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From Technologies to Market
Sample
Neurotechnologies and
brain computer interface
Market and Technology analysis
2018
2
Abbott,Ad-tech,Advanced Brain Monitoring,AdvaStim,AIST,Aleva Neurotherapeutics,Alphabet,Amazon,Ant Group,ArchiMed,
Artinis Medical Systems,Atlas Neuroengineering,ATR, Beijing Pins Medical, BioSemi, Biotronik, Blackrock Microsystems, Boston
Scientific, Brain products, BrainCo, Brainscope, Brainsway, Cadwell, Cambridge Neurotech, Caputron, CAS Medical Systems, CEA,
Circuit Therapeutics, Cirtec Medical, Compumedics, Cortec, CVTE, Cyberonics, Deep Brain Innovations, Deymed, Dixi Medical,
DSM, EaglePicherTechnologies, Electrochem Solutions, electroCore, Elmotiv, Endonovo Therapeutics, EnerSys, Enteromedics,
Evergreen MedicalTechnologies, Facebook, Flow, Foc.us, G.Tec, Galvani Bioelectronics, General Electric, Geodesic, Glaxo Smith
Klein, Halo Neurosciences, Hamamatsu, Helius Medical,Technologies, Hitachi, iBand+, IBM Watson, IMEC, Integer, Integra,
InteraXon, ISS, Jawbone, Kernel, LivaNova, Mag and More, Magstim, Magventure, Mainstay Medical, Med-el Elektromedizinische
Geraete, Medtronic, Micro Power Electronics, Micro Systems Technologies, Micromed, Microsoft, MindMaze, Mitsar, MyBrain
Technologies, Natus, NEC, Nemos, Nervana, Neurable, Neuralink, NeuroCare, NeuroElectrics, NeuroLutions, NeuroMetrix,
Neuronetics, Neuronetics, Neuronexus, Neuropace, Neuros Medical, Neuroscan, NeuroSigma, NeuroSky, Neurosoft, Neurostar,
Neurowave, Nevro, Nexeon, Nexstim, Nielsen, Nihon Kohden, Nirox, Nonin Medical, Nuvectra, Olympus, Ornim, Oscor,
Pacesetter, Panasonic, Paradromics, Philips, Plexon, PMT Corporation, RetroSense, Rhythm, Ripple, Rythm Dreem, Samsung,
SceneRay, Second Sight Medical, Sensomedical, Setpoint Medical, Shimadzu, Siemens, Sony, Sorin Group, Soterix Medical, SPR
Therapeutics, Stim Wave,Teijin,Thync,Toyota,Verily,VieLight,Vygon, Ximedica,Ybrain,
And many more !!
LIST OF COMPANIES MENTIONED IN THIS REPORT
©2018 | www.yole.fr | Neurotechnologies and brain computer interface
240+ slides of market and technology analysis
Information gathered through direct discussions with technology developers, end-users and key opinion leaders
3
Biographies & contacts
ABOUT THE AUTHORS
Jérôme Mouly
Dr. Marjorie Villien
As a Technology & Market Analyst, Dr. Marjorie Villien is member of the Medical Technologies business unit at Yole Développement (Yole). She is a daily
contributor to the development of these activities with a dedicated collection of market & technology reports as well as custom consulting projects.
After spending two years at Harvard and prior Yole, Marjorie served as a research scientist at INSERM.
Marjorie Villien is graduated from Grenoble INP and holds a PhD in physics & medical imaging.
Email: villien@yole.fr
Jerôme Mouly serves as a Technology & Market Analyst specialized in microtechnologies for biomedical & medical imaging applications at Yole Développement
(Yole). Since 2000, Jérôme has participated in more than 100 marketing and technological analyses for industrial groups, start-ups and institutes related to
semiconductor & medical technologies industry. Jérôme holds a Master of Physics from the University of Lyon.
Email: mouly@yole.fr
KnowMade’s team realized the patent analysis:
Dr Coralie Le Greneur
Dr Coralie Le Greneur works for Knowmade in the field of Biotechnology and Life Sciences. She holds a PhD in Molecular Biology from the University of Nice
Sophia- Antipolis (France). She also holds the International Industrial Studies Diploma in Patents from the CEIPI, Strasbourg (France).
Email: coralie.legreneur@knowmade.fr
Dr. Brice Sagot
Dr. Brice Sagot is COO and cofounder of Knowmade. He is leading the Biotechnology and Life Sciences department. He holds a PhD in molecular biology from the
University of Nice Sophia-Antipolis, France.
Email: brice.sagot@knowmade.fr
4
OBJECTIVES OF THIS REPORT
• Explain the challenges linked to neurotechnologies, and their current/ future applications
• Offer a technical and economic segmentation of the neurotechnologies field: neurosensing, neurostimulation, and
brain computer interface (BCI)
• Deliver an overview of neurotechnologies’ main players and their respective technologies
• Furnish market data and forecasts for the period 2017 - 2035, and market dynamics for each segment
• Provide neurotechnology roadmaps and an overview of the latest innovations in each segment
• Understand the most active companies through a comprehensive patents list for neurostimulation and
neurosensing
5
WHO SHOULD BE INTERESTED BY THIS REPORT?
o Pharmaceutical and medical device companies:
• To understand what is state of the art in
neurotechnology
• To identify the different players across the supply
chain
• To get a list of selected players in the field of
neurotechnology both in the market and in
development
• To understand behavior evolution and identify
new business models
• To identify competitors and targets for
collaborations or M&A
o Equipment & Material suppliers:
• To understand the technical evolution of
neurotechnology devices.
• To identify business opportunities and prospects
o R&D players:
• To understand new challenges in
neurotechnology
o Medical devices outsourcing companies:
• To have a broad overview of all neurotechnology
applications & markets
• To identify new markets
• To monitor and benchmark potential
competitors
• To understand behavior evolution
• To identify the key challenges linked to hardware
in the field of neurotechnology
o Financial & Strategic investors:
• To understand the potential for neurotechnology
devices in the consumer and healthcare
industries
• To know the latest trends within the industry
• To get a list of players in the field of
neurotechnology and their activities
6
TABLE OF CONTENTS
• Executive Summary 10
• Introduction 55
• How does the brain work?
• Neurological disorders
• Brain Initiative
• Scope of the report
• Segmentation of the Neurotechnology Market 67
• Technological and behavioral/economical criteria
• Segmentation
• Market Analysis 71
• Mergers and acquisitions
• Fundraising analysis
• Market data and forecasts 2017-2023
• Neurotechnology ecosystems
• IOMT in the neurotechnology business
• Roadmaps
• Forecasts 2017-2035 using the model of the DNA sequencing history
• Neurosensing 90
• Main players and market share
• Market data and forecasts 2017 – 2023: system level and electrodes level, by
technology and by application
• EEG value chain
• Main technologies and roadmaps
• Patent landscape by KnowMade
• Company profiles
• Neurostimulation 153
• Main players and market share
• Market data and forecasts 2017 – 2023 by technology (DBS, SCS, VNS, TMS,
TDCS, etc.) and by application (clinical, research, consumer)
• Main technologies and roadmaps
• Patent landscape by KnowMade
• Company profiles
• Brain Computer Interface 204
• Main players
• Market data and forecasts 2017 – 2023 by applications
• Main technologies and roadmaps
• Company profiles
• Supply Chain Analysis 227
• General Conclusions 233
• Annex - Patent Landscape Methodology 238
7
INTRODUCTION TO NEUROTECHNOLOGY
How does the brain work? (1/2)
Most of the
technologies
aiming at
interacting with
the brain target
the electrical
signaling
pathway of the
neurons
• The brain is made of a lot of different types of cells:
• Neurons : electrically excitable cells that receive, process, and transmit information
through electrical and chemical signals
• Microglia : immune system
• Oligodendrocytes : provide support and insulation to axons
• Astrocytes : variety of tasks, from axon guidance and synaptic support, to the
control of the blood brain barrier and blood flow
• The axon of the neuron is responsible for conveying an action potential from
the cell body to the axon terminus. An action potential is an electrical signal
resulting from a sudden, transient change in membrane potential.
8
INTRODUCTION TO NEUROTECHNOLOGY
How does the brain work? (2/2)
Electrical events
propagate the
signal within a
neuron and
chemical
processes
transmit the
signal from one
neuron to
another
• When an action potential reaches an axon terminal it triggers the release of neurotransmitters into the synaptic cleft
which diffuses and binds receptors on the postsynaptic neuron.
• Sufficient binding will cause the postsynaptic neuron to “fire”.
• There are two kinds of neurotransmitters :
• Excitatory neurotransmitters stimulate the brain.
• Inhibitory neurotransmitters calm the brain and help create balance.
9
INTRODUCTION TO NEUROTECHNOLOGY
Neurological disorders
Up to 1 billion
people, nearly
one in six of
the world's
population,
suffer from
neurological
disorders
-
10
20
30
40
50
60
70
80
90
100
Millionspeopleaffected
Worldwide prevalence of most neurological disorders
(in millions people affected)
Trauma Infections Degeneration
Psychiatric
disorders
Tumors Vascular
Non-
psychiatric
disorders
350M 1,140M
Source:WHO
10
INTRODUCTION TO NEUROTECHNOLOGY
Scope of the report
Scope:
Neurotechnologies
directly interacting
with patients
Not included in the scope of this report are
neurotechnologies based on medical imaging
systems not directly interacting with the patient
(MRI, MEG, PET, etc.), cochlear implants and
retinal prosthesis.
Included in this report are neurotechnologies
which directly interact with/touch the patient,
such as neurosensing technologies (EEG, ECoG,
NIRS, etc.), neurostimulation (DBS,VNS,TDCS,
etc.) and brain computer interfaces.
11
SEGMENTATION OF THE NEUROTECHNOLOGY MARKET
Invasive Non invasive Invasive Non invasive
Electrical Light Magnetic Ultrasound
Sensing
Clinical
Electro-corticography,
Neural probes
Electro-
encephalography
Near infrared
spectroscopy
Stimulation
Neurostimulation Optogenetics
Transcranial
magnetic
stimulation
Focused
ultrasounds
Transcranial direct
current stimulations
Near Infrared stimulation
Consumer
Vagus nerve
stimulation
Actuation
Clinical
Brain computer interface
Consumer
Invasiveness
Technology
Technological
criteriaBehavioral
criteria
:Technologies not available in clinics yet
Segment 2 : Neurostimulation
Segment 1 : Neurosensing
Segment 3 : Brain Computer Interface
Aimofthe
system
Users
12
NEUROTECHNOLOGY ECOSYSTEM
Medical device
outsourcing
manufacturers
Brain computer
interface
Neurostimulation
Neurosensing
Electrode
manufacturers
13
CONTENT OF THE REPORT
Introduction
14
CONTENT OF THE REPORT
Market analysis and segmentation
15
CONTENT OF THE REPORT
Neurosensing
16
CONTENT OF THE REPORT
Neurostimulation
17
CONTENT OF THE REPORT
Brain Computer Interface
18
RELATED REPORTS
Who has never dreamt of taking control of
its environment without using the hands, just
thinking? And if these assumptions looking like
science fiction are turning to reality thanks to
neurotechnologies!
For a long time neurosciences were an exclusive
domain of healthcare, and technologies
associated were serving two main applications:
neurostimulation and neurosensing. In early
2000’s the concept of Brain Computer Interface
(BCI) emerged with the strong objective to use
brain and peripheral nerve information to the
benefit of patients. More recently, BCI got the
objective not only to serve the medical sector,
but to exploit brain signal for a broad range of
applications in industrial, military and consumer
fields. This has surely caught the attention of
ambitious people like Elon Musk who founded
Neuralink in this domain in 2017 or Bryan Johnson
who invested $100M in his company Kernel.
Web giants, with companies such as Google,
Facebook and Microsoft are also watching these
new technologies carefully. Facebook is strongly
involved in project of “typing-by-brain” as a silent-
speech interface, while Microsoft is publishing
patents on “mind control” that allow users to
operate apps using their mind without gesture.
Conjunction of neurosciences, advanced micro-
technologies and rapid adoption of wearables
lead to the emergence of innovative start-up
companies and number of initiatives supported by
public or private organizations. In the last 3 to 4
years, a wave of fundraising reached a cumulative
$300M in BCI companies accompanied by national
initiatives like the Obama’s Brain Initiative project
supported by US government inspired by the
success of the Human Genome Project. If we take
the model of the DNA sequencing history, given
that researches are going faster today thanks to
computer science, it wouldn’t be surprising to see
the discovery of a groundbreaking technology to
record brain signals before 2030.
This report is covering the 3 main segments
of neurotechnologies (neurostimulation,
neurosensing and BCI), the dynamic of the market
through fundraisings, merger & acquisition as
well as comprehensive roadmaps of product
developments.
NEUROTECHNOLOGIES AND BRAIN COMPUTER
INTERFACE
Market & Technology report - February 2018
WILL NEUROTECHNOLOGIES FOLLOWING THE PATH OF DNA
SEQUENCING AND REVOLUTIONIZING NOT ONLY MEDICINE
BUT THE ENTIRE SOCIETY?
How are neurotechnologies unraveling the mystery of our brain and opening new business opportunities?
