Research and describe TWO diseases - The cardiovascular disease I chose to analyze is pericarditis. By separating the disease into its parts, the prefix peri- means surrounding. The root word is card and this means heart. We learned that a suffix -itis means inflammation (3). So pericarditis is a rare disease that can be caused by an infection where the lining surrounding the heart becomes inflamed. I also learned that a doctor will use a stethoscope to listen to heart sounds, and that pericarditis causes a specific sound, called a pericardial rub. The sound happens when the two layers of the pericardium rub against each other (4)..