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Modera: Paris de l’Etraz
Varis, Natalia
SIN DELANTAL
SinDelantal, order food online from delivery & takeaway
                      restaurants
Evolution of
     orders




 Number of
restaurants
Next
steps
Thanks
   !



         SinDelantal.com, june 2011
Gabriel Barón
ONCOVISION
Vision Technology to Cure Cancer



                  Gabriel Gonzalez Pavón, MD
                  Spain Startup & Investor Summit
                  Madrid, 7th of June, 2012


                                                    13
My (very) personal journey: “Don Quijote rides again”


•   From surgery to an outstanding Corporation during 21 years




•   … and from seven business units, two secretaries, Global and European Corporate Boards and a
    “corner office” to a corner garage

•   Creating a highly profitable business by making a real difference in curing cancer, patient by
    patient, with breakthrough innovation


…and my story is one of many similar at Oncovision
1a. Cancer: the enemy inside


     “FIRST CAUSE OF DEATH WORLDWIDE SINCE 2010”
     (World Health Observatory UN/WHO, December, 2009)                                                            Incidence, colon cancer, 2010


•   Cancer is a generic term encompassing 200+ types of malignant tumours, with very significant
    mortality and growing incidence
     –   165.000 new cases diagnosed per year in Spain, 80+ million of new patients per year worldwide
     –   Case in point: Mortality by breast cancer: 480.000+ worldwide, best case survival 77%, often under 50%




    “Abnormal growth of tissues or cells which expands both locally and at a distance, in other parts
    of the body, invading first regional lymph nodes (in more than 90% of tumours) and generating
    later metastasis (new satellite tumours in other locations)”


                                                             Two hundred+ enemies, no unique or “magic” solution

                                                                                           PERSONALIZED CARE CRITICAL
1b. Cancer: Still many unsolved questions, lives at risk



“25% to 30% of node
negative breast cancer                    ¿Why do I have high (>27% ) recurrence rates
                                           after “oncologically correct” surgery in advanced
patients will develop local                colon cancer?. How can my patients do better?
recurrences or distant                     S. Saha (McLaren Regional Medical Center, Flint, MI, USA at the VII World
metastases within 10 years.                   Congress of the ISNS (International Sentinel Node Society, November
                                              2011)
Studies have suggested that this
unfavorable outcome may be due in
part to undetected occult
metastases in the lymph
nodes”
A. Sahin,M. Guray, Kelly K.
                                    “Functional drainage –as seen in
Hunt, MD Anderson. Arch Patol       lymphogammagraphy- is different from the
Lab 2009                            classic anatomical drainage patterns used as
                                    reference for surgery in 10 to 30% of melanoma
                                    patients, depending on lesion localization”
                                    Uren R et al. J NuclMed2003; 44:570-582

                                                                                                                16
2. Molecular Vision : “New Eyes” to fight cancer

    •   There are two (complementary) ways of seeing inside people:
          •   Structural imaging explorations (RX, CT, MRI) are detecting with great accuracy anatomical changes vs
              “normal” body structures
          •   Functional (molecular) imaging (gammagraphy, PET, SPECT) is detecting and quantifying abnormal
              functional activity, often BEFORE having anatomical visible impact, and measuring its evolution


    •   The new ORIGINAL technology of Oncovision is making possible “seeing cancer” in real
        time, know it better, patient by patient, and act against it.




Mammography                                                                                           PET




                                                                                                      Breast cancer, 35
                                                                                                      years old female


                                                                                                                 17
3. The great business of “doing what is right”


•   Breakthrough Innovations 2006-2012
     –   From one prototype to THREE huge potential highly differentiated product lines
     –   VERY strong support from leading global reference centers… and sales in 28 countries
     –   Multiaward winning (i.e. Best Technology Company of Spain, 2012, best preclinical innovation strategy, USA, 2011, “Jaime I”
         Entrepeneurship Award 5th of June 2012 …)
     –   Powerful pipeline and additional new lines sharing core technology & strategic alliances

•   From dreams to Discipline
     –   High profile and experienced international team… also at finance, purchasing, manufacturing, market
         development, sales, regulatory affairs…
     –   VERY rigurous management of timelines, budgets, commitments, quality
     –   REAL synergy at work: R&D alliance I3M, venture capital BULLNET, AXIS-ICO, partners & allies

•   Daring and Doing
     –   Aiming to the top KOL and cancer centers, benchmarks, ONLY perfect is good enough
     –   Proactiveness, proactiveness, proactiveness… AND customer focus / SERVICE network



