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NETHRADHAM
Super Speciality Eye Hospital
NETHRADHAMA
Super Speciality Eye Hospital
Dr.SMITH SNEHAL SUTE
Fellow- Phaco & Refractive Surgery
INTRODUCTION
• Multiple needles, tips, instruments, and devices enter and leave the anterior
chamber during cataract surgery.
• Introduction of the IOL into the capsular bag- an important step
• Each step of cataract surgery has evolved over the decades.
• The place of lens holding and folding forceps is being taken by myriad IOL
insertion systems.
• Sir Harold Ridley introduced the first IOL in 1949.
• Charles D. Kelman MD introduced phacoemulsification,
- led to the era of small-incision cataract surgery.
• Thomas R. Mazzocco MD, developed the first foldable IOL in
1980.
- allowed lens insertion without enlargement of the 3-mm
phaco wound
INTRODUCTION
IOL
DEPLOYMENT
Preloaded
injectors
Manual loading in
cartridge
Microbial safety
Mechanical loading
Surgical time
Reproducibilty
Plunger
mechanism
Screw
mechanism
1 handed
delivery
Less controlled
2 handed
delivery
Controlled
• Additional steps to load and prime
the IOL
• More number of errors
• Longer training for the operating
room staff
• Increased time of surgery.
PROBLEMS with Manual Injection Systems
• Contamination
Wang L, Wolfe AP, Paliwal CS. IOL delivery performance of
three IOL preloaded delivery systems XXXIII Congress of the
ESCRS 2015, ESCRS Official Website.
• Foreign-body
introduction
• Inadequate
cleaning
• Postoperative endophthalmitis
• Deposits on IOL surface:-
• shape of the cartridge or nozzle
• linear deposits
• hexagonal-shaped cartridges
rather than round.
Kleinmann G, Marcovich AL, Apple DJ, Mamalis N. Linear
deposits on the surfaces of intraocular lenses implanted
through a hexagonal cartridge which mimic
scratches/cracks on the lenses. Br J Ophthalmol 2005;
89:1474–1477
Cartridge Complications
• Cartridge cracking:-
• friction during the transit through
the injector nozzle.
Singh AD, Fang T, Rath R. Cartridge cracks during foldable
intraocular lens insertion. J Cataract Refract Surg. 1998
Sep;24(9):1220-2. doi: 10.1016/s0886-3350(98)80015-1.
PMID: 9768396.

X
• Surgically induced astigmatism:-
• Creating an incision necessary for
the removal of cataracts and IOL
implantation
• varying degrees of surgically
induced astigmatism.
• type of injector cartridge or
insertion method used,
Cartridge Complications
Wound stress- greatest
when the IOL passed
through the incision.
• Corneal wound is like a slit
• IOL cartridges are like a cylinder
(oval or circular in section).
• Thus, by the law of physics,
insertion of a cylinder through a
slit would always lead to some
stretch or damage to the slit
architecture
Cartridge Complications
• Smaller diameter injector
nozzles
hamper the ease of IOL insertion
• Reducing the thickness of the
nozzle or designing a slit in the
nozzle to buffer the stretch force
would be a good compromise
• Manual holding, folding, and insertion techniques have, in recent years,
been largely replaced by the use of novel IOL injection systems.
PRELOADED INJECTORS
 Pre-packaged
 Ready-to-insert
 Preloaded IOL
adopted by many manufacturers.
 Simple
 Safe
 Effective devices
IOL implantation through a
relatively small incision
iSert
(Hoya)
AcrySert C
(Alcon)
Tecnis
iTec (J&J)
BLIS
(Bausch
+ Lomb
Injector
System)
AutonoMe
(Alcon)
PRELOADEDINJECTORS
 One step, ready to insert
 Optimized design for small incision size
 Smooth passage of the IOL
 No risk of damage to haptic or optic
 Smooth folding and unfolding of the haptic
 Convenient and cost effective use
CHARACTERISITCS OF AN IDEAL
PRELOADED INJECTOR
• Implantation through smaller
incision
• Shorter duration of wound
healing,
faster recovery
• Microbiologic safety
Kokuzawa S, Suemori S, Mochizuki K, Hirose Y, Yaguchi
T. Aspergillus tubingenesis endophthalmitis after cataract
surgery with implantation of preloaded intraocular lens. Semin
Ophthalmol 2014; 29(4): 218-21.
