2. A plane extending from the
sternal angle to the
intervertebral disc between
vertebrae T4 and T5 divide the
mediastinum into:
Superior mediastinum
Inferior mediastinum
The inferior mediastinum
further divided by the
pericardial sac into
Anterior mediastinum
Middle mediastinum
Posterior
mediastinum
Divisions of the mediastinum
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2
2
3. Anterior mediastinum
The area anterior to the
pericardial sac and posterior to
the body of the sternum
Posterior mediastinum
The region posterior to the
pericardial sac and the
diaphragm and anterior to the
bodies of the vertebrae
Middle mediastinum
The area in the middle, which
includes the pericardial sac and
its contents
Subdivisions of the inferior
mediastinum
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3
3
4. The superior
mediastinum
• Is the upper part of the mediastinum
bounded by:
Anteriorly – manubrium sterni
Posteriorly – upper four thoracic vertebrae
Superiorly – thoracic inlet
Inferiorly – plane extending from the
sternal angle to the intervertebral disc
between vertebrae T4 and T5
Contents - Three groups
1- Anterior part (behind the sternum)
Muscles - origin of sternohyoid & sternothyroid mm
venacava and
Gland - thymus gland
Veins - right & left brachiocephallic veins, superior
left sup.intercostal vein
Siyum A
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5. Superior mediastinum …
2. Middle
part
• Arch of aorta & its three
branches – brachiocephalic a, left
common carotid a & left subclavian
a
• Nerves – phrenic & vagi nerves
3. Posterior part (prevertebral)
• Tubes – trachea & esophagus
• Nerve – left recurrent laryngeal
nerve b/n trachea & esophagus
• Lymph nodes & vessel –
paratracheal & tracheobronchial
lymph nodes and thoracic duct
• Muscle – longus colli Don. Siyum
A.
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6. Thymu
s
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Is the most anterior component, posterior
to the manubrium of the sternum
The upper extent of the thymus can reach
into the neck as high as the thyroid gland
A lower portion typically extends
into the anterior mediastinum over
the pericardial sac
The costomediastinal recesses are
on either side
It is a bilobed structure
Large in children, begins to atrophy
after puberty
Mainly fat in the adult with small
islets of active thymic cells scattered
7. Thymus …
Arterial
supply
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From the internal thoracic
arteries
Venous drainage
Into left brachiocephalic
vein and possibly into
internal thoracic veins
Lymphatic drainage
Returns to the following
locations:
Along the internal thoracic
arteries (parasternal)
At the tracheal bifurcation
(tracheobronchial)
8. Vein
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Consists of
Left and right
brachiocephalic vein
Left superior
intercostal vein
Arch of the azygos vein
Superior vena cava
9. Left brachiocephalic vein
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Formation - by left internal
jugular and left subclavian veins
• Posterior to the left
sternoclavicular joint
Course - passes anterior to the
branches of the aortic arch
Termination - joins the right
brachiocephalic vein and form the superior vena cava
Tributaries
The vertebral, first left posterior intercostal vein, left superior
intercostal vein, inferior thyroid, and internal thoracic veins
It may also receive thymic and pericardial veins
10. Right brachiocephalic vein
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Formation - by of the right internal jugular and right subclavian veins
• Posterior to the right sterno clavicular joint
Course - passes down vertically, both vagus and phrenic nerves
descend posterior to the brachiocephalic veins bilaterally
Termination - joins the left brachiocephalic vein to form the
superior vena cava
Tributaries
The vertebral vein
The 1st right posterior
intercostal vein
Internal thoracic veins
Thymic veins
11. Formation
• by 2nd, 3rd and the 4th
posterior intercostal veins
Course
• Over the left side of aortic
arch
🗸 Lateral to the left vagus nerve and medial to the left phrenic nerve
Termination - enters into the left brachiocephalic vein
Tributaries
− the 2nd, 3rd and 4th posterior intercostal veins
− Usually the left bronchial veins
− Sometimes the left pericardiacophrenic vein
Left superior intercostal vein
