Artificial Organ Technology and Market Analysis 2017 Report by Yole Developpement

From Technologies to Market
20172017
September 2017
ArtificialArtificial Organ
Technology & MarketTechnology & Market
Analysis 2017
Sample

2
OBJECTIVES OF THE REPORT
• Explain the challenges linked to organ transplantation and the limits of the current process.
• Introduce the technologies behind the different types of artificial organs (kidney, liver, lung, heart, pancreas…).
• Give an overview of history of artificial organs from first developments to nowadays, along with a presentation of
main players and their respective technologies.Who’s providing what, who’s working with whom?
• Provide market data and forecasts.
• Detail the limits of current technology and how it might evolve in the future. Discuss the main challenges, and
how artificial organs companies can overcome them. What do end-users expect? How will the healthcare industry
be impacted? How will the regulatory landscape evolve?
• Provide a focus on technical aspects of artificial organs : batteries, biocompatibility, sensors, pumping systems…
©2017 | www.yole.fr | Artificial organ | Sample

3
o OEMs & System Integrators:
• To evaluate benefits of artificial organs
• To identify the artificial organs players, types of
organs and specificities of the different
technologies used
• To understand behavioral evolution
o MEMS companies:
• To have a broad overview of all artificial organs
applications & markets
• To identify new markets
• To monitor and benchmark potential
competitors
• To understand behavior evolution
o R&D players:
• To understand new challenges in artificial organs
• To address the right market with the right
technology
o Equipment & Material suppliers:
• To understand the technical evolution of
artificial organs devices.
• To identify business opportunities and
prospects
o Financial & Strategic investors:
• To understand the potential for artificial
organs
• To know the latest developments within the
industry
• To get a list of artificial organs players and
their activities
• To understand which are the sweet spots and
what the end-users are pushing for

4
• Executive Summary 9
• Introduction 35
• The problems of organ transplantation
• Our definition of artificial organs
• Permanent vs. temporary implants
• Wearable vs. implantable
• Market Segmentation 49
• Technological and economic criteria
• Segmentation of the market
• Market Data and Forecasts 2016-2022 56
• Significant moves
• Fund raising and grants
• Market quantification
• Market data and forecasts
• Roadmap
• Segments Description 73
• Total artificial heart
• Ventricular assist devices
• Artificial pancreas
• Bioartificial pancreas
• Artificial lungs
• Artificial kidney
• Artificial liver
• Technical Aspects 154
• Biocompatibility
• Batteries
• Sensors
• Pumps
• Connectivity
• Software
• Embedded Software for Artificial organs 167
• Definitions and context
• Ventricular assist devices and total artificial heart
• Artificial pancreas
• Supply Chain 183
• Perspectives – Bionics, 3D Bioprinting and 192
Transhumanism
• Regulations: an Overview 215
• Market access of connected medical devices
• Conclusions 236
TABLE OF CONTENTS
• For each segment:
• Players
• Market size
• Technological requirements
• Company profiles
• Roadmaps

5
Biography & contact
ABOUT THE AUTHORS
Asma Siari
MarjorieVillien, PhD
As a Technology & Market Analyst, Dr. Marjorie Villien works in the Microfluidic & Medical Technologies (MedTech) business unit at Yole Développement, the "More
than Moore" market research and strategy consulting company. She is a daily contributor to the development of MedTech activities, with a dedicated collection of
market & technology reports as well as custom consulting projects. After spending two years at Harvard, Dr. Villien served as a research scientist at INSERM in the field
of MRI & PET imaging. She has spoken at numerous international conferences and has authored or co-authored 11 papers and one patent. Dr. Villien graduated from
Grenoble INP and holds a PhD in physics & medical imaging.
Email: villien@yole.fr
As a Technology & Market Analyst in the Medical Technologies (MedTech) business unit at Yole Développement (Yole), Asma Siari is involved in the development of
technology & market reports as well as the production of custom consulting projects. After a Master’s degree in Biotechnologies, Diagnostic Therapeutics &
Management, Asma serves as Research Assistant at the Moores Cancer Center (San Diego, CA). She is a coauthor in two scientific publications published in the
Molecular Cancer Research Journal. In addition to her mission at Yole, Asma is currently working on her Advanced Master’s degree in International Strategy &
Marketing BtoB (EM Lyon Business School, France).
Email: siari@yole.fr
YohannTschudi, PhD
As a Software & Market Analyst, Dr. Yohann Tschudi is a member of the MEMS & Sensors business unit at Yole Développement (Yole). Yohann is daily working with
Yole’s analysts to identify, understand and analyze the role of the software parts within any semiconductor products, from the machine code to the highest level of
algorithms. Market segments especially analyzed by Yohann include big data analysis algorithms, deep/machine learning, genetic algorithms, all coming from Artificial
Intelligence (IA) technologies.
After his thesis at CERN (Geneva, Switzerland) in particle physics, Yohann developed a dedicated software for fluid mechanics and thermodynamics applications.
Afterwards, he served during 2 years at the University of Miami (FL, United-States) as a research scientist in the radiation oncology department. He was involved in
cancer auto-detection and characterization projects using AI methods based on images from Magnetic Resonance Imaging (MRI). During his research career, Yohann has
authored and co-authored more than 10 relevant papers. Yohann has a PhD in High Energy Physics and a master degree in Physical Sciences from Claude Bernard
University (Lyon, France).
Email: tschudi@yole.fr