KEY FEATURES OF THE REPORT
Get the sample of the report
on www.i-Micronews.com
• Introduction to neurotechnologies
and market landscapes
•	Comprehensive market analysis
of each segment, covering
neurostimulation, neurosensing
and brain computer interface
•	Fundraising analysis, investments
and acquisitions
•	Patent landscape analysis of
neurostimulation and neurosensing
•	Market data and forecasts for 2017
– 2023 with a tentative forecast
until 2035, and 2017 market share
for each segment
•	Main technologies and roadmaps
•	Company profiles with technology
descriptions
OBJECTIVES OF THE REPORT
•	Explain the challenges linked to
neurotechnologies, and their
current and future applications
• Offer a technical and
economic segmentation of
the neurotechnologies field:
neurosensing, neurostimulation,
brain computer interface
• Give an overview of
neurotechnologies main players
and their respective technologies.
• Furnish market data and forecasts
for the period 2017-2035, and
market dynamics in each segments.
• Provide neurotechnology
roadmaps and latest innovation in
the different segments
• Discover the most active
companies through comprehensive
list of patents in neurostimulation
and neurosensing
1980 1990 2000 2010 2020 2030 2040
Final sequencing
mapping of the
human genome
Human genome project
($3B for 15 years
international project) Human brain project
($5B for 12 years
project)
Illumina
Next-generation
sequencing
Third-generation
sequencing
100B
1B
10M
100K
1K
10
Speedofsequencing(kbytes/day)
Speedofneuronreading
(singleneuronsrecorded/seconds)
Groundbreaking
discovery to record
brain signals?
(Yole Développement, February 2018)
NEUROTECHNOLOGIES: A $4.6B MARKET IN 2017 MAINLY DRIVEN BY THE
NEUROSTIMULATION SEGMENT
The neurotechnologies market is expected to
reach $7.4B in 2023, with a CAGR2017-2023
of 8.3%.
Neurostimulation is representing the major part
of this market whose key players are giant medical
device companies Medtronic, Boston Scientific or
Abbott (formerly Saint-Jude Medical) taking most
of the market shares. However market shares are
slightly moving due to technology improvement
Neurotechnologies are following the DNA sequencing history
This report includes global trends
in patent application identified by
KnowMade but does not include an
in-depth analysis of any patents.
NEUROTECHNOLOGIES AND BRAIN COMPUTER INTERFACE
THE MUTATION OF THE NEUROTECHNOLOGY BUSINESS IS GUIDED BY TECHNICAL
PROGRESS IN THE SENSING AND STIMULATION DOMAIN AS ATTEST BY THE PATENT
LANDSCAPE EVOLUTIONS
The rapid development of neurotechnologies is
a combination of different factors: technology
availability, miniaturization, connectivity, power and
rapid adoption of wearables contributes to innovation
at sensor and system level.
A one shot EEG procedure at hospital and use of wet
electrodes is acceptable to the patient. However,
development of dry electrodes is bringing more
comfort and application for long time monitoring
and BCI. As an example, g.tec unveiled its RecoveriX
system, an EEG cap with dry active electrodes for
training session of patients in rehabilitation. Another
trend for brain signal monitoring is the EEG wireless
headsets. The CerebAir headset of Nihon Kohden has
been developed in close collaboration with IMEC and
Holst Center. The platform developed at IMEC is also
serving consumer markets for emotion detection. It
is worth noting that new electrodes and ergonomic
systems give more comfort to users, enabling a
broader use of headset in consumer or industrial
applications. Companies like Muse and Emotiv are
taking benefits of advanced technologies to offer head-
bands and headsets that capture user emotions. Other
challenges in the neuroscience landscape concerns
implanted devices like deep brain stimulators and the
battery lifetime, requiring regular surgeries. Boston
Scientific has invested to develop a new battery for
DBS neurostimulator that more than double current
neurostimulator lifetime.
in neurostimulation with smaller players bringing
new technologies like Neuropace and its closed loop
neurostimulator or ElectroCore for the treatment of
headache using non-invasive vagus nerve stimulation.
But implanted neurostimulators such as spinal cord
stimulators for the treatment of pain or deep brain
stimulators in the treatment of Parkinson’s disease
and epilepsy are still representing a large part of the
product sold.
Comparatively, neurosensing market for diagnostics
and research is a more mature market, and
quite conservative when considering Electro-
Encephalography (EEG) in clinical applications.
Research companies like Brain Products and g.tec are
currently very active to develop next generation of
electrodes and systems to answer the strong demand
for BCI applications. BCI is forecasted to have the
strongest growth for the next decades,
The report is presenting market data from 2017 to
2035 and the key players on each neurotechnology
segment. It presents the fast growing segment of BCI
applications, neurostimulation market with detailed
stimulating technologies and related players, and
neurosensing market focusing on clinical EEG for
diagnostics and EEG for research.
Market data and forecasts in value 2017-2035
4
2017 2023 2029 2035
$38.4B
$13.7B
$7.4B
$4.6B
CAGR2017-2023=8.3%
CAGR2023-2029=10.8%
CAGR2029-2035=18.8%Neurostimulation
Neurosensing
BCI
Neurosensing roadmap
(Yole Développement, February 2018)
3
Gaming,
sports
Wireless
Rehab, sleep
monitoring
1920 2000 Today2010
Consumer
Consumer/Healthcare
research
Healthcare
Wired EEG –
Wet electrodes
Dry Electrode
based EEG
Headset EEG
2020 2030
EEG: Electro-Encephalography
(Yole Développement, February 2018)
Find more
details about
this report here:
MARKET  TECHNOLOGY REPORT
COMPANIES CITED IN THE REPORT (non exhaustive list)
Abbott, Ad-tech, Advanced Brain Monitoring, AdvaStim, AIST, Aleva Neurotherapeutics, Alphabet,
Amazon, Ant Group, ArchiMed, Artinis Medical Systems, Atlas Neuroengineering, ATR, Beijing Pins
Medical, BioSemi, Biotronik, Blackrock microsystems, Boston Scientific, Brain products, BrainCo,
BrainCo, Brainscope, Brainsway, Cadwell, Cambridge Neurotech, Caputron, CAS Medical Systems,
CEA, Circuit therapeutics, Cirtec Medical, Compumedics, Cortec, CVTE, Cyberonics, Deep
Brain Innovations, Deymed, Dixi Medical, DSM, EaglePicher Technologies, Electrochem solutions,
ElectroCore, Elmotiv, Endonovo therapeutics, EnerSys, Enteromedics, Evergreen medical technologies,
Facebook, Flow, Foc.us, g.tec, Galvani bioelectronics, General electric, Geodesic, Glaxo Smith Klein,
Halo Neuroscience, Halo Neurosciences, Hamamatsu, Helius Medical, Technologies, Hitachi, iBand+,
IBM Watson, IMEC, Integer, Integra, InteraXon, ISS, Jawbone, Kernel, LivaNova, Mag and More,
Magstim, Magventure, Mainstay Medical, Med-el elektromedizinische geraete, Medtronic, Micro
power electronics, Micro Systems Technologies, Micromed, Microsoft, MindMaze, Mitsar, MyBrain
Technologies, Natus, NEC, Nemos, Nervana, Neurable, Neuralink, NeuroCare, NeuroElectrics,
NeuroLutions, NeuroMetrix, Neuronetics, Neuronetics, Neuronexus, NeuroPace, Neuropace,
Neuros Medical, Neuroscan, NeuroSigma, NeuroSky, Neurosoft, Neurostar, Neurowave, Nevro,
Nexeon, Nexstim, Nielsen, Nihon Kohden, Nirox, Nonin Medical, Nuvectra, Olympus, Ornim,
Oscor, Pacesetter, Panasonic, Paradromics, Philips, Plexon, PMT corporation, RetroSense, Rhythm,
Ripple, Rythm Dreem, Samsung, SceneRay, Second sight medical, Sensomedical, Setpoint Medical,
Shimadzu, Siemens, Sony, Sorin Group, Soterix Medical, SPR Therapeutics, Stim Wave, Teijin, Thync,
Toyota, Verily, VieLight, Vygon, Ximedica, Ybrain, and many more !
AUTHORS
Jerôme Mouly serves as a Technology
 Market Analyst specialized in
microtechnologies for biomedical 
medical imaging applications at Yole
Développement (Yole). Since 2000,
Jérôme has participated in more than 100
marketing and technological analyses for
industrial groups, start-ups and institutes
related to semiconductor  medical
technologies industry.
Jérôme holds a Master of Physics from the
University of Lyon.

Executive summary 	 10
Introduction	55
 How does the brain work?
 Neurological disorders
 Brain initiative
 Scope of the report
Segmentation of the neurotechnologies market	 67
 Technological and behavioral/economical criteria
 Segmentation
Market analysis	 71
 Mergers and acquisitions
 Fundraising analysis
 Market data and forecasts 2017-2023
 Neurotechnologies ecosystem
 IOMT in the neurotechnology business
 Roadmaps
 Forecasts 2017-2035 using the model of the DNA
sequencing history
Neurosensing	90
 Main players and market share
 Market data and forecasts 2017 – 2023: system level and
electrodes level, by technologies and by applications
 EEG value chain
 Main technologies and roadmaps
 Patent landscape
 Company profiles
Neurostimulation	153
 Main players and market share
 Market data and forecasts 2017 – 2023 by technologies
(DBS, SCS, VNS, TMS, TDCS, etc.) and by applications
(clinical, research, consumer)
 Main technologies and roadmaps
 Patent landscape
 Company profiles
Brain computer interface	 204
 Main players
 Market data and forecasts 2017 – 2023
by applications
 Main technologies and roadmaps
 Company profiles	
Supply chain analysis	 227
General conclusions	 233
Annex - Patent landscape methodology 	 238
TABLE OF CONTENTS (complete content on i-Micronews.com)
As a Technology  Market Analyst,
Dr. Marjorie Villien is member of
the Medical Technologies business unit at
Yole Développement (Yole). She is a daily
contributor to the development of these
activities with a dedicated collection of
market  technology reports as well as
custom consulting projects.
After spending two years at Harvard and
prior Yole, Marjorie served as a research
scientist at INSERM. Marjorie Villien is
graduated from Grenoble INP and holds a
PhD in physics  medical imaging.
RELATED REPORT
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• Medical Robotics Technology  Market
Analysis 2017
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Business Models 2017
• BioMEMS: Microsystems for Healthcare
Applications 2016
Find all our reports on
www.i-micronews.com
Dr Coralie Le Greneur works for
Knowmade in the field of Biotechnology and
Life Sciences. She holds a PhD in Molecular
Biology from the University of Nice Sophia-
Antipolis (France). She also holds the
International Industrial Studies Diploma in
Patents from the CEIPI, Strasbourg (France).
This activity in neurosciences is reflected by a
huge number of patent publications. Neurosensing
accounts for 16,000+ published over a period
of 75 years, 25% of whom in the last decade.
Players in consumer electronics like Panasonic are
holding patent on EEG headset, while players in
automotive markets like Toyota are surprisingly
holding 10s of patents on EEG systems.
Roadmaps of development and availability are
available in the report. Technology trends of the
report describes how the miniaturization and
silicon technologies contributes to manufacturing of
invasive probes for local field potential measurement.
The report is also describing patent landscape and
analysis in both sensing and stimulating devices,
highlighting the most active patent assignees and
their involvement in the neurotechnology field.
Dr. Brice Sagot is COO and co-
founder of Knowmade. He is leading the
Biotechnology and Life Sciences department.
He holds a PhD in molecular biology from
the University of Nice Sophia-Antipolis,
France.
KnowMade’s team realized the patent
analysis:
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signing the purchase order which mentions “I hereby accept
Yole’s Terms and Conditions of Sale”.
“Buyer”: Any business user (i.e. any person acting in the course
of its business activities, for its business needs) entering into the
following general conditions to the exclusion of consumers acting
in their personal interests.
“Contracting Parties” or “Parties”: The Seller on the
one hand and the Buyer on the other hand.
“Intellectual Property Rights” (“IPR”) means any
rights held by the Seller in its Products, including any patents,
trademarks, registered models, designs, copyrights, inventions,
commercial secrets and know-how, technical information,
company or trading names and any other intellectual property
rights or similar in any part of the world, notwithstanding the fact
that they have been registered or not and including any pending
registration of one of the above mentioned rights.
“License”: For the reports and databases, 3 different licenses
are proposed. The buyer has to choose one license:
• One user license: one person at the company can use the report.
• Multi-user license: the report can be used by unlimited users
within the company. Subsidiaries and Joint-Ventures are not
included.
• Corporate license: purchased under “Annual Subscription”
program, the report can be used by unlimited users within the
company. Joint-Ventures are not included.
“Products”: Depending on the purchase order, reports or
database on MEMS, CSC, Optics/MOEMS, Nano, bio… to
be bought either on a unit basis or as an annual subscription.
(i.e. subscription for a period of 12 calendar months). The
annual subscription to a package (i.e. a global discount based
on the number of reports that the Buyer orders or accesses
via the service, a global search service on line on I-micronews
and a consulting approach), is defined in the order. Reports are
established in PowerPoint and delivered on a PDF format and the
database may include Excel files.
“Seller”: Based in Lyon (France headquarters), Yole
Développement is a market research and business development
consultancy company, facilitating market access for advanced
technology industrial projects. With more than 20 market
analysts, Yole works worldwide with the key industrial companies,
RD institutes and investors to help them understand the markets
and technology trends.
1. SCOPE
1.1 The Contracting Parties undertake to observe the following
general conditions when agreed by the Buyer and the Seller.
ANY ADDITIONAL, DIFFERENT, OR CONFLICTING
TERMS AND CONDITIONS IN ANY OTHER DOCUMENTS
ISSUED BY THE BUYER AT ANY TIME ARE HEREBY
OBJECTED TO BY THE SELLER, SHALL BE WHOLLY
INAPPLICABLE TO ANY SALE MADE HEREUNDER AND
SHALL NOT BE BINDING IN ANY WAY ON THE SELLER.
