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PHYSIOLOGY
OF
HEARING
Dr. Saaketh
Senior Resident
Dept of ENT
SOUND
• perception of pressure waves generated by vibrating air molecules
SOUND WAVES:
• Alternating Compression (dense molecules) & Rarefaction (loose
molecules) waves
• The simple sound is the sinusoidal wave or Pure Tone
WAVE PATTERNS
• A is the record of a pure tone
• B has a greater amplitude and is
louder than A.
• C has the same amplitude as A
but a greater frequency, and its
pitch is higher.
• D is a complex wave form that is
regularly repeated.
• E, which have no regular
pattern, are perceived as NOISE
HOW SENSITIVE THE EAR TO SOUNDS?
• The Human ear is sensitive to sounds over a wide range of:
- Frequencies: 20 – 20,000 Hz
- Amplitudes: 0.0002 – 200 dyne/cm2
• The human ear can detect the difference between two sounds
occurring 10 μsec apart in time
PITCH OF SOUND
• Pitch discrimination is best in the 1000- to 3000-Hz range
• Poor at high and low pitches.
• Average individuals distinguish 2000 pitchs
• Musicians- Cortical Plasticity
• The pitch of the average male voice in conversation is about 120 Hz
and Average female voice about 250 Hz.
CONDUCTION OF SOUND WAVES.
• Role of External Ear:
• Sound waves are collected by the Pinna and focused into the External
Auditory Canal
• The vibration pass down the EAC and strike the TM
EXTERNAL EAR FUNCTIONS:
• Collecting sound waves
• Amplification of frequencies
2000 - 4000 Hz (Resonant
Frequency of EAC)
• Providing cues about the
vertical localization of a sound
source (by the Degree of sound
waves reflection over the Pinna)
CONDUCTION OF SOUND WAVES.
• Conduction from tympanic
membrane to ear ossicles.
• Tympanic membrane
• Pressure Receiver – Sensitive to
Pressure Change
• Resonator – Vibrate with Pressure
Change.
• Critically Dampens as sound ends.
CONDUCTION OF SOUND WAVES MECHANICALLY
FROM MIDDLE EAR TO INNER EAR
• Impedance matching.
• Phase differential between oval
and round window.
• Natural resonance of External
Ear and Middle Ear.
• Attenuation Reflex.
IMPEDANCE MATCHING
• A person in water can not hear
sound produced out of it.
• As 99.9% sound get reflected
from surface of water due to
Impedance.
• So as Air filled Middle ear
conduct sound to fluid filled
Inner ear most of sound get
Reflected – Impedance
Mismatching.
• Compensated by Inner Ear by
IMPEDANCE MATCHING.
IMPEDANCE MATCHING BY EAR OSSICLES BY 3
MECHANISMS
• HYDROLIC ACTION OF TYMPANIC
MEMBRANE –
• Effective vibratory area of
tympanic membrane (55mm2) is
more than stapes oval window
surface area(3.2mm2)
• So force produced by sound
concentrated over small area
• Amplifying Pressure on Oval
Window
IMPEDANCE MATCHING BY EAR OSSICLES BY 3
MECHANISMS
• LEVER ACTION OF OSSICLES.
• Handle of Malleus 1.3 times
longer than Long
• process of Incus, providing
Mechanical Leverage Advantage.
• So Ossicles increases force of
movement by 1.3 times.
IMPEDANCE MATCHING BY EAR OSSICLES BY 3
MECHANISMS
• CURVED MEMBRANE EFFECT.
• Movement of Tympanic
membrane more at Periphery than
at Center where Malleus is
attached.
• So provide some leverage.
IMPEDANCE MATCHING BY EAR OSSICLES BY 3
MECHANISMS
• So all these together Increase
sound pressure 22 folds
• Impedance Mismatching is
mostly compensated.
• If remove ossicles loud sound
hear as whisper.
PHASE DIFFERENTIAL BETWEEN OVAL AND ROUND
WINDOW
• Sound don’t reach both
windows simultaneously.
