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WORK UP CASE OF KERATITIS
PRESENTER-RAMJI PANDEY
(CONSULTANT
OPTOMETRIST)
Workup protocol in keratitis
• History
• Visual acuity
• Gross external examination
• slit lamp examination
• Care should be taken
• IOP
• Syringing
• Dilate the eyes for retinal evaluation
• Microbiology report
DEMOGRAPHIC DATA
M#R: xxxxx
Name: yyyyy
Age: 28
Sex: Female
D/O: 9/2/1987
Occupation: House Wife
Chief Complain
• Major Symptoms- Pain, watering, pricking
sensation, Decrease of vision, redness, pus
formation since 2 week after ocular injury by
sugar cane leaf.
Past History
H/O of ocular by injury with sugarcane leaf
since 2 weeks ago
No H/O of recent oph.consultant @ Bijnor with
Dr. Jay Prakash
Family history :- Nil
Surgeries/lasers procedure/ Allergies/ Systemic
disease/ Past surgeries / current treatment:-Nil
current treatment: using some eye drops
UVA OD OS
Distance :- 20/20 CF@CF (PL+VE,PR ACCURATE)
NI
Near :- N6 N60
with Hindi chart at 30 cm.
Retinoscopy (dry) :- plano DEFER
Acceptance Dist. :- DEFER
Near :-
IOP & time 12 Dig(N)
(mm of Hg @2:03pm)
OD OS
Lid Flat Eedema
Conjunctiva Quiet Congestion
Cornea Clear Stromal infiltrate
with epi defect
Anterior chamber PACD>1/4CT/Quiet PACD>1/4CT
Hypopyon 1mm
Pupil R/R/R r/m/f
Lens
iop
Clear
12
Clear
DIG(N)
Signs
• Feathery margins
• Immune ring
• Satellite lesions
• Endothelial plaque
• Hypopyon
CON..
 SIGNS(SPECIFIC)
• Infiltrate
• Feathery margins
• Gray/brown pigmentation
• Elevated edges
• Rough texture
• Satellite lesions
• Fixed hypopyon
Cornea, 3rd Edition
By Jay H. Krachmer, MD, Mark J. Mannis, MD, FACS and Edward J. Holland, MD
Con..
FEATHERY MARGINS BROWN PIGMENTATION ELEVATED EDGES
ROUGH TEXTURE STATELLITE LESIONS FIXED HYPOPYON
CORNEAL ULCERS Diagnosis and Managemen Namrata Sharma MD DNB MNAMS
INVESTIGATION
 SYSTEMIC INVESTIGATION-
• Blood Sugar
 OCULAR INVESTIGATION-
• Intra ocular pressure
• Slit Lamp Photo
• B-Scan
• Syringing
 MICROBIOLOGICAL INVESTIGATION
• Corneal scraping
CORNEAL ULCERS Diagnosis and Management Namrata SharmaMD DNB MNAMS
Investigation
 CULTURE MEDIA-
• 2 slides
• Blood agar
• Chocolate agar
• Sabouraud's dextrose agar(SDA)
• Brain-heart Infusion (BHI)
• Thioglycollate broth.
•
CORNEAL ULCERS Diagnosis and Management Namrata SharmaMD DNB MNAMS
Plan of treatment
• Medical Therapy- as per organism comes in
smear report and culture report
• Follow the patient to see
HERPES SIMPLEX KERATITIS
Workup protocol in viral keratitis
• History
• Visual acuity
• External examination
• Slit lamp examination
• Corneal sensation
• Rose Bengal satin
• Care should be taken
• IOP
DEMOGRAPHIC DATA
M#R: xxxxx
Name: yyyyy
Age: 28
Sex: Female
D/O: 9/2/1987
Occupation: House Wife
Chief Complain
• Major Symptoms- Pain, watering, pricking
sensation, Decrease of vision, redness, since 1
week after fever .
Past History
H/O Fever since 1 weeks ago
No H/O of recent oph.consultant dr pk pandey
where diagnosis left eye hsv keratitis
Family history :- Nil
Surgeries/lasers procedure/ Allergies/ Systemic
disease/ Past surgeries / current treatment:-Nil
current treatment: using some eye drops
UVA OD OS
Distance :- 20/20 20/40 NI
Near :- N6 N8
with Hindi chart at 30 cm.
Retinoscopy (dry) :- plano DEFER
Acceptance Dist. :- DEFER
Near :-
IOP & time 12 Dig(N)
(mm of Hg @2:03pm)
OD OS
Lid Flat Eedema
Conjunctiva Quiet Congestion
Cornea Clear Mild Stromal/
stanning+ve
dendritic pattern
Anterior chamber PACD>1/4CT/Quiet PACD>1/4C
Pupil R/R/R R/R/R
Lens
iop
Clear
12
Clear
DIG(N)
signs
• HSV keratitis is the presence of multiple small
branching epithelial dendrites on the surface of
the cornea, punctuate epithelial keratitis .
