1. Prozac and Depression Patients RISE Program Proposal By: Zoe C Negron Comas

2. Is Prozac to credit for betterment in depression patients?

3. Objectives Find out whether or not Prozac truly helps and if so how?

4. Depression Feelings of helplessness and hopelessness Loss of interest in daily activities Appetite or weight changes Sleep changes Psychomotor agitation or retardation Loss of energy Self-loathing Concentration problems Types of Depression Major Depression Atypical Depression Dysthimia Seasonal Affective Disorder

5. Anti-depressant Selective Serotonin Reuptake Inhibitors Treatment for: major depressive disorder bulimia nervosa obsessive-compulsive disorder panic disorder premenstrual dysphoric disorder Prozac

6. Found in: Intestines Central Nervous System Neurotransmitter Affects: Mood Appetite Sex drive Sleep Pain Attention Serotonin

7. Serotonin and Depression

8. Prozac and Serotonin

9. Hypothesis: Prozac is renewing neurons and that is what is causing the antidepressant effect, not the inhibition of Serotonin uptake. Prozac and Depression

10. Permits Select Psychologists Evaluate patients with depression Select 20 patients with similar characteristics Level of depression Inciting incidents Choosing Subjects

11. Evaluation State of mind Emotional state fMRI Test neural activity Previous to the Procedure

12. Experimental Group 10 patients with Prozac fMRI and evaluate: One day One week Control Group 10 patients with placebo fMRI and Evaluate One day One week Methodology

13. Find true cause of depression Find alternative treatments Long Term Goals