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PHARMA RESEARCH  EMERGING CHALLENGES Arulmoli,  Ph.D Vice President-R&D SeQuent Scientific Ltd., Mangalore August 19, 2011
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],PHARMA RESEARCH – EMERGING CHALLENGES Ref: IMS Health Data
[object Object],[object Object],[object Object],[object Object],Indian Pharma – Expectation in future
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],cont… Why India ?
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],cont… Why India ?
[object Object],[object Object],[object Object],[object Object],Why India ?
Status of New Molecules (NCEs) trials by Indian Cos. New Chemical Entities from Indian Pharma Companies - Status  NCEs Company Therapy area Status Target to launch Market Size Global players                     IN-105 Biocon Diabetes-Insulin  Phase -III 2011 in India US $ 13 Bn Nova Nordisk, Eli Lilly         2015 in ROW                   T 1h Biocon Psoriasis, rhematoid  Phased -II  Not mentioned US $ 15 Bn Astella, BMS, ABBOTT     arthritis   Completed     Amgen                 DRF 2593 Dr Reddy  Diabetes   Phase -III Not mentioned US $ 7 Bn Glaxo, Takeda, Abbott 307 IN   PPAR agonists       Solvay                 Crofelemer Glenmark Diarrhoea   Phase-III 2011   US $ 2 Bn Glaxo                 Sun -1334 H Sun Pharma Allergy   Phase -II Not mentioned US $ 5 Bn Sanofi-Aventis, Pfizer       Completed       P 276 Piramal Life Cancer   Phase -II To file for market US $ 48 Bn Roche, Eli Lilly, Pfizer         approval in 2011   Glaxo                 GRC 8200 Glenmark Diabetes   Phase-II  2013-14   US $ 1-2 Bn Merck       DPP IV inhibitor Completed                     Arterolane  Ranbaxy Malaria   Phase -III To apply for market  US $ 1 Bn Novartis   Maleate +       approval in 2010     Piperaquine                  
NCEs From Global Pharma cont…
NCEs From Global Pharma cont…
[object Object],[object Object],[object Object],NCE: Cost and Time to bring to Market
Traditional Pharmaceutical R&D
[object Object]
[object Object],[object Object],[object Object],Challenges to overcome the failure rate
[object Object],[object Object],[object Object],[object Object],Challenges to overcome the failure rate
Educational institutional role  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Educational institutions role: ,[object Object],[object Object],[object Object],[object Object],[object Object]
Educational institutions role ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Innovation challenges
Awareness on Intellectual Property  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IP Knowledge –  We must do…. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Empower using IP Knowledge ,[object Object],[object Object],[object Object]
Pharma research Students role….. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Government role  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Govt’s Role
Govt’s Role to control drug price
Summary  ,[object Object],[object Object]
Thanking you for your attention

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Dr. ta presentatio

  • 1. PHARMA RESEARCH EMERGING CHALLENGES Arulmoli, Ph.D Vice President-R&D SeQuent Scientific Ltd., Mangalore August 19, 2011
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7. Status of New Molecules (NCEs) trials by Indian Cos. New Chemical Entities from Indian Pharma Companies - Status NCEs Company Therapy area Status Target to launch Market Size Global players                     IN-105 Biocon Diabetes-Insulin Phase -III 2011 in India US $ 13 Bn Nova Nordisk, Eli Lilly         2015 in ROW                   T 1h Biocon Psoriasis, rhematoid Phased -II Not mentioned US $ 15 Bn Astella, BMS, ABBOTT     arthritis   Completed     Amgen                 DRF 2593 Dr Reddy Diabetes   Phase -III Not mentioned US $ 7 Bn Glaxo, Takeda, Abbott 307 IN   PPAR agonists       Solvay                 Crofelemer Glenmark Diarrhoea   Phase-III 2011   US $ 2 Bn Glaxo                 Sun -1334 H Sun Pharma Allergy   Phase -II Not mentioned US $ 5 Bn Sanofi-Aventis, Pfizer       Completed       P 276 Piramal Life Cancer   Phase -II To file for market US $ 48 Bn Roche, Eli Lilly, Pfizer         approval in 2011   Glaxo                 GRC 8200 Glenmark Diabetes   Phase-II 2013-14   US $ 1-2 Bn Merck       DPP IV inhibitor Completed                     Arterolane Ranbaxy Malaria   Phase -III To apply for market US $ 1 Bn Novartis   Maleate +       approval in 2010     Piperaquine                  
  • 8. NCEs From Global Pharma cont…
  • 9. NCEs From Global Pharma cont…
  • 10.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
  • 26. Govt’s Role to control drug price
  • 27.
  • 28. Thanking you for your attention