2. • Definition- study of what patients actually DO with
prescribed medicines.
• It integrates clinical epidemiology and clinical pharmacology.
• Methods to assess pharmionics-
1-count unused pill
2-interview/ questions/diaries
3-clinical judgement
4-measure drug conentration in plasma
3. • Usual findings are-
1 follow the prescription fully
2-accept prescription order but DONOT procure drugs
3-execute poorly
4- discontinue abruptly
– Persistence- it is time between first and last dose.
Solution-
1- Electronic medication event monitoring
2- educate about compliance.