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Pediatric Community Acquired Pneumonia
1. CASE MANAGEMENT
CONFERENCE
Presented by:
Allan Joseph O. Santos
Nurol Iman L. Cabugatan
Amer Hussien P. Samporna
Department of Pediatrics
November 21, 2014
8:00 – 10:00 am
Basilio Valdes Hall
2. IDENTIFYING DATA
• M.D.
• 2 yr & 2 mos old
• Female
• Filipino
• Roman Catholic
• Makati City
• 2nd admission
• October 25, 2014 ( 3:19 pm )
5. HISTORY OF PRESENT ILLNESS
• Fever : intermittent
: high grade
: Tmax : 40o C
• No other symptoms
• Self medicated : Paracetamol (15mkdose)
9 days PTA .
6. HISTORY OF PRESENT ILLNESS
• Consult OLLH-ER : laboratory exam
9 days PTA . .
CBC PC RESULT
Hemoglobin 124
Hematocrit 0.37
WBC
3.9
Segmenters 0.64
Stabs 0.01
Lymphocytes 0.30
Monocytes 0.05
Platelet count 268
URINALYSIS RESULT
Color Yellow
Transparency Slightly Cloudy
Reaction 6.0
Specific gravity 1.015
Glucose Negative
Albumin Negative
Epithelial cells Few
RBC 2-4/hpf
Pus cells 0-1/hpf
Amorphous urates Few
Mucus threads Occasional
Bacteria Occasional
7. HISTORY OF PRESENT ILLNESS
• Consult OLLH-ER : PE : Normal
: Dx : AVI
: Tx : Paracetamol (15mkdose)
: sent home
• Symptoms : resolved
9 days PTA . . .
8. HISTORY OF PRESENT ILLNESS
• Afebrile
• Cough : occasional
: non productive
• No : other signs and symptoms
: consult
• Self medicated : Salbutamol + Bromhexine + Guaifenesin syrup
: Salbutamol + Ipratropium nebule
• Symptom : temporary relief
7 days PTA
9. HISTORY OF PRESENT ILLNESS
• Cough : persisted
: productive
• Fever : recurrent
: intermittent
: high grade
: Tmax : 39o C
• Other symptoms : body malaise
: poor appetite
• No consult
1 day PTA
10. • Fever
• Cough
• Poor appetite
• Body malaise
• Consult AMD : PE : weak looking, dry lips
: admission
Few hours PTA
HISTORY OF PRESENT ILLNESS
11. MATERNAL HISTORY
• Mother : 27 year old
: G3P2 (2002)
• Pre-natal check up : regular
• Maternal illness : UTI
• Exposure to radiation : none
• Multivitamins : compliant
• Folic Acid : compliant
• Ferrous Sulfate : compliant
12. BIRTH HISTORY
• Full term, NSD
• Lying-in clinic
• Birth date : August 23, 2012
• BW : 3.5 kg ( 3,500 grams ) ( 7.7 lbs. )
• BL : 50 cm
• NST : normal
• NHT : not done
• Given at Birth : Vit K
: Hepa B
13. VACCINE 1ST DOSE 2ND DOSE 3RD DOSE
BCG 13 days
(9/5/2012)
Hepatitis B Birth
(8/23/2012)
2 mos & 1 day
(10/24/2012)
3 mos
(11/21/2012)
DPT 2 mos & 1 day
(10/24/2012)
3 mos
(11/21/2012)
4 mos & 12 days
(1/2/2013)
OPV 2 mos & 1 day
(10/24/2012)
3 mos
(11/21/2012)
4 mos & 12 days
(1/2/2013)
Hib 2 mos & 1 day
(10/24/2012)
3 mos
(11/21/2012)
4 mos & 12 days
(1/2/2013)
Measles 9 mos & 17 days
(6/9/2013)
MMR 1 yr & 1 mo
(9/18/13)
IMMUNIZATION HISTORY
Patient’s immunization Record
15. NUTRITIONAL HISTORY
• Breast fed : Birth until 6 mos
• Milk formula : 6 mos onwards
• Solid : 6 mos onwards
• Current diet : 8oz of milk TID
: rice, meat, fruits
• Multivitamins : Regular
16. DEVELOPMENTAL HISTORY
GROSS MOTOR ADAPTIVE FINE
MOTOR
LANGUAGE PERSONAL/SOCIAL
• Runs well
• Up, down, stairs
alone
• Imitates circular
strokes
• Draw shapes
• Combine two or
three words in
sentence
• Point to one
body part
• Removes
garment
• Toilet trained
17. ADMISSION HOSPITAL DATE AGE DIAGNOSIS
1 OLLH Feb 2013 6 months old AGE
PAST MEDICAL HISTORY
OPD CLINIC DATE AGE DIAGNOSIS
1 Other AMD Nov 2013 1 yr & 3 mos PCAP A
2 AMD Jan 2014 1 yr & 5 mos PCAP A
3 AMD Feb 2014 1 yr & 8 mos PCAP A
18. ( + ) : Asthma (Mother)
: Hypertension (Maternal grand parent)
: CVA (Maternal Grandfather)
( - ) : Mental/Psychiatric disorder
: Tuberculosis
: Diabetes mellitus
: Malignancy
: Thyroid disease
FAMILY MEDICAL HISTORY
19. • Youngest among three siblings
• Father : 60 year old
: Government employee
• Mother : 30 year old
: Call center agent
PERSONAL & SOCIAL HISTORY
20. • Home : 2-storey rented house
( with 2 siblings and 1 helper )
• Water : Refilling station
• Garbage : Collected daily
PERSONAL & SOCIAL HISTORY
21. • General: no weight loss
• Skin : no jaundice
: no bruising
• HEENT : no head injury, no trauma
: no ear discharge
: no nasal discharges, no epistaxis
: no mouth sores
: no mass
REVIEW OF SYSTEMS
22. • Neurologic : no seizure
: no loss of consciousness
• Respiratory : no colds
: no hemoptysis
Cardiovascular : no cyanosis
REVIEW OF SYSTEMS
23. • Gastrointestinal : no vomiting
: no change in bowel movement
• Musculoskeletal : no swelling
: no arthralgia
: no myalgia
: no limitation of movement
• Genitourinary : no hematuria
: no dysuria
: no polyuria
: no urinary frequency
: no foul smelling vaginal discharge
REVIEW OF SYSTEMS
24. • GENERAL SURVEY : awake, conscious, weak-looking,
carried by mother
• VITAL SIGNS : BP : 90/60 mmHg
: HR : 115 bpm
: RR : 33 cpm
: Temp : 37.8 o C
: O2 Sat : 98 %
• ANTHROPOMETRICS : Weight : 13.9 kg (z-score +1: normal)
: Height : 89 cm (z-score +1: normal)
: BMI : 17.5 kg/m2 (z-score +1: normal)
: HC : 49 cm
: CC : 51 cm
: AC : 53 cm
PHYSICAL EXAMINATION
25. • SKIN : warm, fair, no lesion, flushed skin,
good skin turgor
• HEENT : anicteric sclerae, pink palpebral conjunctivae,
no hemorrhage, no exudates, no discharges,
dry lips and oral mucosa, no oral lesions,
no lymphadenopathies
• RESPIRATORY : shallow retractions, symmetrical chest
expansion. rales on all lung fields.