Advantages of Preloaded Injectors
• IOL is already loaded instill
(OVD) ready for insertion.
• Avoids potential mistakes such as
loading the lens incorrectly
• Enhanced surgical outcomes
deployed directly from the
manufacturer to the eye,
minimizing the risk for IOL damage
through handling
• Intraoperative aberrometry
• BLUEJECT
• BLUEMIXS® 180
• MONARCH III
• AutonoMe
• UNFOLDER Platinum
• UNFOLDER Emerald
• INJ 100
B+L J&J
ZEISS
Alcon
IOL
Implantation
systems
Injectors
Cartridg
es
Injectors
• Hand piece – Titanium alloy material - reusable
• Y-tip plunger rod assists in lens manipulation
• Cartridge lock allows for secure loading in the correct position
• Lens injecting mechanism : Screw-style insertion
• Incision size : 2.2- 2.8mm
• Sterilization - Flash autoclave or steam sterilization
Cartridg
es
Incision size
2.2
2.8
2.8
UNFOLDER Platinum series & 1VIPR30
Designed for
Tecnis 1 Monofocal
Tecnis Toric
Tecnis MF(multifocal)
Tecnis MF Toric
Tecnis Symfony (EDOF)
Tecnis Synergy
UNFOLDER Emerald series & EmeraldC30
Designed for
Tecnis 3 piece
Sensar 3 piece
UNFOLDER
Platinum series DK 7796
UNFOLDER
Emerald series T/ XL
Injectors
Cartridg
es
1MTEC30 Emerald C
1VIPR30
Tecnis 3 piece
Sensar 3 piece
Tecnis Toric
Tecnis MF Toric
Tecnis 1
Tecnis MF
Tecnis Symfony Tecnis Synergy
• Syringe type systems
• 1.8 mm incision
• Large loading chamber
Preloade
d &
Disposabl
e
• 2.0
Injector
• 2.2
Injector
• 2.4
Injector
• Blueject2.0
(+4.0 to +24.0 D)
• Blueject2.2
(+24.5 to +30.0 D)
• Blueject2.4
(+30.5 to +34.0 D)
• Large loading chamber
• Unrestricted access for IOL loading
• Safety ontrolled and linear
injection
• For a wide variety of hydrophilic
ZEISS MICS IOLs
Preloade
d
Blueject
Designed for
CT® Lucia 611P/
611PY
CT® Lucia 211P
Blueject
Designed for
CT® Lucia 611P/
611PY
CT® Lucia 211P
Bluemixs® 180
Designed for
AT LARA® 829 MP
AT LISA® Tri 839 MP
AT LISA® 809 MP
909 M
CT ASPHINA
409 MP/ 509 MP
AT Torbi 709 MP
Bluemixs® 180
Designed for
AT LARA® 829 MP
AT LISA® Tri 839 MP
AT LISA® 809 MP
909 M
CT ASPHINA
409 MP/ 509 MP
AT Torbi 709 MP
Monarch® II
• “C” cartridge
• 2.4 mm incision
• “C” cartridge
• 2.4 mm incision: through the
wound
• “D” cartridge: smaller
• 2.2 mm incision: wound assisted
smaller plunger tip
Monarch ® III
IOL INJECTORSFOR Monarch® SYSTEMS
Screw thread injector
MONARCH IIB, IIIC IIID
Monarch® II
• “C” cartridge
• 2.4 mm
• “D” cartridge:
• 2.2 mm
Monarch ® III
33%
B C D
“B” Cartridge
• Incision size :
3mm
• All 3 Piece IOLs
• Special order
Single
pieceIOLs
(+35 to + 40 D)
“C” Cartridge
• Incision size : 2.4mm
• All Single Piece IOLs ( +6 to +34 D)
“D” Cartridge
• Incision size :
2.2mm
• THIN Single
Piece IOLs
(+6 to +26 D)
Big Compact Dimunitive
Monarch®III &C Cartridge
Designed for
ACRYSOF
Monarch®III &D Cartridge
Designed for
ACRYSOF IQ
PanOptix/ Toric
AutonoMe Device
AutonoMe Device
AutonoMe Device
Designed for
CLAREON
AutonoMe Device
Designed for
CLAREON
BLIS (Bausch+Lomb Injector
System)
Designed for
enVista
COMPLICATIONS
 Trapped trailing haptic
 Haptic optic adhesion
 Misdirected leading haptic
 Twisted haptic
 Overriding plunger
 Trauma to IOL: damage to IOL haptic/optic:
COMPLICATIONS
 Damage to IOL haptic/optic:
 poor IOL injector design and packaging
Nguyen DQ, Saleh TA, Pandey SK, Bates AK. Irregularities on the surface of single-piece AcrySof SA60ATintraocular lenses.