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12. Superior vena cava
Formation
by the union of the two
brachiocephalic veins
• At the 1st right intercostal
space close to the right
sternal border
Course
Descend down vertically
right phrenic n. runs along with it
Termination
enters the right atrium at the
3rd right costal cartilage level
Tributaries the two brachiocephalic veins and the azygos vein
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13. Arch of the azygos
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Formation - arising from the
posterior aspect of IVC
forms a collateral pathway
between the SVC and IVC
Course - ascends on the right side
of the vertebral column and
arches over the right bronchus
Termination - enters the
posterior aspect of superior vena
cava
at the sternal angel level
Tributaries- posterior intercostal veins
(directly or via hemiazygoses), mediastinal,
esophageal, and bronchial veins
14. Neuro vascular
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1) Aortic arch and its branches
• Brachiocephalic artery
• Left common carotid artery
• Left subclavian artery
2) Nerves:- include
• Left and right vagus nerves
• Left and right phrenic nerves
& cardiac plexus
15. Beginning - the aortic arch
begins at the level of T4/5
or sternal angle behind the
right margin of the
sternum
A continuation of
ascending aorta
Course - extending as high
as the midlevel of the
manubrium of sternum
Termination - it becomes
the descending aorta to
the left of the T4/5
Aortic arch
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16. Aortic arch …
• The inferior aspect of the
aortic arch contains the
ligamentum arteriosum,
vestige of the ductus
arteriosus
The ductus arteriosus
shunted blood from the
pulmonary system in
prenatal life
With expansion of the
lungs and a decrease in
resistance in the
pulmonary arterial system
postnatally, it closes
The ligamentum arteriosum is intimately associated
with the course of the left recuM
rr
en
e
gi
n
stu
t.D
laryngeal nerve
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17. Branches of arch
of aorta
• The branches arise from the superior
aspect of the aortic arch. They are;
Brachiocephalic trunk
Left common carotid
Left subclavian arteries
🗸 They are crossed anteriorly by
the left brachiocephalic vein
Brachiocephalic trunk
• The 1st & largest of the three branches
• Arises posterior to the manubrium
• Divided into right common carotid and right subclavian arteries
posterior to the right sternoclavicular joint
The arteries mainly supply the right side of the head and neck and
the right upper limb, respectively
The thyroid ima artery, occassionally arise from this trunk
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18. Left common
carotid artery
It arises immediately to the left
and slightly posterior to the
brachiocephalic trunk
It then ascends through the
superior mediastinum along the
left side of the trachea
Courses into the head in the
carotid sheath and supplies
the left side of the head and
neck
Left subclavian artery
Arches over the apex of the left lung
posterior to rib I.
Enters the axilla over rib I behind the left
subclavian vein
Branches of the arch of aorta …
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19. They orginate from the
Medulla oblongata as 10th CN
They descend in the neck
In the carotid sheath post. to
the common carotid arteries
and internal jagular veins
Enter the thoracic inlet
posterior to the medial end of
rib 1. Here, they pass
Anterior to the arteries
Posterior to veins
Then, the 2 vagi run posterior to the roots of the lung giving out
branches to the cardiac and pulmonary plexuses.
Vagus
nerves
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20. Left recurrent
laryngeal nerve
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• Branches from the left vagus
• Passes below the ligamentum
arteriosum and the arch of the aorta
• Ascends between the trachea and the
esophagus into the root of the neck
Right recurrent laryngeal nerve?
• Arises from the right vagus anterior to
the right subclavian artery
• Courses around the artery
• Ascends in the neck
🗸Both recurrent nerves provide
vagal innervation to the trachea
and esophagus before
innervating the larynx
21. Arise from anterior rami of C3,4, 5
Enter the thoracic inlet posterior
to the medial end of the clavicle.
