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Laryngeal disordersLaryngeal disorders
DR MAHIPALDR MAHIPAL
Laryngeal disordersLaryngeal disorders
BY/DR KBY/DR K
SUBHASH.,DRSUBHASH.,DR
SRIDHAR,DRSRIDHAR,DR
SREEKANTH AND ALLSREEKANTH AND ALL
ENT SURGEONS OFENT SURGEONS OF
Pretest T or FPretest T or F
1. Reurrent laryngeal nerve1. Reurrent laryngeal nerve pure motor fiberpure motor fiber
larynxlarynx
3. Acute laryngitis3. Acute laryngitis
4.4. epiglottitis laryngospasmepiglottitis laryngospasm
5. Thumb5. Thumb’’s signs sign croupcroup
6. Vocal nodule6. Vocal nodule unilateral massunilateral mass
7. Vocal granuloma7. Vocal granuloma intubationintubation
8. Laryngeal trauma8. Laryngeal trauma intubationintubation
9. Most common symptom9. Most common symptom ของของ true vocal carcinomatrue vocal carcinoma
neck node enlargementneck node enlargement
Laryngeal disordersLaryngeal disorders
ผศผศ..นพนพ..ยงยุทธ วศินวงศ์ยงยุทธ วศินวงศ์
ภาควิชาจักษุ โสต นาสิกภาควิชาจักษุ โสต นาสิก
ลาริงซ์วิทยาลาริงซ์วิทยา
คณะแพทยศาสตร์คณะแพทยศาสตร์
Laryngeal disordersLaryngeal disorders
ObjectivesObjectives
1.1. AnatomyAnatomy
2.2. PhysiologyPhysiology
3.3. Common disordersCommon disorders
4.4. TreatmentTreatment
1. Anatomy1. Anatomy
FrameworkFramework
Muscles – intrinsicMuscles – intrinsic
- extrinsic- extrinsic
InnervationInnervation
VesselsVessels
FrameworkFramework
MusclesMuscles
IntrinsicIntrinsic – adductors ;– adductors ; thyroarytenoid (truethyroarytenoid (true
vocal cord:TVC),vocal cord:TVC),
cricoarytenoid,cricoarytenoid, interarytenoidinterarytenoid
- abductor ;- abductor ; post cricoarytenoidpost cricoarytenoid
ExtrinsicExtrinsic -- cricothyroidcricothyroid
InnervationInnervation
Inferior RLNInferior RLN
motor - all muscles except..motor - all muscles except..
sensory- below TVCsensory- below TVC
Superior RLNSuperior RLN
motor – cricothyroid musclemotor – cricothyroid muscle
sensory – above TVCsensory – above TVC
Blood supplyBlood supply
ArterialArterial
sup. laryngeal arterysup. laryngeal artery
inf. Laryngeal arteryinf. Laryngeal artery
VenousVenous
sup. & inf. Thyroid veinssup. & inf. Thyroid veins
PhysiologyPhysiology
1.1. Airway protectionAirway protection
2.2. SwallowingSwallowing
3.3. Voice productionVoice production
4.4. Air passageAir passage
ProtectionProtection
inspirationinspiration
phonationphonation
1. Inflammation - Acute & chronic laryngitis, croup,
epiglottitis, ulcer,
2. Tumor - benign, nodule, polyp, granuloma
- malignancy
3. Trauma - penetrating injury
- blunt injury
- iatrogenic
4. Congenital - cord paralysis, Laryngeal web,
subglottic stenosis
5. Miscellaneous - laryngopharyngeal reflux (LPR)
disease
Laryngeal disordersLaryngeal disorders
Common laryngeal disordersCommon laryngeal disorders
1. Acute laryngitis1. Acute laryngitis
2. Croup2. Croup
3. Epiglottitis3. Epiglottitis
4. Vocal nodule4. Vocal nodule
5. Vocal polyp5. Vocal polyp
6. Vocal granuloma6. Vocal granuloma
7. Laryngeal carcinoma7. Laryngeal carcinoma
8. Laryngeal trauma8. Laryngeal trauma
9. Laryngopharyngeal reflux (LPR)9. Laryngopharyngeal reflux (LPR)
Acute laryngitisAcute laryngitis
Pathogen - adenovirus, influenzaPathogen - adenovirus, influenza
Morexella catarrharisMorexella catarrharis
Hemophilus influenzaHemophilus influenza
Streptococcus pneumoniaeStreptococcus pneumoniae
Symptoms - hoarseness
cough, +/- fever, malaise
Sign - TVC swelling
Acute laryngitisAcute laryngitis
TreatmentTreatment - voice rest- voice rest
- mucolytic, anticold- mucolytic, anticold
+/- antibiotic+/- antibiotic
Symptoms > 2 week,
recurrent
DDx - chronic laryngitis
CroupCroup (acute laryngotracheobronchitis)(acute laryngotracheobronchitis)
- Severe respiratory infection- Severe respiratory infection
-- 6 months-2 yrs.