6
Abbott,Accellta,Alcon,Alliqua,Amesys,Amplifon,Animas,Aryballe Technologies,Asante,AWAK, Baxter, Becton
Dickinson, Berlin Heart, Betabionics, Bigfoot Biomedical, Bimba, Biofab, Bionic vision technologies, Bivacor, Breethe
inc., Carmat, Cellnovo, Cochlear Ltd, Debiotech, Dedienne, Defymed, Device Solutions, Dexcom, Diabeloop, Dose
Safety, Draper, Dreamed, Dualis, Edwards Lifesciences, Flex, Fresenius, GN ReSound, Google, Grey Innovation,
HeartWare, HEF R&D, IBMWatson, Imasonic, Inreda Diabetic, InSmart, Insulet Corporation, Intarcia, Invensense,
Jarvik Heart, Johnson and Johnson, Knowles, Kollmorgen, Lilly, MC3, Medtronic, Memscap, Minifab, Mode AGC,
Nanodialysi, Nano-dimension, Nemaura, Neokidney, Novartis, Novo Nordisk, Numerex, Omron, Organovo,
Paxitech, PixiumVision, Reliant Heart, Roche, Second Sigh, Senseonics, Siemens, Sintef, Sivantos, SmartProducts,
Sonion, Sonova, St Jude Medical, ST Microelectronics, Starkey, Syncardia,Tandem,Tandem Life,TDK-Epcos,Techshot,
Terumo,Thoratec,Transonic,TypeZero,ViaCyte,Vignal Artru,Vital Therapies,WAK,Widex,William Demant,
WiTricity, Xenios…
And many more !!
LIST OF COMPANIES MENTIONED IN THIS REPORT
230+ slides of market and technology analysis
Information gathered through direct discussions with technology developers, end-users and key opinion leaders

7
ORGAN TRANSPLANTATION
A problem to solve: shortage of human organ donors
Artificial organs
solve one of the
medical world’s
thorniest
problems
• The disparity between patients awaiting organ
transplantation and organ availability increases each
year.
• Average MedianWait Time to Transplant in the US:
• Kidney – 5 years
• Pancreas – 2 years
• Kidney / Pancreas – 1.5 years
• Liver – 11 months
• Heart – 4 months
• Lung – 4 months
• Many factors are considered while on the waiting list
including:
• Blood type
• Body size
• Distance from donor
• Severity of illness
• Time on list
** One donor can give more than one organ
Source: https://www.organdonor.gov/
In the USA
Executive Summary

8
ORGAN TRANSPLANTATION
Transplants and waiting list by organ type in the US
Kidney
transplantation
is by far the
most
frequently
carried out
transplantation
globally
• Kidney transplantation is generally accepted as the best treatment both for quality of life and cost
effectiveness.
• Organ transplantation is often the only treatment for end state organ failure, such as liver and heart failure.
Kidney
58%
Liver
23%
Heart
9%
lung
7%
Kidney/Pancreas
2%
Pancreas
1%
Transplants performed in 2015 by
organ in the US
Kidney
82%
Liver
11%
Heart
3%
Lung
1%
Other
3%
Organs people were waiting for as of
September 2016 in the US
30 814 122 071
Source of the data:
https://www.organdonor.gov/
Executive Summary

9
ARTIFICIAL ORGANS
Scope of our report
• We decided to focus on “vital” artificial organs
for our market analysis.
• We broadened the perspectives to the bionics
and transhumanism segments but didn’t quantify
this market specifically.
• We didn’t focus on bionic limbs (hands, feet, legs,
exoskeleton…) since the solutions for these
organs are more linked to robotics and this is
answered in another report “Sensors for
medical robotics”.
Artificial
organs
Total
Partial
Bionics /
transhumanism
Prosthetics /
Exoskeleton
Executive Summary