• CARDIOVASCULAR : adynamic precordium, no heaves and
thrills, regular heart rhythm.
distinct heart sounds, no murmurs
PHYSICAL EXAMINATION
26. • GASTROINTESTINAL : flat, no surgical scars, normoactive
bowel sounds, no bruits, tympanitic
abdomen, no organomegaly,
no tenderness.
• EXTREMETIES : CRT <2 sec., no gross deformity,
no edema, full and equal pulses.
• GENITALIA : labia majora covers labia minora,
no vaginal discharge, no lesions
PHYSICAL EXAMINATION
27. • NEUROLOGICAL
Cerebral : GCS 15 (E4V5M6)
Cerebellar : Not done
Cranial Nerves
CN I : able to smell
CN II : intact papillary and consensual light
reflexes (+) ROR
CN III, IV, VI : full EOMs
CN V : intact; no sensory deficits
CN VII : no facial asymmetry; able to perform
different facial expressions
CN VIII : intact gross hearing
CN IX, X : intact gag reflex; uvula midline
CN XI : SCM and trapezius muscle symmetric
with muscle strength of 5/5
CN XII : tongue midline
PHYSICAL EXAMINATION
28. • NEUROLOGICAL
Motor : 5/5 on both lower and upper extremities
normal tone; no atrophy; symmetrical
movements
Sensory : responsive to light touch and pain
DTRs : ++ on biceps and knee
Meningeal Signs : no kernig’s and brudzinski’s, nuchal
rigidity
Pathologic Reflex : no babinski, clonus
PHYSICAL EXAMINATION
29. Gen. data : 2yr & 2mos old, female
CC : Cough with fever
HPI : fever (Tmax : 40OC)
: productive cough
: body malaise
: poor appetite
PE : weak-looking,
flushed skin, dry lips and
oral mucosa,
shallow retractions,
rales on all lung field,
tachypnea (33cpm)
febrile (37.8o C)
SALIENT FEATURES
30. 1. Pediatric Community Acquired Pneumonia C
2. Rule out : Dengue Fever (without warning signs)
ADMITTING DIAGNOSIS
31. 1. Pediatric Community Acquired Pneumonia C
2. Rule out : Dengue Fever without warning signs
ADMITTING DIAGNOSIS
53. PNEUMONIA
SOURCES
Pediatrics
by Nelson
Fundamentals of
Pediatrics
by Navarro
Pediatrics Infectious
Disease
By feign & cherry
Definition Inflammation of the
parenchyma of the lungs
Most common cause of
morbidity and mortality
Is an acute lung infection that
results most commonly from
viral or bacterial pathogens
Signs & Symptoms Fever
Cough
IC/SC Retraction
Cyanosis
Tachypnea
Rales/crackles
Nasal flaring
Respiratory fatigue
Fever
Chills
Cough
Retraction
Tachypnea
Restlessness
Irritability
Poor feeding
Chest indrawing
Chest pain
Hypoxemia
Tachypnea
Grunting
Fever
Cough
Retraction
Body Malaise
Tachycardia
Dyspnea
Altered mental status
Rales
Diagnostics Chest X-ray
CBC
Blood culture
Chest x-ray
ABG
CBC
Blood culture
Pulse oximetry
Chest X-ray
CBC
54. PNEUMONIA
SOURCES
Pediatrics
by Nelson
Fundamentals of
Pediatrics
by Navarro
Pediatrics Infectious
Disease
By feign & cherry
Definition Inflammation of the
parenchyma of the lungs
Most common cause of
morbidity and mortality
Is an acute lung infection that
results most commonly from
viral or bacterial pathogens
Signs & Symptoms Fever
Cough
IC/SC Retraction
Cyanosis
Tachypnea
Rales/crackles
Nasal flaring
Respiratory fatigue
Fever
Chills
Cough
Retraction
Tachypnea
Restlessness
Irritability
Poor feeding
Chest indrawing
Chest pain
Hypoxemia
Tachypnea
Grunting
Fever
Cough
Retraction
Body Malaise
Tachycardia
Dyspnea
Altered mental status
Rales
Diagnostics Chest X-ray
CBC
Blood culture
Chest x-ray
ABG
CBC
Blood culture
Pulse oximetry
Chest X-ray
CBC
55. 1. Pediatric Community Acquired Pneumonia C
2. Rule out : Dengue Fever without warning signs
ADMITTING DIAGNOSIS
57. DENGUE FEVER
Epidemiology
• Southeast Asia and Western Pacific Region
– World wide : 1.8 billion
– >70 % of the population who are at risk of dengue.
• PHILIPPINES : 2013 (127,861)
: 2014 (49,591) Jan – Aug
Department of health Philippines
58. DENGUE FEVER
Aedes Aegypti
• Daytime-biting mosquito
• highly domesticated
• breeds in water stores
– Drinking
– Washing
– container collecting fresh water
Feigin & Cherry’s, Textbook of Pediatric Infectious Diseases 7th ed.
61. DENGUE FEVER
OLD
(Revised 1997/2011 Case Definition of Dengue & Levels of Severity)
NEW
(Revised DOH/PPS Classification and Levels of severity 2011)
Case definition for Dengue Fever
Probable Dengue:
An acute febrile illness with 2 or more of the following:
• Headache
• Retro-orbital pain
• Arthralgia
• Rash
• Hemorrhagic manifestations
• Leukopenia;
AND
• Supportive serology (a reciprocal HI antibody titers ≥1280, a
comparable IgG assay ELISA titer or IgM antibody test on a late or
acute convalescent phase serum specimen
Confirmed:
A case confirmed by laboratory criteria
Case definition for Dengue with out warning signs
Probable Dengue:
Lives in or travel to dengue-endemic area, with fever, plus two of
the following:
• Headache
• Body malaise
• Myalgia
• Arthralgia
• Retro-orbital pain
• Anorexia
• Nausea
• Vomiting
• Diarrhea
• Flushed skin
• Rash (petechial, hermann’s rash)
• Tourniquet test (+)
AND
• Laboratory test, at least CBC (leukopenia with or without
thrombocytopenia) and/or dengue NS1 antigen test or dengue
IgM antibody test (optional)
Confirmed dengue:
• Viral culture isolation
• PCR
PPS Revised Dengue Guidelines 2012
62. DENGUE FEVER
OLD
(Revised 1997/2011 Case Definition of Dengue & Levels of Severity)
NEW
(Revised DOH/PPS Classification and Levels of severity 2011)
Case definition for Dengue Fever Hemorrhagic Fever (DHF)
The following must be all presented:
1. fever, or history of fever lasting 2-7 dayss, occasionally
biphasic
2. Hemorrhagic evidenced by at least one of the following:
a. (+) tourniquest test
b. Petechiae,ecchymosis, purpura
c. Bleeding from the mucosa, GIT, injection site or
other locations
d. Hematemesis or melena
3. Thrombocytopenia (100, 000 cells/mm3 or less)
4. Evidence of plasma leakage due to increased vascular
permeabilit, manifested by atleast one of the following:
a. A rise in the hematocrit equal to or greater than
20% above average for age, sex and popultion
b. A drop in the hematocrit following volume
replacement treatment equal to or greater than
20% of baseline.