J Cataract Refract Surg 2006;32(3):495–498
 Inappropriate manual handling and loading,
Vrabec MP, Syverud JC, Burgess CJ. Forceps-induced scratching of a foldable acrylic intraocular lens.
Arch Ophthalmol1996;114(6):777
 Overriding injector plungers,
 Friction during IOL passage through the injector nozzle
- type of viscoelastic medium used for loading and IOL injection
Myers TD, Olson RJ. Comparison of the effects of viscoelastic agents on clinical properties of the unfolder
lens injection system. J Cataract Refract Surg 1999;25(7):953–958
INJECTOR
CARTRIDGE
Systems
Alcon
B+L
ZEISS
J&J
UNFOLDER
Platinum
UNFOLDER
Emerald
1MTEC30 EMERALDC
1VIPR30
Monarch III AutonoMe™
D cartridge Device
BLIS INJ100
BLUEJECT™ BLUEMIXS®180
• IOL manufacturers are keenly working on the development of better
preloaded IOL delivery systems.
• The focus is on making IOL size, design, and thickness more compatible with
the disposable plunger and cartridge assembly.
• In the near future, all IOL implantations will be performed through preloaded
IOL delivery systems.
• The healthy competition among manufacturers to achieve the best system
will not only provide us with flawless IOL delivery but will also make these
products more cost-effective
• Foldable IOLs have helped alter the face of cataract surgery by improving
healing time, limiting complications and making phacoemulsification the
standard procedure over extracapsular surgery, all in the span of 3 decades
• Advancements in cataract surgery have necessitated the availability of
intraocular lens preloaded delivery systems that can safely, effectively and
predictably deliver IOLs in the eye.
• Preloaded delivery systems simplify and reduce procedural variability
during surgery preparation.
Clearly, cataract surgery continues to improve
in all areas, with a bright future for improved
vision and a happy patient.
Vision
Leadership in the Eye Care Domain
Mission
Vision Care Par Excellence
smithsnehalsute@yahoo.com

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IOLCatridge-Injector Systems

  • 1. NETHRADHAM Super Speciality Eye Hospital NETHRADHAMA Super Speciality Eye Hospital Dr.SMITH SNEHAL SUTE Fellow- Phaco & Refractive Surgery
  • 2. INTRODUCTION • Multiple needles, tips, instruments, and devices enter and leave the anterior chamber during cataract surgery. • Introduction of the IOL into the capsular bag- an important step • Each step of cataract surgery has evolved over the decades. • The place of lens holding and folding forceps is being taken by myriad IOL insertion systems.
  • 3. • Sir Harold Ridley introduced the first IOL in 1949. • Charles D. Kelman MD introduced phacoemulsification, - led to the era of small-incision cataract surgery. • Thomas R. Mazzocco MD, developed the first foldable IOL in 1980. - allowed lens insertion without enlargement of the 3-mm phaco wound INTRODUCTION
  • 4. IOL DEPLOYMENT Preloaded injectors Manual loading in cartridge Microbial safety Mechanical loading Surgical time Reproducibilty Plunger mechanism Screw mechanism 1 handed delivery Less controlled 2 handed delivery Controlled
  • 5. • Additional steps to load and prime the IOL • More number of errors • Longer training for the operating room staff • Increased time of surgery. PROBLEMS with Manual Injection Systems • Contamination Wang L, Wolfe AP, Paliwal CS. IOL delivery performance of three IOL preloaded delivery systems XXXIII Congress of the ESCRS 2015, ESCRS Official Website. • Foreign-body introduction • Inadequate cleaning • Postoperative endophthalmitis
  • 6. • Deposits on IOL surface:- • shape of the cartridge or nozzle • linear deposits • hexagonal-shaped cartridges rather than round. Kleinmann G, Marcovich AL, Apple DJ, Mamalis N. Linear deposits on the surfaces of intraocular lenses implanted through a hexagonal cartridge which mimic scratches/cracks on the lenses. Br J Ophthalmol 2005; 89:1474–1477 Cartridge Complications • Cartridge cracking:- • friction during the transit through the injector nozzle. Singh AD, Fang T, Rath R. Cartridge cracks during foldable intraocular lens insertion. J Cataract Refract Surg. 1998 Sep;24(9):1220-2. doi: 10.1016/s0886-3350(98)80015-1. PMID: 9768396.  X
  • 7. • Surgically induced astigmatism:- • Creating an incision necessary for the removal of cataracts and IOL implantation • varying degrees of surgically induced astigmatism. • type of injector cartridge or insertion method used, Cartridge Complications Wound stress- greatest when the IOL passed through the incision.
