhonor.org: The Donor2Recipients system • Artificial Intelligence techniques are used to enhance the matching of potential organ donors with many possible registered recipients • The Donor2Recipients (D2R) system: a Distributed AI technology that assesses in real time the best recipients for each available organ, based on the latest data available • Matching based in several criteria including • Donor-recipient compatibility (HLA and infectious diseases) • real time estimation of the transfer times and ischemia times • Estimation of organ decay produced by ischemia
- 4. Main Requirements • Real-time update: System continuously assessing best matches, with the best available data at any moment, • assessment may change if new relevant data is received. • Modularity: system adaptable to different countries and standards. • There will be a Donor2Recipient node instance for each country / transplant region • Explainable AI: any decision made with the system (e.g., why a given recipient is chosen instead of another one) should be explainable, • not only for audit purposes, but also to ensure transparency.
- 5. Main decision criteria Donor2Recipients core module Histocompatibility_Metric DDI_Risk_Estimator Organ_Quality_Estimator Organ_Implantation_Success Time_Estimator Organ_Allocation_Policy Organ_Allocation_Policy Organ_Allocation_Policy Organ_Allocation_Policy Google API Dhonor Data API
- 6. Donor-Recipient Matching • Donor Alarm sent from Dhonor app D2R node D
- 7. Donor-Recipient Matching • D2R assigns closest medical center D2R node D H H H H Google API• Real time transport data from Google • Medical center is warned of arrival
- 8. Donor-Recipient Matching • Dhonor Potential recipients identified and geo-located D R H H H H R R R R R R R R R R R R R R D2R node
- 9. Donor-Recipient Matching • Preselection: Histocompatibility and DDI risk assessment accesing donor’s and recipients’ EHR D R H H H H R R R R R R R R R R R R R R D2R node
- 10. Donor-Recipient Matching • Estimation of transfer times D R H H H H R R R R R R R R R R R R R R D2R node Google API • Recipient to closest medical center • Organ transfer from recipient center to donor center
- 11. Donor-Recipient Matching • Recipient selection (per organ) • Estimation of organ decay due to transfer times • selection based on estimated transplant success D R H H H H R R R R R R R R R R R R R R D2R node Google API
- 12. Donor-Recipient Matching • Recipient match notification • Immediate notification to centers • Notification to recipients only when donor organ quality is assessed D R H H H H R R R R R R R R D2R node
- 13. Donor-Recipient Matching Update • Real-time tracking (donor&recipients) • matching estimators are re-assessed if new relevant data arrives • This may cause (few) organ assignment changes R H H H H R R R D2R node D R R R R R
- 14. • Case 1: donor’s center informs one or several organs are unapropriate for transplant Donor-Recipient Matching Update R H H H H R R R D2R node D R R R R R • Transplant cancellation informed to the recipients’ centers (and patients)
- 15. • Case 2: relevant delay in transfer time for one recipient from estimated time Donor-Recipient Matching Update R H H H H R R R D2R node R R RD Google API• All related estimators recomputed new best recipient match
- 16. • Case 3: Update of donor’s/recipient’s EHR adds relevant new data affecting mathing (e.g., new infection) Donor-Recipient Matching Update R H H H H R R R D2R node D R R R • All related estimators recomputed new best recipient match
- 17. Cross-Borders Donor-Recipient Matching • Only if allowed by the organ allocation policies of the countries/transplant regions. D H H R RR R R R R D2R node D2R node H H RR R • Donor2Recipient matching algorithm distributed among several D2R nodes • D2R nodes coordinate the international organ matching and transfer
- 18. Cross-Borders Donor-Recipient Matching • Network of D2R nodes • Connection based on allowed organ transfers Dhonor D2R Dhonor D2R Dhonor D2R Dhonor D2R Dhonor D2R Dhonor D2R Dhonor D2R Dhonor D2R Dhonor D2R Dhonor D2R Dhonor D2R Dhonor D2R