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PS409
   Psychology, Science,
     & Pseudoscience



           Dr Brian Hughes
              School of Psychology

brian.hughes@nuigalway.ie            @b_m_hughes
Case Studies:
Examples of Psychology-related
       Pseudoscience
Case Studies from
  Outside Mainstream Psychology:
1. Complementary and alternative
      medicine/therapies
CAM efficacy: Acupuncture
Plausibility issues:
    Qi, yin, yang, meridians
    Poor inter-rater agreement
Empirical issues:
    Cochrane Library: 16 reviews
       3 reviews for pain:
          63 trials; 4,096 participants
          No effect
       1 review for smoking cessation:
          24 trials
          No effect
CAM efficacy: Acupuncture
Adverse effects
(Noeheim & Fonnebo, 1995; Yamashita et al., 1998)

Exaggerations?
     Anaesthesia
     Chinese authenticity vs. Western
     romanticism
     Impact on health in China

Endorsement by health insurers
     Actuarial logic rather than concern for
     efficacy

Endorsement by medical authorities
     Populism or evidence?
CAM efficacy: Acupuncture
                      Ireland              China               India           Cuba
Annual health         $2,496               $278                $82             $251
spend per
capita*
Life expectancy       75/81                70/74               61/63           75/80
(M/F), yrs
Child mortality       7/5                  27/36               81/89           8/7
(M/F), per 1000
Adult mortality       105/60               158/99              275/202         131/85
(M/F), per 1000
TB cases, per         11                   101                 168             10
100,000
Last polio case       1965                 1999                2006            1962
reported

*“International Dollars” = US dollars, corrected for purchasing power parity
(i.e., figure shown refers to amount purchased in terms of US market values)
                                                                                Source: WHO
CAM efficacy: Acupuncture
             “Approved” by the BMA
                Reasons given:
                   Popularity among physicians
                   Popularity among public
                   Reported efficacy for, e.g., back pain
                   (citing Ernst & White, 1998)




   2000
CAM efficacy: Chiropractic
Plausibility issues:
    Form-function relationship,
    subluxations, bodily intelligence,
    homuncularity

Empirical issues:
    Cochrane Library: 1 review
       Dysmenorrhoea
          5 trials, 236 participants
          No effect
    Other frequently cited review:
       Shekelle et al. (1992)
          No chiropractic among
          successful trials
CAM efficacy: Chiropractic
CAM efficacy: Chiropractic
Other reviews
   Pain: Ernst (2003); Gay et al.
   (2005); Lisi et al. (2005)
      50 trials
      No effect
   Asthma: Ernst & Harkness (2001)
      2 separate studies
      No effect
CAM efficacy: Chiropractic
Cost-benefit analysis?
   Adverse effects of chiropractic
      1 per 2 million manipulations
      (Powell et al., 1993)
      1 per 400,000 manipulations
      (Dvorak, 1985)
Placebos
   Inert substances that cause symptom relief
        “My headache went away after having a sugar pill”

   Substances/procedures that cause changes in a
   symptom not directly attributable to specific or real
   pharmacological/curative action
        “My headache went away after I had my hip operation”

   Any therapy that is deliberately used for its non-
   specific psychological or physiological effects
        “My headache went away after I had my bath”



After Ogden (2004)
Placebos

 Patient characteristics
 Treatment characteristics
    Convincingness
       e.g., ultrasound for pain (Hashish et al., 1988)
    Seriousness
       e.g., placebo heart surgery (Cobb et al., 1959; Diamond et al., 1960)

 Patient-treatment interaction characteristics
     Expectancy effects
       e.g., Beta-blocker Trial (Horwitz et al., 1990)
Acupuncture placebos: Sham needles
From:
Kienle & Kiene
(1997)
Complementary and alternative
medicine/therapies
PS409
   Psychology, Science,
     & Pseudoscience



           Dr Brian Hughes
              School of Psychology

brian.hughes@nuigalway.ie            @b_m_hughes

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Psychology, Science, and Pseudoscience: Class #12 (CAM cont.)

  • 1. PS409 Psychology, Science, & Pseudoscience Dr Brian Hughes School of Psychology brian.hughes@nuigalway.ie @b_m_hughes
  • 2. Case Studies: Examples of Psychology-related Pseudoscience
  • 3. Case Studies from Outside Mainstream Psychology: 1. Complementary and alternative medicine/therapies
  • 4. CAM efficacy: Acupuncture Plausibility issues: Qi, yin, yang, meridians Poor inter-rater agreement Empirical issues: Cochrane Library: 16 reviews 3 reviews for pain: 63 trials; 4,096 participants No effect 1 review for smoking cessation: 24 trials No effect
  • 5. CAM efficacy: Acupuncture Adverse effects (Noeheim & Fonnebo, 1995; Yamashita et al., 1998) Exaggerations? Anaesthesia Chinese authenticity vs. Western romanticism Impact on health in China Endorsement by health insurers Actuarial logic rather than concern for efficacy Endorsement by medical authorities Populism or evidence?
  • 6. CAM efficacy: Acupuncture Ireland China India Cuba Annual health $2,496 $278 $82 $251 spend per capita* Life expectancy 75/81 70/74 61/63 75/80 (M/F), yrs Child mortality 7/5 27/36 81/89 8/7 (M/F), per 1000 Adult mortality 105/60 158/99 275/202 131/85 (M/F), per 1000 TB cases, per 11 101 168 10 100,000 Last polio case 1965 1999 2006 1962 reported *“International Dollars” = US dollars, corrected for purchasing power parity (i.e., figure shown refers to amount purchased in terms of US market values) Source: WHO
  • 7. CAM efficacy: Acupuncture “Approved” by the BMA Reasons given: Popularity among physicians Popularity among public Reported efficacy for, e.g., back pain (citing Ernst & White, 1998) 2000
  • 8. CAM efficacy: Chiropractic Plausibility issues: Form-function relationship, subluxations, bodily intelligence, homuncularity Empirical issues: Cochrane Library: 1 review Dysmenorrhoea 5 trials, 236 participants No effect Other frequently cited review: Shekelle et al. (1992) No chiropractic among successful trials
  • 10. CAM efficacy: Chiropractic Other reviews Pain: Ernst (2003); Gay et al. (2005); Lisi et al. (2005) 50 trials No effect Asthma: Ernst & Harkness (2001) 2 separate studies No effect
  • 11. CAM efficacy: Chiropractic Cost-benefit analysis? Adverse effects of chiropractic 1 per 2 million manipulations (Powell et al., 1993) 1 per 400,000 manipulations (Dvorak, 1985)
  • 12. Placebos Inert substances that cause symptom relief “My headache went away after having a sugar pill” Substances/procedures that cause changes in a symptom not directly attributable to specific or real pharmacological/curative action “My headache went away after I had my hip operation” Any therapy that is deliberately used for its non- specific psychological or physiological effects “My headache went away after I had my bath” After Ogden (2004)
  • 13. Placebos Patient characteristics Treatment characteristics Convincingness e.g., ultrasound for pain (Hashish et al., 1988) Seriousness e.g., placebo heart surgery (Cobb et al., 1959; Diamond et al., 1960) Patient-treatment interaction characteristics Expectancy effects e.g., Beta-blocker Trial (Horwitz et al., 1990)
  • 17. PS409 Psychology, Science, & Pseudoscience Dr Brian Hughes School of Psychology brian.hughes@nuigalway.ie @b_m_hughes