10
CONTENT OF THE REPORT
Introduction

11
Market analysis and segmentation

12
Market data and forecasts

13
Technical aspects

14
Focus on the embedded software

15
Company profiles & technology overview

16
Perspectives: Bionic man, 3D Bioprinting andTranshumanism

17
RELATED REPORTS

Organ transplantation is often the only treatment
for end-state organ failure, such as liver, kidney
and heart failure. Tragically, most people on the
waiting list die before they ever get an organ.
Hence the dream of developing artificial organs
made of electronic and mechanical parts has been
around for decades. The first total artificial heart
transplant was in the 1980s, yet since then few
improvements have made these devices more
efficient. Newcomers such as Carmat and Bivacor
are aiming to change the paradigm from a single
mechanical heart towards a smarter solution,
with embedded sensors and intelligence. The next
wave of development came from the diabetes
epidemic that affects every country, hitting
more than 8% of the global population today.
The artificial pancreas market will therefore
experience a huge 49% compound annual growth
rate (CAGR) over the next five years, to reach
$1.3B in 2022. The next breakthrough to happen
will come in 5-10 years, bringing artificial lungs and
kidneys. The first commercially approved devices
will be wearable systems such as the Wearable
Artificial Kidney Foundation, Inc. (WAKFI)
system. Soon after the first wearable kidney
we should be able see a leap to an implantable
device like that developed by the kidney project
at University of California, San Francisco and
Vanderbilt University. Artificial organs combine
many advantages besides availability, including
fewer compatibility issues, eliminating ethical
concerns around organ trafficking, and decreasing
cost. The artificial organ market will be worth
$1.3B in 2017 and its 20% CAGR over the next
five years will see it grow to $3.5B in 2022.
This report describes artificial organ market
dynamics, players and technological challenges.
ARTIFICIAL ORGAN TECHNOLOGY AND MARKET
ANALYSIS 2017
Market & Technology report - September 2017
FIVE OUT OF THE TEN LEADING CAUSES OF DEATH IN THE WORLD WILL
BENEFIT FROM ARTIFICIAL ORGANS
How will artificial organs revolutionize organ transplants and overcome shortages in the next
20 years?
KEY FEATURES OF THE REPORT
Get the sample of the report
on www.i-Micronews.com
• Introduction to the technological
differences between artificial
organs
• Comprehensive market analysis
for each segment, covering
total artificial hearts, ventricular
assist devices, artificial pancreas,
bioartificial pancreas, artificial
livers, artificial kidneys and artificial
lungs
• Funding, investments and
acquisitions
• Supply chain
• Market data and forecasts for
2016-2040 and market shares
in 2017
• Roadmaps: How will the industry
evolve?
• Technical aspects of artificial
organs such as sensors and
emitters, biocompatibility issues,
weight and volume, batteries and
pumps
• Specifications and requirements
for embedded software in the field
of artificial organs
• Types of algorithms used and
business models in the field of
software development
• Over 20 company profiles with
pictures and descriptions of their
technologies
• Some perspectives in the field of
bionics: bionic ears, bionic eyes,
bionic noses, 3D bioprinting and
transhumanism
Artificial organ market and roadmap - 2016-2040 forecasts
bioprinted heart
1st implantation of a left ventricular
assist device
1st implantation of a total
artificial heart
Hybrid closed loop
artificial pancreas
Implantable artificial heart
as a destination therapy
Wearable artificial
lung & artificial kidney
Implantable
artificial kidney
Implanted
2030
2040
2025
2020
Today
1982
1966
2
6
10
14
18
Others1
Artificial
pancreas
Ventricular
assist device
Total artificial
heart
First bioartificial
pancreas
First artificial lung and
artificial kidney
First artificial
liver
Forecasts includes systems + consumables
1
Others include artificial liver, artificial kidney,
artificial lung and bioartificial pancreas
Revenues(US$B)
(Yole Développement, September 2017)
Bringing a new artificial organ to market is a
very long and costly project. The average time
of development for such a complex technology is
about 15-25 years in addition to the five to ten
years of testing and regulatory approval. These
gigantic delays explain why few companies have
ever invested in artificial organs, even if the total
available market is humungous. Investors have
to be patient and developers determined to
bring such a technology to market. Ventricular
assist devices form an established market, with
big players such as Abbott and Medtronic, who
ARTIFICIAL HEART AND ARTIFICIAL PANCREAS: READY TO BLOW UP
THE ARTIFICIAL ORGAN MARKET!