Hereafter,
The left phrenic nerve passes
medially & crosses anterior to the
left vagus
The right phrenic nerve lies
lateral to the sup. vena cava
• They descend anterior to the
root of the lungs, between the
lateral wall of the fibrous
pericardium and the mediastinal
pleura
The right phrenic nerve pierces the diaphragm with the inferior vena cava
The left phrenic nerve pierces the diaphragm at the margin of the fibrous
pericardial attachment to the central tendon
Phrenic
nerves
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22. Cardiac
plexus
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• Contains sympathetic,
parasympathetic (vagal)
fibers and visceral
afferents
• Are superficial & deep
Superficial
• Inferior to the aortic
arch and between it
and the pulmonary
trunk
Deep
• Located anterior to the
bifurcation of the
trachea
23. Trachea
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• A membrano/fibro-cartilaginous tube
which forms the upper part of lower
respiratory passage
Situation
Partly in the lower part of the neck
Partly in the superior mediastinum
Beginning
Continuation of larynx from lower
border of cricoid cartilage at C6 level
End
Bifurcates into a right and a left main
bronchus at T4/5 level, at the carina
Length = 10-15cm
24. Cont’d
Oesophagu
s
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• A muscular tube, which forms a portion
of the gastrointestinal tract between
pharynx and stomach
Beginning
• At the pharyngoesophag
D
eia
am
l ju
et
n
ec
rt=
io~
n2ic
n
m
the lower part of the neck at C6 level
Course
• Posterior to the trachea from C7-T4
• Anterior to the vertebral bodies of C7-T8
Termination
• Over left dome of the diaphragm through
esophageal hiatus at T10 level
Length = ~ 25cm
25. Oesophagus …
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• The esophagus normally has 4
constrictions where adjacent structures
produce impressions
🗸 Cervical constriction
• At C6 (pharyngoesophageal junction)
🗸 Thoracic (broncho-aortic) constrictions:
2 constriction
• At T2/3 where crossed by arch of aorta,
• At T4/5 where crossed by left main
bronchus
🗸 Diaphragmatic constriction
• At T10 where it passes through the
esophageal hiatus of the diaphragm,
apprx. 40 cm from the incisor teeth
27. • Is the narrow part of
the Mediastinum
Boundaries
Anteriorly – body of the
sternum
Posteriorly – fibrous
pericardium
Superiorly - an
imaginary plane passing
from the sternal angle to
the intervertebral disc
between vert. T4 and T5
Inferiorly - upper
surface of diaphragm
On each side –
mediastinal pleura
Anterior mediastinum
Contents
Sternopericardial ligaments
Lymph nodes & areolar tissues (in
most of the space)
Some mediastinal branches of
Me
in
n
g
t
is
e
tu
r
.D
nal thoracic arteries
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28. • Is the widest part of the
mediastinum occupied by the
pericardium & its contents
Contents
Heart & its pericardium
Ascending aorta, pulmonary
trunk & its branches
Four pulmonary veins, lower
part of Sup. Venacava, &
azygus vein (terminal part)
Pericardiacophrenic vessels
Phrenic & deep cardiac plexus
Tracheobronchial lymph nodes.
Bifurcation of trachea into right
& left bronchi
Middle
mediastinum
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29. Pericardium and Heart
Pericardium
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• Is a fibroserous sac invaginated by the heart
and great vessels during development
• Has two parts
Outer fibrous & inner double serous
1. Fibrous pericardium - a cone shaped
bag with blunt apex upward continuous
with great vessels
Attachments
Infront – with sternum by sterno pericardial
ligaments
Above – with pre-tracheal layer of deep
cervical fascia
Below - adherent with central tendon of
the diaphragm
Function
Anchorage of heart
Minimizes friction during
action of the heart
30. 2. Serous pericardium - a closed serous sac within fibrous
pericardium enclosing the heart
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Pericardium …
• Consists of two layers
A.Visceral pericardium - lines the surface of the heart –
becomes the outer layer (epicardium)
B.Parietal pericardium - lines the inner surface of fibrous sac
Pericardial cavity is a potential space between the above
two layers contains a fluid called pericardial fluid
(lubricant serous fluid)
31. Pericardial sinuses
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• Are potential spaces formed in the
serous pericardium
• There are two major Pericardial
sinuses
1) Transverse sinus
Is a transversely disposed
space lined by visceral layer of
pericardium
B/n arterial end of primitive heart tube containing pulmonary trunk
& asc.Aorta, and venous end of primitive heart tube enclosing the
six veins (four pulmonary veins & two vena cavae)
2) Oblique sinus
Is a J-shaped cavity of serous pericardium
B/n parietal & visceral pericardium separating the right & left
pulmonary veins as they get into the left atrium
32. Heart
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Location : In the middle mediastinum (enclosed by pericardium)
between the lungs, behind the body of the sternum,