1.2 This agreement becomes valid and enforceable between the
Contracting Parties after clear and non-equivocal consent
by any duly authorized person representing the Buyer. For
these purposes, the Buyer accepts these conditions of sales
when signing the purchase order which mentions “I hereby
accept Yole’s Terms and Conditions of Sale”. This results in
acceptance by the Buyer.
1.3 Orders are deemed to be accepted only upon written
acceptance and confirmation by the Seller, within [7 days] from
the date of order, to be sent either by email or to the Buyer’s
address. In the absence of any confirmation in writing, orders
shall be deemed to have been accepted.
2. MAILING OF THE PRODUCTS
2.1 Products are sent by email to the Buyer:
• within [1]
month from the order for Products already
released; or
• within a reasonable time for Products ordered prior to
their effective release. In this case, the Seller shall use its best
endeavours to inform the Buyer of an indicative release date
and the evolution of the work in progress.
2.2 Some weeks prior to the release date the Seller can propose
a pre-release discount to the Buyer
The Seller shall by no means be responsible for any delay in
respect of article 2.2 above, and including incases where a
new event or access to new contradictory information would
require for the analyst extra time to compute or compare
the data in order to enable the Seller to deliver a high quality
Products.
2.3 The mailing of the Product will occur only upon payment
by the Buyer, in accordance with the conditions contained
in article 3.
2.4. The mailing is operated through electronic means either by
email via the sales department or automatically online via an
email/password. If the Product’s electronic delivery format
is defective, the Seller undertakes to replace it at no charge
to the Buyer provided that it is informed of the defective
formatting within 90 days from the date of the original
download or receipt of the Product.
2.5 The person receiving the Products on behalf of the Buyer
shall immediately verify the quality of the Products and their
conformity to the order. Any claim for apparent defects or
for non-conformity shall be sent in writing to the Seller within
8 days of receipt of the Products. For this purpose, the Buyer
agrees to produce sufficient evidence of such defects. .
2.6 No return of Products shall be accepted without prior
information to the Seller, even in case of delayed delivery.
Any Product returned to the Seller without providing prior
information to the Seller as required under article 2.5 shall
remain at the Buyer’s risk.
3. PRICE, INVOICING AND PAYMENT
3.1 Prices are given in the orders corresponding to each Product
sold on a unit basis or corresponding to annual subscriptions.
They are expressed to be inclusive of all taxes. The prices
may be reevaluated from time to time. The effective price is
deemed to be the one applicable at the time of the order.
3.2 Yole may offer a pre release discount for the companies willing
to acquire in the future the specific report and agreeing on the
fact that the report may be release later than the anticipated
release date. In exchange to this uncertainty, the company will
get a discount that can vary from 15% to 10%.
3.3 Payments due by the Buyer shall be sent by cheque payable to
Yole Développement, credit card or by electronic transfer to
the following account:
HSBC, 1 place de la Bourse 69002 Lyon France
Bank code: 30056
Branch code: 00170
Account n°: 0170 200 1565 87
BIC or SWIFT code: CCFRFRPP
IBAN: FR76 3005 6001 7001 7020 0156 587
To ensure the payments, the Seller reserves the right to request
down payments from the Buyer. In this case, the need of down
payments will be mentioned on the order.
3.4 Payment is due by the Buyer to the Seller within 30 days
from invoice date, except in the case of a particular written
agreement. If the Buyer fails to pay within this time and fails
to contact the Seller, the latter shall be entitled to invoice
interest in arrears based on the annual rate Refi of the «BCE»
+ 7 points, in accordance with article L. 441-6 of the French
Commercial Code. Our publications (report, database, tool...)
are delivered only after reception of the payment.
3.5 In the event of termination of the contract, or of misconduct,
during the contract, the Seller will have the right to invoice
at the stage in progress, and to take legal action for damages.
4. LIABILITIES
4.1 The Buyer or any other individual or legal person acting on
its behalf, being a business user buying the Products for its
business activities, shall be solely responsible for choosing the
Products and for the use and interpretations he makes of the
documents it purchases, of the results he obtains, and of the
advice and acts it deduces thereof.
4.2 The Seller shall only be liable for (i) direct and (ii) foreseeable
pecuniary loss, caused by the Products or arising from a
material breach of this agreement
4.3 In no event shall the Seller be liable for:
a) damages of any kind, including without limitation, incidental
or consequential damages (including, but not limited to,
damages for loss of profits, business interruption and loss of
programs or information) arising out of the use of or inability
to use the Seller’s website or the Products, or any information
provided on the website, or in the Products;
b) any claim attributable to errors, omissions or other
inaccuracies in the Product or interpretations thereof.
4.4 All the information contained in the Products has been
obtained from sources believed to be reliable. The Seller
does not warrant the accuracy, completeness adequacy or
reliability of such information, which cannot be guaranteed to
be free from errors.
4.5 All the Products that the Seller sells may, upon prior notice
to the Buyer from time to time be modified by or substituted
with similar Products meeting the needs of the Buyer. This
modification shall not lead to the liability of the Seller,
provided that the Seller ensures the substituted Product is
similar to the Product initially ordered.
4.6 In the case where, after inspection, it is acknowledged that
the Products contain defects, the Seller undertakes to replace
the defective products as far as the supplies allow and without
indemnities or compensation of any kind for labor costs,
delays, loss caused or any other reason. The replacement is
guaranteed for a maximum of two months starting from the
delivery date. Any replacement is excluded for any event as set
out in article 5 below.
4.7 The deadlines that the Seller is asked to state for the mailing
of the Products are given for information only and are not
guaranteed. If such deadlines are not met, it shall not lead to
any damages or cancellation of the orders, except for non
acceptable delays exceeding [4] months from the stated
deadline, without information from the Seller. In such case only,
the Buyer shall be entitled to ask for a reimbursement of its first
down payment to the exclusion of any further damages.
4.8 The Seller does not make any warranties, express or implied,
including, without limitation, those of sale ability and fitness for
a particular purpose, with respect to the Products. Although
the Seller shall take reasonable steps to screen Products for
infection of viruses, worms, Trojan horses or other codes
containing contaminating or destructive properties before
making the Products available, the Seller cannot guarantee
that any Product will be free from infection.
5. FORCE MAJEURE
The Seller shall not be liable for any delay in performance directly
or indirectly caused by or resulting from acts of nature, fire, flood,
accident, riot, war, government intervention, embargoes, strikes,
labor difficulties, equipment failure, late deliveries by suppliers or
other difficulties which are beyond the control, and not the fault
of the Seller.
6. PROTECTION OF THE SELLER’S IPR
6.1 All the IPR attached to the Products are and remain the
property of the Seller and are protected under French and
international copyright law and conventions.
6.2 The Buyer agreed not to disclose, copy, reproduce,
redistribute, resell or publish the Product, or any part of it
to any other party other than employees of its company. The
Buyer shall have the right to use the Products solely for its
own internal information purposes. In particular, the Buyer
shall therefore not use the Product for purposes such as:
• Information storage and retrieval systems;
• Recordings and re-transmittals over any network (including
any local area network);
• Use in any timesharing, service bureau, bulletin board or
similar arrangement or public display;
• Posting any Product to any other online service (including
bulletin boards or the Internet);
• Licensing, leasing, selling, offering for sale or assigning the
Product.
6.3 The Buyer shall be solely responsible towards the Seller of
all infringements of this obligation, whether this infringement
comes from its employees or any person to whom the Buyer
has sent the Products and shall personally take care of any
related proceedings, and the Buyer shall bear related financial
consequences in their entirety.
6.4 The Buyer shall define within its company point of contact for
the needs of the contract. This person will be the recipient
of each new report in PDF format. This person shall also be
responsible for respect of the copyrights and will guaranty that
the Products are not disseminated out of the company.
6.5 In the context of annual subscriptions, the person of contact
shall decide who within the Buyer, shall be entitled to access
on line the reports on I-micronews.com. In this respect, the
Seller will give the Buyer a maximum of 10 password, unless
the multiple sites organization of the Buyer requires more
passwords. The Seller reserves the right to check from time
to time the correct use of this password.
6.6 In the case of a multisite, multi license, only the employee
of the buyer can access the report or the employee of the
companies in which the buyer have 100% shares. As a matter
of fact the investor of a company, the joint venture done with
a third party etc..cannot access the report and should pay a
full license price.
7. TERMINATION
7.1 If the Buyer cancels the order in whole or in part or postpones
the date of mailing, the Buyer shall indemnify the Seller for
the entire costs that have been incurred as at the date of
notification by the Buyer of such delay or cancellation. This
may also apply for any other direct or indirect consequential
loss that may be borne by the Seller, following this decision.
7.2 In the event of breach by one Party under these conditions
or the order, the non-breaching Party may send a notification
to the other by recorded delivery letter upon which, after a
period of thirty (30) days without solving the problem, the
non-breaching Party shall be entitled to terminate all the
pending orders, without being liable for any compensation.
8. MISCELLANEOUS
All the provisions of these Terms and Conditions are for the
benefit of the Seller itself, but also for its licensors, employees
and agents. Each of them is entitled to assert and enforce those
provisions against the Buyer.
Any notices under these Terms and Conditions shall be given in
writing. They shall be effective upon receipt by the other Party.
The Seller may, from time to time, update these Terms and
Conditions and the Buyer, is deemed to have accepted the latest
version of these terms and conditions, provided they have been
communicated to him in due time.
9. GOVERNING LAW AND JURISDICTION
9.1 Any dispute arising out or linked to these Terms and
Conditions or to any contract (orders) entered into in
application of these Terms and Conditions shall be settled
by the French Commercial Courts of Lyon, which shall have
exclusive jurisdiction upon such issues.
9.2 French law shall govern the relation between the Buyer and
the Seller, in accordance with these Terms and Conditions.
TERMS AND CONDITIONS OF SALES 
© 2018
Yole Développement
FromTechnologies to Market
Source: Wikimedia Commons
2©2018 | www.yole.fr | About Yole Développement
FIELDS OF EXPERTISE COVERED BY OUR 40+ ANALYSTS
MEMS  Sensors
Solid State Lighting
(LED, OLED, …)
Compound Semi.
Imaging
Photonics
MedTech
Manufacturing
Advanced
Packaging
Batteries / Energy Management
Power Electronics
Displays
RF
Devices 
Techno.
Advanced
Substrates
Software
3©2018 | www.yole.fr | About Yole Développement
3 BUSINESS MODELS
o Consulting and Analysis
• Market data  research,
marketing analysis
• Technology analysis
• Strategy consulting
• Reverse engineering  costing
• Patent analysis
• Design and characterization of
innovative optical systems
• Financial services (due diligence,
MA with our partner)
www.yole.fr
o Syndicated reports
• Market  technology reports
• Patent investigation and patent
infringement risk analysis
• Teardowns  reverse costing
analysis
• Cost simulation tool
www.i-Micronews.com/reports
o Media
• i-Micronews.com website
• @Micronews e-newsletter
• Communication  webcast
services
• Events:TechDays, forums,…
www.i-Micronews.com
4©2018 | www.yole.fr | About Yole Développement
6 COMPANIES TO SERVEYOUR BUSINESS
Due diligence
www.yole.fr
Manufacturing costs analysis
Teardown and reverse engineering
Cost simulation tools
www.systemplus.fr
Market, technology and strategy
consulting
www.yole.fr
IP analysis
Patent assessment
www.knowmade.fr
Innovation and business maker
www.bmorpho.com
Design and characterization of
innovative optical systems
www.piseo.fr
Yole Group of Companies
5©2018 | www.yole.fr | About Yole Développement
OUR GLOBAL ACTIVITY
30%of our business
40%of our business
30%of our business
Greater
China office
Yole Japan
HQ in Lyon
Nantes
Paris
Nice
Vénissieux
Europe office
Frankfurt
Hsinchu
Tokyo
Yole Inc.
Phoenix
Yole Korea
Seoul
Palo Alto
6©2018 | www.yole.fr | About Yole Développement
ANALYSIS SERVICES - CONTENT COMPARISON
Technology
and Market
Report
Leadership
Meeting
QA
Service
Depth of the analysis
Breadthoftheanalysis
Meet the
Analyst
Custom
Analysis
High
High
Low
7©2018 | www.yole.fr | About Yole Développement
SERVING THE ENTIRE SUPPLY CHAIN
Our analysts
provide
market
analysis,
technology
evaluation,
and business
plans along
the entire
supply chain
Integrators, end-
users and software
developpers
Device manufacturers
Suppliers: material, equipment,
OSAT, foundries…
Financial investors, RD centers
8©2018 | www.yole.fr | About Yole Développement
SERVING MULTIPLE INDUSTRIAL FIELDS
We work
across
multiples
industries to
understand
the impact of
More-than-
Moore
technologies
from device
to system
From A to Z…
Transportation
makers
Mobile phone
and
consumer
electronics
Automotive
Medical
systems
Industrial
and defense
Energy
management
9©2018 | www.yole.fr | About Yole Développement
o Yole Développement, System Plus Consulting, KnowMade and PISEO, all part of Yole Group of Companies, keep on increasing their collaboration to offer, in 2018, a
collection of 150+ reports. Combining respective expertise and methodologies from the 4 companies, the reports aim to provide market  technology analysis, patent
investigation and patent infringement risk analysis, teardowns  reverse costing analysis.They cover:
o You are looking for:
• An analysis of your product market
• A review of your competitors evolution
• An understanding of your manufacturing and production costs
• An understanding of your industry technology roadmap and related IPs
• A clear view on the evolution of the supply chain…
Our reports are for you!