• When oval window receive
compression, round window
receive rarefaction.
• If sound reaches simultaneously
no movement of Perilymph & no
hearing.
NATURAL RESONANCE OF EXTERNAL EAR AND
MIDDLE EAR
• Natural Resonance –
• allow some frequency to pass more easily to inner ear.
• External auditory canal – 3000 Hz
• Tympanic membrane – 800-1600 Hz.
• Middle ear – 800 Hz.
• Ossicular chain – 500-2000 Hz.
ATTENUATION REFLEX
• Tympanic reflex/Acoustic reflex
• Protective reflex.
• Reduces sound pressure amplitude by Changing mobility & Transmission
properties of Ear ossicles.
• Stimulus - loud sound.
• Reflex Activity – contraction of 2 muscles
• Tensor tympani
• Stapedius.
TRANSDUCTION OF SOUND WAVES
• Transduction of sound from Mechanical to Electrical occur in ORGAN
OF CORTI in inner ear.
• Vibration of Basilar membrane.
• Stimulation of hair cells
• Membrane potential change in hair cells
• Neural transmission of signals.
STIMULATION OF HAIR CELLS
• Movement of basilar membrane
causes organ of corti to move up
& down.
• Hair of the outer hair cells are
embedded in Tectorial
Membrane.
• As both Tectorial membrane &
basilar membrane moves, they
slide each other with movement.
• As organ of Corti Moves up, tectorial membrane slide foreward
moving stereocilia Awayfrom limbus.
• As organ of Corti Moves Down, tectorial membrane slide
backward moving stereocilia towardslimbus.
STIMULATION OF HAIR CELLS
• Bending of stereocilia stimulate
hair cells
• Depolarization – as stereocilia
bend away from limbus.
• Hyperpolarization – as
stereocilia bends towards
limbus.
MEMBRANE POTENTIAL CHANGE IN HAIR CELLS
• Change in membrane potential
is directly proportional to degree
of displacement.
• Describe under 2 conditions
• At rest
• During stimulation.
ENDOCOCHLEAR POTENTIAL
• Endolymph in scala media secreted by stria vascularis has High conc
of Na-K-ATPase & unique electrogenic K pump
• So it has high K conc & electrically positive to perilymph.
• So potential developed between Endolymph & Perilymph is
Endolymphatic potential or Endocochlear potential
• + 80 mv.
ACTION POTENTIAL IN HAIR CELLS
• Cochlear Microphonic potential
• Gating of K channels is
controlled by movement of
stereocilia.
• As stereocilia bend away from
Limbus – K channels open –
Depolarization.
• As stereocilia bend towards
Limbus – K channels close–
Hyperpolarization.
• Organ of corti - UP - Tectorial Membrane AWAY from Limbus -
Depolarization
• Organ of corti - DOWN - Tectorial Membrane TOWARDS from Limbus
- Hyperpolarization
UP
AWAY
D - Depolarisation
H - Hyperpolarisation
OWD
T
N
ards
AUDITORY PATHWAY:
E COLI MA
E - Eighth Nerve
C - Cochlear Nucleus
O - Olivary Nucleus
L - Lateral Lemniscus
I - Inferior Colliculus
M - Medial Geniculate Nucleus
A - Auditory Cortex
TESTS FOR HEARING
 Initial Otoscopic examination
Speech test
 Loud
 Whisper
 Tympanometry
Tuning fork test
 Weber
 Rinne
 Schwabach
 BERA
 EChocG
Audiometry
 Speech audiometry
 Pure Tone Audiometry
 OAE (Otoacoustic Emission)
Speech test
• Simplest of all
• Involves testing ability to hear
words without using any visual
information.
• Patient should repeat 5 words
spoken loudly at a distance of
approx. 5 metre
Click test
Tuning fork test
• Weber’s Test
• Vibrating tuning fork is placed on the patient's forehead (or in the middle
line).
• The vibrations are transmitted by bone conduction to cochlea
Rinne’s Test
• Compares the level of air and bone conduction of the same ear.