in front of T5-8 and above the diaphragm
• It has the following features
Shape-more or less conical
Situation
• Obliquely placed with ~ 1/3rd of it to the right and
~ 2/3rd of it to the left of the median plane
🗸 Base (superoposteriorly)
🗸 Apex (inferolaterally)
🗸 3-Surfaces, 3-Grooves &
3-layered Wall
🗸 4-Borders, 4-Chambers
A hollow, muscular organ - pump blood
& 4-Major valves
33. The base of
the heart
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• Is the posterior part, directed to the right
• Most fixed part
• Mainly formed by the following structures
2/3rd by the left atrium wit the terminal part
of the 4 pulmonary veins
Partly (1/3rd) by the right atrium
Here, it forms the oblique pericardial sinus
The apex of the heart
• Is the most moveable part
• Formed by tip of left ventricle
• Located in the left 5th intercostal space 9cm from mid s ternal line
34. The base and apex of the heart
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Base - 2/3rd by the left atrium
- 1/3rd by the right atrium
Apex - by the tip of left ventricle
35. Surfaces of the heart
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• Three surfaces
Anterior (sternocostal)
Left (plumonary)
Inferior (diaphragmatic)
1. Anterior (sternocostal) surface
• It is facing to the sternum & costal
cartilages
• Formed by anterior surface of
Right auricle & atrium (small part)
Right ventricle ( 2/3rd )
Left ventricle ( 1/3rd )
• It presents the following features
Anterior part of atrioventricular groove
Anterior interventricular groove
37. 2. Left
surface
Sometimes called the pulmonary
surface
B/c it lies towards the cardiac
impression or notch of the left lung
It presents the left part of
atrioventricular groove
Formed by left auricle &
left ventricle(mainly)
3. Inferior (diaphragmatic) surface
Is the flat surface directed down
ward & backward
Formed by the left ventricle (2/3rd ) &
the right ventricle (1/3rd )
It presents the posterior
interventricular groove
Surfaces of the heart …
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39. Grooves/sulci of the heart
s
e
• Are shallow depressions on the
surface of the heart
• Externally three important grooves
demarcate junctions (septum) of
chambers of the heart
1. Interatrial groove –
demarcat the right & left
atrium
Posteriorly – not well visible
Anteriorly – hidden by the
Aorta & pulmonary trunk
2. Atrioventricular groove – demarcates the two atria above &
the two ventricles below
Anterior part – present in the sternocostal surface mostly towards
the right and it lodges the right coronary artery & small cardiac vein
Posterior part – it forms posterior boundary of the base and it lodges
coronary sinus & anastomoMseinsgisotuf.Dright & left coronary artery
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40. 3. Interventricular groove
• Demarcates the right & left ventricles
Anterior Interventricular groove
• Lies on the sternocostal surface
nearer to the left boarder
downward
• It lodges anterior Interventricular
branch of left coronary artery &
great cardiac vein
Posterior interventricular groove
• Lies on the diaphragmatic surface
• It runs for ward to apex to meet
anterior Interventricular groove
• It contains posterior
Interventricular branch of right
coronary artery & middle cardiac
vein
Grooves/sulci of the heart …
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41. Boarders of the heart
• Four --- Right, inferior, left & superior
boarders
1. Right boarder
• Rounded & convex, extending from
right end of the opening of superior
vena cava to inferior vena cava
• Formed by right atrium
• It separates sternocostal surface
from base of the heart
2. Inferior boarder
• A sharp boarder separating sternocostal from diaphragmatic
surface
• Extends from opening of inferior vena cava to the apex
• Marginal branch of right coronary & corresponding veins run
along this boarder Don. Siyum
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42. 3. Left
boarder
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Boarders of the heart …
• It is a convex ill defined boarder
separating the sternocostal
surface from the left surface
• Formed by left auricle & left
ventricle
• Extends from left auricle to the
apex of the heart
• Marginal branch of left coronary
artery runs along this boarder
4. Superior boarder
• Is the upper boarder where the great vessels enter & leave the heart
• Formed by the right & left auricles with the conical portion of right
ventricle (infundibulum)
43. s
Wall and chambers of
the Heart
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Wall of the heart
Structurally it is composed of three layer
1.Epicardium – the outer wall derived
from visceral serous pericardium
2. Myocardium – is the middle muscular
layer responsible for pumping action
3.Endocardium – is the inner epithelial
layer continuous with the epithelium of
the great vessels
Chambers of the heart
• Its interior has four chambers separated by septum
Two atria - receiving chamber
Two ventricles - pumping chambers
44. Chambers of the heart …
🗸 2 receiving
chambers
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Right atrium
Left atrium