The combined team of 60+ experts (PhDs, MBAs, industry veterans…) from Yole Développement, System Plus Consulting, KnowMade and PISEO, collect information,
identify the trends, the challenges, the emerging markets, the competitive environments and turn it into results to give you a complete picture of your industry
landscape.
In the past 20 years, we worked on more than 1 700 projects, interacting with technology professionals and high level opinion makers from the main players of the
industry.
o In 2018, Yole Group of Companies plan to publish +150 reports. Gain full benefit from our Annual Subscription offers and receive at least a 36% discount.
REPORTS COLLECTION
www.i-Micronews.com
• MEMS  Sensors
• RF devices  technologies
• Imaging
• Medical technologies (MedTech)
• Photonics
• Advanced packaging
• Manufacturing
• Advanced substrates
• Power electronics
• Batteries and energy management
• Compound semiconductors
• Solid state lighting
• Displays
• Software
10©2018 | www.yole.fr | About Yole Développement
OUR 2018 REPORTS COLLECTION (1/3)
MEMS  SENSORS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of the MEMS Industry 2018 - Update
− Silicon Photonics 2018 - Update
− Consumer Biometrics: Sensors  Software 2018 - Update
− MEMS Pressure Sensors 2018
− Air Quality Sensors 2018
− Sensors for AR/VR 2018
o REVERSE ENGINEERING  COSTING REVIEW – by System Plus Consulting
− Gas  Particles Sensors
− MEMS Pressure Sensors
− Piezo MEMS 2018 *
o PATENT ANALYSES – by KnowMade
− MEMS Microphone – Patent Landscape Analysis
RF DEVICES ANDTECHNOLOGIES
o MARKET AND TECHNOLOGY REPORT – byYole Développement
− RF Front End Module and Connectivity for Cellphones 2018 – Update
− 5G Impact on RF Industry: From Wireless Infrastructure to Cellphone Terminals
2018 - Update
− RF GaN 2018 – Update
− Advanced RF System-in-Package for Cellphones 2018 – Update *
− Radar Technologies for Emerging Applications 2018 *
− Radar Technologies for Automotive 2018
− RF  Photonic Technologies for 5G Infrastructure 2018
o REVERSE ENGINEERING  COSTING REVIEW – by System Plus Consulting
− RF Front-End Modules in Smartphones
− RF GaN *
o PATENT ANALYSES – by KnowMade
− RF Front End Module – Patent Landscape Analysis
− RF GaN – Patent Landscape Analysis
IMAGING  OPTOELECTRONICS
o MARKET AND TECHNOLOGY REPORT – byYole Développement
− Status of the CMOS Image Sensor Industry 2018 – Update
− Status of the Compact Camera Module Industry 2018 - Update
− 3D Imaging and Sensing 2018 - Update
− Imaging for Industry and Automation 2018
− Sensors for Robotic Vehicles 2018
− Imagers and Detectors for Security and Smart Buildings 2018
− LiDARs 2018
o QUARTERLY UPDATE – by Yole Développement
− CMOS Image Sensors 2018 *
o REVERSE ENGINEERING  COSTING REVIEW – by System Plus Consulting
− CMOS Image Sensors
− Compact Camera Modules
o PATENT ANALYSES – by KnowMade
− LiDAR – Patent Landscape Analysis
− Time-of-Flight IR Sensor in the Apple iPhone 7 Plus - Patent-to-Product Mapping
SOFTWARE
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Consumer Biometrics: Sensors  Software 2018 - Update
− Processing Hardware and Software for AI: Integration Challenges 2018
Update : 2017 version still available / *To be confirmed
11©2018 | www.yole.fr | About Yole Développement
OUR 2018 REPORTS COLLECTION (2/3)
ADVANCED PACKAGING
o MARKET AND TECHNOLOGY REPORT – byYole Développement
− Status of Advanced Packaging Industry 2018 - Update
− Status of Advanced Substrates 2018: Embedded Die and Interconnects, Substrates
Like PCB Trends
− Fan-Out Packaging 2018 – Update
− 3D TSV and Monolithic Business Update 2018 – Update
− Advanced RF System-in-Package for Cellphones 2018 – Update *
− Power Packaging Modules 2018 - Update
− Discrete Power Packaging 2018 – Update
− MEMS Packaging and Testing 2018 – Update
− Memory Packaging Market and Technology Report 2018 – Update
− Status of Panel Level Packaging 2018
− Trends in Automotive for Advanced Packaging 2018
− Processing Hardware and Software for AI: Integration Challenges 2018
− Integrated Passive Devices (IPD) 2018
o REVERSE ENGINEERING  COSTING REVIEW – by System Plus Consulting
− RF Front-End SiP
− Fan-Out Packaging *
o PATENT ANALYSES – by KnowMade
− Hybrid Bonding for 3D Stack – Patent Landscape Analysis
MANUFACTURING
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Manufacturing Wafer Starts for More than Moore 2018
− Equipment for More than Moore: Technology  Market Trends for Lithography 
Bonding/Debonding 2018
− Equipment for More than Moore: Technology  Market Trends for Thin Film
Deposition  Etching 2018
o REVERSE ENGINEERING  COSTING REVIEW – by System Plus Consulting
− Wafer Bonding Technology Overview 2018
MEMORY
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Emerging Non Volatile Memory 2018 – Update
− Memory Packaging Market and Technology Report 2018 – Update
o QUARTERLY UPDATE – by Yole Développement
− Memory Market 2018 (NAND  DRAM)
o MONTHLY UPDATE – by Yole Développement
− Memory Pricing 2018 (NAND  DRAM)
o REVERSE ENGINEERING  COSTING REVIEW – by System Plus Consulting
− DRAM Technology  Cost Review 2018
− NAND Memory Technology  Cost Review 2018
COMPOUND SEMICONDUCTORS
MARKET AND TECHNOLOGY REPORT – byYole Développement
− Status of Compound Semiconductor Industry 2018 *
− Power SiC 2018: Materials, Devices, and Applications - Update
− Power GaN 2018: Materials, Devices, and Applications – Update
− RF GaN 2018 – Update
− GaAs Materials, Devices and Applications 2018
− InP Materials, Devices and Applications 2018
o REVERSE ENGINEERING  COSTING REVIEW – by System Plus Consulting
− Power SiC Devices
− Power GaN Devices
o PATENT ANALYSES – by KnowMade
− Power SiC – Patent Landscape Analysis
− Status of the GaN IP – Patent Landscape Analysis
Update : 2017 version still available / *To be confirmed
12©2018 | www.yole.fr | About Yole Développement
OUR 2018 REPORTS COLLECTION (3/3)
POWER ELECTRONICS
MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of Power Electronics Industry 2018 - Update
− Power Packaging Modules 2018 - Update
− Discrete Power Packaging 2018 - Update
− EV/HEV Market Expectations and Technology Trends - Update
− Wireless Charging Market Expectations and Technology Trends 2018
− Integrated Passive Devices (IPD) 2018
o QUARTERLY UPDATE – by Yole Développement
− Power ICs Market 2018 – Update
o REVERSE ENGINEERING  COSTING REVIEW – by System Plus Consulting
− Power ICs Market 2018 *
− Power Modules *
BATTERY AND ENERGY MANAGEMENT
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of Battery Industry Update with Focus on Manufacturing 2018 *
− Battery Pack Technology and Business Opportunities 2018 - Update
o PATENT ANALYSES – by KnowMade
− Solid-State Batteries – Patent Landscape Analysis
SOLID STATE LIGHTING
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− IR LEDs and Lasers 2018 - Update
− Automotive Lighting 2018 – Update
− UV LEDs 2018 - Update
− VCSELs 2018
− Lasers 2018
− Light Shaping Technologies 2018
− LiFi 2018
o REVERSE ENGINEERING  COSTING REVIEW – by System Plus Consulting
− VCSELs 2018
− UV LEDs 2018 *
DISPLAYS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− MicroLED Displays 2018 – Update
− Quantum Dots and Wide Color Gamut Display Technologies 2018 - Update
− Organic Thin Film Transistor 2018: Flexible Displays and Other Applications -
Update *
− Displays for AR / VR / MR 2018
− Non Display Applications of MicroLEDs 2018 *
o PATENT ANALYSES – by KnowMade
− MicroLED Display – Patent Landscape Analysis
MEDTECH
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of the BioMEMS Industry 2018 - Update
− Point-of-Need Testing: Application of Microfluidic Technologies 2018 - Update
− Neuro-Technologies for Healthcare and Consumer Applications 2018
− CRISPR Technology: From Lab to Industries 2018
− Portable Medical Imaging 2018
− Inkjet for Additive Manufacturing in the Micro-Electronics Industry 2018
− Liquid Biopsy 2018: From Isolation to Downstream Applications
− Chinese Microfluidics Industry 2018
o PATENT ANALYSES – by KnowMade
− Microfluidic IC Cooling – Patent Landscape Analysis
− Circulating Tumor Cell Isolation – Patent Landscape Analysis
− Organ-on-a-Chip – Patent Landscape Analysis
Update : 2017 version still available / *To be confirmed
13©2018 | www.yole.fr | About Yole Développement
OUR 2017 PUBLISHED REPORTS (1/3)
MEMS  SENSORS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of the MEMS Industry 2017
− High End Inertial Systems Market and Technology 2017
− Magnetic Sensors Market and Technologies 2017
− MEMS and Sensors for Automotive - Market and Technology Trends 2017
− Acoustic MEMS and Audio Solutions 2017
− Sensors and Sensing Modules for Smart Homes and Buildings 2017
− Fingerprint Sensor Applications and Technologies – Consumer Market Focus 2017
o REVERSE COSTING REPORT – by System Plus Consulting
− Continental SRL1: State-of-the-art LiDAR for Advanced Driver Assistance Systems –
Reverse Costing Report
− Bosch Mobility Ultrasonic Sensor – Reverse Costing Report
− MEMS Packaging 2017 - Reverse Costing Review
− Bosch BMP380 Pressure Sensor – Reverse Costing Report
IMAGING  PHOTONICS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of the CMOS Image Sensor Industry 2017
− 3D Imaging and Sensing 2017
− Uncooled Infrared Imaging Technology  Market Trends 2017
− Camera Module Industry Market and Technology Trends 2017
o REVERSE COSTING REPORT – by System Plus Consulting
− FLIR Boson – a small, innovative, low power, smart thermal camera core – Reverse
Costing Report
− Camera Module Physical Analyses Overview 2017
RF DEVICES ANDTECHNOLOGIES
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− RF Front End Modules and Components for Cellphones 2017
− Advanced RF System-in-Package for Cell Phones 2017
− 5G Impact on RF Front-End Industry 2017
ADVANCED PACKAGING
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of the Advanced Packaging Industry 2017
− Embedded Die Packaging: Technology and Market Trends 2017
− Fan-Out: Technologies and Market trends 2017
− Advanced Substrates Overview: From IC Package to Board 2017
− 3D TSV and 2.5D Business Update - Market and Technology Trends 2017
− Advanced RF System-in-Package for Cellphones 2017
− Memory Packaging Market and Technology Report 2017
− MEMS Packaging 2017
− Emerging Non-Volatile Memory 2017
o REVERSE COSTING REPORT – by System Plus Consulting
− NVIDIA Tesla P100 - Reverse Costing Report
− MEMS Packaging - Reverse Technology Review
− Advanced RF SiP for Cellphones 2017 - Reverse Costing Review
SOFTWARE
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Embedded Software in Vision Systems
MEDTECH
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of the Microfluidics Industry 2017
− Solid-State Medical Imaging 2017
− Organs-On-Chips 2017
− Connected Medical Devices Market and Business Models 2017
− Artificial Organ Technology and Market analysis 2017
− Medical Robotics Technology  Market Analysis 2017
14©2018 | www.yole.fr | About Yole Développement
OUR 2017 PUBLISHED REPORTS (2/3)
MANUFACTURING
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Laser Technologies for Semiconductor Manufacturing 2017
− Equipment and Materials for 3D TSV Applications 2017
− Equipment and Materials for Fan-Out Packaging 2017
− Glass Substrate Manufacturing in the Semiconductor Field 2017
BATTERIES  ENERGY MANAGEMENT
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of the Rechargeable Li-ion Battery Industry
− Market Opportunities for Thermal Management Components in Smartphones
DISPLAYS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− MicroLED Displays
− Quantum Dots and Wide Color Gamut Display Technologies
− Phosphors  Quantum Dots 2017 - LED Downconverters for Lighting  Displays
SOLID STATE LIGHTING
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− LED Packaging 2017: Market, Technology and Industry Landscape
− CSP LED Lighting Modules
− IR LEDS and VCSELs - Technology, Applications and Industry Trends
− LED Lighting Module Technology, Industry and Market Trends 2017
− Automotive Lighting: Technology, Industry and Market Trends 2017
− Horticultural LED Lighting: Market, Industry, and Technology Trends
POWER ELECTRONICS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of the Power Electronics Industry 2017
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LEDs 2017
− Gate Driver Market and Technology Trends 2017
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o QUARTERLY UPDATE – by Yole Développement
− Power Management ICs Market 2017
o REVERSE COSTING REPORT – by System Plus Consulting
− EPC2045 100V GaN-on-Silicon Transistor – Reverse Costing Report
− Silicon Capacitor - Technology and Cost Review
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− InvenSense ICM-20789: High Performance 6-Axis Motion Sensor and Pressure Sensor
Combo – Reverse Costing Report
COMPOUND SEMICONDUCTORS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Bulk GaN Substrate Market 2017
− RF Power Market and Technologies 2017: GaN, GaAs and LDMOS
− Power SiC 2017: Materials, Devices, Modules, and Applications
− Power GaN 2017: Epitaxy, Devices, Applications, and Technology Trends
15©2018 | www.yole.fr | About Yole Développement
OUR 2017 PUBLISHED REPORTS LIST (3/3)
OUR PARTNERS’ REPORTS
PATENT ANALYSES – by KnowMade
− Wireless Charging Patent Landscape Analysis
− RF Acoustic Wave Filters Patent Landscape Analysis
− NMC Lithium-Ion Batteries Patent Landscape Analysis
− Pumps for Microfluidic Devices Patent Landscape
− III-N PatentWatch
− FLUIDIGM Patent Portfolio Analysis
− Knowles MEMS Microphones in Apple iPhone 7 Plus Patent-to-Product Mapping 2017
− Consumer Physics SCiO Molecular Sensor Patent-to-Product Mapping
− Patent Licensing Companies in the Semiconductor Market - Patent Litigation Risk and Potential Targets
− MicrofluidicTechnologies for Diagnostic Applications Patent Landscape
TEARDOWN  REVERSE COSTING – by System Plus Consulting
More than 60 teardowns and reverse costing analysis and cost simulation tools published in 2017
MORE INFORMATION
o All the published reports from theYole Group of Companies are available on our website www.i-Micronews.com.
o Ask for our Annual Subscription offers: With our bundle offer, you choose the number of reports you are interested in and select the related offer. You then have up
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automatically (multi-user format). Contact your sales team according to your location (see the last slide).