c. Signs of plasma leakage such as pleural effusion
ascites and hypoproteinemia
Case definition for Dengue with warning signs
Lives or travel to dengue-endemic area with fever lasting for 2-
7 days, plus any one of the following:
• Abdominal pain or tenderness
• Persistent vomiting
• Clinical signs of fluid accumulation
• Mucosal bleeding
• Lethargy, restlessness
• Liver enlargement
• Decreased or no urine output with in 6 hours
• Laboratory: increased in HCT and or decreasing platelet
Confirmed Dengue:
• Viral culture isolation
• PCR
PPS Revised Dengue Guidelines 2012
63. DENGUE FEVER
OLD
(Revised 1997/2011 Case Definition of Dengue & Levels of Severity)
NEW
(Revised DOH/PPS Classification and Levels of severity 2011)
Case definition for Dengue Shock syndrome (DSS)
All of the four criteria for the DHF must present, plus
evidence of circulatory failure manifested by:
• Rapid and weak pulse, AND
• Narrow pulse pressure (<20mmHg )
or
manifested by:
• Hypotension for age, AND
• cold clammy skin and restlessness
Case Definition for Severe Dengue
Lives in or travel to a dengue-endemic area with fever
2- 7 days and any of the above clinical manifestations
for dengue with or without warning signs, plus any of
the following
• Severe plasma leakage, leading to:
• shock
• Fluid accumulation with respiratory distress
• Severe bleeding
• Severe organ impairment
• Liver : AST or ALT≥1000
• CNS : e.g seizures, impaired consciusness
• Heart : e.g myocarditis
• Kidney e.g renal failure
PPS Revised Dengue Guidelines 2012
64. DENGUE FEVER
OLD
(Revised 1997/2011 Case Definition of Dengue & Levels of Severity)
NEW
(Revised DOH/PPS Classification and Levels of severity 2011)
Grading of Severity of DHF/DSS
• DHF Grade 1
Fever accompanied by non specific
constitutional signs and symptoms such as
anorexia, vominting abdominal pain, the only
hemorrhagic manifestatin is a (+) tourniquet
test and or easy bruising
• DHF Grade 2
Spontaneous bleeding in addition to
manifestatations of grade 1 patient usually in
the form of skin or other hemorrhages
• DHF Grade 3 (DSS)
Circulatory failure manifested by rapid, weak
pulse and narrowing of pulse pressure or
hypotension,with the presence of cold clammy
skin and restlessness.
• DHF Grade 4 (DSS)
Profound shock with undetectable blood
pressure or pulse
PPS Revised Dengue Guidelines 2012
66. COURSE IN THE ER
DAY OF ADMISSION
S/O: CR 115 BP 90/60 O2 sat 98-99%
RR 33 T 37.8
weak-looking
dry lips
flushed skin
shallow SC retractions
rales BLF
A: PCAP C
Dengue Fever (without warning signs)
P: ADMIT
Diet
Hydration
Diagnostics
Treatment
PICTURE
67. COURSE IN THE ER
DAY OF ADMISSION
S/O: CR 115 BP 90/60 O2 sat 98-99%
RR 33 T 37.8
weak-looking
dry lips
flushed skin
shallow SC retractions
rales BLF
A: PCAP C
Dengue Fever (without warning signs)
P: ADMIT
Diet
Hydration
Diagnostics
Treatment
68. COURSE IN THE ER
DAY OF ADMISSION
S/O: CR 115 BP 90/60 O2 sat 98-99%
RR 33 T 37.8
weak-looking
dry lips
flushed skin
shallow SC retractions
rales BLF
A: PCAP C
Dengue Fever (without warning signs)
P: ADMIT
Diet
Hydration
Diagnostics
Treatment
REASONS FOR ADMISSION :
1. Moderate dehydration
2. Weak looking
3. Loss of appetite
69. COURSE IN THE ER
DAY OF ADMISSION
S/O: CR 115 BP 90/60 O2 sat 98-99%
RR 33 T 37.8
weak-looking
dry lips
flushed skin
shallow SC retractions
rales BLF
A: PCAP C
Dengue Fever (without warning signs)
P: ADMIT
Diet
Hydration
Diagnostics
Treatment
DIET :
• Diet for AGE
• No dark color foods
70. COURSE IN THE ER
DAY OF ADMISSION
S/O: CR 115 BP 90/60 O2 sat 98-99%
RR 33 T 37.8
weak-looking
dry lips
flushed skin
shallow SC retractions
rales BLF
A: PCAP C
Dengue Fever
P: ADMIT
Diet
Hydration
Diagnostics Nelson Textbook of Pediatrics 19th
ed
Treatment
ASSESSMENT OF DEGREE OF DEHYDRATION
MILD MODERATE SEVERE
Infant 5% 10% 15%
Adolescent 3% 6% 9%
Infants and young children Thirsty, alert, restless Thirst, restless or lethargic, irritable Drowsy, limp, cold, sweaty, comatose
Older children Thirsty, alert Thirst, alert Conscious, apprehensive, cold, sweaty,
cyanotic extremities
SIGNS AND SYMPTOMS
Tachycardia Absent Present Present
Palpable pulses Present Present Decreased
Blood pressure Normal Orthostatic hypotension Hypotension
Cutaneous perfusion Normal Normal Reduced and mottled
Skin turgor Normal Slight reduction Reduced
Fontanelle Normal Slightly depressed Sunken
Mucous membrane Moist Dry Very dry
Tears Present Present or absent Absent
Respirations Normal Deep, may be rapid Deep and rapid
Urine output Normal Oliguria Anuria and severe oliguria
71. COURSE IN THE ER
DAY OF ADMISSION
S/O: CR 115 BP 90/60 O2 sat 98-99%
RR 33 T 37.8
weak-looking
dry lips
flushed skin
shallow SC retractions
rales BLF
A: PCAP C
Dengue Fever
P: ADMIT
Diet
Hydration
Diagnostics Nelson Textbook of Pediatrics 19th
ed
Treatment
ASSESSMENT OF DEGREE OF DEHYDRATION
MILD MODERATE SEVERE
Infant 5% 10% 15%
Adolescent 3% 6% 9%
Infants and young children Thirsty, alert, restless Thirst, restless or lethargic, irritable Drowsy, limp, cold, sweaty, comatose
