Raskar TEDMED 2013

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Camera Culture Group, MIT Media Lab

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Diabetes
Syphilis
Grave’s disease
Sjogren
Marfan’s
Syndrome
Sickle Cell
Disease
Toxoplasmosis
Coagulation
Disorder
Tuberculosis
Systemic Conditions – Lagging Indicators

Hypertension
Red Spots
Blurred Vessels
Color Changes
Harrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper D
Illustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R

AIDS, CMV
Blurry vessels
“Cheese and Ketchup”
Retinography
Harrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper D
Illustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R

Red Spots
Thinner Sclera
Choroid visible (black)
Other Symptoms:
Joint Pain
Nodules in Finger Joints
early
late
Slit Lamp
Rheumatoid Arthritis
Harrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper D
Illustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R

White Ring around Cornea
Hyper- Cholesterolemia
Harrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper D
Illustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R

Tumor, Metastasis
Blurry Edges of
Optic disc
Accumulation of Fluid
Harrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper D
Illustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R

Wilsons (Metabolism)
Kayser-Fleischer Copper Ring
Harrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper D
Illustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R

Width
Branching
Flow speed
Vascular
Stroke
Heart Attack
McGeechan K et al., 2009, Ann Intern Med, Meta- Analysis: Retinal Vessel Caliber and Risk for Coronary Heart Disease
McGeechan K et al., 2009, Am J Epidemiol, Prediction of incident stroke events based on retinal vessel caliber

Direct Access: Vessels, Nerve FL
Body changes slowly
Co-located vascular + neurological
Involuntary, fine detail
Eye .. a Predictor?

Parkinson’s
Disease
Alzheimer’s
Disease
Nerve Fiber Layer
Neurological
Berisha F. et al., 2007, IOVS, Retinal Abnormalities in early Alzheimer’s Disease
Garcia-Martin E. et al., 2012, Ophthalmology, Ability and reproducibility of OCT to detect RNFL atrophy in Parkinson’s disease

Pupil opening
Eyelid
Strabismus
e.g. Myasthenia Gravis
Neuromuscular
Vaphiades MS et al., 2012, Curr Opin Ophthalmol, Ocular myasthenia gravis

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