• base of a tuning fork is placed to the mastoid area (bone con.), and
then after the sound is no longer appreciated, the vibrating top is
placed near the external ear canal (air con.)
Schwabach’s Test
• compares the patient's bone conduction to that of the examiner's
• If the patient stops hearing before the examiner, this suggests a
sensorineural loss
• If the patient hears it longer than the examiner, this suggests a
conductive loss
Pure Tone Audiometry
• An audiometer is the electronic device which produces pure
tones.
• The amount of intensity that has to be raised above the normal
level is the measure of the degree of hearing impairment.
• It is plotted in the form of graph called
AUDIOGRAM
Air vs. Bone Conduction
• A/C (Air conduction)
• Checks the validity of entire ear system
• Tests that ipsilateral ear
B/C (Bone conduction)
• Bone vibrator is Placed on Mastoid Process
• Tests the validity of only the inner ear
• Tests better cochlea
Markings
Ranges of Hearing Loss
Normal Hearing
Conductive Hearing Loss
Sensorineural Hearing Loss
Mixed Hearing Loss
Tympanometry or impedence audiometry
• Tympanometry is an examination used to test the condition of the
middle ear and mobility of the eardrum (tympanic membrane) and
the conduction bones by creating variations of air pressure in the ear
canal.
• In evaluating hearing loss, tympanometry permits a distinction
between sensorineural and conductive hearing loss
• Introduces a pure tone into ear canal through 3-function probe tip
• Manometer (pump) varies air pressure against TM (controls
mobility)
• Speaker introduces 220Hz probe tone
• Microphone measures loudness in ear canal
types
BERA or ABR
Auditory brainstem response (ABR) audiometry is a neurologic test of
auditory brainstem function in response to auditory (click) stimuli.
Brain stem evoked response audiometry,
Auditory brain stem response, ABR audiometry,
BAER (Brainstem auditory evoked response audiometry).
First described by Jewett and Williston in 1971
Uses of BERA
1. It is an effective screening tool for evaluating cases of deafness due
to retrocochlear pathology i.e. (Acoustic schwannoma).
2. Used in screening newborns for deafness
3. Monitoting patients in intensive care units
4. Diagnosing suspected demyelination disorders

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Physiology of Hearing

  • 2. SOUND • perception of pressure waves generated by vibrating air molecules
  • 3. SOUND WAVES: • Alternating Compression (dense molecules) & Rarefaction (loose molecules) waves • The simple sound is the sinusoidal wave or Pure Tone
  • 4. WAVE PATTERNS • A is the record of a pure tone • B has a greater amplitude and is louder than A. • C has the same amplitude as A but a greater frequency, and its pitch is higher. • D is a complex wave form that is regularly repeated. • E, which have no regular pattern, are perceived as NOISE
  • 5. HOW SENSITIVE THE EAR TO SOUNDS? • The Human ear is sensitive to sounds over a wide range of: - Frequencies: 20 – 20,000 Hz - Amplitudes: 0.0002 – 200 dyne/cm2 • The human ear can detect the difference between two sounds occurring 10 μsec apart in time
  • 6. PITCH OF SOUND • Pitch discrimination is best in the 1000- to 3000-Hz range • Poor at high and low pitches. • Average individuals distinguish 2000 pitchs • Musicians- Cortical Plasticity • The pitch of the average male voice in conversation is about 120 Hz and Average female voice about 250 Hz.
  • 7. CONDUCTION OF SOUND WAVES. • Role of External Ear: • Sound waves are collected by the Pinna and focused into the External Auditory Canal • The vibration pass down the EAC and strike the TM
  • 8. EXTERNAL EAR FUNCTIONS: • Collecting sound waves • Amplification of frequencies 2000 - 4000 Hz (Resonant Frequency of EAC) • Providing cues about the vertical localization of a sound source (by the Degree of sound waves reflection over the Pinna)
  • 9. CONDUCTION OF SOUND WAVES. • Conduction from tympanic membrane to ear ossicles. • Tympanic membrane • Pressure Receiver – Sensitive to Pressure Change • Resonator – Vibrate with Pressure Change. • Critically Dampens as sound ends.