ARTIFICIAL ORGAN TECHNOLOGY AND MARKET ANALYSIS 2017
YESTERDAY ARTIFICIAL ORGANS WERE MADE OF MECHANICAL PARTS: TODAY
THEY ARE BASED ON ELECTRONICS: TOMORROW THEY WILL BE SMART
Maybe you have watched a ‘transhumanist’ movie.
Perhaps you’ve had a conversation about whether or
notyouwouldoptforbionicupgradeslikesuperhuman
lung capacity, or an immortal self-contained heart.
You and your friends probably had different opinions,
but concluded that it’s irrelevant because we are far
away from making these choices. Well, it turns out
that the option is only a few years away. Artificial
organs today only have a few sensors. But in the near
future, the next generation of artificial organs will
have a myriad of embedded sensors to monitor the
status of the patient, and more intelligence to take
changes in physiology into account. The software that
pilots these artificial organs must parallel engineering
developments. For now, particularly in artificial
pancreas, a multitude of different algorithms exist,
each of those with advantages and disadvantages,
but all with an internal control law. These span very
simple binary answers and much more complicated
combinations of multiple data from sensors, physical
laws, and precise output calculations all embedded in
a complex, fast algorithm. Next generation algorithms
are in development today and we are expecting
large improvements. New fashionable methods like
machine learning, and deep learning when the data
is available, are entering research through fuzzy logic
algorithms. These methods seem promising and will
allow full automated control of the artificial organ.
This report unravels the different algorithms used
in artificial pancreas and total artificial heart. It also
describes the technical aspects boosting artificial
organ development progress, such as biocompatibility,
batteries and sensors.
respectively bought the two leaders of the field
Thoratec and HeartWare. However the total
artificial heart is still an emerging market, since
the only player has been Syncardia for years. With
the arrival of newcomers, the total artificial heart
market will experience substantial growth with a 15%
CAGR2017-2022
. We expect penetration of the artificial
pancreas to be also very high and fast in the type 1
diabetic population, since the community has wanted
this solution for years. Only Medtronic had an
artificial pancreas system approved by the US Food
and Drug Administration (FDA) in 2017 and none has
a European CE mark. However, many companies are
ready for approval and commercialization, especially
two collaborations: one between Diabeloop, Dexcom
and Cellnovo; and one involving TypeZero, Dexcom
and Tandem.
After decades of development, artificial organ
products are now ready to enter the medical device
market. Yole Développement is uniquely positioned
to provide your company with an understanding of
the revolution that will happen in the next few years.
Embedded software for artificial organs: Types & context
System software Device
drivers
Programming
software
(CAD, CAE)
Operating
System
Malwarere
Utility software
Application software
Database
Spread
sheet
Multimedia
Presentation
Web /Com’
TextTextTextT
Embedded
software
Multimedia
Enterprise
Artificial organs: Developmental cycle and funding sources
Who pays?
• Public research
funding
• Grants
• Associations
• …
• Fund raising
campaign
• Collaborations
• Public grants
• Investors
• Venture capitals
• …
REPORT OBJECTIVES
• Explain the challenges linked
to organ transplantation
and the limits of the current
processes.
• Introduce the technologies
behind the different types
of artificial organs, including
kidneys, livers, lungs, hearts
and pancreas.
• Give an overview of
artificial organ history from
first developments to today,
along with a presentation of
the main players and their
respective technologies.
Who’s providing what?
Who’s working with who?
• Provide market data and
forecasts
• Detail the current
technology’s limits and how
it might evolve in the future.
• Discuss the main challenges
and how artificial organ
companies can overcome
them.
• Focus on artificial organs’
technical aspects: including
batteries, biocompatibility,
sensors, and pumping
systems