16©2018 | www.yole.fr | About Yole Développement
MICRONEWS MEDIA
o About Micronews Media
To meet the growing demand for market,
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Micronews Media integrates several tools able
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Unique, cost-effective ways
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are also an efficient way to
adapt with the demands of the
times and to evolve an effective
marketing plan and strategy.
Brand visibility, networking
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Today's technology makes it
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understanding each other is
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for meeting in-person. Events
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increasing your brand/product
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Targeted audience
involvement equals clear,
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Webcasts are a smart,
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Contact: CamilleVeyrier (veyrier@yole.fr), Marketing  Communication Project Manager
17©2018 | www.yole.fr | About Yole Développement
CONTACT INFORMATION
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• North America: Steve LaFerriere, Director of Northern America Business Development
Email: laferriere@yole.fr – +1 31 06 008 267
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Email eloy@yole.fr - +33 4 72 83 01 80
o REPORT BUSINESS
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Email: laferriere@yole.fr – +1 31 06 008 267
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Email: levenez@yole.fr - +49 15 123 544 182
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Email: onozawa@yole.fr - +81 3 4405 9204
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Neurotechnologies and brain computer interface 2018 Report by Yole Developpement

  • 1. From Technologies to Market Sample Neurotechnologies and brain computer interface Market and Technology analysis 2018
  • 2. 2 Abbott,Ad-tech,Advanced Brain Monitoring,AdvaStim,AIST,Aleva Neurotherapeutics,Alphabet,Amazon,Ant Group,ArchiMed, Artinis Medical Systems,Atlas Neuroengineering,ATR, Beijing Pins Medical, BioSemi, Biotronik, Blackrock Microsystems, Boston Scientific, Brain products, BrainCo, Brainscope, Brainsway, Cadwell, Cambridge Neurotech, Caputron, CAS Medical Systems, CEA, Circuit Therapeutics, Cirtec Medical, Compumedics, Cortec, CVTE, Cyberonics, Deep Brain Innovations, Deymed, Dixi Medical, DSM, EaglePicherTechnologies, Electrochem Solutions, electroCore, Elmotiv, Endonovo Therapeutics, EnerSys, Enteromedics, Evergreen MedicalTechnologies, Facebook, Flow, Foc.us, G.Tec, Galvani Bioelectronics, General Electric, Geodesic, Glaxo Smith Klein, Halo Neurosciences, Hamamatsu, Helius Medical,Technologies, Hitachi, iBand+, IBM Watson, IMEC, Integer, Integra, InteraXon, ISS, Jawbone, Kernel, LivaNova, Mag and More, Magstim, Magventure, Mainstay Medical, Med-el Elektromedizinische Geraete, Medtronic, Micro Power Electronics, Micro Systems Technologies, Micromed, Microsoft, MindMaze, Mitsar, MyBrain Technologies, Natus, NEC, Nemos, Nervana, Neurable, Neuralink, NeuroCare, NeuroElectrics, NeuroLutions, NeuroMetrix, Neuronetics, Neuronetics, Neuronexus, Neuropace, Neuros Medical, Neuroscan, NeuroSigma, NeuroSky, Neurosoft, Neurostar, Neurowave, Nevro, Nexeon, Nexstim, Nielsen, Nihon Kohden, Nirox, Nonin Medical, Nuvectra, Olympus, Ornim, Oscor, Pacesetter, Panasonic, Paradromics, Philips, Plexon, PMT Corporation, RetroSense, Rhythm, Ripple, Rythm Dreem, Samsung, SceneRay, Second Sight Medical, Sensomedical, Setpoint Medical, Shimadzu, Siemens, Sony, Sorin Group, Soterix Medical, SPR Therapeutics, Stim Wave,Teijin,Thync,Toyota,Verily,VieLight,Vygon, Ximedica,Ybrain, And many more !! LIST OF COMPANIES MENTIONED IN THIS REPORT ©2018 | www.yole.fr | Neurotechnologies and brain computer interface 240+ slides of market and technology analysis Information gathered through direct discussions with technology developers, end-users and key opinion leaders
  • 3. 3 Biographies & contacts ABOUT THE AUTHORS Jérôme Mouly Dr. Marjorie Villien As a Technology & Market Analyst, Dr. Marjorie Villien is member of the Medical Technologies business unit at Yole Développement (Yole). She is a daily contributor to the development of these activities with a dedicated collection of market & technology reports as well as custom consulting projects. After spending two years at Harvard and prior Yole, Marjorie served as a research scientist at INSERM. Marjorie Villien is graduated from Grenoble INP and holds a PhD in physics & medical imaging. Email: villien@yole.fr Jerôme Mouly serves as a Technology & Market Analyst specialized in microtechnologies for biomedical & medical imaging applications at Yole Développement (Yole). Since 2000, Jérôme has participated in more than 100 marketing and technological analyses for industrial groups, start-ups and institutes related to semiconductor & medical technologies industry. Jérôme holds a Master of Physics from the University of Lyon. Email: mouly@yole.fr KnowMade’s team realized the patent analysis: Dr Coralie Le Greneur Dr Coralie Le Greneur works for Knowmade in the field of Biotechnology and Life Sciences. She holds a PhD in Molecular Biology from the University of Nice Sophia- Antipolis (France). She also holds the International Industrial Studies Diploma in Patents from the CEIPI, Strasbourg (France). Email: coralie.legreneur@knowmade.fr Dr. Brice Sagot Dr. Brice Sagot is COO and cofounder of Knowmade. He is leading the Biotechnology and Life Sciences department. He holds a PhD in molecular biology from the University of Nice Sophia-Antipolis, France. Email: brice.sagot@knowmade.fr
  • 4. 4 OBJECTIVES OF THIS REPORT • Explain the challenges linked to neurotechnologies, and their current/ future applications • Offer a technical and economic segmentation of the neurotechnologies field: neurosensing, neurostimulation, and brain computer interface (BCI) • Deliver an overview of neurotechnologies’ main players and their respective technologies • Furnish market data and forecasts for the period 2017 - 2035, and market dynamics for each segment • Provide neurotechnology roadmaps and an overview of the latest innovations in each segment • Understand the most active companies through a comprehensive patents list for neurostimulation and neurosensing
  • 5. 5 WHO SHOULD BE INTERESTED BY THIS REPORT? o Pharmaceutical and medical device companies: • To understand what is state of the art in neurotechnology • To identify the different players across the supply chain • To get a list of selected players in the field of neurotechnology both in the market and in development • To understand behavior evolution and identify new business models • To identify competitors and targets for collaborations or M&A o Equipment & Material suppliers: • To understand the technical evolution of neurotechnology devices. • To identify business opportunities and prospects o R&D players: • To understand new challenges in neurotechnology o Medical devices outsourcing companies: • To have a broad overview of all neurotechnology applications & markets • To identify new markets • To monitor and benchmark potential competitors • To understand behavior evolution • To identify the key challenges linked to hardware in the field of neurotechnology o Financial & Strategic investors: • To understand the potential for neurotechnology devices in the consumer and healthcare industries • To know the latest trends within the industry • To get a list of players in the field of neurotechnology and their activities
  • 6. 6 TABLE OF CONTENTS • Executive Summary 10 • Introduction 55 • How does the brain work? • Neurological disorders • Brain Initiative • Scope of the report • Segmentation of the Neurotechnology Market 67 • Technological and behavioral/economical criteria • Segmentation • Market Analysis 71 • Mergers and acquisitions • Fundraising analysis • Market data and forecasts 2017-2023 • Neurotechnology ecosystems • IOMT in the neurotechnology business • Roadmaps • Forecasts 2017-2035 using the model of the DNA sequencing history • Neurosensing 90 • Main players and market share • Market data and forecasts 2017 – 2023: system level and electrodes level, by technology and by application • EEG value chain • Main technologies and roadmaps • Patent landscape by KnowMade • Company profiles • Neurostimulation 153 • Main players and market share • Market data and forecasts 2017 – 2023 by technology (DBS, SCS, VNS, TMS, TDCS, etc.) and by application (clinical, research, consumer) • Main technologies and roadmaps • Patent landscape by KnowMade • Company profiles • Brain Computer Interface 204 • Main players • Market data and forecasts 2017 – 2023 by applications • Main technologies and roadmaps • Company profiles • Supply Chain Analysis 227 • General Conclusions 233 • Annex - Patent Landscape Methodology 238
  • 7. 7 INTRODUCTION TO NEUROTECHNOLOGY How does the brain work? (1/2) Most of the technologies aiming at interacting with the brain target the electrical signaling pathway of the neurons • The brain is made of a lot of different types of cells: • Neurons : electrically excitable cells that receive, process, and transmit information through electrical and chemical signals • Microglia : immune system • Oligodendrocytes : provide support and insulation to axons • Astrocytes : variety of tasks, from axon guidance and synaptic support, to the control of the blood brain barrier and blood flow • The axon of the neuron is responsible for conveying an action potential from the cell body to the axon terminus. An action potential is an electrical signal resulting from a sudden, transient change in membrane potential.
  • 8. 8 INTRODUCTION TO NEUROTECHNOLOGY How does the brain work? (2/2) Electrical events propagate the signal within a neuron and chemical processes transmit the signal from one neuron to another • When an action potential reaches an axon terminal it triggers the release of neurotransmitters into the synaptic cleft which diffuses and binds receptors on the postsynaptic neuron. • Sufficient binding will cause the postsynaptic neuron to “fire”. • There are two kinds of neurotransmitters : • Excitatory neurotransmitters stimulate the brain. • Inhibitory neurotransmitters calm the brain and help create balance.
  • 9. 9 INTRODUCTION TO NEUROTECHNOLOGY Neurological disorders Up to 1 billion people, nearly one in six of the world's population, suffer from neurological disorders - 10 20 30 40 50 60 70 80 90 100 Millionspeopleaffected Worldwide prevalence of most neurological disorders (in millions people affected) Trauma Infections Degeneration Psychiatric disorders Tumors Vascular Non- psychiatric disorders 350M 1,140M Source:WHO
  • 10. 10 INTRODUCTION TO NEUROTECHNOLOGY Scope of the report Scope: Neurotechnologies directly interacting with patients Not included in the scope of this report are neurotechnologies based on medical imaging systems not directly interacting with the patient (MRI, MEG, PET, etc.), cochlear implants and retinal prosthesis. Included in this report are neurotechnologies which directly interact with/touch the patient, such as neurosensing technologies (EEG, ECoG, NIRS, etc.), neurostimulation (DBS,VNS,TDCS, etc.) and brain computer interfaces.
