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Blt19 14 Jan 09 A Prof Raymond Lin Respiratory Tract Infections

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R
R Lin

lecture for Ngee Ann students

Santé & MédecineBusiness
1  sur  10
Antiviral resistance of influenza viruses in Singapore 3rd Meeting of National Influenza Centres in the Western Pacific and South-East Asia Regions May 5-8, 2009
Background ,[object Object],[object Object],[object Object],[object Object]
Methods ,[object Object],[object Object]
Markers of admantanes resistance ,[object Object],[object Object],* Alone or combined (e.g V27A and S31N); * Confers cross-resistance to amantadine and rimantadine E G 34 N S 31  V or T A 30 A V 27 F L 26 Mutant Wild type Position
Results of S31N in 2008 32 1 No. of Mutant 100% 32 H3N2 17% 6 H1N1 % of Mutant No. tested Subtype
Markers of neuraminidase inhibitors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Results of H275Y in H1N1 2008 2009
NAI results from WHO CC Results from WHO CC Melbourne
Future plan ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acknowledgements ,[object Object],[object Object],[object Object],[object Object],[object Object]

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Blt19 14 Jan 09 A Prof Raymond Lin Respiratory Tract Infections

  • 1. Antiviral resistance of influenza viruses in Singapore 3rd Meeting of National Influenza Centres in the Western Pacific and South-East Asia Regions May 5-8, 2009
  • 2.
  • 3.
  • 4.
  • 5. Results of S31N in 2008 32 1 No. of Mutant 100% 32 H3N2 17% 6 H1N1 % of Mutant No. tested Subtype
  • 6.
  • 7. Results of H275Y in H1N1 2008 2009
  • 8. NAI results from WHO CC Results from WHO CC Melbourne
  • 9.
  • 10.