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Cleft Lip and Palate

      Dr.Chahat puri
      Intern (H.D.C)
      Sundernagar.(H.P.)
Contents
   Introduction
   Definition
   Incidence
   Etiology
   Embryology
   Classification
   Problems
    encountered
   Management
Introduction
 Orofacial clefts are the most common oro-
  facial anomaly in newborn infants and the
  second commonest congenital abnormality.
 Affecting approx one in every 800 births
  worldwide
 Non “life-threatening” abnormality,

 Can have significant effect on maternal
  bonding.
   A small proportion of oro-facial clefts may be
    associated with a genetic syndrome .
Definition
                A cleft lip or palate
                 is an abnormal
                 separation in the
                 oral-facial region
                 that happens
                 because tissue of
                 the mouth or lip
                 does not form
                 correctly in fetal
                 development.
Incidence
 For Clefts affecting the Lip only or Lip and
  Palate (CL[P]), males are more commonly
  affected than females (approx 2-1).
 Clefts palate alone (CP) is found in approx
  1 in 2000; females are more often affected
  than males.
 CL[P] varies between different ethnic
  populations.
Etiology / Causes
   1.GENETIC:-
   Mutated Inherited Genes (gene=top,
    mutation=bottom)
   2.ENVIRONMENTAL:-
   Teratogens :-Known risk in taking
    certain types of drugs during
    pregnancy .
   Link to maternal smoking.
   Alcohol use.
   Debate on the role of folic acid.
   3.OTHER SYNDROMES:-
   Stickler’s syndrome,
   Patau and Down syndrome
Embryology

   Primary Palate- Triangular area of hard
    palate anterior to incisive foramen to point
    just lateral to lateral incisor teeth
     Includes  that portion of alveolar ridge and
      four incisor teeth.
   Secondary Palate- Remaining hard palate
    and all of soft palate
Embryology
   Primary Palate
     Forms  during 4th to 7th week of Gestation
     Two maxillary swellings merge
     Two medial nasal swelling fuse
     Intermaxillary Segment Forms:
      Labial Component(Philtrum)
      Maxilla Component(Alveolus + 4 Incisors)
      Palatal Component(Triangular Primary
      Palate)
Embryology

   Secondary Palate
     Forms  in 6th to 9th weeks of gestation
     Palatal shelves change from vertical to
      horizontal position and fuse
     Tongue must migrate antero-inferiorly
Cleft Formation
 Cleft result in a deficiency of tissue
 Cleft lip occurs when an epithelial bridge fails

 Clefts of primary palate occur anterior to
  incisive foramen
 Clefts of secondary palate occur posterior to
  incisive foramen
 Secondary Palate closes 1 week later in
  females
 Cleft of lip increases likelihood of cleft of palate
  because tongue gets trapped.
Unilateral Cleft Lip
 Nasal floor communicates with oral cavity
 Maxilla on cleft side is hypoplastic.

 Columella is displaced to normal side

 Nasal ala on cleft side is laterally, posteriorly,
  and inferiorly displaced
 Lower lat on cleft side -lower, more obtuse

 Lip muscles insert into ala and columella.
Palatal Clefts

 Soft palate muscles insert on posterior
  margin of remaining hard palate rather
  than midline raphe.
 Associated Dental Abnormalities
     Supernumery   Teeth- 20%
     Dystrophic Teeth- 30%
     Missing Teeth- 50%
     Malocclusion- 100%
Classification
 DAVIS AND RICHIE (1922) ON ANATOMICAL
  BASIS:-
   Group I- Pre alveolar clefts
          (unilateral , bilateral and median.)
   Group II- post alveolar clefts
   Group III- complete alveolar clefts.
          (unilateral , bilateral and median.)
  VEAU (1931) CLASSIFICATION:-
 Group I:-clefts of soft palate only.

 Group II:-clefts of hard & soft palate.

 Group III:-complete unilateral cleft.