Pathogen - parainfluenza*influenza, adenovirus
- follow by bacterial esp. H. influenza
Symptoms - early URI symptoms
- 2-3 days
- barking cough, stridor
- exhausted, lying down
CroupCroup (acute laryngotracheobronchitis)(acute laryngotracheobronchitis)
Diagnosis - symptoms & signs
- flexible scope
- x-ray
norrowing of subglottis
“Pencil’s sign”
Pencil’s
sign
NormalNormal
CroupCroup (acute laryngotracheobronchitis)(acute laryngotracheobronchitis)
Treatment - early detection
- observe, admit
- humidification, hydration, O2
- antibiotic (penicillin)
severe - steroid
-- intubation
EpiglottitisEpiglottitis
- infection of supraglottis >> epiglottis- infection of supraglottis >> epiglottis
-- 2-10 yr., adult
Pathogen - H. influenza type B
Symptoms - early URI symptoms
- children > change very fast 6-12 hr.
- high fever, pain in throat
- นั่ง โน้มตัวมาข้างหน้า*
EpiglottitisEpiglottitis
Signs- epiglottis > swelling, inflam
- ** laryngospasm เมื่อกดลิ้น
- fiberoptic
X-ray - “Thumb’s sign”
EpiglottitisEpiglottitis
Treatment - admit, closed monitoring
- broad spectrum penicillin
- hydration, humidification
- +/- steriod
- prepare for intubation
Vocal cord noduleVocal cord nodule
- vocal abuse, over-used
- children, adult
- fibrous formation
Symptoms - hoarseness
Sign - nodule TVC> bilateral
> anterior 1/3
NoduleNodule
Treatment - voice rest
- speech therapy
- failed, recurrent > surgery
Vocal polypVocal polyp
- vocal abuse- vocal abuse
-- Reinke edema > capsule surrounding (polyp)
Symptoms - hoarseness > 2 wk
Sign - ant 1/3 TVC, unilateral
Treatment - surgery
- follow by speech therapy
ReinkeReinke’’s edemas edema
Vocal polypVocal polyp
Both polyp, noduleBoth polyp, nodule
Vocal granulomaVocal granuloma
inflammation > ulcer > granulomainflammation > ulcer > granuloma
etiology - intubation
- gastroesophageal reflux
- partial laryngectomy
Symptoms - hoarseness 2-3 wk after extubation
Vocal granulomaVocal granuloma
Sign - arytenoid, unilateral
Treatment - surgery
- follow by speech therapy
- Rx acid reflux
CarcinomaCarcinoma
Chronic irritationChronic irritation - smoking, alcohol,
pollution, acid reflux
Pathology - epithelial hyperplasia >
dysplasia >
carcinoma insitu >
carcinoma
CarcinomaCarcinoma
Symptoms > 2-3 weeks
- glottis > hoarseness
- supraglottis > dysphagia
- subglottis > airway problems
others - referred otalgia, chronic cough,
hemoptysis, lymphadenopathy,
wt. loss
CarcinomaCarcinoma
DiagnosisDiagnosis - biopsy ; indirect or direct- biopsy ; indirect or direct
laryngoscopylaryngoscopy
- extension ; CT, MRI- extension ; CT, MRI
- metastasis ; CXR, LFT- metastasis ; CXR, LFT
TreatmentTreatment - depends on staging TNM- depends on staging TNM
- early > surgery or RT alone- early > surgery or RT alone
- stage 3, 4 > combined- stage 3, 4 > combined
surgery, RT, ChemoRxsurgery, RT, ChemoRx
Laryngeal traumaLaryngeal trauma
Most common -Car accidentMost common -Car accident
OthersOthers - athlete, penetrating, gun-short- athlete, penetrating, gun-short
woundwound
S&SS&S >> location, severity>> location, severity
- stridor, bleeding, emphysema,- stridor, bleeding, emphysema,
