2. At KWS BioTest, the latest methods and technologies are in the
hands of scientific experts - from world-leading expertise of our
CSO, Professor Neil Williams, to the extensive experience of our
highly trained staff. We generate high quality data and assist in
its interpretation through every step of your preclinical or clinical
research programme. Combined, our staff and services provide you
with improved decision-making.
We offer validated in vitro and in vivo models in:
• Immuno-oncology
• Autoimmune disease
• Inflammation and allergy
• Anti-microbials, anti-virals and vaccinology
Our CRO services are always being updated, as part of our
ongoing investment in the development of innovative models and
assay systems with improved translational value. So please get in
touch to discuss your individual needs.
WHAT WE DO
For more than a decade, KWS BioTest has been
working in immunology, inflammation and infection –
tailoring solutions to meet our clients’ needs.
If you have a programme in any of these areas, we
can work with you to design and carry out your
research and development to get you to where you
want to go.
• A broad range of
validated in vitro
and in vivo models
• Willingness to
provide a bespoke
and individual service
3. HOW WE WORK WITH YOU
At KWS BioTest, we will work with you to design and implement cost-
effective programmes that help you achieve your drug discovery and
development objectives.
KWS BioTest offers platforms which assist your critical decision-making
throughout the drug development process. These deliver early assessment
of Pharmacodynamic (PD)/efficacy biomarkers to confirm the compound
has had the desired effect on the target. This information, early in the
development process, can reduce your costs of taking drugs unnecessarily
through to later phases and increases the overall success of your
therapeutics programmes.
FLEXIBLE IN THE WAY WE WORK WITH YOU
We can provide you with dedicated staff (through FTE agreements)
that will help get longer-term projects finished faster and more
economically. Or, we can work on a fee for service basis. Whatever
your requirements, we will write a contract that works for you.
Discovery Services
• Fully ISO 9001 (2015) accredited preclinical services
• Primary human cell focused modeling of the immune
system
• Broad range of immunology/inflammation and
infection models, providing you with a comprehensive
picture of the effects of your compound(s)
• Developing and customising assays to meet
your requirements
Clinical Services
• Fully Good Clinical Practice (GCP) compliant
clinical services
• Validated cellular and functional clinical biomarker
assays to confirm translation of compound mechanism
of action in clinical trial
• Tailored biomarker assay development to
predict efficacy and immunotoxicology
• Providing critical data to underpin key decisions
throughout your drug development process
4. CAPABILITIES
Our team of scientists are expert in providing support for projects
spanning from early preclinical cell biology and in vivo efficacy models
through to clinical trial sample analysis.
Cell Biology
The cell biology team will be able to help you identify and validate
your targets; accelerate your hit-to-lead and lead optimisation; and
characterise the mechanism of action of your compounds.
Bioanalytical Services
A broad range of bioanalytical assay platforms can be accessed
in order to enable compound screening and identify PD effects.
Clinical Biomarkers
At KWS BioTest we have extensive experience in mapping immune
function in the clinic. We understand that, in early phase clinical trials,
biomarker efficacy data generated with only a small proportion of the
clinical budget may crucially contribute to the decision to progress.
In Vivo Studies
At KWS BioTest, we offer an extensive range of validated in vivo models
of human disease to support your preclinical drug efficacy testing.
Vaccine Development
Our wide range of models of bacterial and viral infection along with
our unique combination of expertise in microbiology and immunology
makes KWS BioTest an ideal partner to support your anti-microbial and
vaccine programmes.
FM 569721
info@kwsbiotest.com