🗸 2 pumping chambers
Right ventricle
Left ventricle
45. Right atrium /RA
Forms the right margin of the heart
with the right auricle projecting
superiorly and anteriorly
The interior of the right atrium is
divided by the crista terminalis into
anterior & posterior parts
The anterior part has a ridge area
with musculi pectinati
(pectinate muscles) capable of
contraction
The posterior is smooth where
great vessels open into the RA &
has openings of the;
1. Superior vena cava
2. Inferior vena cava
3. Coronary sinus
4. Right atrioventricular
opening
Chambers …
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On the interatrial wall superior to the
opening of the inferior vena cava
there is a depression area, the fossa
ovalis
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46. Left
atrium
• Forms 2/3 of base of heart
The auricle is visible
anteriorly from the left side
of the pulmonary trunk
• Lies superior to the coronary
sulcus
• The interior of the left atrium
presents the following features
Smooth posterior part
⚫ Has 4 openings of pulmonary veins & one left atrioventricular opening
Rough anterior part
⚫ Has musculi pectinati (pectinate muscles) capable of contraction
⚫ It is an opening of communication b/n left atrium & left ventricle
Chambers …
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47. Ventricles
The right ventricle / RV
• Forms most of the anterior
(sternocostal) & small inferior surface
of the heart and the inferior margin
• The interior of the right ventricle
consists of two parts - Rough &
smooth
1) Rough or inflowing part – is the
ventricle proper continuous with right
atrium & receive blood from RA
• It is lined with trabeculae carnae
(contractile tissue)
Some form papillary muscles which
arise from the anterior and posterior
walls
The right ventricle also has septal
papillary muscles (3rd) Don. Siyum
A.
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48. The apex of the above papillary muscles
are attached to the cusp of right
atrioventricular (tricuspid) valve by the
chordae tendinae (thread like
tendinous cord)
The three papillary muscle groups
attached to the three cusps pull the
cusps down to the R.ventricle during
ventricular systole
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49. The portion of out flow continuous with the pulmonary trunk
The pulmonary orifies located at the apex of the infundibulum
is guarded by a valve which has three cusps (right, left &
anterior)
2) Infundibulum or
smooth part
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50. Aortic vestibule
Inflowing
part
• The interior of the LV has 2 parts
1. Rough (inflowing) part
ventricle
(LV)
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• Is lined with trabeculae carnae
(ridges) from which the papillary
muscles arising from anterior &
posterior walls
Two papillary muscles are present
They are anterior & posterior
Attached to both cusps of the mitral
(bicuspid) valve by cordae tendinae
• It forms
The apex
1/3rd of the sternocostal surface
Most of the left boarder & surface
2/3rd of the diaphragmatic surface
51. The left ventricle …
Aortic vestibule
2.The smooth (out
flow) part
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• The out flow part known as
aortic vestibule
• Is just below & continuous with
the aortic orifice
The aortic orifice is at the
beginning of the ascending
aorta guarded by aortic valve
which has three cusps (right,
left & posterior)
Three dilatations/sinuses
(aortic) are present
above the cusps which give
origin to coronary arteries
(they supply the heart)
52. The difference between the two ventricles
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• Thickness of the wall:- the
left ventricle is about 5 times
thicker than the right
Because more work is
done by the left than the
right
The right pump blood
to lungs where as the
left is to whole body
53. Valves of the Heart
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Tricuspid Valve: Right AV valve
• Has 3 cusps made of endocardium & CT
• The cusps anchored in the Rt. Ventricle
by Chordae Tendinae
Prevent eversion of cusps into atrium
• Flow of blood pushes the cusps open
Bicuspid (mitral) valve: left AV valve
• Has 2 cusps anchored in left ventricle
by chordae tendinae
• Functions in the same way as R.AV valve
🗸They, both AV valves, close together
54. Semilunar Valves
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Pulmonary Semilunar Valve
🗸Between RV & pulmonary trunk
Aortic Semilunar Valve
🗸Between LV & ascending aorta
• They are made of 3 cusps
(have no tendinous cords)
• Prevent backflow of blood
from large arteries to the
ventricles
• As blood leaves the ventricle
The cusps are pushed up
into the artery & project
toward its walls
55. Surface Anatomy of Heart Valves
• Pulmonary valve lies behind the
medial end of 3rd left costal
cartilage and adjoining part of
sternum
• Aortic valve lies behind the left half
of sternum in the 3rd intercostal
space.
• Mitral valve lies behind the left half
of sternum in the 4th costal
cartilage.
• Tricuspid valve lies behind the right
half of sternum behind the fourth
intercostal space.