Find more
details about
this report here:
MARKET & TECHNOLOGY REPORT
Executive summary 9
Introduction 36
> The problems of organ transplantation
> Our definition of artificial organs
> Permanent vs. temporary implants
> Wearable vs. implantable
Market segmentation 50
> Technological and economic criteria
> Segmentation of the market
Market data and forecasts 2016-2022 57
> Significant moves
> Fundraising and grants
> Market quantification
> Market data and forecasts
> Roadmap
Segment descriptions 72
> Total artificial heart
> Ventricular assist devices
> Artificial pancreas
> Bioartificial pancreas
> Artificial lungs
> Artificial kidney
> Artificial liver
Technical aspects 153
> Biocompatibility
> Batteries
> Sensors
> Pumps
> Connectivity
> Software
Embedded software for artificial organs 166
> Definitions and context
> Ventricular assist devices and total artificial heart
> Artificial pancreas
Supply chain 182
Perspectives – Bionics, 3D bioprinting
and transhumanism 191
Regulations: an overview 214
> Market access for connected medical devices
Conclusions
TABLE OF CONTENTS (complete content on i-Micronews.com)
COMPANIES CITED IN THE REPORT (non exhaustive list)
Abbott, Accellta, Alcon, Alliqua, Amesys, Amplifon, Animas, Aryballe Technologies, Asante, AWAK,
Baxter, Becton Dickinson, Berlin Heart, Betabionics, Bigfoot Biomedical, Bimba, Biofab, Bionic vision
technologies, Bivacor, Breethe inc., Carmat, Cellnovo, Cochlear Ltd, Debiotech, Dedienne, Defymed,
Device Solutions, Dexcom, Diabeloop, Dose safety, Draper, Dreamed, Dualis, Edwards Lifesciences,
Flex, Fresenius, GN ReSound, Google, Grey Innovation, HeartWare, HEF r&d, IBM Watson, Imasonic,
Inreda Diabetic, InSmart, Insulet corporation, Intarcia, Invensense, Jarvik Heart, Johnson and
Johnson, Knowles, Kollmorgen, Lilly, MC3, Medtronic, Memscap, Minifab, Mode AGC, Nanodialysi,
Nano-dimension, Nemaura, Neokidney, Novartis, Novo Nordisk, Numerex, Omron, Organovo,
Paxitech, Pixium Vision, Reliant Heart, Roche, Second Sigh, Senseonics, Siemens, Sintef, Sivantos,
SmartProducts, Sonion, Sonova, St Jude Medical, ST Microelectronics, Starkey, Syncardia, Tandem,
Tandem Life, TDK-Epcos, Techshot, Terumo, Thoratec, Transonic, TypeZero, ViaCyte, Vignal Artru,
Vital Therapies, WAK, Widex, William Demant, WiTricity, Xenios and many more !
AUTHORS
As a Software & Market Analyst, Dr. Yohann
Tschudi is a member of the MEMS & Sensors business
unit at Yole Développement (Yole). Yohann is daily
working with Yole’s analysts to identify, understand
and analyze the role of the software parts within any
semiconductor products, from the machine code to the
highest level of algorithms. Market segments especially
analyzed by Yohann include big data analysis algorithms,
deep/machine learning, genetic algorithms, all coming
from Artificial Intelligence (IA) technologies. After
his thesis at CERN (Geneva, Switzerland) in particle
physics, Yohann developed a dedicated software for
fluid mechanics and thermodynamics applications.
Afterwards, he served during 2 years at the University
of Miami (FL, United-States) as a research scientist in
the radiation oncology department. He was involved
in cancer auto-detection and characterization projects
using AI methods based on images from Magnetic
Resonance Imaging (MRI). During his research career,
Yohann has authored and co-authored more than 10
relevant papers. Yohann has a PhD in High Energy
Physics and a master degree in Physical Sciences from
Claude Bernard University (Lyon, France).
As a Technology & Market Analyst in the
Medical Technologies (MedTech) business
unit at Yole Développement (Yole), Asma
Siari is involved in the development of
technology & market reports as well as the
production of custom consulting projects.
After a Master’s degree in Biotechnologies,
Diagnostic Therapeutics & Management,
Asma serves as Research Assistant at
the Moores Cancer Center (San Diego,
CA). She is a coauthor in two scientific
publications published in the Molecular
Cancer Research Journal. In addition to her
mission at Yole, Asma prepares today her
Advanced Master’s degree in International
Strategy & Marketing BtoB (EM Lyon
Business School, France).
As a Technology & Market Analyst,
Dr. Marjorie Villien works in the
Microfluidic & Medical Technologies
(MedTech) business unit at Yole
Développement, the “More than Moore”
market research and strategy consulting
company. She is a daily contributor to
the development of MedTech activities,
with a dedicated collection of market &
technology reports as well as custom
consulting projects. After spending two
years at Harvard, Dr. Villien served as a
research scientist at INSERM in the field
of MRI & PET imaging. She has spoken at
numerous international conferences and
has authored or co-authored 11 papers
and one patent. Dr. Villien graduated from
Grenoble INP and holds a PhD in physics
& medical imaging.
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www.knowmade.fr
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www.bmorpho.com
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www.piseo.fr