hemoptysis, dysphagia, crepitationhemoptysis, dysphagia, crepitation
- severe case > coma- severe case > coma
Laryngeal traumaLaryngeal trauma
ชนิด การรักษา
Minor
- มีhematoma,emphysema, - explore ,แผล removetureignbody
tearofcartilage - วางdrain
- reconstructionofframework
+ intubation
Major
- multiplecartilagefracture - needintubationortracheostomy
- laryngotrachealsubluxation - exploration&reconstruction
+intraluminalstent
Laryngopharyngeal reflux (LPR)Laryngopharyngeal reflux (LPR)
Laryngopharyngeal reflux (LPR)Laryngopharyngeal reflux (LPR)
Stomach acid > reflux to esophagus + othersStomach acid > reflux to esophagus + others
= gastroesophageal reflux (GER)= gastroesophageal reflux (GER)
reflux up to larynx = LPRreflux up to larynx = LPR
EtiologyEtiology - relax sphincter, acid production- relax sphincter, acid production
food ;food ; chocolate, spicy, cola, alcohol,chocolate, spicy, cola, alcohol,
drugs ;drugs ; theophylintheophylin
llife-styleife-style ;; eat late at nighteat late at night
Laryngopharyngeal reflux (LPR)Laryngopharyngeal reflux (LPR)
SymptomsSymptoms - feel lump in the throat,- feel lump in the throat,
chronic cough,chronic cough,
regurgitation, heartburnregurgitation, heartburn
SignsSigns -- arytenoid edema, TVC swelingarytenoid edema, TVC sweling
granuloma, ulcergranuloma, ulcer
>>> carcinoma>>> carcinoma
Laryngopharyngeal reflux (LPR)Laryngopharyngeal reflux (LPR)
TreatmentTreatment - Lifestyle modification- Lifestyle modification
diet, stress, avoid eatingdiet, stress, avoid eating
before bedtimebefore bedtime
- medication- medication
protonpump inhibitor,protonpump inhibitor,
H2 antagonist, antacidH2 antagonist, antacid
+ prokinetic+ prokinetic
- surgery- surgery

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Laryngealdisorders

  • 2. Laryngeal disordersLaryngeal disorders BY/DR KBY/DR K SUBHASH.,DRSUBHASH.,DR SRIDHAR,DRSRIDHAR,DR SREEKANTH AND ALLSREEKANTH AND ALL ENT SURGEONS OFENT SURGEONS OF
  • 3.
  • 4. Pretest T or FPretest T or F 1. Reurrent laryngeal nerve1. Reurrent laryngeal nerve pure motor fiberpure motor fiber larynxlarynx 3. Acute laryngitis3. Acute laryngitis 4.4. epiglottitis laryngospasmepiglottitis laryngospasm 5. Thumb5. Thumb’’s signs sign croupcroup 6. Vocal nodule6. Vocal nodule unilateral massunilateral mass 7. Vocal granuloma7. Vocal granuloma intubationintubation 8. Laryngeal trauma8. Laryngeal trauma intubationintubation 9. Most common symptom9. Most common symptom ของของ true vocal carcinomatrue vocal carcinoma neck node enlargementneck node enlargement
  • 5. Laryngeal disordersLaryngeal disorders ผศผศ..นพนพ..ยงยุทธ วศินวงศ์ยงยุทธ วศินวงศ์ ภาควิชาจักษุ โสต นาสิกภาควิชาจักษุ โสต นาสิก ลาริงซ์วิทยาลาริงซ์วิทยา คณะแพทยศาสตร์คณะแพทยศาสตร์
  • 6. Laryngeal disordersLaryngeal disorders ObjectivesObjectives 1.1. AnatomyAnatomy 2.2. PhysiologyPhysiology 3.3. Common disordersCommon disorders 4.4. TreatmentTreatment
  • 7. 1. Anatomy1. Anatomy FrameworkFramework Muscles – intrinsicMuscles – intrinsic - extrinsic- extrinsic InnervationInnervation VesselsVessels
  • 9.
  • 10.