55
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57. Pulmonary semilunar valve - 2nd I.C.S of left sternal margin
Aortic semilunar valve - 2nd I.C.S right sternal margin
Mitral valve - 5th intercostal space (I.C.S) at the apex
Tricuspid valve –right 5th I.C.S of right sternal margin
57
The sounds can be heard(auscultated) at the following points :
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58. • The heart is supplied by two
arteries
The right and left coronary
arteries
• They are branches of the
ascending aorta, arise from;
The right and left coronary
sinuses of the aortic valves
respectively
Blood supply of
the heart
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60. • RCA runs in the coronary
sulcus b/n the right atrium
and right ventricle anteriorly
• Over the right margin, gives
off a right marginal branch
Supplies the right ventricle
Coronary arteries …
At the junction of the septum and the four chambers, it gives rise to a nodal
branch, which supplies the AV node & to this area of the R. atrium
• Finally, RCA terminates in the posterior interventricular sulcus as the
posterior interventricular artery, supplying mainly
The posterior aspect of the right and left ventricles as well as the posterior
1/2 of the interventricular septum
Nodal
Marginal
Post. Interventricular
Right coronary artery (RCA)
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61. left coronary
artery (LCA)
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• Passes anteriorly between
the pulmonary trunk and
the tip of the auricle of the
left atrium.
• It divides on the anterior
aspect of the heart into
Anterior interventricular
branch
Circumflex branch
Coronary arteries …
62. 1. Anterior
interventricular branch
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• Descends in the anterior interventricular
sulcus to the inferior margin of the heart
• Continues into the posterior interventricular
sulcus on the diaphragmatic surface
It supplies anterior aspects of the
right and left ventricles, and anterior
1/2 of the interventricular septum
2. Circumflex branch
• Runs to the left in the atrioventricular
sulcus b/n the left atrium and ventricle
It gives off a marginal branch for the lateral margin of the left ventricle
and continues onto the posterior aspect of the heart
It forms an anastomosis with the arteries derived from the right
coronary artery in the posterior interventricular sulcus
Coronary arteries …
63. the heart and the
• Accompany coronary arteries
and their branches
• Lie superficial to the arteries in
the sulci
Most of the veins drain into the coronary sinus
The coronary sinus
• Lies in the coronary sulcus between the left margin of
posterior interventricular sulcus
• It drains into the right atrium by an opening to the left of the entrance of
the inferior vena cava
The heart is drained by
Three major veins
Other small veins
Cardiac veins
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64. ium
A. Great cardiac vein
• Formed in the anterior interventricular sulcus
Left marginal vein is a tributary of the great cardiac vein
• Joins the coronary sinus near the left margin of the heart
• Drains the area of the heart supplied by left coronary a.
B. Middle cardiac vein
• It occupies the posterior interventricular sulcus
• Enters coronary sinus near the entrance to the right atr
C. Small cardiac vein
• Follows the right marginal branch of the right coronary a
• Joins the coronary sinus near the junction with the middle cardiac
vein at the left of the right atrium posterorly
The middle & small cardiac veins drains the area of the
heart supplied by right coronary a
The three major veins
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66. Other small veins
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Oblique vein
• Drains the left atrium and merges
with the great cardiac vein to form
the coronary sinus (left posterior
ventricular vein also join them??)
Anterior cardiac veins
• Drain the anterior surface of the
right ventricle
• Open directly into the right atrium
Venae cordis minimae
• Are tiny veins draining the heart wall & open directly into the chambers
• Although called veins, they are valveless & may carry blood from the
heart chambers to the myocardium.
67. Lymphatic Drainage of the Heart
• Lymphatic vessels in the myocardium
and subendocardial connective tissue
pass to the subepicardial lymphatic
plexus
Vessels from this plexus pass to
the coronary groove and follow
the coronary arteries
A lymphatic vessel, formed by the union
of various vessels from the heart
Ascends between the pulmonary
trunk and the left atrium
Ends in the inferior
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68. • The heart has specialized
junctional ‟myocytes” concerned
for origin & propagation of heart
beat.
There by coordinate the
contractions of the four
chambers. They are -
1) The sinoatrial (SA) node
Is the pacemaker of the heart
Located b/n right auricle &
Sup.venacava in the RA
Is vascularized by the nodal branch of the right coronary artery
Conduction system of the heart
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69. 2) The Atrioventricular
(AV) node
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Conduction system …
• Is a smaller collection of nodal tissue
• Located in the right atrium, postero
inferior region of the interatrial
septum anterior to the mouth of the
coronary sinus.