  • 10. CONDUCTION OF SOUND WAVES MECHANICALLY FROM MIDDLE EAR TO INNER EAR • Impedance matching. • Phase differential between oval and round window. • Natural resonance of External Ear and Middle Ear. • Attenuation Reflex.
  • 11. IMPEDANCE MATCHING • A person in water can not hear sound produced out of it. • As 99.9% sound get reflected from surface of water due to Impedance. • So as Air filled Middle ear conduct sound to fluid filled Inner ear most of sound get Reflected – Impedance Mismatching. • Compensated by Inner Ear by IMPEDANCE MATCHING.
  • 12. IMPEDANCE MATCHING BY EAR OSSICLES BY 3 MECHANISMS • HYDROLIC ACTION OF TYMPANIC MEMBRANE – • Effective vibratory area of tympanic membrane (55mm2) is more than stapes oval window surface area(3.2mm2) • So force produced by sound concentrated over small area • Amplifying Pressure on Oval Window
  • 13. IMPEDANCE MATCHING BY EAR OSSICLES BY 3 MECHANISMS • LEVER ACTION OF OSSICLES. • Handle of Malleus 1.3 times longer than Long • process of Incus, providing Mechanical Leverage Advantage. • So Ossicles increases force of movement by 1.3 times.
  • 14. IMPEDANCE MATCHING BY EAR OSSICLES BY 3 MECHANISMS • CURVED MEMBRANE EFFECT. • Movement of Tympanic membrane more at Periphery than at Center where Malleus is attached. • So provide some leverage.
  • 15. IMPEDANCE MATCHING BY EAR OSSICLES BY 3 MECHANISMS • So all these together Increase sound pressure 22 folds • Impedance Mismatching is mostly compensated. • If remove ossicles loud sound hear as whisper.
  • 16. PHASE DIFFERENTIAL BETWEEN OVAL AND ROUND WINDOW • Sound don’t reach both windows simultaneously. • When oval window receive compression, round window receive rarefaction. • If sound reaches simultaneously no movement of Perilymph & no hearing.
  • 17. NATURAL RESONANCE OF EXTERNAL EAR AND MIDDLE EAR • Natural Resonance – • allow some frequency to pass more easily to inner ear. • External auditory canal – 3000 Hz • Tympanic membrane – 800-1600 Hz. • Middle ear – 800 Hz. • Ossicular chain – 500-2000 Hz.
  • 18. ATTENUATION REFLEX • Tympanic reflex/Acoustic reflex • Protective reflex. • Reduces sound pressure amplitude by Changing mobility & Transmission properties of Ear ossicles. • Stimulus - loud sound. • Reflex Activity – contraction of 2 muscles • Tensor tympani • Stapedius.
  • 19. TRANSDUCTION OF SOUND WAVES • Transduction of sound from Mechanical to Electrical occur in ORGAN OF CORTI in inner ear. • Vibration of Basilar membrane. • Stimulation of hair cells • Membrane potential change in hair cells • Neural transmission of signals.
  • 20. STIMULATION OF HAIR CELLS • Movement of basilar membrane causes organ of corti to move up & down. • Hair of the outer hair cells are embedded in Tectorial Membrane. • As both Tectorial membrane & basilar membrane moves, they slide each other with movement.
  • 21. • As organ of Corti Moves up, tectorial membrane slide foreward moving stereocilia Awayfrom limbus. • As organ of Corti Moves Down, tectorial membrane slide backward moving stereocilia towardslimbus.
  • 22. STIMULATION OF HAIR CELLS • Bending of stereocilia stimulate hair cells • Depolarization – as stereocilia bend away from limbus. • Hyperpolarization – as stereocilia bends towards limbus.
  • 23. MEMBRANE POTENTIAL CHANGE IN HAIR CELLS • Change in membrane potential is directly proportional to degree of displacement. • Describe under 2 conditions • At rest • During stimulation.