  • 8. • Corneal wound is like a slit • IOL cartridges are like a cylinder (oval or circular in section). • Thus, by the law of physics, insertion of a cylinder through a slit would always lead to some stretch or damage to the slit architecture Cartridge Complications • Smaller diameter injector nozzles hamper the ease of IOL insertion • Reducing the thickness of the nozzle or designing a slit in the nozzle to buffer the stretch force would be a good compromise
  • 9.
  • 10. • Manual holding, folding, and insertion techniques have, in recent years, been largely replaced by the use of novel IOL injection systems. PRELOADED INJECTORS  Pre-packaged  Ready-to-insert  Preloaded IOL adopted by many manufacturers.  Simple  Safe  Effective devices IOL implantation through a relatively small incision
  • 11. iSert (Hoya) AcrySert C (Alcon) Tecnis iTec (J&J) BLIS (Bausch + Lomb Injector System) AutonoMe (Alcon) PRELOADEDINJECTORS
  • 12.  One step, ready to insert  Optimized design for small incision size  Smooth passage of the IOL  No risk of damage to haptic or optic  Smooth folding and unfolding of the haptic  Convenient and cost effective use CHARACTERISITCS OF AN IDEAL PRELOADED INJECTOR
  • 13. • Implantation through smaller incision • Shorter duration of wound healing, faster recovery • Microbiologic safety Kokuzawa S, Suemori S, Mochizuki K, Hirose Y, Yaguchi T. Aspergillus tubingenesis endophthalmitis after cataract surgery with implantation of preloaded intraocular lens. Semin Ophthalmol 2014; 29(4): 218-21. Advantages of Preloaded Injectors • IOL is already loaded instill (OVD) ready for insertion. • Avoids potential mistakes such as loading the lens incorrectly • Enhanced surgical outcomes deployed directly from the manufacturer to the eye, minimizing the risk for IOL damage through handling • Intraoperative aberrometry
  • 14.
  • 15. • BLUEJECT • BLUEMIXS® 180 • MONARCH III • AutonoMe • UNFOLDER Platinum • UNFOLDER Emerald • INJ 100 B+L J&J ZEISS Alcon IOL Implantation systems
  • 17. Injectors • Hand piece – Titanium alloy material - reusable • Y-tip plunger rod assists in lens manipulation • Cartridge lock allows for secure loading in the correct position • Lens injecting mechanism : Screw-style insertion • Incision size : 2.2- 2.8mm • Sterilization - Flash autoclave or steam sterilization
  • 19. UNFOLDER Platinum series & 1VIPR30 Designed for Tecnis 1 Monofocal Tecnis Toric Tecnis MF(multifocal) Tecnis MF Toric Tecnis Symfony (EDOF) Tecnis Synergy
  • 20. UNFOLDER Emerald series & EmeraldC30 Designed for Tecnis 3 piece Sensar 3 piece
  • 21. UNFOLDER Platinum series DK 7796 UNFOLDER Emerald series T/ XL Injectors Cartridg es 1MTEC30 Emerald C 1VIPR30 Tecnis 3 piece Sensar 3 piece Tecnis Toric Tecnis MF Toric Tecnis 1 Tecnis MF Tecnis Symfony Tecnis Synergy
  • 22. • Syringe type systems • 1.8 mm incision • Large loading chamber Preloade d & Disposabl e • 2.0 Injector • 2.2 Injector • 2.4 Injector
  • 23. • Blueject2.0 (+4.0 to +24.0 D) • Blueject2.2 (+24.5 to +30.0 D) • Blueject2.4 (+30.5 to +34.0 D) • Large loading chamber • Unrestricted access for IOL loading • Safety ontrolled and linear injection • For a wide variety of hydrophilic ZEISS MICS IOLs Preloade d
  • 24. Blueject Designed for CT® Lucia 611P/ 611PY CT® Lucia 211P
  • 25. Blueject Designed for CT® Lucia 611P/ 611PY CT® Lucia 211P
  • 26. Bluemixs® 180 Designed for AT LARA® 829 MP AT LISA® Tri 839 MP AT LISA® 809 MP 909 M CT ASPHINA 409 MP/ 509 MP AT Torbi 709 MP
  • 27. Bluemixs® 180 Designed for AT LARA® 829 MP AT LISA® Tri 839 MP AT LISA® 809 MP 909 M CT ASPHINA 409 MP/ 509 MP AT Torbi 709 MP
  • 28.