 Group IV:-complete bilateral alveolar
  clefts.
   KERNAHAN’S CLASSIFICATION
 FOGH ANDERSON CLASSIFICATION
          (1942):-
 Divided into
  Group – 1:-
       • LIP
          • Unilateral
          • Bilateral
    Group  – 2:-
 Lip + palate
     Unilateral
     Bilateral

    Group        – 3:-
       • Palate extending upto the incisive foramen.
Of those with CL[P]…..
approx 30% involved the lip+/-alveolus, and
70% involved lip and palate




                    GMC JAMMU
Of those with CP.....
approx 30% involved the soft palate only
and 70% involved hard and soft palate
 LAHSHAL CLASSIFICATION:-
        Given by Okriens in 1987.
    L      :     Lip
    A      :     Alveolus
    H      :     Hard Palate
    S      :     Soft Palate
    H      :     Hard Palate
    A      :     Alveolus
    L      :     Lip
   Based on the fact that cleft of lip, alveolus and
    hard palate can be bilateral and clefts
    involving soft palate are usually unilateral.
Symptoms
              Separation of the
               lip (picture)
              Separation of the
               palate (roof of the
               mouth)
              Nasal distortion
              Recurring ear
               infections
Symptoms (cont.)
   Failure to gain
    weight
   Nasal regurgitation
    when bottle feeding
   Poor speech
   Misaligned teeth
   Growth retardation
    (picture)
PROBLEMS ASSOCIATED
          Ear infections
         top picture (right=normal,
           left=infected)
          Hearing loss
          Dental cavities
          Displaced teeth (bottom
           picture)
          Poor speech
          Lip deformities
          Nasal deformities
Cleft Lip and Palate patients present a multitude
  of problems:
  Functional Impairment
       • Feeding problems:-Suckling and
         Swallowing
       • Speech
       • Hearing
       • Malocclusion
       • Respiratory infections
       • General physical development
       • Mental development.
Aesthetic Compromise


• Physiological
  implications



• Sociological
  implications
DIAGNOSIS.

   ULTRASONOGRAPHY IN
    PREGNANT FEMALES MAY
    REVEAL THE PRESENCE OF
    CLEFTS.
Ultra Sound at 18th Week
of Pregnancy
MANAGEMENT
 Successful treatment requires a MULTI
  DISCLIPLINARY APPROACH
 Starts with antenatal diagnosis and continues
  till adulthood.
 NORTHERN AND

YORKSHIRE CLEFT
LIP AND PALATE
SERVICES CRITERIA.
MANAGEMENT PROTOCOL
 BEFORE BIRTH:-ANTENATAL
  DIAGNOSIS,ULTRASONOGRAPHIST AND
  OBSTETRICIAN.
 IMMEDIATELY AFTER BIRTH:-PAEDRIATIC
  CONSULATION,COUNSELLING,FEEDING
  INSTRUCTIONS.(PRE SURGICAL
  ORTHOPEDICS)
 BIRTH-5 WEEKS:-MULTIDISCIPLINARY
  MEETING.
 6-10 WEEKS:-CLEFT LIP REPAIR,2-3 DAY
  STAY,MILLARD RULE OF 10,REMOVAL OF
 12-16 WEEKS-REVIEW AND POST OP,
                          ENT
  ASSESSMENT.
 6-18 MONTHS-SURGICAL REVIEW.

 18 MONTHS – 6 YEARS:-ENT AND PEDIATRIC
  ,DENTAL ASSESMENT.
 6-12 YEARS:-LATE PRIMARY / EARLY MIXED:-
  ENT,ORTHODONTIST,PEDODONTIST,
     PLASTIC SURGEON,PSYCHOLOGIST.
 12-18 YEARS:-LIP
  REVISION,RHINOPLASTY,OSTEOTOMY,DENT
  AL IMPLANTS.
 20 YEARS:-LOCAL COLLECTION AND FULL
 STAGE      OF TREATMENT:-
 NEONATAL PERIOD-immediate counselling,
  feeding , pre surgical orthopedics ,lip repair
  ,palate repair.
 TODDLER PERIOD:-speech therapy ,
  hearing/ear infections.
 GRADE SCHOOL PERIOD:-orthodontic
  management , ABG ,psychological growth.
 TEENAGE PERIOD:- orthognathic surgeries,

                         Rhinoplasty.
Pre surgical plates, moulding
plates, feeding plates…….




               Dr. Christine Underhill   12th July 2008
 TREATMENT
       Primary management:-
    Primary    management is done by:-
      • Millard rotational flap
      • Langenback’s operation
      • Wardill’s operation
    Cleft   palate only:-
      • Soft palate only- one operation at 6
        months
      • Soft palate & hard palate -two operation
        soft palate at 6 months  hard palate
        at 15-18 months.

   Cleft palate and cleft lip:-
    • Unilateral:- 2 operation:-
      • Cleft lip an soft palate at 5-6 months.
      • Hard palate and gum pad with or
        without lip at 15-18 months.
    • Bilateral:-    2 operation:-
      • Cleft lip and soft palate at 4-5 months.
      • Hard palate and gum pad with or
        without lip at 15-18 months
Cheilorrhaphy
 Surgical correction of cleft lip deformity.
 Early operative procedure used to correct cleft
  deformities.
 Cleft lip disrupts the important circumoral
  orbicuralis oris musculature.
 Objectives :-1.Functional-restore normal
  function and arrangement of muscle.
                2.Esthetic.-normal anatomic
  structures,cupid bow and philtrum.
Surgical technique
 Different for different types of clefts.
 In unilateral cases,unaffected side serve as a
  guide for lip length and symmetry.
 Lips closed in linear fashion.