  • 11. 11 SEGMENTATION OF THE NEUROTECHNOLOGY MARKET Invasive Non invasive Invasive Non invasive Electrical Light Magnetic Ultrasound Sensing Clinical Electro-corticography, Neural probes Electro- encephalography Near infrared spectroscopy Stimulation Neurostimulation Optogenetics Transcranial magnetic stimulation Focused ultrasounds Transcranial direct current stimulations Near Infrared stimulation Consumer Vagus nerve stimulation Actuation Clinical Brain computer interface Consumer Invasiveness Technology Technological criteriaBehavioral criteria :Technologies not available in clinics yet Segment 2 : Neurostimulation Segment 1 : Neurosensing Segment 3 : Brain Computer Interface Aimofthe system Users
  • 12. 12 NEUROTECHNOLOGY ECOSYSTEM Medical device outsourcing manufacturers Brain computer interface Neurostimulation Neurosensing Electrode manufacturers
  • 13. 13 CONTENT OF THE REPORT Introduction
  • 14. 14 CONTENT OF THE REPORT Market analysis and segmentation
  • 15. 15 CONTENT OF THE REPORT Neurosensing
  • 16. 16 CONTENT OF THE REPORT Neurostimulation
  • 17. 17 CONTENT OF THE REPORT Brain Computer Interface
  • 19. Who has never dreamt of taking control of its environment without using the hands, just thinking? And if these assumptions looking like science fiction are turning to reality thanks to neurotechnologies! For a long time neurosciences were an exclusive domain of healthcare, and technologies associated were serving two main applications: neurostimulation and neurosensing. In early 2000’s the concept of Brain Computer Interface (BCI) emerged with the strong objective to use brain and peripheral nerve information to the benefit of patients. More recently, BCI got the objective not only to serve the medical sector, but to exploit brain signal for a broad range of applications in industrial, military and consumer fields. This has surely caught the attention of ambitious people like Elon Musk who founded Neuralink in this domain in 2017 or Bryan Johnson who invested $100M in his company Kernel. Web giants, with companies such as Google, Facebook and Microsoft are also watching these new technologies carefully. Facebook is strongly involved in project of “typing-by-brain” as a silent- speech interface, while Microsoft is publishing patents on “mind control” that allow users to operate apps using their mind without gesture. Conjunction of neurosciences, advanced micro- technologies and rapid adoption of wearables lead to the emergence of innovative start-up companies and number of initiatives supported by public or private organizations. In the last 3 to 4 years, a wave of fundraising reached a cumulative $300M in BCI companies accompanied by national initiatives like the Obama’s Brain Initiative project supported by US government inspired by the success of the Human Genome Project. If we take the model of the DNA sequencing history, given that researches are going faster today thanks to computer science, it wouldn’t be surprising to see the discovery of a groundbreaking technology to record brain signals before 2030. This report is covering the 3 main segments of neurotechnologies (neurostimulation, neurosensing and BCI), the dynamic of the market through fundraisings, merger & acquisition as well as comprehensive roadmaps of product developments. NEUROTECHNOLOGIES AND BRAIN COMPUTER INTERFACE Market & Technology report - February 2018 WILL NEUROTECHNOLOGIES FOLLOWING THE PATH OF DNA SEQUENCING AND REVOLUTIONIZING NOT ONLY MEDICINE BUT THE ENTIRE SOCIETY? How are neurotechnologies unraveling the mystery of our brain and opening new business opportunities? KEY FEATURES OF THE REPORT Get the sample of the report on www.i-Micronews.com • Introduction to neurotechnologies and market landscapes • Comprehensive market analysis of each segment, covering neurostimulation, neurosensing and brain computer interface • Fundraising analysis, investments and acquisitions • Patent landscape analysis of neurostimulation and neurosensing • Market data and forecasts for 2017 – 2023 with a tentative forecast until 2035, and 2017 market share for each segment • Main technologies and roadmaps • Company profiles with technology descriptions OBJECTIVES OF THE REPORT • Explain the challenges linked to neurotechnologies, and their current and future applications • Offer a technical and economic segmentation of the neurotechnologies field: neurosensing, neurostimulation, brain computer interface • Give an overview of neurotechnologies main players and their respective technologies. • Furnish market data and forecasts for the period 2017-2035, and market dynamics in each segments. • Provide neurotechnology roadmaps and latest innovation in the different segments • Discover the most active companies through comprehensive list of patents in neurostimulation and neurosensing 1980 1990 2000 2010 2020 2030 2040 Final sequencing mapping of the human genome Human genome project ($3B for 15 years international project) Human brain project ($5B for 12 years project) Illumina Next-generation sequencing Third-generation sequencing 100B 1B 10M 100K 1K 10 Speedofsequencing(kbytes/day) Speedofneuronreading (singleneuronsrecorded/seconds) Groundbreaking discovery to record brain signals? (Yole Développement, February 2018) NEUROTECHNOLOGIES: A $4.6B MARKET IN 2017 MAINLY DRIVEN BY THE NEUROSTIMULATION SEGMENT The neurotechnologies market is expected to reach $7.4B in 2023, with a CAGR2017-2023 of 8.3%. Neurostimulation is representing the major part of this market whose key players are giant medical device companies Medtronic, Boston Scientific or Abbott (formerly Saint-Jude Medical) taking most of the market shares. However market shares are slightly moving due to technology improvement Neurotechnologies are following the DNA sequencing history This report includes global trends in patent application identified by KnowMade but does not include an in-depth analysis of any patents.
  • 20. NEUROTECHNOLOGIES AND BRAIN COMPUTER INTERFACE THE MUTATION OF THE NEUROTECHNOLOGY BUSINESS IS GUIDED BY TECHNICAL PROGRESS IN THE SENSING AND STIMULATION DOMAIN AS ATTEST BY THE PATENT LANDSCAPE EVOLUTIONS The rapid development of neurotechnologies is a combination of different factors: technology availability, miniaturization, connectivity, power and rapid adoption of wearables contributes to innovation at sensor and system level. A one shot EEG procedure at hospital and use of wet electrodes is acceptable to the patient. However, development of dry electrodes is bringing more comfort and application for long time monitoring and BCI. As an example, g.tec unveiled its RecoveriX system, an EEG cap with dry active electrodes for training session of patients in rehabilitation. Another trend for brain signal monitoring is the EEG wireless headsets. The CerebAir headset of Nihon Kohden has been developed in close collaboration with IMEC and Holst Center. The platform developed at IMEC is also serving consumer markets for emotion detection. It is worth noting that new electrodes and ergonomic systems give more comfort to users, enabling a broader use of headset in consumer or industrial applications. Companies like Muse and Emotiv are taking benefits of advanced technologies to offer head- bands and headsets that capture user emotions. Other challenges in the neuroscience landscape concerns implanted devices like deep brain stimulators and the battery lifetime, requiring regular surgeries. Boston Scientific has invested to develop a new battery for DBS neurostimulator that more than double current neurostimulator lifetime. in neurostimulation with smaller players bringing new technologies like Neuropace and its closed loop neurostimulator or ElectroCore for the treatment of headache using non-invasive vagus nerve stimulation. But implanted neurostimulators such as spinal cord stimulators for the treatment of pain or deep brain stimulators in the treatment of Parkinson’s disease and epilepsy are still representing a large part of the product sold. Comparatively, neurosensing market for diagnostics and research is a more mature market, and quite conservative when considering Electro- Encephalography (EEG) in clinical applications. Research companies like Brain Products and g.tec are currently very active to develop next generation of electrodes and systems to answer the strong demand for BCI applications. BCI is forecasted to have the strongest growth for the next decades, The report is presenting market data from 2017 to 2035 and the key players on each neurotechnology segment. It presents the fast growing segment of BCI applications, neurostimulation market with detailed stimulating technologies and related players, and neurosensing market focusing on clinical EEG for diagnostics and EEG for research. Market data and forecasts in value 2017-2035 4 2017 2023 2029 2035 $38.4B $13.7B $7.4B $4.6B CAGR2017-2023=8.3% CAGR2023-2029=10.8% CAGR2029-2035=18.8%Neurostimulation Neurosensing BCI Neurosensing roadmap (Yole Développement, February 2018) 3 Gaming, sports Wireless Rehab, sleep monitoring 1920 2000 Today2010 Consumer Consumer/Healthcare research Healthcare Wired EEG – Wet electrodes Dry Electrode based EEG Headset EEG 2020 2030 EEG: Electro-Encephalography (Yole Développement, February 2018)
  • 21. Find more details about this report here: MARKET TECHNOLOGY REPORT COMPANIES CITED IN THE REPORT (non exhaustive list) Abbott, Ad-tech, Advanced Brain Monitoring, AdvaStim, AIST, Aleva Neurotherapeutics, Alphabet, Amazon, Ant Group, ArchiMed, Artinis Medical Systems, Atlas Neuroengineering, ATR, Beijing Pins Medical, BioSemi, Biotronik, Blackrock microsystems, Boston Scientific, Brain products, BrainCo, BrainCo, Brainscope, Brainsway, Cadwell, Cambridge Neurotech, Caputron, CAS Medical Systems, CEA, Circuit therapeutics, Cirtec Medical, Compumedics, Cortec, CVTE, Cyberonics, Deep Brain Innovations, Deymed, Dixi Medical, DSM, EaglePicher Technologies, Electrochem solutions, ElectroCore, Elmotiv, Endonovo therapeutics, EnerSys, Enteromedics, Evergreen medical technologies, Facebook, Flow, Foc.us, g.tec, Galvani bioelectronics, General electric, Geodesic, Glaxo Smith Klein, Halo Neuroscience, Halo Neurosciences, Hamamatsu, Helius Medical, Technologies, Hitachi, iBand+, IBM Watson, IMEC, Integer, Integra, InteraXon, ISS, Jawbone, Kernel, LivaNova, Mag and More, Magstim, Magventure, Mainstay Medical, Med-el elektromedizinische geraete, Medtronic, Micro power electronics, Micro Systems Technologies, Micromed, Microsoft, MindMaze, Mitsar, MyBrain Technologies, Natus, NEC, Nemos, Nervana, Neurable, Neuralink, NeuroCare, NeuroElectrics, NeuroLutions, NeuroMetrix, Neuronetics, Neuronetics, Neuronexus, NeuroPace, Neuropace, Neuros Medical, Neuroscan, NeuroSigma, NeuroSky, Neurosoft, Neurostar, Neurowave, Nevro, Nexeon, Nexstim, Nielsen, Nihon Kohden, Nirox, Nonin Medical, Nuvectra, Olympus, Ornim, Oscor, Pacesetter, Panasonic, Paradromics, Philips, Plexon, PMT corporation, RetroSense, Rhythm, Ripple, Rythm Dreem, Samsung, SceneRay, Second sight medical, Sensomedical, Setpoint Medical, Shimadzu, Siemens, Sony, Sorin Group, Soterix Medical, SPR Therapeutics, Stim Wave, Teijin, Thync, Toyota, Verily, VieLight, Vygon, Ximedica, Ybrain, and many more ! AUTHORS Jerôme Mouly serves as a Technology Market Analyst specialized in microtechnologies for biomedical medical imaging applications at Yole Développement (Yole). Since 2000, Jérôme has participated in more than 100 marketing and technological analyses for industrial groups, start-ups and institutes related to semiconductor medical technologies industry. Jérôme holds a Master of Physics from the University of Lyon. Executive summary 10 Introduction 55 How does the brain work? Neurological disorders Brain initiative Scope of the report Segmentation of the neurotechnologies market 67 Technological and behavioral/economical criteria Segmentation Market analysis 71 Mergers and acquisitions Fundraising analysis Market data and forecasts 2017-2023 Neurotechnologies ecosystem IOMT in the neurotechnology business Roadmaps Forecasts 2017-2035 using the model of the DNA sequencing history Neurosensing 90 Main players and market share Market data and forecasts 2017 – 2023: system level and electrodes level, by technologies and by applications EEG value chain Main technologies and roadmaps Patent landscape Company profiles Neurostimulation 153 Main players and market share Market data and forecasts 2017 – 2023 by technologies (DBS, SCS, VNS, TMS, TDCS, etc.) and by applications (clinical, research, consumer) Main technologies and roadmaps Patent landscape Company profiles Brain computer interface 204 Main players Market data and forecasts 2017 – 2023 by applications Main technologies and roadmaps Company profiles Supply chain analysis 227 General conclusions 233 Annex - Patent landscape methodology 238 TABLE OF CONTENTS (complete content on i-Micronews.com) As a Technology Market Analyst, Dr. Marjorie Villien is member of the Medical Technologies business unit at Yole Développement (Yole). She is a daily contributor to the development of these activities with a dedicated collection of market technology reports as well as custom consulting projects. After spending two years at Harvard and prior Yole, Marjorie served as a research scientist at INSERM. Marjorie Villien is graduated from Grenoble INP and holds a PhD in physics medical imaging. RELATED REPORT Benefit from our Bundle Annual Subscription offers and access our analyses at the best available price and with great advantages • Medical Robotics Technology Market Analysis 2017 • Connected Medical Devices Market and Business Models 2017 • BioMEMS: Microsystems for Healthcare Applications 2016 Find all our reports on www.i-micronews.com Dr Coralie Le Greneur works for Knowmade in the field of Biotechnology and Life Sciences. She holds a PhD in Molecular Biology from the University of Nice Sophia- Antipolis (France). She also holds the International Industrial Studies Diploma in Patents from the CEIPI, Strasbourg (France). This activity in neurosciences is reflected by a huge number of patent publications. Neurosensing accounts for 16,000+ published over a period of 75 years, 25% of whom in the last decade. Players in consumer electronics like Panasonic are holding patent on EEG headset, while players in automotive markets like Toyota are surprisingly holding 10s of patents on EEG systems. Roadmaps of development and availability are available in the report. Technology trends of the report describes how the miniaturization and silicon technologies contributes to manufacturing of invasive probes for local field potential measurement. The report is also describing patent landscape and analysis in both sensing and stimulating devices, highlighting the most active patent assignees and their involvement in the neurotechnology field. Dr. Brice Sagot is COO and co- founder of Knowmade. He is leading the Biotechnology and Life Sciences department. He holds a PhD in molecular biology from the University of Nice Sophia-Antipolis, France. KnowMade’s team realized the patent analysis:
