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11. The physician orders gemcitabine 1,000mg IV now for a patient with ovarian cancer. The
pharmacy sends a 1g vial of powdered Gemcitabine for Injection, USP, with the following
directions for reconstitution: "To reconstitute, add 5mL of 0.98 Sodium Chloride injection to the
200mg vial or 25mL of 0.9% Sodium Chloride Injection to the 1g vial. Shake to dissolve. These
dilutions each yield a gemcitabine concentration of 38 mg/mL To correctly administer the ordered
amount, the nurse will add diluent, shake to dissolve, and withdraw of the reconstituted
gemcitabine into a syringe. Diluent: 5mL; Reconstituted medication: 0.3mL Diluent: 5mL;
Reconstituted medication: 0.4mL Diluent: 25 mL; Reconstituted medication 26.3mL Diluent: 25mL
: Reconstituted medication 28mt.

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