  • 11. MusclesMuscles IntrinsicIntrinsic – adductors ;– adductors ; thyroarytenoid (truethyroarytenoid (true vocal cord:TVC),vocal cord:TVC), cricoarytenoid,cricoarytenoid, interarytenoidinterarytenoid - abductor ;- abductor ; post cricoarytenoidpost cricoarytenoid ExtrinsicExtrinsic -- cricothyroidcricothyroid
  • 12.
  • 13.
  • 14. InnervationInnervation Inferior RLNInferior RLN motor - all muscles except..motor - all muscles except.. sensory- below TVCsensory- below TVC Superior RLNSuperior RLN motor – cricothyroid musclemotor – cricothyroid muscle sensory – above TVCsensory – above TVC
  • 15. Blood supplyBlood supply ArterialArterial sup. laryngeal arterysup. laryngeal artery inf. Laryngeal arteryinf. Laryngeal artery VenousVenous sup. & inf. Thyroid veinssup. & inf. Thyroid veins
  • 16. PhysiologyPhysiology 1.1. Airway protectionAirway protection 2.2. SwallowingSwallowing 3.3. Voice productionVoice production 4.4. Air passageAir passage
  • 18. 1. Inflammation - Acute & chronic laryngitis, croup, epiglottitis, ulcer, 2. Tumor - benign, nodule, polyp, granuloma - malignancy 3. Trauma - penetrating injury - blunt injury - iatrogenic 4. Congenital - cord paralysis, Laryngeal web, subglottic stenosis 5. Miscellaneous - laryngopharyngeal reflux (LPR) disease Laryngeal disordersLaryngeal disorders
  • 19. Common laryngeal disordersCommon laryngeal disorders 1. Acute laryngitis1. Acute laryngitis 2. Croup2. Croup 3. Epiglottitis3. Epiglottitis 4. Vocal nodule4. Vocal nodule 5. Vocal polyp5. Vocal polyp 6. Vocal granuloma6. Vocal granuloma 7. Laryngeal carcinoma7. Laryngeal carcinoma 8. Laryngeal trauma8. Laryngeal trauma 9. Laryngopharyngeal reflux (LPR)9. Laryngopharyngeal reflux (LPR)
  • 20. Acute laryngitisAcute laryngitis Pathogen - adenovirus, influenzaPathogen - adenovirus, influenza Morexella catarrharisMorexella catarrharis Hemophilus influenzaHemophilus influenza Streptococcus pneumoniaeStreptococcus pneumoniae Symptoms - hoarseness cough, +/- fever, malaise Sign - TVC swelling
  • 21.
  • 22. Acute laryngitisAcute laryngitis TreatmentTreatment - voice rest- voice rest - mucolytic, anticold- mucolytic, anticold +/- antibiotic+/- antibiotic Symptoms > 2 week, recurrent DDx - chronic laryngitis
  • 23. CroupCroup (acute laryngotracheobronchitis)(acute laryngotracheobronchitis) - Severe respiratory infection- Severe respiratory infection -- 6 months-2 yrs. Pathogen - parainfluenza*influenza, adenovirus - follow by bacterial esp. H. influenza Symptoms - early URI symptoms - 2-3 days - barking cough, stridor - exhausted, lying down
  • 24. CroupCroup (acute laryngotracheobronchitis)(acute laryngotracheobronchitis) Diagnosis - symptoms & signs - flexible scope - x-ray norrowing of subglottis “Pencil’s sign”
  • 26. CroupCroup (acute laryngotracheobronchitis)(acute laryngotracheobronchitis) Treatment - early detection - observe, admit - humidification, hydration, O2 - antibiotic (penicillin) severe - steroid -- intubation
  • 27. EpiglottitisEpiglottitis - infection of supraglottis >> epiglottis- infection of supraglottis >> epiglottis -- 2-10 yr., adult Pathogen - H. influenza type B Symptoms - early URI symptoms - children > change very fast 6-12 hr. - high fever, pain in throat - นั่ง โน้มตัวมาข้างหน้า*
  • 28. EpiglottitisEpiglottitis Signs- epiglottis > swelling, inflam - ** laryngospasm เมื่อกดลิ้น - fiberoptic X-ray - “Thumb’s sign”
  • 29. EpiglottitisEpiglottitis Treatment - admit, closed monitoring - broad spectrum penicillin - hydration, humidification - +/- steriod - prepare for intubation