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Our analysts
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and business
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makers
Suppliers: material,
equipment, OSAT,
foundries…
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makers
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and consumer
electronics
Automotive
Medical
systems
Industrial and
defense
Energy

o Yole Développement publishes a comprehensive collection of market & technology reports and patent analysis in:
• MEMS & Sensors
• RF devices & technologies
• Imaging
• Medical technologies (MedTech)
• Photonics
• Advanced packaging
• Manufacturing
• Advanced substrates
• Power electronics
• Batteries and energy management
• Compound semiconductors
• Solid state lighting
• Displays
o You are looking for:
• An analysis of your product market
• A review of your competitors evolution
• An understanding of your manufacturing and production costs
• An understanding of your industry technology roadmap and related IPs
• A clear view on the evolution of the supply chain
The combined team of 60+ experts (PhDs, MBAs, industry veterans…) from Yole Développement, System Plus Consulting and KnowMade, collect information, identify
the trends, the challenges, the emerging markets, the competitive environments and turn it into results to give you a complete picture of your industry landscape.
In the past 19 years, we worked on more than 2 000 projects, interacting with technology professional and high level opinion makers from the main players of the
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o Every year, Yole Développement, System Plus Consulting and Knowmade publish +120 reports. Gain full benefit from our Bundle and Annual Subscription offers.
REPORTS COLLECTION
www.i-Micronews.com

OUR 2017 REPORTS PLANNING (1/2)
MARKET ANDTECHNOLOGY REPORTS byYole Développement
o MEMS & SENSORS
− Acoustic MEMS and Audio Solutions 2017
− 3D Imaging & Sensing 2017
− Microspectrometers Markets and Applications 2017
− Status of the MEMS Industry 2017*
− MEMS & Sensors for Automotive 2017
− High End Inertial Sensors for Defense and Industrial Applications 2017*
− Magnetic Sensors Market and Technologies 2017
− Sensors and Sensing Modules for Smart Homes and Buildings 2017
− Sensing and Display for AR/VR/MR 2017
− MEMS Packaging 2017
− Fingerprint Sensor Applications and Technologies - Consumer Market Focus 2017
o RF DEVICES AND TECHNOLOGIES
− RF Front End Modules and Components for Cellphones 2017
− Advanced RF SiP for Cellphones 2017
− 5G and Beyond (Vol 1): Impact on RF Industry, from Infrastructure to Terminals
2017
− 5G and Beyond (Vol 2): RF Materials Platform, from Infrastructure to Terminals
2017
− RF Technologies for Automotive Applications 2017
− GaN and Si LDMOS Market and Technology Trends for RF Power 2017
o MANUFACTURING
− Glass Substrate Manufacturing 2017
− Equipment & Materials for Fan Out Technology 2017
− Equipment and Materials for 3D TSV Applications 2017
− Emerging Non Volatile Memories 2017*
o MEDTECH
− Status of the Microfluidics Industry 2017
− Solid State Medical Imaging 2017
− Connected Medical Devices: the Internet of Medical Things 2017
− Sensors for Medical Robotics 2017
− Artificial Organs: Market & Technology Analysis 2017
− Organs-on-a Chip 2017
o ADVANCED PACKAGING
− Advanced Substrates Overview 2017
− Status of the Advanced Packaging Industry 2017
− Fan Out Packaging: Market & Technology Trends 2017*
− 3D Business Update: Market & Technology Trends 2017*
− Advanced QFN: Market & Technology Trends 2017**
− Inspection and Metrology for Advanced Packaging Platform 2017**
− MEMS Packaging 2017
− Advanced Packaging for Memories 2017
− Advanced RF SiP for Cellphones 2017
− Power Packaging Market and Technology Trends 2017
− Embedded Die Packaging: Technologies and Markets Trends 2017
o IMAGING & OPTOELECTRONICS
− 3D Imaging & Sensing 2017
− Status of the CMOS Image Sensor Industry 2017*
− Camera Module for Consumer and Automotive Applications 2017*
− Uncooled Infrared Imaging Technology & Market Trends 2017*
− Solid State Medical Imaging 2017
o BATTERY AND ENERGY MANAGEMENT
− Status of Battery Industry for Stationary, Automotive and Consumer Applications
*2016 version still available / **To be confirmed