• Receives impulse from SA node &
passes to AV bundle
3) The Atrioventricular (AV)
bundle /bundle of His/
• Connects atria to ventricle in the
interventricular septum
• Divides into right and left bundle
branches (crura) at the junction of
the membranous and muscular
parts of the interventricular septum
70. Conduction system …
4) Purkinje’s
cells
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• Subendothelial plexus consists of straited fibers
71. • By autonomic nerve fibers from
superficial & deep cardiac
plexuses
Superficial plexus - lies
anteroinferior to the aortic arch
Between the aortic arch &
pulmonary trunk
Deep plexus - posteroinferior to
the aortic arch
Between the aortic arch & the
tracheal bifurcation
• The plexuses contain;
1. Sympathetic
2. Parasympathetic
3. Visceral afferent (sensory)
Innervations of the heart
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72. Innervations …
1.Sympathetic - is via cardiac
branches of the cervical and upper thoracic
portions of the sympathetic trunks
Cervical cardiac nerves - from superior
(C1-4) and middle (C5&6) cervical ganglia
Cervicothoracic (inferior) cardiac nerve -
from stellate (cervicothoracic) ganglion
(C7-T1)
Thoracic branches - from T2-4/5 sym. trunk
2.Parasympathetic - … via Vagus
Both the sympathetic and parasympathetic
branch and fuse - cardiac plexus
A cardiac plexus courses around the right
pulmonary artery to the posterior aspect of
the atria
They distribute to the SA node, AV node & to
the coronary arteries Don. Siyum
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74. Other structures in the middle
mediastinum
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Arteries
Ascending aorta
pulmonary trunk
Veins
Four pulmonary veins
Lower part of sup. Venacava
Terminal part of azygus vein
Nerves
Phrenic & deep cardiac plexus
Lymph nodes- Tracheobronchial nodes
75. Contents of the posterior mediastinum
• Tube – Oesophagus with oesophageal
nerve plexus
• Arteries – Descending thoracic aorta
& its branches
• Veins – Azygos, hemiazygos,
accessory hemiazygos and
posterior intercostal veins
• Nerves – Vagus &
Sympathetic trunks and
splanchnic nerves
• Lymph vessels &nodes –
Thoracic duct & posterior
mediastinal lymph node
Posterior mediastinum
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77. Descending
aorta
• From the left side of the body of T5,
descends on the left of the vertebral
column posterior to the root of the
left lung
• Passes through the aortic hiatus at
T12
• The greater splanchnic nerve from
the sympathetic trunk joins the
descending aorta and enters the
abdomen with it
•The visceral branches of the
descending aorta are
Bronchial arteries (left)
Esophageal arteries
Branches to pericardium and diaphragm …
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79. • The right and left posterior
intercostal arteries from the 3rd
intercostal space to the subcostal
arteries
• The right posterior intercostal
arteries from T3-T8 cross the
vertebral column anterior to the
vertebrae
They anastomose with the anterior
intercostal arteries of the internal
thoracic artery
• The 1st and 2nd intercostal spaces
are supplied by the costocervical
trunk of the subclavian arteries
The parietal (thoracic)
branches are
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Descending aorta …
80. Azygos vein
Drain the posterior thoracic wall and
upper lumbar region
Connects superior and inferior venae
The azygos & Hemiazygos
venous systems
• cavae
Originate in the abdomen by union of lumbar azygos, right ascending
lumbar and right subcostal veins
• Course
Enter thoracic cavity through aortic opening or pierce right crus of
diaphragm
ascends on the right side of the vertebral column and to enter the
posterior aspect of the superior vena cava at the level of T4.
80
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81. Tributaries
1. Right superior intercostal vein
2. Right 5 – 11 intercostal veins
3. Right sub costal vein and right
ascending lumbar
4. Right bronchial vein
5. Esophageal, Mediastinal &
pericardial veins
6. Hemiazygos vein
7. Accessory hemiazygos azygos
vein
81
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82. Hemiazgos vein
Origin
In the abdomen by union of left
ascending lumbar and left
subcostal
Course
Enter thoracic cavity piercing the
left crus of diaphragm at T9
crosses to the right behind
thoracic aorta, esophagus &
thoracic duct end in azygos
vein
Tributaries
1. 9th – 11th left intercostal
2. Left subcostal
3. Left ascending lumbar
82
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83. Accessory hemiazygos vein
Originate at medial end of 4th and 5th
intercostal space on the left of the
vertebral column.