                                                   ONCOVISION GAINS NET POSITIVE RESULTS IN 2012
4. Innovation brings global profitable growth


•   Equipment for cancer care: an unique opportunity
     –   Unlimited, global demand vs resistance to change, budgets and marketing power
     –   New technology does not penetrate clinical practice easily: needs to prove clinical AND economic
         advantages, regulations and reimbursement, leader and USER training
     –   Medical equipment is not (only) software: manufacturing, logistics, homologation, local service


•   From start up to global enterprise, step by step… and fast
     –   Upgrading team and capabilities
                                                                                                   Sales growth
     –   Managing development
     –   Financing production
     –   Fueling indication expansion
     –   Expanding global network
     –   Building alliances
5. How?: A crystal clear business model for explosive expansion


•   Three step “Magic Johnson approach”. Shared PRACTICAL deployment & excecution, by
    product and geography, of OCV´s core strategy, creating new / uograding markets and bringing
    profitable growth


•        EVIDENCE by pathology, country / region
    Strong clinical

• REFERENCES with top centers for support and training
• ALLIES     in      financing,          distribution/marketing,                       technical
    service, development, externalization of production, scientific societies, patient
    advocacy groups, media, insurance companies…




                                  • Programmed launching of INNOVATIONS
                             • FLEXIBLE and proactive competitive positioning
                           • Managing aggressive SUSTAINABLE global growth
                                                                                              20
6. THREE revolutionary product lines in global expansion (1/3)




•   The base of it all, and a worldwide success, redefining personalized cancer surgery

•    EXCLUSIVE FULLY INTEGRATED cancer detection EQUIPMENT gammacamera + pointers + gamma probe + CAD
    software for REAL TIME VISION in the OR of tumors and lymph nodes.
            Revolution en RADIO_GUIDED SURGERY (beginning with Sentinel node biopsy) of both superficial and
               deep draining tumors.
            GUARANTEES and documents completness of cancer surgery, patient by patient
            SEVEN         additional    high    volume      indications: critical   care,     encephallic    death
               confirmation, trasplant, treatment control in advanced chemoteraphy, cardiac reconstruction, diabetic
               foot, “ligth” gammagraphy in remote Hospitals

   105+ units installed in 28 countries, 20.000+ patients, 26 cancer types (June 2012)

   VERY STRONG clinical and economic evidence and support from top global oncology centers

      Market undergoing explosive growth (VISION + expansion from 12 a 150+ tumours…)




                                                                                                                21
DEVELOPMENT TIME TO
       OPTIMIZED
    PRODUCT: 4 YEARS


First clinical prototype camera ,
October 2004




                                                                      NEW Sentinella 2
                       Third generation Sentinella 102,
                                                                      April, 2011
                       September 2008




                                                                                         22
             INTEGRATED gamma camera + gamma probe + pointer + CAD software
Sentinella in acction: Prostate cancer surgery at   NKI-AWL Amsterdam




                                             Courtesy of Drs. R. Valdés, A Bex, S. Horemblas
                                                                                        23
                                             NKI-AWL, Amsterdam, The Netherlands
6. THREE revolutionary product lines in global expansion (2/3)




•      The most complex product line, multimodal equipment for advanced in-vivo research
    in rats and mice in oncology, neurology, cardiology and new drug / treatment development

•      EXCLUSIVE FULLY INTEGRATED PET+SPECT+CT with unqualled performance AND ease of use
              Changing basis of competition in preclinical imaging (lower costs, faster explorations, easy
                maintenance and MODULAR upgrade options)
              OCV markets direct in Spain and Portugal, ROW CARESTREAM MOLECULAR IMAGING

     19 units installed in 14 countries -15+ underway in 2012-, 30.000+ studies (June 2012)

     VERY competitive vs previous best in class SIEMENS, only two other (minor) competitors


         Market undergoing major growth (core labs, pharma companies, upgrade to multimodal…)




                                                                                                     24
ALBIRA MULTIMODAL (PET+SPECT+CT), September 2008


Prototype IFIC, December 2005




                Albira PET, November 2007




                                                                DEVELOPMENT TIME TO
                                                               OPTIMIZED PRODUCT: 2 1/2
                                                                                     25
                                                                        YEARS
Same soul, upgraded capabilities, new face, global success:
                      Albira II, March 2010




                                             Best Preclinical Innovation
                                             strategy award 2011, USA