OUR 2017 REPORTS PLANNING (2/2)
o POWER ELECTRONICS
− Status of Power Electronics Industry 2017*
− Silicon Power Mosfet: Market and Technology Trends 2017
− IGBT Market and Technology Trends 2017
− Power Packaging Market and Technology Trends 2017
− Power SiC 2017: Materials, Devices, and Applications*
− Power GaN 2017: Materials, Devices, and Applications*
− Materials Market Opportunities for Cellphone Thermal Management (Battery
Cooling, Fast Charging, Data Processing, Battery Cooling, etc.) 2017
− Gate Driver Market and Technology Trends 2017
− Power Management ICs Market Quarterly Update 2017
− Power Electronics for Electrical Aircraft, Rail and Buses 2017**
− Thermal Management for LED and Power 2017
o COMPOUND SEMICONDUCTORS
− Power SiC 2017: Materials, Devices, and Applications*
− Power GaN 2017: Materials, Devices, and Applications*
− GaN and Si LDMOS Market and Technology Trends for RF Power 2017
− 5G and Beyond (Vol 2): RF Materials Platform, from Infrastructure to Terminals
2017
− Bulk GaN Substrate Market 2017
o DISPLAYS
− MicroLED Displays 2017
− Display for Augmented Reality, Virtual Reality and Mixed Reality 2017
− Quantum Dots for Display Applications 2017
− Phosphors & Quantum Dots 2017 - LED Downconverters for Lighting & Displays
− Organic Thin Film Transistor 2016: Flexible Displays and Other Applications
− Automotive Lighting 2017 - Technology, Industry and Market Trends
o SOLID STATE LIGHTING
− UV LEDs 2017 - Technology, Manufacturing and Application Trends*
− Horticultural Lighting 2017 - Technology, Industry and Market Trends
− Automotive Lighting 2017 - Technology, Industry and Market Trends*
− Active Imaging and Lidar 2017 (Vol 2) - IR Lighting**
− LED Lighting Module 2017 - Technology, Industry and Market Trends
− IR LEDs and Lasers - Technology Applications and Industry Trends 2017
− Phosphors & Quantum Dots 2017 - LED Downconverters for Lighting & Displays
− MicroLED Displays 2017
− CSP LED Lighting Module 2017
− LED Packaging 2017
− Thermal Management for LED and Power 2017
PATENT ANALYSIS by Knowmade
− Consumer Physics SCiO Molecular Sensor Patent-to-Product Mapping 2017
− Patent Licensing Companies in the Semiconductor Market - Patent Litigation
− Risk and Potential Targets 2017
− MEMS Microphone: Patent Landscape Analysis 2017
− MEMS Microphone: Knowles’ Patent Portfolio Analysis 2017
− Microbolometer: Patents Used in Products 2017
− Microfluidic Technologies for Diagnostic Applications Patent Landscape 2017
− Micropumps: Patent Landscape Analysis 2017
− GaN Technology: Top-100 IP Profiles 2017
− MicroLEDs: Patent Landscape Analysis 2017
− Consumer Physics SCiO Molecular Sensor Patent-to-Product Mapping 2017
− Uncooled Infrared Imaging: Patent Landscape Analysis 2017
− 3D Monolithic Memory: Patent Landscape Analysis 2017
TEARDOWN & REVERSE COSTING by System Plus Consulting
More than 60 teardowns and reverse costing analysis and cost simulation tools to be
published in 2017.*2016 version still available / **To be confirmed

OUR 2016 PUBLISHED REPORTS LIST (1/2)
MARKET AND TECHNOLOGY REPORTS by Yole Développement
o MEMS & SENSORS
− Gas Sensors Technology and Market 2016
− Status of the MEMs Industry 2016
− Sensors for Cellphones and Tablets 2016
− Market and Technology Trends of Inkjet Printheads 2016
− Sensors for Biometry and Recognition 2016
− Silicon Photonics 2016
o IMAGING & OPTOELECTRONICS
− Status of the CMOS Image Sensor Industry 2016
− Uncooled Infrared Imaging Technology & Market Trends 2016
− Imaging Technologies for Automotive 2016
− Sensors for Drones & Robots: Market Opportunities and Technology Evolution 2016
o MEDTECH
− BioMEMS 2016
− Point of Care Testing 2016: Application of Microfluidic Technologies
o ADVANCED PACKAGING
− Embedded Die Packaging: Technology and Market Trends 2017
− 2.5D & 3D IC TSV Interconnect for Advanced Packaging: Business Update 2016
− Fan-Out: Technologies and Market Trends 2016
− Fan-In Packaging: Business update 2016
− Status and Prospects for the Advanced Packaging Industry in China 2016
o MANUFACTURING
− Thin Wafer Processing and Dicing Equipment Market 2016
− Emerging Non Volatile Memories 2016
o COMPOUND SEMICONDUCTORS
− Power GaN 2016: Epitaxy and Devices, Applications and Technology Trends
− GaN RF Devices Market: Applications, Players, Technology and substrates 2016
− Sapphire Applications & Market 2016: from LED to Consumer Electronics
− Power SiC 2016: Materials, Devices, Modules, and Applications
o LED
− UV LED Technology, Manufacturing and Applications Trends 2016
− OLED for Lighting 2016 – Technology, Industry and Market Trends
− Automotive Lighting: Technology, Industry and Market Trends 2016
− Thermal Management Technology and Market Perspectives in Power Electronics and
LEDs 2017
− Organic Thin Film Transistor 2016: Flexible Displays and Other Applications
− Sapphire Applications & Market 2016: from LED to Consumer Electronics
− LED Packaging 2017: Market, Technology and Industry Landscape
o POWER ELECTRONICS
− Power Electronics for EV/HEV 2016: Market, Innovations and Trends
− Status of Power Electronics Industry 2016
− Passive Components Technologies and Market Trends for Power Electronics 2016
− Power SiC 2016: Materials, Devices, Modules, and Applications
− Power GaN 2016: Epitaxy and Devices, Applications, and Technology Trends
− Inverter Technologies Trends & Market Expectations 2016
− Opportunities for Power Electronics in Renewable Electricity Generation 2016
− Thermal Management Technology and Market Perspectives in Power Electronics and
LEDs 2017
− GaN RF Devices Market: Applications, Players, Technology and substrates 2016
o BATTERY AND ENERGY MANAGEMENT
− Beyond Li-ion Batteries: Present and Future Li-ion Technology Challengers 2016
− Stationary Storage and Automotive Li-ion Battery Packs 2016
− Opportunities for Power Electronics in Renewable Electricity Generation 2016