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LIABILITIES 4.1 The Buyer or any other individual or legal person acting on its behalf, being a business user buying the Products for its business activities, shall be solely responsible for choosing the Products and for the use and interpretations he makes of the documents it purchases, of the results he obtains, and of the advice and acts it deduces thereof. 4.2 The Seller shall only be liable for (i) direct and (ii) foreseeable pecuniary loss, caused by the Products or arising from a material breach of this agreement 4.3 In no event shall the Seller be liable for: a) damages of any kind, including without limitation, incidental or consequential damages (including, but not limited to, damages for loss of profits, business interruption and loss of programs or information) arising out of the use of or inability to use the Seller’s website or the Products, or any information provided on the website, or in the Products; b) any claim attributable to errors, omissions or other inaccuracies in the Product or interpretations thereof. 4.4 All the information contained in the Products has been obtained from sources believed to be reliable. The Seller does not warrant the accuracy, completeness adequacy or reliability of such information, which cannot be guaranteed to be free from errors. 4.5 All the Products that the Seller sells may, upon prior notice to the Buyer from time to time be modified by or substituted with similar Products meeting the needs of the Buyer. This modification shall not lead to the liability of the Seller, provided that the Seller ensures the substituted Product is similar to the Product initially ordered. 4.6 In the case where, after inspection, it is acknowledged that the Products contain defects, the Seller undertakes to replace the defective products as far as the supplies allow and without indemnities or compensation of any kind for labor costs, delays, loss caused or any other reason. The replacement is guaranteed for a maximum of two months starting from the delivery date. Any replacement is excluded for any event as set out in article 5 below. 4.7 The deadlines that the Seller is asked to state for the mailing of the Products are given for information only and are not guaranteed. If such deadlines are not met, it shall not lead to any damages or cancellation of the orders, except for non acceptable delays exceeding [4] months from the stated deadline, without information from the Seller. In such case only, the Buyer shall be entitled to ask for a reimbursement of its first down payment to the exclusion of any further damages. 4.8 The Seller does not make any warranties, express or implied, including, without limitation, those of sale ability and fitness for a particular purpose, with respect to the Products. Although the Seller shall take reasonable steps to screen Products for infection of viruses, worms, Trojan horses or other codes containing contaminating or destructive properties before making the Products available, the Seller cannot guarantee that any Product will be free from infection. 5. FORCE MAJEURE The Seller shall not be liable for any delay in performance directly or indirectly caused by or resulting from acts of nature, fire, flood, accident, riot, war, government intervention, embargoes, strikes, labor difficulties, equipment failure, late deliveries by suppliers or other difficulties which are beyond the control, and not the fault of the Seller. 6. PROTECTION OF THE SELLER’S IPR 6.1 All the IPR attached to the Products are and remain the property of the Seller and are protected under French and international copyright law and conventions. 6.2 The Buyer agreed not to disclose, copy, reproduce, redistribute, resell or publish the Product, or any part of it to any other party other than employees of its company. The Buyer shall have the right to use the Products solely for its own internal information purposes. In particular, the Buyer shall therefore not use the Product for purposes such as: • Information storage and retrieval systems; • Recordings and re-transmittals over any network (including any local area network); • Use in any timesharing, service bureau, bulletin board or similar arrangement or public display; • Posting any Product to any other online service (including bulletin boards or the Internet); • Licensing, leasing, selling, offering for sale or assigning the Product. 6.3 The Buyer shall be solely responsible towards the Seller of all infringements of this obligation, whether this infringement comes from its employees or any person to whom the Buyer has sent the Products and shall personally take care of any related proceedings, and the Buyer shall bear related financial consequences in their entirety. 6.4 The Buyer shall define within its company point of contact for the needs of the contract. This person will be the recipient of each new report in PDF format. This person shall also be responsible for respect of the copyrights and will guaranty that the Products are not disseminated out of the company. 6.5 In the context of annual subscriptions, the person of contact shall decide who within the Buyer, shall be entitled to access on line the reports on I-micronews.com. In this respect, the Seller will give the Buyer a maximum of 10 password, unless the multiple sites organization of the Buyer requires more passwords. The Seller reserves the right to check from time to time the correct use of this password. 6.6 In the case of a multisite, multi license, only the employee of the buyer can access the report or the employee of the companies in which the buyer have 100% shares. As a matter of fact the investor of a company, the joint venture done with a third party etc..cannot access the report and should pay a full license price. 7. TERMINATION 7.1 If the Buyer cancels the order in whole or in part or postpones the date of mailing, the Buyer shall indemnify the Seller for the entire costs that have been incurred as at the date of notification by the Buyer of such delay or cancellation. This may also apply for any other direct or indirect consequential loss that may be borne by the Seller, following this decision. 7.2 In the event of breach by one Party under these conditions or the order, the non-breaching Party may send a notification to the other by recorded delivery letter upon which, after a period of thirty (30) days without solving the problem, the non-breaching Party shall be entitled to terminate all the pending orders, without being liable for any compensation. 8. MISCELLANEOUS All the provisions of these Terms and Conditions are for the benefit of the Seller itself, but also for its licensors, employees and agents. Each of them is entitled to assert and enforce those provisions against the Buyer. Any notices under these Terms and Conditions shall be given in writing. They shall be effective upon receipt by the other Party. The Seller may, from time to time, update these Terms and Conditions and the Buyer, is deemed to have accepted the latest version of these terms and conditions, provided they have been communicated to him in due time. 9. GOVERNING LAW AND JURISDICTION 9.1 Any dispute arising out or linked to these Terms and Conditions or to any contract (orders) entered into in application of these Terms and Conditions shall be settled by the French Commercial Courts of Lyon, which shall have exclusive jurisdiction upon such issues. 9.2 French law shall govern the relation between the Buyer and the Seller, in accordance with these Terms and Conditions. TERMS AND CONDITIONS OF SALES 
  • 24. © 2018 Yole Développement FromTechnologies to Market Source: Wikimedia Commons
  • 25. 2©2018 | www.yole.fr | About Yole Développement FIELDS OF EXPERTISE COVERED BY OUR 40+ ANALYSTS MEMS Sensors Solid State Lighting (LED, OLED, …) Compound Semi. Imaging Photonics MedTech Manufacturing Advanced Packaging Batteries / Energy Management Power Electronics Displays RF Devices Techno. Advanced Substrates Software
  • 26. 3©2018 | www.yole.fr | About Yole Développement 3 BUSINESS MODELS o Consulting and Analysis • Market data research, marketing analysis • Technology analysis • Strategy consulting • Reverse engineering costing • Patent analysis • Design and characterization of innovative optical systems • Financial services (due diligence, MA with our partner) www.yole.fr o Syndicated reports • Market technology reports • Patent investigation and patent infringement risk analysis • Teardowns reverse costing analysis • Cost simulation tool www.i-Micronews.com/reports o Media • i-Micronews.com website • @Micronews e-newsletter • Communication webcast services • Events:TechDays, forums,… www.i-Micronews.com
  • 27. 4©2018 | www.yole.fr | About Yole Développement 6 COMPANIES TO SERVEYOUR BUSINESS Due diligence www.yole.fr Manufacturing costs analysis Teardown and reverse engineering Cost simulation tools www.systemplus.fr Market, technology and strategy consulting www.yole.fr IP analysis Patent assessment www.knowmade.fr Innovation and business maker www.bmorpho.com Design and characterization of innovative optical systems www.piseo.fr Yole Group of Companies
  • 28. 5©2018 | www.yole.fr | About Yole Développement OUR GLOBAL ACTIVITY 30%of our business 40%of our business 30%of our business Greater China office Yole Japan HQ in Lyon Nantes Paris Nice Vénissieux Europe office Frankfurt Hsinchu Tokyo Yole Inc. Phoenix Yole Korea Seoul Palo Alto
  • 29. 6©2018 | www.yole.fr | About Yole Développement ANALYSIS SERVICES - CONTENT COMPARISON Technology and Market Report Leadership Meeting QA Service Depth of the analysis Breadthoftheanalysis Meet the Analyst Custom Analysis High High Low
  • 30. 7©2018 | www.yole.fr | About Yole Développement SERVING THE ENTIRE SUPPLY CHAIN Our analysts provide market analysis, technology evaluation, and business plans along the entire supply chain Integrators, end- users and software developpers Device manufacturers Suppliers: material, equipment, OSAT, foundries… Financial investors, RD centers
  • 31. 8©2018 | www.yole.fr | About Yole Développement SERVING MULTIPLE INDUSTRIAL FIELDS We work across multiples industries to understand the impact of More-than- Moore technologies from device to system From A to Z… Transportation makers Mobile phone and consumer electronics Automotive Medical systems Industrial and defense Energy management
  • 32. 9©2018 | www.yole.fr | About Yole Développement o Yole Développement, System Plus Consulting, KnowMade and PISEO, all part of Yole Group of Companies, keep on increasing their collaboration to offer, in 2018, a collection of 150+ reports. Combining respective expertise and methodologies from the 4 companies, the reports aim to provide market technology analysis, patent investigation and patent infringement risk analysis, teardowns reverse costing analysis.They cover: o You are looking for: • An analysis of your product market • A review of your competitors evolution • An understanding of your manufacturing and production costs • An understanding of your industry technology roadmap and related IPs • A clear view on the evolution of the supply chain… Our reports are for you! The combined team of 60+ experts (PhDs, MBAs, industry veterans…) from Yole Développement, System Plus Consulting, KnowMade and PISEO, collect information, identify the trends, the challenges, the emerging markets, the competitive environments and turn it into results to give you a complete picture of your industry landscape. In the past 20 years, we worked on more than 1 700 projects, interacting with technology professionals and high level opinion makers from the main players of the industry. o In 2018, Yole Group of Companies plan to publish +150 reports. Gain full benefit from our Annual Subscription offers and receive at least a 36% discount. REPORTS COLLECTION www.i-Micronews.com • MEMS Sensors • RF devices technologies • Imaging • Medical technologies (MedTech) • Photonics • Advanced packaging • Manufacturing • Advanced substrates • Power electronics • Batteries and energy management • Compound semiconductors • Solid state lighting • Displays • Software
  • 33. 10©2018 | www.yole.fr | About Yole Développement OUR 2018 REPORTS COLLECTION (1/3) MEMS SENSORS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of the MEMS Industry 2018 - Update − Silicon Photonics 2018 - Update − Consumer Biometrics: Sensors Software 2018 - Update − MEMS Pressure Sensors 2018 − Air Quality Sensors 2018 − Sensors for AR/VR 2018 o REVERSE ENGINEERING COSTING REVIEW – by System Plus Consulting − Gas Particles Sensors − MEMS Pressure Sensors − Piezo MEMS 2018 * o PATENT ANALYSES – by KnowMade − MEMS Microphone – Patent Landscape Analysis RF DEVICES ANDTECHNOLOGIES o MARKET AND TECHNOLOGY REPORT – byYole Développement − RF Front End Module and Connectivity for Cellphones 2018 – Update − 5G Impact on RF Industry: From Wireless Infrastructure to Cellphone Terminals 2018 - Update − RF GaN 2018 – Update − Advanced RF System-in-Package for Cellphones 2018 – Update * − Radar Technologies for Emerging Applications 2018 * − Radar Technologies for Automotive 2018 − RF Photonic Technologies for 5G Infrastructure 2018 o REVERSE ENGINEERING COSTING REVIEW – by System Plus Consulting − RF Front-End Modules in Smartphones − RF GaN * o PATENT ANALYSES – by KnowMade − RF Front End Module – Patent Landscape Analysis − RF GaN – Patent Landscape Analysis IMAGING OPTOELECTRONICS o MARKET AND TECHNOLOGY REPORT – byYole Développement − Status of the CMOS Image Sensor Industry 2018 – Update − Status of the Compact Camera Module Industry 2018 - Update − 3D Imaging and Sensing 2018 - Update − Imaging for Industry and Automation 2018 − Sensors for Robotic Vehicles 2018 − Imagers and Detectors for Security and Smart Buildings 2018 − LiDARs 2018 o QUARTERLY UPDATE – by Yole Développement − CMOS Image Sensors 2018 * o REVERSE ENGINEERING COSTING REVIEW – by System Plus Consulting − CMOS Image Sensors − Compact Camera Modules o PATENT ANALYSES – by KnowMade − LiDAR – Patent Landscape Analysis − Time-of-Flight IR Sensor in the Apple iPhone 7 Plus - Patent-to-Product Mapping SOFTWARE o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Consumer Biometrics: Sensors Software 2018 - Update − Processing Hardware and Software for AI: Integration Challenges 2018 Update : 2017 version still available / *To be confirmed
