The growing prominence of natural / herbal/ phytogenic interventions in global animal feed supplement and even therapeutic market is worth niticing , but to separate wheat from chaff on the basis of strong standarisation protocols are very important, so that the credibility of the users is not put on stake .
Role Of Validated And Standardized Herbal Products
1. R OLE OF VALIDATED AND
S TANDARDIZED H ERBAL
P RODUCTS -
A SCIENTIFIC APPROACH
Dr Capt Tanweer Alam
Head( AHP ) International Marketing
2. G ROWING I MPORTANCE
Out of 252 drugs considered basic and essential
by WHO , 11% are exclusively from plant origin
and 28% are of synthetic origin but obtained
from natural precursors
Eighty Five percent (85%) people in developing
countries still rely on traditional medicines as
first choice for human health care (WHO).
3. T HE COMPARISON OF SCOPE !
Total world population
Poultry : 19 Billion Total world population
Cattle : 1.5 billion Human: 6.88 Billion
Sheep and goat : 1.6 billion
Source: FAOSTAT website
4. H ERBAL M ARKET: A COMPARISON
Total Animal Health
Herbal Market
Total Global Herbal Market
100 Billion USD 1.5
Billion USD
Source: FAOSTAT website
& CLFMA REPORT 2009
9. G ROWING C REDENTIALS : S TANDARDIZATION &
B ETTER A NALYTICAL METHODS
10. G ROWING C REDENTIALS : S TANDARISATION &
B ETTER A NALYTICAL METHODS
A. paniculata Bacopa monnieri Zingiber officinale
11. G ROWING C REDENTIALS :
AVAILABLE T ECHNICAL B ACK - UPS
Total number of research papers listed on PubMed
containing the word "phytoconstituents."
12. G ROWING C REDENTIALS :
A RRAY OF H ERBAL M ONOGRAPHS
Publication and availability of authoritative
monographs by various organizations, improving
the scientific credibility of herbs.
13. G ROWING C REDENTIALS :
A RRAY OF H ERBAL M ONOGRAPHS
United States
Pharmacopoeia
( USP ) Europe Scientific
Cooperative
Indian Herbal on
Pharmacopoeia Phytotherapy
(ESCOP)
Confluence of
Herbal
Pharmacopoeia Chinese Herbal
British Herbal Pharmacopoeia
Pharmacopoeia
English Translation
of American Herbal
German Pharmacopoeia
Commissions ( AHP )
E monographs
14. INDIA
2,50,000 flowering plants world wide
India – 8th largest country in natural plants
One of the largest flora bio diversity
75% of the medicinal plants grow naturally
in India.
15. Scientific approch of herbal product development
17. G ENUINENESS
Test for Foreign Matter
Contaminated
(i) Foreign organs: matter coming from
the source plant but not defined as the
drug.
(ii) Foreign elements: matter not coming
from the source plant and of either
vegetable or mineral origin. (viz,. Free from
contamination
Moulds, insects and other animal
contamination.)
19. G ENUINENESS
HPTLC Finger print
Phytochemical profile checked by
Chromotographic techniques.
The samples are chromotographed reference standards
of marker constituents.
22. E FFICACY
LC/MS DETECTION:
Powerful Tool for Organic Compound Analysis
Its application is oriented towards the specific detection and potential
entification of phytomarkers in the presence of other phytochemical
23. S AFETY
• Physico-chemical [ Moisture, Ash, Acid insoluble ash,,Silica (Sand)]
• Heavy metal residues (Pb, Cd, As, Hg)
• Mycotoxin residues
• Pesticide residues (organochloro pesticides and organophosphorous
pesticides).
• Organic volatile impurities (solvent residues-wherever applicable)
• Naturally occuring toxins (like pyrrolizidine, alkaloids, beta asarone,
cynogenic glycosides etc.)
• Microbial Analysis for specific pathogens
24. CONSISTENCY
Batch to batch consistency
S – STANDARD MIX
T1- TEST SAMPLE (BATCH NO. AP/07, 24 MONTHS OLD SAMPLE)
T2- TEST SAMPLE (BATCH NO. AP/01005, 18 MONTHS OLD SAMPLE)
T3- TEST SAMPLE (BATCH NO. AP/02001, 12 MONTHS OLD SAMPLE)
T4- TEST SAMPLE (BATCH NO. AP/02006, 6 MONTHS OLD SAMPLE)
T5- TEST SAMPLE (BATCH NO. AP/02010, 1 MONTH OLD SAMPLE)
25. A BRIEF
India’s No 1 Herbal Veterinary company for
the last 60 years
Pioneers in phyto-pharmaceuticals
State-of-the-Art R&D with more than 100
qualified scientists
28. C ORPORATE S OCIAL
RESPONSIBILITY
Quarterly journal called “Journal of Natural Remedies” dedicated to
Medicinal Plant research across the globe.
A monthly magazine “Pashudhan”, dedicated to animal healthcare
since 35 years and
Launched a web portal “vetsjobsindia.com”, developed exclusively for
communicating employment opportunities to vets.
The market is increasing on all fronts. This includes consumer purchases from health food stores, drugstores, grocery stores as well as mass market outlets. Increased demand is reflected in the growth of multilevel marketers; Amway is now selling herbs! So is Shaklee and many others.It is no longer correct to say that they are going mainstream - they are mainstream!When you take aspirin for a headache, you are essentially practicing herbalism in a sense. Why? Aspirin comes from the inner bark of the Willow tree. Obviously, it does not come in the form of a tablet, but there is no denying the relief you obtain from taking it is from the plant derivative of that bark
Liquid chromatography–mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry. LC-MS is a powerful technique used for many applications which has very high sensitivity and selectivity. Its application is oriented towards the specific detection and potential identification of phytomarkers in the presence of other phytochemical (in a complex mixture). LC/MS adds additional confidence to quantification enabling to obtain limits of detection which can be up to 1000 times greater than UV detection. Sensitivity and specificity both prevail in high abundance with this detector, which decrease costs and increases confidence.