•
21
Clinical feature
• The bed of the ulcer stains with fluorescein,
while the swollen corneal epithelium at the
edge of the ulcer typically stains with rose
bengal.
• Several dendrites may also coalesce to form a
geographic epithelial ulcer.
• mild stromal edema and subepithelial
infiltration..
Symptoms
• The symptoms of herpes keratitis may include:
• Pain
• Redness
• Blurred vision
• Tearing
• Sensitivity to light
HERPES SIMPLEX KERATITIS
• HSV Keratitis is not only infectious keratitis it is also
immunologic diseases that can affect all levels of the cornea .
CLASIFICATION OF HSV KERATITIS
 Infectious epithelial keratitis
• Cornea vesicles
• Dendritic keratitis
• Geographic keratitis
• Marginal keratitis
• Neurotrophic keratopathy
 Stromal keratitis
• Necrotizing stromal keratitis
• Immune stromal (interstitial) keratitis
 Endotheliitis
• Disciform
• Diffuse
• Linear
Cornea vesicles /Punctate epithelial
keratitis
• This keratitis by swelling of the epithelium cells from intra
cellular replication of HSV.
• Initial epithelial of HSK are small vesicle that are generally
described as punctate epithelial.
• Sign - Lesion are minute
raised and vesicle.
CON..
 Dendritic ulcer- The features of a dendritic ulcer include a
branching, linear lesion and swollen epithelial borders that
contain live virus.
• This lesion represents a true ulcer in that it extends through the
basement membrane.
DIAGNOSTIC,CLINICAL TEST TEST
• Cornea sensation
• Rose Bengal satin
https://wherpes-simplex-virus-keratitis-treatment-guideline
Do’s
• Take measurement of epithelium defect and
infiltrate in every visit.
• Before putting the anesthetic drop should
check corneal sensitivity
• Always draw the diagram
• Always look for AC reaction- Measurement of
hypopyon
• Take IOP digitally
• Seidel test
Don’t
• Not checked IOP by GAT
• If perforation- defer Digitally
• Defer refraction if patient very symptomatic
• Dilatation- In COVID OPD- Not neccessery (
or as ophthal advice)
THANK YOU

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RAMJI PANDEY BY Fungel keratitis workup protocol

  • 1. WORK UP CASE OF KERATITIS PRESENTER-RAMJI PANDEY (CONSULTANT OPTOMETRIST)
  • 2. Workup protocol in keratitis • History • Visual acuity • Gross external examination • slit lamp examination • Care should be taken • IOP • Syringing • Dilate the eyes for retinal evaluation • Microbiology report
  • 3. DEMOGRAPHIC DATA M#R: xxxxx Name: yyyyy Age: 28 Sex: Female D/O: 9/2/1987 Occupation: House Wife
  • 4. Chief Complain • Major Symptoms- Pain, watering, pricking sensation, Decrease of vision, redness, pus formation since 2 week after ocular injury by sugar cane leaf.
  • 5. Past History H/O of ocular by injury with sugarcane leaf since 2 weeks ago No H/O of recent oph.consultant @ Bijnor with Dr. Jay Prakash Family history :- Nil Surgeries/lasers procedure/ Allergies/ Systemic disease/ Past surgeries / current treatment:-Nil current treatment: using some eye drops
  • 6. UVA OD OS Distance :- 20/20 CF@CF (PL+VE,PR ACCURATE) NI Near :- N6 N60 with Hindi chart at 30 cm. Retinoscopy (dry) :- plano DEFER Acceptance Dist. :- DEFER Near :- IOP & time 12 Dig(N) (mm of Hg @2:03pm)
  • 7. OD OS Lid Flat Eedema Conjunctiva Quiet Congestion Cornea Clear Stromal infiltrate with epi defect Anterior chamber PACD>1/4CT/Quiet PACD>1/4CT Hypopyon 1mm Pupil R/R/R r/m/f Lens iop Clear 12 Clear DIG(N)
  • 8. Signs • Feathery margins • Immune ring • Satellite lesions • Endothelial plaque • Hypopyon
  • 9. CON..  SIGNS(SPECIFIC) • Infiltrate • Feathery margins • Gray/brown pigmentation • Elevated edges • Rough texture • Satellite lesions • Fixed hypopyon Cornea, 3rd Edition By Jay H. Krachmer, MD, Mark J. Mannis, MD, FACS and Edward J. Holland, MD
  • 10. Con.. FEATHERY MARGINS BROWN PIGMENTATION ELEVATED EDGES ROUGH TEXTURE STATELLITE LESIONS FIXED HYPOPYON CORNEAL ULCERS Diagnosis and Managemen Namrata Sharma MD DNB MNAMS