  • 24. ENDOCOCHLEAR POTENTIAL • Endolymph in scala media secreted by stria vascularis has High conc of Na-K-ATPase & unique electrogenic K pump • So it has high K conc & electrically positive to perilymph. • So potential developed between Endolymph & Perilymph is Endolymphatic potential or Endocochlear potential • + 80 mv.
  • 25. ACTION POTENTIAL IN HAIR CELLS • Cochlear Microphonic potential • Gating of K channels is controlled by movement of stereocilia. • As stereocilia bend away from Limbus – K channels open – Depolarization. • As stereocilia bend towards Limbus – K channels close– Hyperpolarization.
  • 26. • Organ of corti - UP - Tectorial Membrane AWAY from Limbus - Depolarization • Organ of corti - DOWN - Tectorial Membrane TOWARDS from Limbus - Hyperpolarization UP AWAY D - Depolarisation H - Hyperpolarisation OWD T N ards
  • 27.
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  • 30. E COLI MA E - Eighth Nerve C - Cochlear Nucleus O - Olivary Nucleus L - Lateral Lemniscus I - Inferior Colliculus M - Medial Geniculate Nucleus A - Auditory Cortex
  • 32.  Initial Otoscopic examination Speech test  Loud  Whisper  Tympanometry Tuning fork test  Weber  Rinne  Schwabach  BERA  EChocG Audiometry  Speech audiometry  Pure Tone Audiometry  OAE (Otoacoustic Emission)
  • 33. Speech test • Simplest of all • Involves testing ability to hear words without using any visual information. • Patient should repeat 5 words spoken loudly at a distance of approx. 5 metre Click test
  • 34. Tuning fork test • Weber’s Test • Vibrating tuning fork is placed on the patient's forehead (or in the middle line). • The vibrations are transmitted by bone conduction to cochlea
  • 35. Rinne’s Test • Compares the level of air and bone conduction of the same ear. • base of a tuning fork is placed to the mastoid area (bone con.), and then after the sound is no longer appreciated, the vibrating top is placed near the external ear canal (air con.)
  • 36. Schwabach’s Test • compares the patient's bone conduction to that of the examiner's • If the patient stops hearing before the examiner, this suggests a sensorineural loss • If the patient hears it longer than the examiner, this suggests a conductive loss
  • 37. Pure Tone Audiometry • An audiometer is the electronic device which produces pure tones. • The amount of intensity that has to be raised above the normal level is the measure of the degree of hearing impairment. • It is plotted in the form of graph called AUDIOGRAM
  • 38. Air vs. Bone Conduction • A/C (Air conduction) • Checks the validity of entire ear system • Tests that ipsilateral ear B/C (Bone conduction) • Bone vibrator is Placed on Mastoid Process • Tests the validity of only the inner ear • Tests better cochlea
  • 45. Tympanometry or impedence audiometry • Tympanometry is an examination used to test the condition of the middle ear and mobility of the eardrum (tympanic membrane) and the conduction bones by creating variations of air pressure in the ear canal. • In evaluating hearing loss, tympanometry permits a distinction between sensorineural and conductive hearing loss
  • 46. • Introduces a pure tone into ear canal through 3-function probe tip • Manometer (pump) varies air pressure against TM (controls mobility) • Speaker introduces 220Hz probe tone • Microphone measures loudness in ear canal
  • 47. types
  • 48. BERA or ABR Auditory brainstem response (ABR) audiometry is a neurologic test of auditory brainstem function in response to auditory (click) stimuli. Brain stem evoked response audiometry, Auditory brain stem response, ABR audiometry, BAER (Brainstem auditory evoked response audiometry). First described by Jewett and Williston in 1971
  • 49.
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  • 52. Uses of BERA 1. It is an effective screening tool for evaluating cases of deafness due to retrocochlear pathology i.e. (Acoustic schwannoma). 2. Used in screening newborns for deafness 3. Monitoting patients in intensive care units 4. Diagnosing suspected demyelination disorders