                                                                   26
Skeleton & abdominal organs, mouse


FOUR simultaneous mice studies!
                                                                                                             Mouse heart




                                                                             FIVE vision modalities Albira + Carestream
                 Fusion PET (3D) & 3D MRI. Brain ischemia, mouse

                                                                                                                    27
6. THREE revolutionary product lines in global expansion (3/3)




•   A clinical evolution of Albira PET, the biggest potential of all (medium term 4.400 centers, long 40.000+) and a true
    breakthrough im breast cancer diagnosis and treatment assessment

•   GLOBAL EXCLUSIVE TRUE 3D, prone position NO compression dedicated PET mammography, with unprecedented
    diagnostic reliability, very fast explorations, minimal radiation dose (below X ray mammography, of which it is complementary)
    and remarkable ease of use

•   Detects and measures agressiveness of possible BC tumors even of minimal size, in young women, dense or fibroquistic
    breasts, differentiating benign from malign lesions
              Indicated in very early diagniosis of breast cancer in women from groups of risk, confirmation of suspicious
                 lesions identified in screening, avoiding unnecessary biopsies, local follow up post surgery and VERY fast (<3
                 weeks vs 10-12) and effective measurement of results of chemotherapy, hormonoteraphy or radiotheraphy

   Launched November 2011, 4 units installed (6 underway short term) in 4 countries

   VERY STRONG clinical support from top global oncology centers




                                                                                                                             28
Whole body PET




                                                   Mammi dedicated PET


                                                   Vastly improved accuracy
                                                      and quantification

First MAMMI installed at NKI Amsterdam, May 2011
EXCLUSIVE TRUE 3 D
9. The best is yet to come: Developments under way


1. (Funded) Innovations & clinical improvements in EXISTING product lines

      • Further capabilities and ease of use: expansion modules and upgrades
            (multimodality, 3D, improved resolution, sensitivity, speed, software, ergonomics…).
      • Product segmentation by clinical indication:
            (Dedicated equipment configurations i.e cardiac, critical care, portable gamma units, software variants…)
      • Improved auxiliary elements to further optimize tumour detection AND treatment

2. (Funded) Major technology upgrades and cost reductions

      • Detectors, electronics, software, engineering i.e targeting 40% cost reduction in 2 years
      • Vast performance improvement based in exclusive continuous crystal – based modules

3. (Funded) NEW product lines, sharing core technology and expertise

      • Neuro-PET for cerebrovascular (i.e. stroke), cancer and neurodegenerative diseases
      • PET-MRI & other clinical and other multimodality options
      • “Metastases search “units, including CAD and other surgical decision support tools
      • Surgical / interventional navigation equipment




                                                                                                                        31
10. In conclussion, how does Oncovision measure up?


– THREE active, breakthrough product lines based on shared core technology
     • PROVEN INNOVATIVE, ORIGINAL, PATENTED TECHNOLOGY
     • Very significant and expanding market opportunities and new lines (i.e Neurology)
     • Very close alliances with key innovators

–   PRESENCE WITH SENTINELLA IN 28 COUNTRIES, ALBIRA in 15, MAMMI in 4
     • Outstanding published evidence and global leader personal support
     • Strong evidence and reference center network
     • CARESTREAM ALLIANCE and other strategic negotiations underway

– PROVEN MANUFACTURING, COMMERCIAL and REGULATORY CAPABILITIES

– OUTSTANDING DIRECT and allied INNOVATION and DEVELOPMENT teams


– A TRUSTWORTHY PARTNER FOR TODAY AND TOMORROW

– A SOUND, HIGHLY PROFITABLE INVESTMENT


                                                                                           32
Vision Technology to Cure Cancer




                       New facility at CIPF Valencia, Spain   33
Pilar Manchón
INDISYS
BUSINESS PLAN: INTERNATIONALIZATION




INTELLIGENT NATURAL LANGUAGE SOLUTIONS


                                  PILAR MANCHÓN
Challenge
    • Large organizations seek:

       – Increasing revenue

       – Minimizing costs

       – 24x7 customized & excellent support

       – Excellent UX

       – Information exploitation & management
Global Solution
“One coherent, excellent & personalized User Experience across all channels”.