Older children Thirsty, alert Thirst, alert Conscious, apprehensive, cold, sweaty,
cyanotic extremities
SIGNS AND SYMPTOMS
Tachycardia Absent Present Present
Palpable pulses Present Present Decreased
Blood pressure Normal Orthostatic hypotension Hypotension
Cutaneous perfusion Normal Normal Reduced and mottled
Skin turgor Normal Slight reduction Reduced
Fontanelle Normal Slightly depressed Sunken
Mucous membrane Moist Dry Very dry
Tears Present Present or absent Absent
Respirations Normal Deep, may be rapid Deep and rapid
Urine output Normal Oliguria Anuria and severe oliguria
72. COURSE IN THE ER
DAY OF ADMISSION
S/O: CR 115 BP 90/60 O2 sat 98-99%
RR 33 T 37.8
weak-looking
dry lips
flushed skin
shallow SC retractions
rales BLF
A: PCAP C
Dengue Fever (without warning signs)
P: ADMIT
Diet
Hydration
Diagnostics
Treatment
HYDRATION :
Plain LR (20cc/k) fast drip
73. COURSE IN THE ER
DAY OF ADMISSION
S/O: CR 115 BP 90/60 O2 sat 98-99%
RR 33 T 37.8
weak-looking
dry lips
flushed skin
shallow SC retractions
rales BLF
A: PCAP C
Dengue Fever (without warning signs)
P: ADMIT
Diet
Hydration
Diagnostics
Treatment
CBC 10/25
Hemoglobin 129
Hematocrit 0.38
WBC 4.10 ↓
Segmenters 0.65
Stabs 0.07
Lymphocytes 0.26
Monocytes 0.02
Platelets 283,000
Dengue NS1Ag
Positive
74. DIAGNOSTIC
• Nonstructural protein 1
• 2006 : test for dengue
by Bio Rad Laboratories and Pasteur Institute
• Allows rapid detection on the D1 illness
before antibodies appear D5 illness
• NS1 antigen as an early diagnostics marker in dengue
• Comparison :
– NS1 antigen : good sensitivity (70-100%) till D3 illness
– IgM : sensitivity of 0-50% till D3 illness
Dengue NS1 Ag
Singh et al DMID 2010 Sept; 68(1):50-4)
75. COURSE IN THE ER
DAY OF ADMISSION
S/O: CR 115 BP 90/60 O2 sat 98-99%
RR 33 T 37.8
weak-looking
dry lips
flushed skin
shallow SC retractions
rales BLF
A: PCAP C
Dengue Fever (without warning signs)
P: ADMIT
Diet
Hydration
Diagnostics
Treatment
FINDINGS: Hazy infiltrates in right inner lung zone,
with confluency in right middle lobe
IMPRESSION : pneumonia right with consolidation,
right middle lobe
76. COURSE IN THE ER
DAY OF ADMISSION
S/O: CR 115 BP 90/60 O2 sat 98-99%
RR 33 T 37.8
weak-looking
dry lips
flushed skin
shallow SC retractions
rales BLF
A: PCAP C
Dengue Fever (without warning signs)
P: ADMIT
Diet
Hydration
Diagnostics
Treatment
TREATMENT :
• Cefuroxime 100 mkd
• Paracetamol 15 mkd
77. CEFUROXIME
• Class : Second generation Cephalosporins
• MOD : inhibit bacterial cell wall
• Coverage :
Gram (+) cocci : S. pneumonia
: S. pyogenes
: A. streptococci
Gram (-) cocci : N. gonorrhea
Gram (-) rods : Enterobacter aerogenes
: E. coli
: H. influenzae
: K. pneumoniae
: Proteus mirabilis
Katzung & Trevors Pharmacology 10th ed
78. CEFUROXIME
• Class : Second generation Cephalosporins
• MOD : inhibit bacterial cell wall
• Coverage :
Gram (+) cocci : S. pneumonia
: S. pyogenes
: A. streptococci
Gram (-) cocci : N. gonorrhea
Gram (-) rods : Enterobacter aerogenes
: E. coli
: H. influenzae
: K. pneumoniae
: Proteus mirabilis
Katzung & Trevors Pharmacology 10th ed
79. COURSE IN THE WARD
HOSPITAL DAY (HD) 1 (D3 illness)
S/O: CR 120 BP 100/60 UO : 1.5 ckh
RR 26 T 39
weak–looking full and equal pulses
Rales, BLF CRT <2 sec
A: PCAP C
Dengue Fever (without warning signs)
P: IVF : D5NSS 3.7 ckh
Labs : Repeat CBC w/ PLT
Meds: Cefuroxime (day 1)
Paracetamol 15mkd
80. COURSE IN THE WARD
HD 1 (D3 illness)
S/O: CR 120 BP 100/60
RR 26 T 39
weak–looking full and equal pulses
Rales, BLF CRT <2 sec
A: PCAP C
Dengue Fever (without warning signs)
P: IVF : D5NSS 3.7 ckh
Labs : Repeat CBC w/ PLT
Meds: Cefuroxime (day 1)
Paracetamol 15mkd
81. COURSE IN THE WARD
HD 1 (D3 illness)
S/O: CR 120 BP 100/60
RR 26 T 39
weak–looking full and equal pulses
Rales, BLF CRT <2 sec
A: PCAP C
Dengue Fever (without warning signs)
P: IVF : D5NSS 3.7 ckh
Labs : Repeat CBC w/ PLT
Meds: Cefuroxime (day 1)
Paracetamol 15mkd
90. COURSE IN THE WARD
HD 2(D4 illness)
S/O: CR 120 BP 90/60 abdominal distention (AC 55cm)
RR 34 T 38.8 puffy eyelids
loose watery stools, 3x rales BLF
vomits, 3x
abdominal pain
A PCAP C
Dengue Fever (with warning signs)
P: IVF: D5 NSS 3.7 4ckh Labs: Stool exam w/ CT
Meds: Cefuroxime (day 2) repeat CBC
Paracetamol 15mkd TPAG
Omeprazole 20mg IV
Albumin transfusion
Furosemide
91. COURSE IN THE WARD
HD 2(D4 illness)
S/O: CR 120 BP 90/60 abdominal distention (AC 55cm)
RR 34 T 38.8 puffy eyelids
loose watery stools, 3x rales BLF
vomits, 3x
abdominal pain
A PCAP C
Dengue Fever (with warning signs)
P: IVF: D5 NSS 3.7 4ckh Labs: Stool exam w/ CT
Meds: Cefuroxime (day 2) repeat CBC
Paracetamol 15mkd TPAG
Omeprazole 20 mg IV
Albumin transfusion
Furosemide
92. OMEPRAZOLE
Class: Proton pump inhibitor
MOA : Suppress the secretion of hydrogen ions
into the gastric lumen
• Duration of action is approximately 24h
93. COURSE IN THE WARD
HD 2(D4 illness)
S/O: CR 120 BP 90/60 abdominal distension (AC 55cm)
RR 34 T 38.8 puffy eyelids
loose watery stools, 3x rales BLF
vomits, 3x
abdominal pain