  • 34. 11©2018 | www.yole.fr | About Yole Développement OUR 2018 REPORTS COLLECTION (2/3) ADVANCED PACKAGING o MARKET AND TECHNOLOGY REPORT – byYole Développement − Status of Advanced Packaging Industry 2018 - Update − Status of Advanced Substrates 2018: Embedded Die and Interconnects, Substrates Like PCB Trends − Fan-Out Packaging 2018 – Update − 3D TSV and Monolithic Business Update 2018 – Update − Advanced RF System-in-Package for Cellphones 2018 – Update * − Power Packaging Modules 2018 - Update − Discrete Power Packaging 2018 – Update − MEMS Packaging and Testing 2018 – Update − Memory Packaging Market and Technology Report 2018 – Update − Status of Panel Level Packaging 2018 − Trends in Automotive for Advanced Packaging 2018 − Processing Hardware and Software for AI: Integration Challenges 2018 − Integrated Passive Devices (IPD) 2018 o REVERSE ENGINEERING COSTING REVIEW – by System Plus Consulting − RF Front-End SiP − Fan-Out Packaging * o PATENT ANALYSES – by KnowMade − Hybrid Bonding for 3D Stack – Patent Landscape Analysis MANUFACTURING o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Manufacturing Wafer Starts for More than Moore 2018 − Equipment for More than Moore: Technology Market Trends for Lithography Bonding/Debonding 2018 − Equipment for More than Moore: Technology Market Trends for Thin Film Deposition Etching 2018 o REVERSE ENGINEERING COSTING REVIEW – by System Plus Consulting − Wafer Bonding Technology Overview 2018 MEMORY o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Emerging Non Volatile Memory 2018 – Update − Memory Packaging Market and Technology Report 2018 – Update o QUARTERLY UPDATE – by Yole Développement − Memory Market 2018 (NAND DRAM) o MONTHLY UPDATE – by Yole Développement − Memory Pricing 2018 (NAND DRAM) o REVERSE ENGINEERING COSTING REVIEW – by System Plus Consulting − DRAM Technology Cost Review 2018 − NAND Memory Technology Cost Review 2018 COMPOUND SEMICONDUCTORS MARKET AND TECHNOLOGY REPORT – byYole Développement − Status of Compound Semiconductor Industry 2018 * − Power SiC 2018: Materials, Devices, and Applications - Update − Power GaN 2018: Materials, Devices, and Applications – Update − RF GaN 2018 – Update − GaAs Materials, Devices and Applications 2018 − InP Materials, Devices and Applications 2018 o REVERSE ENGINEERING COSTING REVIEW – by System Plus Consulting − Power SiC Devices − Power GaN Devices o PATENT ANALYSES – by KnowMade − Power SiC – Patent Landscape Analysis − Status of the GaN IP – Patent Landscape Analysis Update : 2017 version still available / *To be confirmed
  • 35. 12©2018 | www.yole.fr | About Yole Développement OUR 2018 REPORTS COLLECTION (3/3) POWER ELECTRONICS MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of Power Electronics Industry 2018 - Update − Power Packaging Modules 2018 - Update − Discrete Power Packaging 2018 - Update − EV/HEV Market Expectations and Technology Trends - Update − Wireless Charging Market Expectations and Technology Trends 2018 − Integrated Passive Devices (IPD) 2018 o QUARTERLY UPDATE – by Yole Développement − Power ICs Market 2018 – Update o REVERSE ENGINEERING COSTING REVIEW – by System Plus Consulting − Power ICs Market 2018 * − Power Modules * BATTERY AND ENERGY MANAGEMENT o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of Battery Industry Update with Focus on Manufacturing 2018 * − Battery Pack Technology and Business Opportunities 2018 - Update o PATENT ANALYSES – by KnowMade − Solid-State Batteries – Patent Landscape Analysis SOLID STATE LIGHTING o MARKET AND TECHNOLOGY REPORT – by Yole Développement − IR LEDs and Lasers 2018 - Update − Automotive Lighting 2018 – Update − UV LEDs 2018 - Update − VCSELs 2018 − Lasers 2018 − Light Shaping Technologies 2018 − LiFi 2018 o REVERSE ENGINEERING COSTING REVIEW – by System Plus Consulting − VCSELs 2018 − UV LEDs 2018 * DISPLAYS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − MicroLED Displays 2018 – Update − Quantum Dots and Wide Color Gamut Display Technologies 2018 - Update − Organic Thin Film Transistor 2018: Flexible Displays and Other Applications - Update * − Displays for AR / VR / MR 2018 − Non Display Applications of MicroLEDs 2018 * o PATENT ANALYSES – by KnowMade − MicroLED Display – Patent Landscape Analysis MEDTECH o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of the BioMEMS Industry 2018 - Update − Point-of-Need Testing: Application of Microfluidic Technologies 2018 - Update − Neuro-Technologies for Healthcare and Consumer Applications 2018 − CRISPR Technology: From Lab to Industries 2018 − Portable Medical Imaging 2018 − Inkjet for Additive Manufacturing in the Micro-Electronics Industry 2018 − Liquid Biopsy 2018: From Isolation to Downstream Applications − Chinese Microfluidics Industry 2018 o PATENT ANALYSES – by KnowMade − Microfluidic IC Cooling – Patent Landscape Analysis − Circulating Tumor Cell Isolation – Patent Landscape Analysis − Organ-on-a-Chip – Patent Landscape Analysis Update : 2017 version still available / *To be confirmed
  • 36. 13©2018 | www.yole.fr | About Yole Développement OUR 2017 PUBLISHED REPORTS (1/3) MEMS SENSORS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of the MEMS Industry 2017 − High End Inertial Systems Market and Technology 2017 − Magnetic Sensors Market and Technologies 2017 − MEMS and Sensors for Automotive - Market and Technology Trends 2017 − Acoustic MEMS and Audio Solutions 2017 − Sensors and Sensing Modules for Smart Homes and Buildings 2017 − Fingerprint Sensor Applications and Technologies – Consumer Market Focus 2017 o REVERSE COSTING REPORT – by System Plus Consulting − Continental SRL1: State-of-the-art LiDAR for Advanced Driver Assistance Systems – Reverse Costing Report − Bosch Mobility Ultrasonic Sensor – Reverse Costing Report − MEMS Packaging 2017 - Reverse Costing Review − Bosch BMP380 Pressure Sensor – Reverse Costing Report IMAGING PHOTONICS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of the CMOS Image Sensor Industry 2017 − 3D Imaging and Sensing 2017 − Uncooled Infrared Imaging Technology Market Trends 2017 − Camera Module Industry Market and Technology Trends 2017 o REVERSE COSTING REPORT – by System Plus Consulting − FLIR Boson – a small, innovative, low power, smart thermal camera core – Reverse Costing Report − Camera Module Physical Analyses Overview 2017 RF DEVICES ANDTECHNOLOGIES o MARKET AND TECHNOLOGY REPORT – by Yole Développement − RF Front End Modules and Components for Cellphones 2017 − Advanced RF System-in-Package for Cell Phones 2017 − 5G Impact on RF Front-End Industry 2017 ADVANCED PACKAGING o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of the Advanced Packaging Industry 2017 − Embedded Die Packaging: Technology and Market Trends 2017 − Fan-Out: Technologies and Market trends 2017 − Advanced Substrates Overview: From IC Package to Board 2017 − 3D TSV and 2.5D Business Update - Market and Technology Trends 2017 − Advanced RF System-in-Package for Cellphones 2017 − Memory Packaging Market and Technology Report 2017 − MEMS Packaging 2017 − Emerging Non-Volatile Memory 2017 o REVERSE COSTING REPORT – by System Plus Consulting − NVIDIA Tesla P100 - Reverse Costing Report − MEMS Packaging - Reverse Technology Review − Advanced RF SiP for Cellphones 2017 - Reverse Costing Review SOFTWARE o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Embedded Software in Vision Systems MEDTECH o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of the Microfluidics Industry 2017 − Solid-State Medical Imaging 2017 − Organs-On-Chips 2017 − Connected Medical Devices Market and Business Models 2017 − Artificial Organ Technology and Market analysis 2017 − Medical Robotics Technology Market Analysis 2017
  • 37. 14©2018 | www.yole.fr | About Yole Développement OUR 2017 PUBLISHED REPORTS (2/3) MANUFACTURING o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Laser Technologies for Semiconductor Manufacturing 2017 − Equipment and Materials for 3D TSV Applications 2017 − Equipment and Materials for Fan-Out Packaging 2017 − Glass Substrate Manufacturing in the Semiconductor Field 2017 BATTERIES ENERGY MANAGEMENT o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of the Rechargeable Li-ion Battery Industry − Market Opportunities for Thermal Management Components in Smartphones DISPLAYS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − MicroLED Displays − Quantum Dots and Wide Color Gamut Display Technologies − Phosphors Quantum Dots 2017 - LED Downconverters for Lighting Displays SOLID STATE LIGHTING o MARKET AND TECHNOLOGY REPORT – by Yole Développement − LED Packaging 2017: Market, Technology and Industry Landscape − CSP LED Lighting Modules − IR LEDS and VCSELs - Technology, Applications and Industry Trends − LED Lighting Module Technology, Industry and Market Trends 2017 − Automotive Lighting: Technology, Industry and Market Trends 2017 − Horticultural LED Lighting: Market, Industry, and Technology Trends POWER ELECTRONICS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of the Power Electronics Industry 2017 − Thermal Management Technology and Market Perspectives in Power Electronics and LEDs 2017 − Gate Driver Market and Technology Trends 2017 − Power MOSFET 2017: Market and Technology Trends − Power Module Packaging: Material Market and Technology Trends 2017 − IGBT Market and Technology Trends 2017 o QUARTERLY UPDATE – by Yole Développement − Power Management ICs Market 2017 o REVERSE COSTING REPORT – by System Plus Consulting − EPC2045 100V GaN-on-Silicon Transistor – Reverse Costing Report − Silicon Capacitor - Technology and Cost Review − Industrial 100V MOSFET - Technology and Cost Review − InvenSense ICM-20789: High Performance 6-Axis Motion Sensor and Pressure Sensor Combo – Reverse Costing Report COMPOUND SEMICONDUCTORS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Bulk GaN Substrate Market 2017 − RF Power Market and Technologies 2017: GaN, GaAs and LDMOS − Power SiC 2017: Materials, Devices, Modules, and Applications − Power GaN 2017: Epitaxy, Devices, Applications, and Technology Trends
  • 38. 15©2018 | www.yole.fr | About Yole Développement OUR 2017 PUBLISHED REPORTS LIST (3/3) OUR PARTNERS’ REPORTS PATENT ANALYSES – by KnowMade − Wireless Charging Patent Landscape Analysis − RF Acoustic Wave Filters Patent Landscape Analysis − NMC Lithium-Ion Batteries Patent Landscape Analysis − Pumps for Microfluidic Devices Patent Landscape − III-N PatentWatch − FLUIDIGM Patent Portfolio Analysis − Knowles MEMS Microphones in Apple iPhone 7 Plus Patent-to-Product Mapping 2017 − Consumer Physics SCiO Molecular Sensor Patent-to-Product Mapping − Patent Licensing Companies in the Semiconductor Market - Patent Litigation Risk and Potential Targets − MicrofluidicTechnologies for Diagnostic Applications Patent Landscape TEARDOWN REVERSE COSTING – by System Plus Consulting More than 60 teardowns and reverse costing analysis and cost simulation tools published in 2017 MORE INFORMATION o All the published reports from theYole Group of Companies are available on our website www.i-Micronews.com. o Ask for our Annual Subscription offers: With our bundle offer, you choose the number of reports you are interested in and select the related offer. You then have up to 12 months to select the required reports from the Yole Développement, System Plus Consulting and KnowMade offering. Pay once and receive the reports automatically (multi-user format). Contact your sales team according to your location (see the last slide).
  • 39. 16©2018 | www.yole.fr | About Yole Développement MICRONEWS MEDIA o About Micronews Media To meet the growing demand for market, technological and business information, Micronews Media integrates several tools able to reach each individual contact within its network.We will ensure you benefit from this. ONLINE ONSITE INPERSON @Micronews e-newsletter i-Micronews.com i-Micronewsjp.com FreeFullPDF.com Events Webcasts Unique, cost-effective ways to reach global audiences. Online display advertising campaigns are great strategies for improving your product/brand visibility.They are also an efficient way to adapt with the demands of the times and to evolve an effective marketing plan and strategy. Brand visibility, networking opportunities Today's technology makes it easy for us to communicate regularly, quickly, and inexpensively – but when understanding each other is critical, there is no substitute for meeting in-person. Events are the best way to exchange ideas with your customers, partners, prospects while increasing your brand/product visibility. Targeted audience involvement equals clear, concise perception of your company’s message. Webcasts are a smart, innovative way of communicating to a wider targeted audience.Webcasts create very useful, dynamic reference material for attendees and also for absentees, thanks to the recording technology. Benefit from the i-Micronews.com traffic generated by the 11,200+ monthly unique visitors, the 10,500+ weekly readers of @Micronew se-newsletter Several key events planned for 2018 on different topics to attract 120 attendees on average Gain new leads for your business from an average of 340 registrants per webcast Contact: CamilleVeyrier (veyrier@yole.fr), Marketing Communication Project Manager
  • 40. 17©2018 | www.yole.fr | About Yole Développement CONTACT INFORMATION o CONSULTING AND SPECIFIC ANALYSIS • North America: Steve LaFerriere, Director of Northern America Business Development Email: laferriere@yole.fr – +1 31 06 008 267 • Japan Rest of Asia: Takashi Onozawa, General Manager, Asia Business Development Email: onozawa@yole.fr - +81 3 4405 9204 • Greater China: Mavis Wang, Director of Greater China Business Development Email: wang@yole.fr - +886 979 336 809 • RoW: Jean-Christophe Eloy, CEO President, Yole Développement Email eloy@yole.fr - +33 4 72 83 01 80 o REPORT BUSINESS • North America: Steve LaFerriere, Director of Northern America Business Development Email: laferriere@yole.fr – +1 31 06 008 267 • Europe: Lizzie Levenez, EMEA Business Development Manager Email: levenez@yole.fr - +49 15 123 544 182 • Rest of Asia: Takashi Onozawa, General Manager, Asia Business Development Email: onozawa@yole.fr - +81 3 4405 9204 • Japan: • Miho Othake, Account Manager Email: ohtake@yole.fr - +81 3 4405 9204 • Itsuyo Oshiba, Account Manager Email: oshiba@yole.fr - +81-80-3577-3042 • Greater China: Mavis Wang, Director of Greater China Business Development Email: wang@yole.fr - +886 979 336 809 o FINANCIAL SERVICES (in partnership with Woodside Capital Partners) • Jean-Christophe Eloy, CEO President Email: eloy@yole.fr - +33 4 72 83 01 80 o GENERAL • Public Relations: leroy@yole.fr - +33 4 72 83 01 89 • Email: info@yole.fr - +33 4 72 83 01 80 Follow us on