                             Mobile Virtual Assistants

                                             Social Media

                      Online Virtual                     Email
                       Assistants                        Response
                                                         Management




                        Virtual                      E-Learning
                        Telephone
                        Operators                          Live Chat
Human Capital
Executive Team                   Board of Advisors


Pilar Manchón: PhD               Kenneth Morse
Gabriel Amores: PhD              Laura Morse
Guillermo Pérez: PhD             Juan Martínez Barea




                            Investors
                 • Founders:         €80K
                 • Business Angels          €193K
                 • VC (Invercaria)             €527K
Indisys: The company
         Awards                 Team Background
•   Call To Innovation 2012
                                • Computational Linguistics
•   “Cool Vendors 2010”
•   Innovation Award 2010
                                • Artificial Intelligence
•   Innovation Award 2009       • Cognitive Science
•   Best User Experience 2009
                                • Machine Learning

                                • Computer Science

                                • Telecommunications


                                       Headcount
                                             20
Technology: locuaz


Domain & language independent brain that engages the
  user in intelligent and flexible human-like dialogue.




                                                      Maya
International Success Stories
Market Size & Competition
•   $ 1 B for Virtual Assistants (Gartner 2012)
                                                                +$ 3.5 B
•   $ 1,5 B for Virtual Operators (Frost & Sullivan 2011)
•   $ 1 B? for SME VA untapped market (Indisys 2012)
•   $ xx B? for B2C Mobile Applications

                                   • Small number of competitors
                                   • None with equal or superior technology


    Competitive Advantage
     •   Experienced & committed team
     •   Superior Technology
     •   Great references
     •   Strategic Partners
     •   Position, visibility, brand image
What we seek…                           What it is for…
B-round:                            •   Finance existing opportunities

                                    •   Creating more opportunities

                                    •   Increasing Sales & Exec Team (US)

                                    •   Patenting the technology
    $ 2-3 M                         •   Financing additional revenue channel

                                    •   Growing fast to lead the market



              Our Objective
              “Total global domination of our market niche”
                                                 Kenneth P. Morse
We look forward
to working with
you.

 Thank you!

  Pilar Manchón
  Intelligent Dialogue Systems
  p.manchon@indisys.es
  +34 625 377 440
  +1 650 804 0867
Xavier Samsó
MINIMA
The Autonomous Coffee Maker

                                  New concept of outdoors:

                                 Espresso anywhere-anytime

                                Portable, autonomous, free of
                                       energy sources.


The System: Fluid compression

                                        IP Protection

                                     Freedom to Operate

                                Applications for coffee makers
                                      and other sectors
Professional Coffee makers
… 1950        1961           1990                      2012
                                                       …




The New Generation
                             Flat Professional coffee makers
                              Direct exploitation to coffee
                                        roasters
                                    Home Coffee Makers
                                    Technology transfer
                                     Strategic alliances
Competitive advantages

 Perfect Coffee           Compatibility

                              For all
 Top Espresso                Espresso
   Quality                   Systems



Low Production            Energy Savings
    Costs
 Simplicity of              80 % less
 components                 electricity




No Calcification              Silent

Technic Service           No noises while
   friendly                 operating
Our Company
                                    8 experienced owners
                                    Average of 46 years old

                                     5 Employees at I+D

                                        5 Tech Centers:
                                 ASCAMM, CIM, CRIC, IRTA,LEITAT

Investments

Share Capital:       215.000 €       New Investments 2012-13
Private Investors:   250.000 €   Shares & Private: 500.000 €
CDTI:                295.000 €   ENISA:            150.000 €
ENISA:               100.000 €   Cdti:             250.000 €

Total investments: 860.000 €     Total 2012/13:      900.000 €
Road Map to success

                              Research, technology feasibility,
       2009 – April 2012      IP protection
                              Product range
                              Stategic Alliances
                End of 2012
                              Technology transfer agreements
                              Capital Increases

   April 2013                 Launch
                              Autonomous Coffee Makers
   May 2012 – June 2013       Professional Coffee Markers Project


                              Launch
       October 2013           Professional Coffee Makers
To innovate we need to imagine
Pablo Elosúa
YUNAIT
pablo elosúa
            founder & ceo




one stop place
for daily deals
all deals in
        one
web / email


 free your inbox!
user power



we let the user decide
we know what
    our users
           love


 user intelligence
dealhunter



 deals on the
           go
500K
  users
business model

qualified traffic
                    partner
                     sites
    revenue
market


€5bn
  global
market


€200m
year (spain)
our performance


€1m
monthly sales
through yunait
our performance


1,500
coupons sold
    everyday
spain
uk
italy
brazil
portugal
dream team
thanks!
Thomas Petit
TUS JUEGOS
What we do

