Ebola
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Ebola. Pathogenesis and prevention
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Ebola
- 5. "Ebola is a hoax."
- 9. 認識伊波拉病毒感染
- 10. 感染病原 儲存庫 病原如何 出來 易感宿主 病原如何 進入 傳播途徑 傳染鏈
- 11. Ebola 絲狀病毒科-負股RNA 五個亞種 具有套膜
- 12. 不同亞型的死亡率
- 15. 傳染途徑
- 16. 果蝠是當地野味之一
- 17. 血體液的曝觸
- 18. 風險之一 屍體的處理過程
- 21. 病毒進入宿主後的反應 Sullivan N et al. J. Virol. 2003;77:9733-9737
- 22. 病患死亡與否和病毒量的關係
- 24. 前提～沒有外力介入，沒有免疫能力
- 27. 伊波拉病毒感染防治
- 29. 簡明的流程 足夠的人力
- 30. 伊波拉疫情預測
- 31. 各國因應伊波拉疫情檢疫措施 出境衛教發燒篩檢機上廣播旅客申報主動辨識 臺灣√ √ √ √ √ 美國√ *(5機場) (來自疫區旅客) √ 加拿大√ *(6機場) (來自疫區旅客) √ 英國√ *(2機場、1火車站) (來自疫區旅客) √ 新加坡√ √ 韓國√ √ √ √ 日本√ √ √ √ 中國√ √ √ √ 香港√ √ √
- 35. 美國的教訓
- 36. Photo: Janet Loehrke, USA TODAY,
- 37. 目 前 的 新 版 本
- 38. 醫院的整備 標準作業程序 緊急採購方案 動線規劃設計
- 39. 伊波拉實驗性療法 • 藥物 – Hyper-immune globulin (humans, horses, goats) – Monoclonal antibodies (ZMapp) – Small interfering RNA (siRNA) – Favipiravir: Drugs that selectively inhibit viral RNA polymerase • 疫苗 – Recombinant vesicular stomatitis virus vaccine
- 41. 蘇迎士 感染症專科醫師 慈大藥毒所博士班 疾病管制署防疫醫師
Notes de l'éditeur
- 認識與防治
- By June, Ebola cases were being reported in Monrovia, the country’s capital. Doctors Without Borders described the situation as “totally out of control.” West Point, a township of 75,000 people in Monrovia, has been one of the hardest hit. Read more: http://www.businessinsider.com/john-moore-photos-of-ebola-epidemic-in-liberia-2014-8?op=1#ixzz3CrmjXRO6
- The misinformation going around Liberia is widespread. Some are accusing the government of creating Ebola to raise foreign aid money. Others believe the disease is caused by sorcery and that doctors are killing patients. Read more: http://www.businessinsider.com/john-moore-photos-of-ebola-epidemic-in-liberia-2014-8?op=1#ixzz3Crnpz7QF
- 某甲路過大片泥地，不小心踏上一破碎木的生鏽釘，弄傷腳底之餘，還染上破傷風（tetanus）． 破傷風菌（tentanus bacteria）是傳染原，泥土和生鏽釘是積聚處（reservoir），利器（生鏽釘）是向外輸出的門路（portal of exit），腳底被剌破的傷口是輸入的門路（portal of entry），而某甲就是易受感染的宿主（susceptible host）． 這便是一個完整的感染鏈，一個完整的感染過程．
- Host immune responses to Ebola virus and cell damage due to direct infection of monocytes and macrophages cause the release of cytokines associated with inflammation and fever (A). Infection of endothelial cells also induces a cytopathic effect and damage to the endothelial barrier that, together with cytokine effects, leads to the loss of vascular integrity (B). Transient expression of Ebola virus GP in human umbilical vein endothelial cells or 293T cells causes a reduction of specific integrins (primary molecules responsible for cell adhesion to the extracellular matrix) and immune molecules on the cell surface. Cytokine dysregulation and virus infection may synergize at the endothelial surface, promoting hemorrhage and vasomotor collapse.