  • 11. INVESTIGATION  SYSTEMIC INVESTIGATION- • Blood Sugar  OCULAR INVESTIGATION- • Intra ocular pressure • Slit Lamp Photo • B-Scan • Syringing  MICROBIOLOGICAL INVESTIGATION • Corneal scraping CORNEAL ULCERS Diagnosis and Management Namrata SharmaMD DNB MNAMS
  • 12. Investigation  CULTURE MEDIA- • 2 slides • Blood agar • Chocolate agar • Sabouraud's dextrose agar(SDA) • Brain-heart Infusion (BHI) • Thioglycollate broth. • CORNEAL ULCERS Diagnosis and Management Namrata SharmaMD DNB MNAMS
  • 13. Plan of treatment • Medical Therapy- as per organism comes in smear report and culture report • Follow the patient to see
  • 15. Workup protocol in viral keratitis • History • Visual acuity • External examination • Slit lamp examination • Corneal sensation • Rose Bengal satin • Care should be taken • IOP
  • 16. DEMOGRAPHIC DATA M#R: xxxxx Name: yyyyy Age: 28 Sex: Female D/O: 9/2/1987 Occupation: House Wife
  • 17. Chief Complain • Major Symptoms- Pain, watering, pricking sensation, Decrease of vision, redness, since 1 week after fever .
  • 18. Past History H/O Fever since 1 weeks ago No H/O of recent oph.consultant dr pk pandey where diagnosis left eye hsv keratitis Family history :- Nil Surgeries/lasers procedure/ Allergies/ Systemic disease/ Past surgeries / current treatment:-Nil current treatment: using some eye drops
  • 19. UVA OD OS Distance :- 20/20 20/40 NI Near :- N6 N8 with Hindi chart at 30 cm. Retinoscopy (dry) :- plano DEFER Acceptance Dist. :- DEFER Near :- IOP & time 12 Dig(N) (mm of Hg @2:03pm)
  • 20. OD OS Lid Flat Eedema Conjunctiva Quiet Congestion Cornea Clear Mild Stromal/ stanning+ve dendritic pattern Anterior chamber PACD>1/4CT/Quiet PACD>1/4C Pupil R/R/R R/R/R Lens iop Clear 12 Clear DIG(N)
  • 21. signs • HSV keratitis is the presence of multiple small branching epithelial dendrites on the surface of the cornea, punctuate epithelial keratitis . • 21
  • 22. Clinical feature • The bed of the ulcer stains with fluorescein, while the swollen corneal epithelium at the edge of the ulcer typically stains with rose bengal. • Several dendrites may also coalesce to form a geographic epithelial ulcer. • mild stromal edema and subepithelial infiltration..
  • 23. Symptoms • The symptoms of herpes keratitis may include: • Pain • Redness • Blurred vision • Tearing • Sensitivity to light
  • 24. HERPES SIMPLEX KERATITIS • HSV Keratitis is not only infectious keratitis it is also immunologic diseases that can affect all levels of the cornea .
  • 25. CLASIFICATION OF HSV KERATITIS  Infectious epithelial keratitis • Cornea vesicles • Dendritic keratitis • Geographic keratitis • Marginal keratitis • Neurotrophic keratopathy  Stromal keratitis • Necrotizing stromal keratitis • Immune stromal (interstitial) keratitis  Endotheliitis • Disciform • Diffuse • Linear
  • 26. Cornea vesicles /Punctate epithelial keratitis • This keratitis by swelling of the epithelium cells from intra cellular replication of HSV. • Initial epithelial of HSK are small vesicle that are generally described as punctate epithelial. • Sign - Lesion are minute raised and vesicle.
  • 27. CON..  Dendritic ulcer- The features of a dendritic ulcer include a branching, linear lesion and swollen epithelial borders that contain live virus. • This lesion represents a true ulcer in that it extends through the basement membrane.
  • 28. DIAGNOSTIC,CLINICAL TEST TEST • Cornea sensation • Rose Bengal satin https://wherpes-simplex-virus-keratitis-treatment-guideline
  • 29. Do’s • Take measurement of epithelium defect and infiltrate in every visit. • Before putting the anesthetic drop should check corneal sensitivity • Always draw the diagram • Always look for AC reaction- Measurement of hypopyon • Take IOP digitally • Seidel test
  • 30. Don’t • Not checked IOP by GAT • If perforation- defer Digitally • Defer refraction if patient very symptomatic • Dilatation- In COVID OPD- Not neccessery ( or as ophthal advice)