 Digital videogames Ecommerce
  localized for Latin markets



 Digital downloads

 Games for PC & Mac

 Full localization

 1000+ titles

 All discounted from retail price
Founders & Staff


                                                                                   Inversores




Jaume Ferre Carlos Blanco            Sergio Rincón      Ramon Farell
CEO         Business Dev.            Key Partnerships   Sales Strategy




      Team
       10 pax
                            Eloi Poch         Thomas Petit       Rúben Jimenez
                            IT & Operations   Marketing          Product Manager
Our Market

 Volume
                  # Players   Games $    PC/Mac    % Digitalized



           SP       16M       1,6 MM€    480 M€       <40%
           BR       35M        $2 MM     $600 M        50%
           IT       14M       1,7 MM€    510M €       <40%
                                                                   Source
           FR       24M       3,2 MM€    800M €        45%
           US      145M       21,6 MM€   4300M €      >60%


  Trend: Digitalization
Current Status

Funding                          Operations/Sales
200,000+€ from founders          2011 Shop opens
400,000+€ Seed Capital           2012 Traction > growth



News




                   http://TusJuegos.com/Solidario/
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Spain Startup Pitches 2

  • 3. SinDelantal, order food online from delivery & takeaway restaurants
  • 4.
  • 5.
  • 6.
  • 7.
  • 8. Evolution of orders Number of restaurants
  • 10. Thanks ! SinDelantal.com, june 2011
  • 11.
  • 13. Vision Technology to Cure Cancer Gabriel Gonzalez Pavón, MD Spain Startup & Investor Summit Madrid, 7th of June, 2012 13
  • 14. My (very) personal journey: “Don Quijote rides again” • From surgery to an outstanding Corporation during 21 years • … and from seven business units, two secretaries, Global and European Corporate Boards and a “corner office” to a corner garage • Creating a highly profitable business by making a real difference in curing cancer, patient by patient, with breakthrough innovation …and my story is one of many similar at Oncovision
  • 15. 1a. Cancer: the enemy inside “FIRST CAUSE OF DEATH WORLDWIDE SINCE 2010” (World Health Observatory UN/WHO, December, 2009) Incidence, colon cancer, 2010 • Cancer is a generic term encompassing 200+ types of malignant tumours, with very significant mortality and growing incidence – 165.000 new cases diagnosed per year in Spain, 80+ million of new patients per year worldwide – Case in point: Mortality by breast cancer: 480.000+ worldwide, best case survival 77%, often under 50% “Abnormal growth of tissues or cells which expands both locally and at a distance, in other parts of the body, invading first regional lymph nodes (in more than 90% of tumours) and generating later metastasis (new satellite tumours in other locations)” Two hundred+ enemies, no unique or “magic” solution PERSONALIZED CARE CRITICAL
  • 16. 1b. Cancer: Still many unsolved questions, lives at risk “25% to 30% of node negative breast cancer ¿Why do I have high (>27% ) recurrence rates after “oncologically correct” surgery in advanced patients will develop local colon cancer?. How can my patients do better? recurrences or distant S. Saha (McLaren Regional Medical Center, Flint, MI, USA at the VII World metastases within 10 years. Congress of the ISNS (International Sentinel Node Society, November 2011) Studies have suggested that this unfavorable outcome may be due in part to undetected occult metastases in the lymph nodes” A. Sahin,M. Guray, Kelly K. “Functional drainage –as seen in Hunt, MD Anderson. Arch Patol lymphogammagraphy- is different from the Lab 2009 classic anatomical drainage patterns used as reference for surgery in 10 to 30% of melanoma patients, depending on lesion localization” Uren R et al. J NuclMed2003; 44:570-582 16
  • 17. 2. Molecular Vision : “New Eyes” to fight cancer • There are two (complementary) ways of seeing inside people: • Structural imaging explorations (RX, CT, MRI) are detecting with great accuracy anatomical changes vs “normal” body structures • Functional (molecular) imaging (gammagraphy, PET, SPECT) is detecting and quantifying abnormal functional activity, often BEFORE having anatomical visible impact, and measuring its evolution • The new ORIGINAL technology of Oncovision is making possible “seeing cancer” in real time, know it better, patient by patient, and act against it. Mammography PET Breast cancer, 35 years old female 17