A PCAP C
Dengue Fever (with warning signs)
P: IVF: PLR 3.7 4ckh Labs: Stool exam w/ CT
Meds: Cefuroxime (day 2) repeat CBC
Paracetamol 15mkd TPAG
Omeprazole
Albumin transfusion
Furosemide
94. COURSE IN THE WARD
HD 2(D4 illness)
S/O: CR 120 BP 90/60 abdominal distention (AC 53 55cm)
RR 34 T 38.8 puffy eyelids
loose watery stools, 3x rales BLF
vomits, 3x
abdominal pain
A PCAP C
Dengue Fever
P: IVF: PLR 3.7 4ckh Labs: Stool exam w/ CT
Meds: Cefuroxime (day 2) repeat CBC
Paracetamol 15mkd TPAG
Omeprazole
Albumin transfusion
Furosemide
95. COURSE IN THE WARD
HD 2(D4 illness)
S/O: CR 120 BP 90/60 abdominal distension (AC 55cm)
RR 34 T 38.8 puffy eyelids
loose watery stools, 3x rales BLF
vomits, 3x
abdominal pain
A PCAP C
Dengue Fever
P: IVF: D5 NSS 3.7 4ckh Labs: Stool exam w/ CT
Meds: Cefuroxime (day 2) repeat CBC
Paracetamol 15mkd TPAG
Omeprazole
Albumin transfusion
Furosemide
TPAG NV 10/26
Total protein 66-87 43.6 ↓
Albumin 38-54 22.71 ↓
Globulin 23-35 20.89 ↓
A/G 1.8:1-2.3:1 1.09:1↓
96. COURSE IN THE WARD
HD 2(D4 illness)
S/O: CR 120 BP 90/60 abdominal distension (AC 55cm)
RR 34 T 38.8 puffy eyelids
loose watery stools, 3x rales BLF
vomits, 3x
abdominal pain
A PCAP C
Dengue Fever
P: IVF: D5 NSS 3.7 4ckh Labs: Stool exam w/ CT
Meds: Cefuroxime (day 2) repeat CBC
Paracetamol 15mkd TPAG
Omeprazole
Albumin transfusion
Furosemide
106. COURSE IN THE WARD
HD 3(D5 illness)
S/O: CR 164 BP 80/70 AC 55 57 cm
RR 69 T 38.6 cold clammy extremities
irritable mottled skin
weak-looking CRT > 2 sec
weak pulse
A: PCAP D
Dengue Hemorrhagic Fever III (SEVERE DENGUE)
Compensated shock
P: IVF: D5NSS 3.2 ckh 4ckh Mgt : hook to pulse oximeter
PNSS 20ck as fast drip hook to O2 via mask
Meds : Cefuroxime (day 3) Labs: Repeat CBC PT, PTT
Paracetamol Repeat TPAG D- Dimer
albumin transfusion repeat CBC repeat CXR
HCO3 correction ABG
107. COURSE IN THE WARD
HD 3(D5 illness)
S/O: CR 164 BP 80/70 AC 55 57 cm
RR 69 T 38.6 cold clammy extremities
irritable mottled skin
weak-looking CRT > 2 sec
weak pulse
A: PCAP D
Dengue Hemorrhagic Fever III (SEVERE DENGUE)
Compensated shock
P: IVF: D5NSS 3.2 ckh 4ckh Mgt : hook to pulse oximeter
PNSS 20ck as fast drip hook to O2 via mask
Meds : Cefuroxime (day 3) Labs: Repeat CBC PT, PTT
Paracetamol Repeat TPAG D- Dimer
albumin transfusion repeat CBC repeat CXR
HCO3 correction ABG
CBC 10/25 10/26
10 am
10/27
10am
10/28
5am
Hemoglobin 129 122 ↓ 129 ↑ 154 ↑
Hematocrit 0.38 0.36 ↓ 0.38 ↑ 0.46 ↑
WBC 4.10 ↓ 4.9
Segmenters 0.50 0.47
Stabs 0.07 ↑ 0.02
Lymphocytes 0.26 0.49 ↑
Monocytes 0.02 0.02
Platelets 283,000 212,000 ↓ 194,000↓ 172, 000 ↓
108. COURSE IN THE WARD
HD 3(D5 illness)
S/O: CR 164 BP 80/70 AC 55 57 cm
RR 69 T 38.6 cold clammy extremities
irritable mottled skin
weak-looking CRT > 2 sec
weak pulse
A: PCAP D
Dengue Hemorrhagic Fever III
Compensated shock
P: IVF: D5NSS 3.2 ckh 4ckh Mgt : hook to pulse oximeter
PNSS 20ck as fast drip O2 via mask @ 6-7 lpm
Meds : Cefuroxime (day 3) Labs: Repeat CBC PT, PTT
Paracetamol Repeat TPAG D- Dimer
albumin transfusion repeat CBC repeat CXR
HCO3 correction ABG
TPAG NV 10/26 10/28
Total protein 66-87 43.6 ↓ 39.3 ↓
Albumin 38-54 22.71 ↓ 23.16 ↓
Globulin 23-35 20.89 ↓ 16.14 ↓
A/G 1.8:1-2.3:1 1.09:1 ↓ 1.43:1 ↓
109. COURSE IN THE WARD
HD 3(D5 illness)
S/O: CR 164 BP 80/70 AC 55 57 cm
RR 69 T 38.6 cold clammy extremities
irritable mottled skin
weak-looking CRT > 2 sec
weak pulse
A: PCAP D
Dengue Hemorrhagic Fever III (SEVERE DENGUE)
Compensated shock
P: IVF: D5NSS 3.2 ckh 4ckh Mgt : hook to pulse oximeter
PNSS 20ck as fast drip O2 via mask @ 6-7 lpm
Meds : Cefuroxime (day 3) Labs: Repeat CBC PT, PTT
Paracetamol Repeat TPAG D- Dimer
albumin transfusion repeat CBC repeat CXR
HCO3 correction ABG
110. COURSE IN THE WARD
HD 3(D5 illness)
S/O: CR 164 BP 80/70 AC 55 57 cm
RR 69 T 38.6 cold clammy extremities
irritable mottled skin
weak-looking CRT > 2 sec
weak pulse
A: PCAP D
Dengue Hemorrhagic Fever III (SEVERE DENGUE)
Compensated shock
P: IVF: D5NSS 3.2 ckh 4ckh Mgt : hook to pulse oximeter
PNSS 20ck as fast drip O2 via mask @ 6-7 lpm
Meds : Cefuroxime (day 3) Labs: Repeat CBC PT, PTT
Paracetamol Repeat TPAG D- Dimer
albumin transfusion repeat CBC repeat CXR
HCO3 correction ABG
111. COURSE IN THE WARD
HD 3(D5 illness)
S/O: CR 164 BP 80/70 AC 55 57 cm
RR 69 T 38.6 cold clammy extremities
irritable mottled skin
weak-looking CRT > 2 sec
weak pulse
A: PCAP D
Dengue Hemorrhagic Fever III (SEVERE DENGUE)
Compensated shock
P: IVF: D5NSS 3.2 ckh 4ckh Mgt : hook to pulse oximeter
PNSS 20ck as fast drip O2 via mask @ 6-7 lpm
Meds : Cefuroxime (day 3) Labs: Repeat CBC PT, PTT
Paracetamol Repeat TPAG D- Dimer
albumin transfusion repeat CBC repeat CXR
HCO3 correction ABG
ABG 10/28
pH 7.251
pCO2
14
PO2
112.5
O2 sat 97.6
HCO3
6
TCO2
6.4
BE -21.2
Metabolic acidosis
112. COURSE IN THE WARD
HD 3(D5 illness)
S/O: CR 164 BP 80/70 AC 55 57 cm
RR 69 T 38.6 cold clammy extremities
irritable mottled skin
weak-looking CRT > 2 sec
weak pulse
A: PCAP D
Dengue Hemorrhagic Fever III(SEVERE DENGUE)