  • 30. Vocal cord noduleVocal cord nodule - vocal abuse, over-used - children, adult - fibrous formation Symptoms - hoarseness Sign - nodule TVC> bilateral > anterior 1/3
  • 31. NoduleNodule Treatment - voice rest - speech therapy - failed, recurrent > surgery
  • 32. Vocal polypVocal polyp - vocal abuse- vocal abuse -- Reinke edema > capsule surrounding (polyp) Symptoms - hoarseness > 2 wk Sign - ant 1/3 TVC, unilateral Treatment - surgery - follow by speech therapy
  • 33. ReinkeReinke’’s edemas edema Vocal polypVocal polyp Both polyp, noduleBoth polyp, nodule
  • 34. Vocal granulomaVocal granuloma inflammation > ulcer > granulomainflammation > ulcer > granuloma etiology - intubation - gastroesophageal reflux - partial laryngectomy Symptoms - hoarseness 2-3 wk after extubation
  • 35. Vocal granulomaVocal granuloma Sign - arytenoid, unilateral Treatment - surgery - follow by speech therapy - Rx acid reflux
  • 36. CarcinomaCarcinoma Chronic irritationChronic irritation - smoking, alcohol, pollution, acid reflux Pathology - epithelial hyperplasia > dysplasia > carcinoma insitu > carcinoma
  • 37. CarcinomaCarcinoma Symptoms > 2-3 weeks - glottis > hoarseness - supraglottis > dysphagia - subglottis > airway problems others - referred otalgia, chronic cough, hemoptysis, lymphadenopathy, wt. loss
  • 38. CarcinomaCarcinoma DiagnosisDiagnosis - biopsy ; indirect or direct- biopsy ; indirect or direct laryngoscopylaryngoscopy - extension ; CT, MRI- extension ; CT, MRI - metastasis ; CXR, LFT- metastasis ; CXR, LFT TreatmentTreatment - depends on staging TNM- depends on staging TNM - early > surgery or RT alone- early > surgery or RT alone - stage 3, 4 > combined- stage 3, 4 > combined surgery, RT, ChemoRxsurgery, RT, ChemoRx
  • 39. Laryngeal traumaLaryngeal trauma Most common -Car accidentMost common -Car accident OthersOthers - athlete, penetrating, gun-short- athlete, penetrating, gun-short woundwound S&SS&S >> location, severity>> location, severity - stridor, bleeding, emphysema,- stridor, bleeding, emphysema, hemoptysis, dysphagia, crepitationhemoptysis, dysphagia, crepitation - severe case > coma- severe case > coma
  • 40. Laryngeal traumaLaryngeal trauma ชนิด การรักษา Minor - มีhematoma,emphysema, - explore ,แผล removetureignbody tearofcartilage - วางdrain - reconstructionofframework + intubation Major - multiplecartilagefracture - needintubationortracheostomy - laryngotrachealsubluxation - exploration&reconstruction +intraluminalstent
  • 42. Laryngopharyngeal reflux (LPR)Laryngopharyngeal reflux (LPR) Stomach acid > reflux to esophagus + othersStomach acid > reflux to esophagus + others = gastroesophageal reflux (GER)= gastroesophageal reflux (GER) reflux up to larynx = LPRreflux up to larynx = LPR EtiologyEtiology - relax sphincter, acid production- relax sphincter, acid production food ;food ; chocolate, spicy, cola, alcohol,chocolate, spicy, cola, alcohol, drugs ;drugs ; theophylintheophylin llife-styleife-style ;; eat late at nighteat late at night
  • 43. Laryngopharyngeal reflux (LPR)Laryngopharyngeal reflux (LPR) SymptomsSymptoms - feel lump in the throat,- feel lump in the throat, chronic cough,chronic cough, regurgitation, heartburnregurgitation, heartburn SignsSigns -- arytenoid edema, TVC swelingarytenoid edema, TVC sweling granuloma, ulcergranuloma, ulcer >>> carcinoma>>> carcinoma
  • 44. Laryngopharyngeal reflux (LPR)Laryngopharyngeal reflux (LPR) TreatmentTreatment - Lifestyle modification- Lifestyle modification diet, stress, avoid eatingdiet, stress, avoid eating before bedtimebefore bedtime - medication- medication protonpump inhibitor,protonpump inhibitor, H2 antagonist, antacidH2 antagonist, antacid + prokinetic+ prokinetic - surgery- surgery