  • 18. 3. The great business of “doing what is right” • Breakthrough Innovations 2006-2012 – From one prototype to THREE huge potential highly differentiated product lines – VERY strong support from leading global reference centers… and sales in 28 countries – Multiaward winning (i.e. Best Technology Company of Spain, 2012, best preclinical innovation strategy, USA, 2011, “Jaime I” Entrepeneurship Award 5th of June 2012 …) – Powerful pipeline and additional new lines sharing core technology & strategic alliances • From dreams to Discipline – High profile and experienced international team… also at finance, purchasing, manufacturing, market development, sales, regulatory affairs… – VERY rigurous management of timelines, budgets, commitments, quality – REAL synergy at work: R&D alliance I3M, venture capital BULLNET, AXIS-ICO, partners & allies • Daring and Doing – Aiming to the top KOL and cancer centers, benchmarks, ONLY perfect is good enough – Proactiveness, proactiveness, proactiveness… AND customer focus / SERVICE network ONCOVISION GAINS NET POSITIVE RESULTS IN 2012
  • 19. 4. Innovation brings global profitable growth • Equipment for cancer care: an unique opportunity – Unlimited, global demand vs resistance to change, budgets and marketing power – New technology does not penetrate clinical practice easily: needs to prove clinical AND economic advantages, regulations and reimbursement, leader and USER training – Medical equipment is not (only) software: manufacturing, logistics, homologation, local service • From start up to global enterprise, step by step… and fast – Upgrading team and capabilities Sales growth – Managing development – Financing production – Fueling indication expansion – Expanding global network – Building alliances
  • 20. 5. How?: A crystal clear business model for explosive expansion • Three step “Magic Johnson approach”. Shared PRACTICAL deployment & excecution, by product and geography, of OCV´s core strategy, creating new / uograding markets and bringing profitable growth • EVIDENCE by pathology, country / region Strong clinical • REFERENCES with top centers for support and training • ALLIES in financing, distribution/marketing, technical service, development, externalization of production, scientific societies, patient advocacy groups, media, insurance companies… • Programmed launching of INNOVATIONS • FLEXIBLE and proactive competitive positioning • Managing aggressive SUSTAINABLE global growth 20
  • 21. 6. THREE revolutionary product lines in global expansion (1/3) • The base of it all, and a worldwide success, redefining personalized cancer surgery • EXCLUSIVE FULLY INTEGRATED cancer detection EQUIPMENT gammacamera + pointers + gamma probe + CAD software for REAL TIME VISION in the OR of tumors and lymph nodes.  Revolution en RADIO_GUIDED SURGERY (beginning with Sentinel node biopsy) of both superficial and deep draining tumors.  GUARANTEES and documents completness of cancer surgery, patient by patient  SEVEN additional high volume indications: critical care, encephallic death confirmation, trasplant, treatment control in advanced chemoteraphy, cardiac reconstruction, diabetic foot, “ligth” gammagraphy in remote Hospitals  105+ units installed in 28 countries, 20.000+ patients, 26 cancer types (June 2012)  VERY STRONG clinical and economic evidence and support from top global oncology centers  Market undergoing explosive growth (VISION + expansion from 12 a 150+ tumours…) 21
  • 22. DEVELOPMENT TIME TO OPTIMIZED PRODUCT: 4 YEARS First clinical prototype camera , October 2004 NEW Sentinella 2 Third generation Sentinella 102, April, 2011 September 2008 22 INTEGRATED gamma camera + gamma probe + pointer + CAD software
  • 23. Sentinella in acction: Prostate cancer surgery at NKI-AWL Amsterdam Courtesy of Drs. R. Valdés, A Bex, S. Horemblas 23 NKI-AWL, Amsterdam, The Netherlands
  • 24. 6. THREE revolutionary product lines in global expansion (2/3) • The most complex product line, multimodal equipment for advanced in-vivo research in rats and mice in oncology, neurology, cardiology and new drug / treatment development • EXCLUSIVE FULLY INTEGRATED PET+SPECT+CT with unqualled performance AND ease of use  Changing basis of competition in preclinical imaging (lower costs, faster explorations, easy maintenance and MODULAR upgrade options)  OCV markets direct in Spain and Portugal, ROW CARESTREAM MOLECULAR IMAGING  19 units installed in 14 countries -15+ underway in 2012-, 30.000+ studies (June 2012)  VERY competitive vs previous best in class SIEMENS, only two other (minor) competitors  Market undergoing major growth (core labs, pharma companies, upgrade to multimodal…) 24