Compensated shock
P: IVF: D5NSS 3.2 ckh 4ckh Mgt : hook to pulse oximeter
PNSS 20ck as fast drip O2 via mask @ 6-7 lpm
Meds : Cefuroxime (day 3) Labs: Repeat CBC PT, PTT
Paracetamol Repeat TPAG D- Dimer
albumin transfusion repeat CBC repeat CXR
HCO3 correction ABG
113. RAPID ASSESSMENT
• Irregular respirations or rate >60
• Heart ranges:
– Child ≤2 yrs of age : <80/min or >180/min
– Child >2 yrs of age : <60/min or >160/min
• Poor perfusion with weak/absent distal pulses
• Increased work of breathing
• Cyanosis
• Altered consciousness
• Seizures
• Fever with petechiae
• Trauma
• Burns involving >10% of BSA
114. RAPID ASSESSMENT
• Irregular respirations or rate >60
• Heart ranges:
– Child ≤2 yrs of age : <80/min or >180/min
– Child >2 yrs of age : <60/min or >160/min
• Poor perfusion with weak/absent distal pulses
• Increased work of breathing
• Cyanosis
• Altered consciousness
• Seizures
• Fever with petechiae
• Trauma
• Burns involving >10% of BSA
115. CBC Assess Categorize Decide / Act
Consciousness Irritable Respiratory Distress ;
Shock
• call for help
• activate emergency
system
• hook to pulse ox &
cardiac monitor
• O2 per face mask
• SPO2 monitoring
Breathing Increased effort
Circulation pale
COURSE IN THE WARD (4pm)
Initial Assessment
116. COURSE IN THE WARD (4pm)
Primary Assessment
ABCDE Assess Categorize Decide / Act
Airway Maintainable Respiratory distress
Compensated shock
• O2 mask: 10 LPM
• IV double line
• PNSS 20 cc/kg fast
drip
• Transfer to ICU
• NPO
• Hgt monitoring
Breathing RR : 55/min
SPO2 : 95%
SC retractions
Rales
Circulation HR : 140
fair pulse
BP 80/50
CRT >2
Disability GCS 15 (E4M6V5)
Exposure Temp 39C
117. SAMPLE Assess Categorize Decide / Act
S/Sx irritable
tachypnea
Subcostal retractions
Rales, bilateral
tachycardia,
Abdominal distension
CRT > 2 sec
Respiratory distress
secondary to lung
parenchyma disease;
severe dengue with
compensated shock
• continue
medications
• continue
cardiac
monitoring
• continue SPO2
monitoring
• request for:
repeat CBC PC
PT APTT
D Dimer
Chest X ray
ABG
Allergies None
Medications Cefuroxime ; Paracetamol
Past Med Hx No PCV
Acute gastroenteritis 2013
PCAP A
(Nov 2013, Jan 2014, April
2014)
Last Meal 4 hours
COURSE IN THE WARD (4pm)
Secondary Assessment
118. SAMPLE Assess Categorize Decide / Act
Events Respiratory distress
Worsened work of breathing
Respiratory distress
secondary to lung
parenchyma disease;
severe dengue with
compensated shock
• continue
medications
• continue
cardiac
monitoring
• continue SPO2
monitoring
• request for:
repeat CBC PC
PT APTT
D Dimer
Chest X ray
ABG
COURSE IN THE WARD (4pm)
Secondary Assessment
119. PHYSICAL EXAMINATION
• BP 80/50, CR 140, RR 55, T 39OC
• pink palpebral conjunctivae, anicteric sclera, no alar flaring,
dry and pale lips and oral mucosa
• adynamic precordium, tachycardic, apex beat at 4th ICS left
mid clavicular line, no murmur
• equal chest expansion, subcostal retractions, rales both lung
fields
• distended abdomen
• fair and fast pulses, CRT > 2 seconds
• neuro exam: normal
120. Laboratory Tests Results
CBC I PC Hgb 130, hct 0.38, wbc 8.7, seg 0.32, stabs 0.08, lymph 0.59,
mono 0.01, platelet 175
Pro-thrombin Time 15 ↑
Control 11.21
INR 1.46
Protime Activity 51.5
APTT 78.3 ↑
Control 34.1
D- dimer 627.22 ↑
CXR progression of pneumonia right, mild to moderate pleural
effusion, right
ABG pH- 7.251 pCO2- 14 pO2- 112.5 O2 sat- 97.6 HCO3- 6 TCO2- 6.4
BE-(-)21.2
COURSE IN THE WARD (4pm)
Tertiary Assessment
121. Findings :
Show progression of pneumonic
infiltrates in the right middle lobe
and homogenous density in the
right hemithorax obscuring the
right cardiac border and blunting
of the right costophrenic sulcus
with lateral ascending border
pneumonia
IMPRESSION :
progression of pneumonia right,
mild to moderate pleural
effusion, right
122. 1st-12th hour of PICU stay
• awake, conscious, irritable
• VS: BP 80/50, CR 130, RR 40, T 38.9oC
• Subcostal retraction, rales
• abdominal distention
• full pulses, CRT < 2 seconds
123. CBC Assess Categorize Decide / Act
Consciousness Irritable Respiratory Distress/
failure
• call for help
• activate emergency
system
• continue O2
facemask
• continue SPO2
monitoring
Breathing labored breathing
Circulation pale
COURSE IN THE ICU (6am)13th hour
Initial Assessment
124. ABCDE Assess Categorize Decide / Act
Airway Non-Maintainable Respiratory distress
and failure 2° to lung
parenchymal disease
• intubate
• continue cardiac
monitoring
• continue SPO2
monitoring
Breathing RR : 65/min
SPO2 : 89%
SC retractions
Rales, decreased
breath sounds R
mid to base lung
Circulation HR : 168
full pulse
BP 80/50
CRT <2
Disability GCS 15 (E4M6V5)
Exposure Temp 39C
COURSE IN THE ICU (6am)
Primary Assessment
125. SAMPLE Assess Categorize Decide / Act
S/Sx irritable, weak-looking
tachypnea, increase work of
breathing (alar flaring
subcostal retractions),
decreased breath sounds mid
to base right lung field
tachycardia
Respiratory
distress/failure 2° to
lung parenchymal
disease
• shift
Cefuroxime to
Ceftriaxone