  • 29. Monarch® II • “C” cartridge • 2.4 mm incision • “C” cartridge • 2.4 mm incision: through the wound • “D” cartridge: smaller • 2.2 mm incision: wound assisted smaller plunger tip Monarch ® III
  • 30. IOL INJECTORSFOR Monarch® SYSTEMS Screw thread injector MONARCH IIB, IIIC IIID
  • 31. Monarch® II • “C” cartridge • 2.4 mm • “D” cartridge: • 2.2 mm Monarch ® III 33%
  • 32.
  • 33. B C D “B” Cartridge • Incision size : 3mm • All 3 Piece IOLs • Special order Single pieceIOLs (+35 to + 40 D) “C” Cartridge • Incision size : 2.4mm • All Single Piece IOLs ( +6 to +34 D) “D” Cartridge • Incision size : 2.2mm • THIN Single Piece IOLs (+6 to +26 D) Big Compact Dimunitive
  • 35. Monarch®III &D Cartridge Designed for ACRYSOF IQ PanOptix/ Toric
  • 36.
  • 41.
  • 42.
  • 44. COMPLICATIONS  Trapped trailing haptic  Haptic optic adhesion  Misdirected leading haptic  Twisted haptic  Overriding plunger  Trauma to IOL: damage to IOL haptic/optic:
  • 45. COMPLICATIONS  Damage to IOL haptic/optic:  poor IOL injector design and packaging Nguyen DQ, Saleh TA, Pandey SK, Bates AK. Irregularities on the surface of single-piece AcrySof SA60ATintraocular lenses. J Cataract Refract Surg 2006;32(3):495–498  Inappropriate manual handling and loading, Vrabec MP, Syverud JC, Burgess CJ. Forceps-induced scratching of a foldable acrylic intraocular lens. Arch Ophthalmol1996;114(6):777  Overriding injector plungers,  Friction during IOL passage through the injector nozzle - type of viscoelastic medium used for loading and IOL injection Myers TD, Olson RJ. Comparison of the effects of viscoelastic agents on clinical properties of the unfolder lens injection system. J Cataract Refract Surg 1999;25(7):953–958
  • 47. • IOL manufacturers are keenly working on the development of better preloaded IOL delivery systems. • The focus is on making IOL size, design, and thickness more compatible with the disposable plunger and cartridge assembly. • In the near future, all IOL implantations will be performed through preloaded IOL delivery systems. • The healthy competition among manufacturers to achieve the best system will not only provide us with flawless IOL delivery but will also make these products more cost-effective
  • 48. • Foldable IOLs have helped alter the face of cataract surgery by improving healing time, limiting complications and making phacoemulsification the standard procedure over extracapsular surgery, all in the span of 3 decades • Advancements in cataract surgery have necessitated the availability of intraocular lens preloaded delivery systems that can safely, effectively and predictably deliver IOLs in the eye. • Preloaded delivery systems simplify and reduce procedural variability during surgery preparation. Clearly, cataract surgery continues to improve in all areas, with a bright future for improved vision and a happy patient.
  • 49. Vision Leadership in the Eye Care Domain Mission Vision Care Par Excellence smithsnehalsute@yahoo.com

Notes de l'éditeur

  1. A critical step in cataract surgery is the delivery of the intraocular lens (IOL) into the eye, and recent advances in how IOLs are deployed means surgeons now have the option to use both manual IOL injectors and preloaded IOL injectors.
  2. As the demand for cataract surgery grows with the aging population and increased prevalence, improved safety and efficiency in the operating room become more important. Newer preloaded IOL systems might help satisfy these ever-increasing stringent requirements.