  • 25. ALBIRA MULTIMODAL (PET+SPECT+CT), September 2008 Prototype IFIC, December 2005 Albira PET, November 2007 DEVELOPMENT TIME TO OPTIMIZED PRODUCT: 2 1/2 25 YEARS
  • 26. Same soul, upgraded capabilities, new face, global success: Albira II, March 2010 Best Preclinical Innovation strategy award 2011, USA 26
  • 27. Skeleton & abdominal organs, mouse FOUR simultaneous mice studies! Mouse heart FIVE vision modalities Albira + Carestream Fusion PET (3D) & 3D MRI. Brain ischemia, mouse 27
  • 28. 6. THREE revolutionary product lines in global expansion (3/3) • A clinical evolution of Albira PET, the biggest potential of all (medium term 4.400 centers, long 40.000+) and a true breakthrough im breast cancer diagnosis and treatment assessment • GLOBAL EXCLUSIVE TRUE 3D, prone position NO compression dedicated PET mammography, with unprecedented diagnostic reliability, very fast explorations, minimal radiation dose (below X ray mammography, of which it is complementary) and remarkable ease of use • Detects and measures agressiveness of possible BC tumors even of minimal size, in young women, dense or fibroquistic breasts, differentiating benign from malign lesions  Indicated in very early diagniosis of breast cancer in women from groups of risk, confirmation of suspicious lesions identified in screening, avoiding unnecessary biopsies, local follow up post surgery and VERY fast (<3 weeks vs 10-12) and effective measurement of results of chemotherapy, hormonoteraphy or radiotheraphy  Launched November 2011, 4 units installed (6 underway short term) in 4 countries  VERY STRONG clinical support from top global oncology centers 28
  • 29. Whole body PET Mammi dedicated PET Vastly improved accuracy and quantification First MAMMI installed at NKI Amsterdam, May 2011
  • 31. 9. The best is yet to come: Developments under way 1. (Funded) Innovations & clinical improvements in EXISTING product lines • Further capabilities and ease of use: expansion modules and upgrades (multimodality, 3D, improved resolution, sensitivity, speed, software, ergonomics…). • Product segmentation by clinical indication: (Dedicated equipment configurations i.e cardiac, critical care, portable gamma units, software variants…) • Improved auxiliary elements to further optimize tumour detection AND treatment 2. (Funded) Major technology upgrades and cost reductions • Detectors, electronics, software, engineering i.e targeting 40% cost reduction in 2 years • Vast performance improvement based in exclusive continuous crystal – based modules 3. (Funded) NEW product lines, sharing core technology and expertise • Neuro-PET for cerebrovascular (i.e. stroke), cancer and neurodegenerative diseases • PET-MRI & other clinical and other multimodality options • “Metastases search “units, including CAD and other surgical decision support tools • Surgical / interventional navigation equipment 31
  • 32. 10. In conclussion, how does Oncovision measure up? – THREE active, breakthrough product lines based on shared core technology • PROVEN INNOVATIVE, ORIGINAL, PATENTED TECHNOLOGY • Very significant and expanding market opportunities and new lines (i.e Neurology) • Very close alliances with key innovators – PRESENCE WITH SENTINELLA IN 28 COUNTRIES, ALBIRA in 15, MAMMI in 4 • Outstanding published evidence and global leader personal support • Strong evidence and reference center network • CARESTREAM ALLIANCE and other strategic negotiations underway – PROVEN MANUFACTURING, COMMERCIAL and REGULATORY CAPABILITIES – OUTSTANDING DIRECT and allied INNOVATION and DEVELOPMENT teams – A TRUSTWORTHY PARTNER FOR TODAY AND TOMORROW – A SOUND, HIGHLY PROFITABLE INVESTMENT 32
  • 33. Vision Technology to Cure Cancer New facility at CIPF Valencia, Spain 33
  • 34.
  • 36. BUSINESS PLAN: INTERNATIONALIZATION INTELLIGENT NATURAL LANGUAGE SOLUTIONS PILAR MANCHÓN
  • 37. Challenge • Large organizations seek: – Increasing revenue – Minimizing costs – 24x7 customized & excellent support – Excellent UX – Information exploitation & management