OUR 2016 PUBLISHED REPORTS LIST (2/2)
PATENT ANALYSIS by Knowmade
− Microbattery Patent Landscape Analysis
− Miniaturized Gas Sensors Patent Landscape Analysis
− 3D Cell Culture Technologies Patent Landscape
− Phosphors and QDs for LED Applications Patent Landscape
− TSV Stacked Memory Patent Landscape
− Fan-Out Wafer Level Packaging Patent Landscape Analysis
TEARDOWN & REVERSE COSTING by System Plus Consulting
More than 45 teardowns and reverse costing analysis and cost simulation tools published
in 2016.
MORE INFORMATION
o All the published reports from the Yole Group of Companies are available on our website
www.i-Micronews.com.
o Ask for our Bundle and Annual Subscription offers: With our bundle offer, you choose the
number of reports you are interested in and select the related offer. You then have up to 12
months to select the required reports from the Yole Développement, System Plus Consulting
and KnowMade offering. Pay once and receive the reports automatically (multi-user format).
Contact your sales team according to your location (see the last slide).

MICRONEWS MEDIA
o About Micronews Media
To meet the growing demand for market,
technological and business information,
Micronews Media integrates several tools able
to reach each individual contact within its
network.We will ensure you benefit from this.
ONLINE ONSITE INPERSON
@Micronews e-newsletter
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product/brand visibility.They
are also an efficient way to
adapt with the demands of the
times and to evolve an effective
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Brand visibility, networking
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Today's technology makes it
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Contacts: CamilleVeyrier (veyrier@yole.fr) and Clotilde Fabre (fabre@yole.fr), Marketing & Communication Project Managers.

CONTACT INFORMATION
o CONSULTING AND SPECIFIC ANALYSIS
• North America: Steve LaFerriere, Director of Northern America Business Development
Email: laferriere@yole.fr – +1 31 06 008 267
• Japan & Rest of Asia: Takashi Onozawa, General Manager, Asia Business Development
Email: onozawa@yole.fr - +81 3 4405 9204
• Greater China: Mavis Wang, Director of Greater China Business Development
Email: wang@yole.fr - +886 979 336 809
• RoW: Jean-Christophe Eloy, CEO & President, Yole Développement
Email eloy@yole.fr - +33 4 72 83 01 80
o REPORT BUSINESS
• North America: Steve LaFerriere, Director of Northern America Business Development
Email: laferriere@yole.fr – +1 31 06 008 267
• Europe: Lizzie Levenez, EMEA Business Development Manager
Email: levenez@yole.fr - +49 15 123 544 182
• Rest of Asia: Takashi Onozawa, General Manager, Asia Business Development
Email: onozawa@yole.fr - +81 3 4405 9204
• Japan & Asia: Miho Othake, Account Manager
Email: ohtake@yole.fr - +81 3 4405 9204
• Greater China: Mavis Wang, Director of Greater China Business Development
Email: wang@yole.fr - +886 979 336 809
o FINANCIAL SERVICES
• Jean-Christophe Eloy, CEO & President
Email: eloy@yole.fr - +33 4 72 83 01 80
o GENERAL
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