• continue
cardiac
monitoring
• continue SPO2
monitoring
• request for:
CKMB, Trop-I,
BUN, Crea,
Blood C&S,
USG
Allergies None
Medications Cefuroxime ; Paracetamol
Past Med Hx day I ICU
Last Meal 19 hours
COURSE IN THE ICU (6am)
Secondary Assessment
126. SAMPLE Assess Categorize Decide / Act
Events Severe Respiratory distress
Desaturation
Worsened work of breathing
Respiratory
distress/failure 2° to
lung parenchymal
disease
• shift
Cefuroxime to
Ceftriaxone
• continue
cardiac
monitoring
• continue SPO2
monitoring
• request for:
CKMB, Trop-I,
BUN, Crea,
Blood C&S,
USG
COURSE IN THE ICU (6am)
Secondary Assessment
127. PHYSICAL EXAMINATION
• BP 80/50, CR 160, RR 55, T 39OC
• pink palpebral conjunctivae, anicteric sclera, no alar flaring,
dry and pale lips and oral mucosa
• adynamic precordium, tachycardic, apex beat at 4th ICS left
mid clavicular line, no murmur
• labored breathing, subcostal retractions, rales both lung
fields, decreased breath sounds mid to base right lung field
• distended abdomen
• full pulses, CRT < 2 seconds
• neuro exam: normal
128. Laboratory Tests Results
CKMB 58.1
Troponin I 0.05
BUN 3.07
Creatinine 34.5
BLOOD CS negative 5 days
ABG pH- 7.352 pCO2-30.7 pO2 -95.5 O2 sat- 97.1 HCO3- 16.7 TCO2-
17.6 BE-(-)8.9
CXR no significant change in the previously noted pneumonia,
pleural effusion on the right
COURSE IN THE ICU (6am)
Tertiary Assessment
129. COURSE IN THE ICU
There is no significant change in
the previously noted pneumonia
and pleural effusion in the right,
heart and the rest of the chest
finding are unchanged
130. COURSE IN THE ICU
DAY 5, 2nd PICU DAY
Problem: PCAP D, DHF III
S/O: CR 136 BP 90/60 AC 56 57 cm
RR 51 T 37. 9 Urine output: 0.7ckh
Petechial rash , face Urine Sp.G: 1.025
Rales BLF
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P: Hydration: PNSS 10ck as fast drip Diet: milk feeding 2oz per OGT q 4h
7ckh
Labs : ABG
Meds: Ceftriaxone (day 1)
Amikacin (day 1)
Domperidone
132. COURSE IN THE ICU
DAY 6, 3rd PICU DAY
Problem: PCAP D, DHF III
S/O: CR 160 BP 90/60 AC 57 cm
RR 62 T 39 Urine output: 1.2 ckh
pale & dry lips
rales both lung field
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P: Labs : repeat CBC Hydration : D5 IMB 5ckh to KVO
repeat PT, PTT
repeat D dimer
Meds: Ceftriaxone (day 2)
Amikacin (day 2)
Furosemide
135. COURSE IN THE ICU
DAY 7, 4th PICU
S/O: CR 173 BP 80/50 AC 57 cm 55cm
RR 65 T 39 O2 sat : 70% 98%
Alar flaring
Rales BLF
Puffy eyelids
A: PCAP D
pulmonary congestion
P: Mgt : Re-intubation 4.5 depth and 13 mm, mech vent set up
NPO
Labs : repeat CXR
ABG
Meds: Ceftriaxone (day 3) Furosemide IVF Heplock
Amikacin (day 3) Dobutamine
136. CHEST X RAY
Shows significant resolution of the
previously noted right sided leural
effusion, hazy infiltrates are seen in
the right mid and both lower lobes
Imp: significant resolution of right
sided pleural effusion, new
infiltrates on right mid and both
lower lobes
138. COURSE IN THE ICU
DAY 8
S/O: CR 160 BP 110/60 AC 55cm
RR 55 T 38.9
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P: Mgt : OGT resumed
Meds: Ceftriaxone (day 4) MEROPENEM 60mkd
Amikacin (day 4)
Furosemide every 4h 8h
kalium durule every 8h
139. COURSE IN THE ICU
DAY 9
S/O: CR 128 BP 90/60 AC 55cm 53cm
RR 52 T 37.3
Rales BLF
No alar flaring
No SC retraction
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P: Mgt : continued
Meds: Meropenem(day1)
Amikacin (day 5)
Furosemide every 8h
kalium durule every 8h
140. COURSE IN THE ICU
DAY 10
S/O: CR 180 BP 90/60 AC 55cm 53cm
RR 52 T 38.4 UO 3.5ckh
Pale conjunctivae
Pale & dry lips
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P: Diagnostics: repeat CXR repeat CBC w/ PC urine KOH
repeat ABG serum Na, K
Meds: Meropenem(day2) salbutamol neb
Amikacin (day 6) dexamethasone
Furosemide every 8h
kalium durule every 8h-----12h
141. CHEST X-RAY
Partial clearing of both infiltration
right mid and both lower lobes
Imp: Partial clearing of both
infiltration right mid and both
lower lobes
145. COURSE IN THE ICU
DAY 11
S/O: CR 160 BP 90/60 AC 53cm
RR 60 afebrile
O2 sat 78%
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P: Meds: Meropenem(day 3) salbutamol neb
Amikacin (day 7) dexamethasone
Furosemide every 8h
kalium durule every 8h-----12h
Vit A 100,000 , 2 cap SD
Zinc Sulfate started
146. COURSE IN THE ICU
DAY 12
S/O: CR 110 BP 90/60 AC 53cm
RR 35 afebrile
O2 sat 99%
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P: Mgt : extubated FC removed
NGT removed----clear liquid diet w/SAP
Meds: Meropenem(day 4) salbutamol neb
Amikacin (day 8) dexamethasone
Furosemide d/c
Kalium durule every 8h-----12h
Zinc Sulfate (day 1)
147. COURSE IN THE WARD
HD 13(D15 of illness)
S/O: CR 96 BP 90/60 decreased rales
RR 31 afebrile CRT <2 sec
O2 sat 99% UO : 1.4 ckh
Equal & full pulses
A: PCAP D resolving
Dengue Hemorrhagic Fever III ( SEVERE DENGUE) resolved
P: Transferred to HDU ST. Martin
Meds: Meropenem(day 5)
Amikacin (day 9)
Zinc Sulfate (day 2)
Kalium durule d/c
FeSO4 started
148. COURSE IN THE WARD
HD 13(D15 of illness)