Crosses to the right at T8 behind
aorta, esophagus and join azygos
vein.
Tributaries
Left 5th - 8th intercostal veins
Left bronchial vein
83
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84. Thoracic duct
Largest lymphatic vessel
Begins at the cisterna chyli,
posterior to the abdominal
aorta, inferior to the
diaphragm
Enters the thorax posterior
to the descending aorta
Ascends on the right of the
vertebral column
At T5 cross to left side
Terminating at the junction
between the left subclavian
and left internal jugular
veins
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85. Thoracic duct
• The thoracic duct thus conveys to the blood
all lymph from the lower limbs, pelvic cavity,
abdominal cavity, left side of the thorax, and
left side of the head, neck, and left armDon.Siyum
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86. 86
Tributaries
• Posterior mediastinal nodes
• Intercostal nodes
• Left jugular trunk
• Left subclavian trunk
• Left mediastinal trunk
• It drains all the lymph of the
body except for the right
thorax, right upper limb and
right side of the head and neck.
• These remaining areas drain
into the right lymphatic duct
which joins the junction of the
right internal jugular and
right subclavian veins
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87. Vagus nerves
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• Inferior to the root of the lung, the
left vagus lies anterior to the
esophagus and the right vagus lies
posteriorly
Their branches form the anterior
and posterior esophageal
plexuses
• They form single nerves to pierce the
diaphragm at the esophageal hiatus
• Below the diaphragm they are
renamed as the anterior and
posterior gastric nerves
• Vagal branches induce peristalsis
in the esophagus and are
secretomotor to mucous glands
88. Sympathetic trunks
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• The symathetic trunk and
their associated ganglia form a
major portion of the ANS
• The thoracic sympathetic trunks
are in continuity with the
cervical and lumbar
sympathetic trunks
• The thoracic sympathetic trunks
lie against
The heads of the ribs in
the superior part of the
thorax
The costovertebral
joints in the midthoracic
level
The sides of vertebral
bodies in the lower part
of the thorax
89. This sympathetic trunks consists of
two parallel cords punctuated by
11 or 12 ganglia
Two types of medial branches
are given off by the ganglia
The first type includes branches
from the upper four/five
ganglia
The second type includes
branches from the lower eight
/seven ganglia
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91. Sympathetic …
The first type, from the upper four/five
ganglia
Consists mainly of postganglionic
sympathetic fibers, which supply the
various thoracic viscera
These branches are relatively
small, also contain visceral
afferent fibers
The second type, from the lower
eight/seven ganglia
Consists mainly of preganglionic
sympathetic fibers, which supply the
various abdominal and pelvic
viscera
Form the 3 thoracic splanchnic
nerves greater, lesser, and least
splanchnic nerves
These branches are large, also carry
visceral afferent fibers Don. Siyum
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92. Sympathetic …
• Solid lines indicate
pre-ganglionic axons
while broken lines
indicate post-
ganglionic axons
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93. The splanchnic nerves → Greater, lesser and least
• The lower thoracic splanchnic nerves, also known as greater, lesser,
and least splanchnic nerves, are part of the abdominopelvic
splanchnic nerves
Because they supply viscera
inferior to the diaphragm
• They consist of presynaptic fibers
from the 5/6th to 12th
sympathetic ganglia, which pass
through the diaphragm
They synapse in prevertebral
ganglia in the abdomen
Greater splanchnic nerve
• On each side usually arises from the 5th - 9th/10th thoracic ganglia
• It descends across the vertebral bodies moving in a medial
direction, passes into the abdomen through the crus of the
diaphragm, and ends in the cM
ee
ln
ig
ais
t
cu.D
ganglion
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94. The splanchnic nerves …
• Usually arises from tenth and
eleventh thoracic ganglia
It descends across the
vertebral bodies moving in
a medial direction, and
passes into the abdomen
through the crus of the
diaphragm to end in the
aorticorenal ganglion
Least splanchnic nerve
• Usually arises from the twelfth thoracic ganglion
It descends and passes into the abdomen through the crus of the
diaphragm to end in the aorticorenal plexus
Lesser splanchnic nerve
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