The Notch mutation is located on the X chromosome in Drosophila melanogaster. Females heterozygous for Notch have indented wing margins, while the mutation is lethal in homozygous and hemizygous conditions. The Notch deletion includes the locus for white eyes, an X-linked recessive trait. Crosses between a red-eyed Notch female and a red-eyed male, or between two red-eyed Notch females, result in offspring with a 1:1:1:1 ratio of white-eyed females, white-eyed males, red-eyed Notch females, and red-eyed males.
The Notch mutation is a dolotion on tho Xchromosorne of Dro.pdf
1. The Notch mutation is a dolotion on tho X-chromosorne of Drosophilg melanogastor, Female fies
hetcrozygous for Noroh have an indentation on the margins af thair wings: Notch is lethal in the
homozygous and hemarygous conditions. The Nolch deleton covers the tegion of the X-
chromocome that containg the locus for white eyes. an X-linked recessive trait. Give the
phenotypes and proportions of progeny produced in the following crosses: a red-eyod. Notch
fomalo is matod with a red-eyed male. 1/3 white-oyod. Notch females, 1/3 while-eyod females, 1/3
white-eyed males 1/3 red-eyed, Notch malas, 1/3 red-eyed, Notch females, 1/3 red-eyod temales
233 red-eyed, Notch females, 1/3 white-eyed males is rod-eyed, Notch females, 1/3 red-eyed
females. 18 red-eyed males