S/O: CR 96 BP 90/60 decreased rales
RR 31 afebrile
O2 sat 99%
A: PCAP D resolving
Dengue Hemorrhagic Fever III ( SEVERE DENGUE) resolved
P: Transferred to HDU ST. Martin
Meds: Meropenem(day 5)
Amikacin (day 9)
Zinc Sulfate (day 2)
Kalium durule d/c
FeSO4 started
149. COURSE IN THE WARD
HD 13(D15 of illness)
S/O: CR 96 BP 90/60 decreased rales
RR 31 afebrile
O2 sat 99%
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P: Transferred to ST. Martin High Dependecy Unit
Meds: Meropenem(day 5)
Amikacin (day 9)
Zinc Sulfate (day 2)
Kalium durule d/c
FeSO4 started
150. COURSE IN THE WARD
HD 14(D16 of illness)
S/O: CR 100 BP 90/60 UO : 1.4 ckh
RR 33 afebrile
decreased rales
comfortable
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P:
Meds: Meropenem(day 6)
Amikacin (day 10)
Zinc Sulfate ( day 3)
FeSO4 (day 1)
Clarithromycin 7.5mkd per orem
151. COURSE IN THE WARD
HD 15(D17 of illness)
S/O: CR 99 BP 90/60 comfortable
RR 30 afebrile clear breath sounds
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P:
Meds: Meropenem(day 7)
Amikacin (day 11)
Zinc Sulfate (day 4)
FeSO4 (day 2)
oral clarithromycin (day1)
152. COURSE IN THE WARD
HD 16(D18 of illness)
S/O: CR 99 BP 90/60
RR 30 afebrile
comfortable
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P: Diet: soft diet
Meds: Meropenem(day 8)
Amikacin discontinued
Zinc Sulfate (day 5)
FeSO4 (day 3)
oral clarithromycin (day2)
153. COURSE IN THE WARD
HD 17(D19 of illness)
S/O: Stable vital signs
A: PCAP D
Dengue Hemorrhagic Fever III ( SEVERE DENGUE)
P: Diet: soft diet
Meds: Meropenem(day 9)
Zinc Sulfate (day 5)
FeSO4 (day 3)
oral clarithromycin (day3)
MAY GO HOME
155. COMPLICATION
• Sequelae of dengue virus infection are rare
but may include the following:
– Cardiomyopathy
– Encephalopathy
– Hepatic injury
– Pneumonia
– Ophoritis/orchitis
156. PREVENT BREEDING
235
Cover water containers,
wells, and water tanks
tightly
Keep drains free from
blockage
Change the water in
vases and for aquatic
plants at least once a
week and leave no water
in the saucers
underneath the plants
Cover up tires before
disposal to prevent
water from collecting.
Dispose of unwanted
containers where water
may collect such as lunch
boxes and soft drink cans
into covered bins
Repair uneven surfaces
of the ground to prevent
water from collecting
Check whether there is
water collecting on the
tray under an air-
conditioner and in the
drainage system, and
remove stagnant water
157. PREVENT BITES
10/12/2010 236
Wear light-coloured and
long-sleeved clothing and
pants
Apply mosquito
repellents containing
DEET to exposed parts of
the body
Use mosquito nets or
screens when the room
is not air-conditioned
Avoid visiting
scrubby areas
Install screens on
windows and doors, or
place mosquito coils
/electric mosquito mats
/anti-mosquito liquid
near the windows
NS1 stands for nonstructural protein 1
full name is Platelia Dengue NS1 Ag assay, is a test for dengue made by Bio-Rad Laboratories andPasteur Institute, introduced in 2006. It allows rapid detection on the first day of fever, before antibodies appear some 5 or more days later.[1][2]
It has been adopted for use in some 40 nations. The method of detection is through enzyme-linked immunosorbent assay.[3]
India has introduced in 2010 the NS1 test costing 1,600 rupees at a private hospital in Mumbai. Now available at Rs 1100 at many private hospitals and laboratories in Delhi.Results available the same day[4]
Reasons for admission
Reasons for admission
Katzung & Trevors Pharmacology 10th ed
Katzung & Trevors Pharmacology 10th ed
Cefuroxime is a 2nd gen Cephalosphorins
Its action is to
Temp 39
Weak looking
Hematocrit decreased from 0.38-0.36
Stool exam with concentration technique
Katzung & Trevors Pharmacology 10th Edition
Temp 38.8
Loose watery stool
Abdominal pain
Hypoalbuminemia, hypoproteinemia------plasma leak into the pleural and abdominal cavities
HCT 0.35 increased to 0.38
Hematocrit decreased from 0.38-0.36
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
After 3 hours -----puffy eyelids and rales on both lung fields
FUROSEMIDE was given and BLOOD typing
emedicine.medscape.com
164
Febrile
Weak pulse
Cold clammy extremities
Mottled skin
Prolonged CRT
But BP 80/70
164
Febrile
Weak pulse
Cold clammy extremities
Mottled skin
Delayed CRT
But BP 80/70
Intubated size 4 mm depth level 10
RD appearance: may be compensating and may have tachypnea but otherwise appear normal
a child with more severe disease may be alert and interactive but anxious
RF may appear very ill and have tachypnea, sweating, half-closed eyelids, and a look that says HELP ME
a child with resp symptoms who is lethargic or unresponsive is very worrisome and suggests repiratory failure and possible imminent resp[iratoy arrest
Work of breathing-----inc RR, inc respi effort, abnormal airway and audible lung sound (grunting or wheezing) head bobbing or seesawing res[pirations .
Circulations---normal or pale skin or frank cyanosis, cyanosis or oral mucosa____ severe hypoxemia……