  • 38. Global Solution “One coherent, excellent & personalized User Experience across all channels”. Mobile Virtual Assistants Social Media Online Virtual Email Assistants Response Management Virtual E-Learning Telephone Operators Live Chat
  • 39. Human Capital Executive Team Board of Advisors Pilar Manchón: PhD Kenneth Morse Gabriel Amores: PhD Laura Morse Guillermo Pérez: PhD Juan Martínez Barea Investors • Founders: €80K • Business Angels €193K • VC (Invercaria) €527K
  • 40. Indisys: The company Awards Team Background • Call To Innovation 2012 • Computational Linguistics • “Cool Vendors 2010” • Innovation Award 2010 • Artificial Intelligence • Innovation Award 2009 • Cognitive Science • Best User Experience 2009 • Machine Learning • Computer Science • Telecommunications Headcount 20
  • 41. Technology: locuaz Domain & language independent brain that engages the user in intelligent and flexible human-like dialogue. Maya
  • 43. Market Size & Competition • $ 1 B for Virtual Assistants (Gartner 2012) +$ 3.5 B • $ 1,5 B for Virtual Operators (Frost & Sullivan 2011) • $ 1 B? for SME VA untapped market (Indisys 2012) • $ xx B? for B2C Mobile Applications • Small number of competitors • None with equal or superior technology Competitive Advantage • Experienced & committed team • Superior Technology • Great references • Strategic Partners • Position, visibility, brand image
  • 44. What we seek… What it is for… B-round: • Finance existing opportunities • Creating more opportunities • Increasing Sales & Exec Team (US) • Patenting the technology $ 2-3 M • Financing additional revenue channel • Growing fast to lead the market Our Objective “Total global domination of our market niche” Kenneth P. Morse
  • 45. We look forward to working with you. Thank you! Pilar Manchón Intelligent Dialogue Systems p.manchon@indisys.es +34 625 377 440 +1 650 804 0867
  • 46.
  • 48.
  • 49. The Autonomous Coffee Maker New concept of outdoors: Espresso anywhere-anytime Portable, autonomous, free of energy sources. The System: Fluid compression IP Protection Freedom to Operate Applications for coffee makers and other sectors
  • 50. Professional Coffee makers … 1950 1961 1990 2012 … The New Generation Flat Professional coffee makers Direct exploitation to coffee roasters Home Coffee Makers Technology transfer Strategic alliances
  • 51. Competitive advantages Perfect Coffee Compatibility For all Top Espresso Espresso Quality Systems Low Production Energy Savings Costs Simplicity of 80 % less components electricity No Calcification Silent Technic Service No noises while friendly operating
  • 52. Our Company 8 experienced owners Average of 46 years old 5 Employees at I+D 5 Tech Centers: ASCAMM, CIM, CRIC, IRTA,LEITAT Investments Share Capital: 215.000 € New Investments 2012-13 Private Investors: 250.000 € Shares & Private: 500.000 € CDTI: 295.000 € ENISA: 150.000 € ENISA: 100.000 € Cdti: 250.000 € Total investments: 860.000 € Total 2012/13: 900.000 €
  • 53. Road Map to success Research, technology feasibility, 2009 – April 2012 IP protection Product range Stategic Alliances End of 2012 Technology transfer agreements Capital Increases April 2013 Launch Autonomous Coffee Makers May 2012 – June 2013 Professional Coffee Markers Project Launch October 2013 Professional Coffee Makers
  • 54. To innovate we need to imagine
  • 55.
  • 56.
  • 58. pablo elosúa founder & ceo one stop place for daily deals
  • 59. all deals in one web / email free your inbox!
  • 60. user power we let the user decide
  • 61. we know what our users love user intelligence
  • 64. business model qualified traffic partner sites revenue
  • 72.
  • 74.
  • 75. What we do Digital videogames Ecommerce localized for Latin markets Digital downloads Games for PC & Mac Full localization 1000+ titles All discounted from retail price
  • 76. Founders & Staff Inversores Jaume Ferre Carlos Blanco Sergio Rincón Ramon Farell CEO Business Dev. Key Partnerships Sales Strategy Team 10 pax Eloi Poch Thomas Petit Rúben Jimenez IT & Operations Marketing Product Manager
  • 77. Our Market Volume # Players Games $ PC/Mac % Digitalized SP 16M 1,6 MM€ 480 M€ <40% BR 35M $2 MM $600 M 50% IT 14M 1,7 MM€ 510M € <40% Source FR 24M 3,2 MM€ 800M € 45% US 145M 21,6 MM€ 4300M € >60% Trend: Digitalization
  • 78. Current Status Funding Operations/Sales 200,000+€ from founders 2011 Shop opens 400,000+€ Seed Capital 2012 Traction > growth News http://TusJuegos.com/Solidario/