 Restore symmetry not only to lip but also to
  the nasal tip.
 First and the most important steps in
  correcting nasal deformity.
A
Palatorrhaphy
 Performed in one operation,but occsaionally
  performed in two also.
 Two operations:-soft palate closure
  (staphylorrhaphy) performed first followed by
  hard palate closure(uranorrhaphy).
 OBJECTIVES:-speech and degluttion
  correction.
 Surgical techniques includes:-Hard palate
  closure
 Soft palate closure.
Hard palate closure(Von
langenbeck operation)
Variations of langenbeck
Triple layered soft tissue
flap
Wardill operation
Alveolar bone grafting (ABG)
   Provides continuity of alveolar ridge.
   Provides bone for canine to erupt .
   Osseous support for adjacent teeth
   Majority of canines erupt spontaneously…
    others require surgical exposure often in
    combination with orthodontics.
   The erupting teeth often appear to then
    stimulate the formation of new alveolar bone
Secondary surgical
         procedures.
 Performed after initial repair of cleft defects in
  an effort to improve speech or correct residual
  defects.
 Commonly used technique to improve
  velopharyngeal competence secondarily is the
  palatal flat procedure.
 Another technique is the placement of an
  implants behind the posterior pharyngeal wall
  to bring it anteriorly.
Conclusion
 Cleft Lip and Palate are common congenital
  deformities that often affect speech, hearing,
  and cosmesis; and may at times lead to airway
  compromise.
 Oro facial clefts require a multidisciplinary
  approach
 Treatment extends over many years and risks
  exhausting patient cooperation
 Need to keep the patients best interests in
  mind…
THANK YOU

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Chahat o.s.

  • 1. Cleft Lip and Palate Dr.Chahat puri Intern (H.D.C) Sundernagar.(H.P.)
  • 2. Contents  Introduction  Definition  Incidence  Etiology  Embryology  Classification  Problems encountered  Management
  • 3. Introduction  Orofacial clefts are the most common oro- facial anomaly in newborn infants and the second commonest congenital abnormality.  Affecting approx one in every 800 births worldwide  Non “life-threatening” abnormality,  Can have significant effect on maternal bonding.  A small proportion of oro-facial clefts may be associated with a genetic syndrome .
  • 4. Definition  A cleft lip or palate is an abnormal separation in the oral-facial region that happens because tissue of the mouth or lip does not form correctly in fetal development.
  • 5. Incidence  For Clefts affecting the Lip only or Lip and Palate (CL[P]), males are more commonly affected than females (approx 2-1).  Clefts palate alone (CP) is found in approx 1 in 2000; females are more often affected than males.  CL[P] varies between different ethnic populations.
  • 6. Etiology / Causes  1.GENETIC:-  Mutated Inherited Genes (gene=top, mutation=bottom)  2.ENVIRONMENTAL:-  Teratogens :-Known risk in taking certain types of drugs during pregnancy .  Link to maternal smoking.  Alcohol use.  Debate on the role of folic acid.  3.OTHER SYNDROMES:-  Stickler’s syndrome,  Patau and Down syndrome
  • 7. Embryology  Primary Palate- Triangular area of hard palate anterior to incisive foramen to point just lateral to lateral incisor teeth  Includes that portion of alveolar ridge and four incisor teeth.  Secondary Palate- Remaining hard palate and all of soft palate
  • 8. Embryology  Primary Palate  Forms during 4th to 7th week of Gestation  Two maxillary swellings merge  Two medial nasal swelling fuse  Intermaxillary Segment Forms: Labial Component(Philtrum) Maxilla Component(Alveolus + 4 Incisors) Palatal Component(Triangular Primary Palate)
  • 9. Embryology  Secondary Palate  Forms in 6th to 9th weeks of gestation  Palatal shelves change from vertical to horizontal position and fuse  Tongue must migrate antero-inferiorly
  • 10. Cleft Formation  Cleft result in a deficiency of tissue  Cleft lip occurs when an epithelial bridge fails  Clefts of primary palate occur anterior to incisive foramen  Clefts of secondary palate occur posterior to incisive foramen  Secondary Palate closes 1 week later in females  Cleft of lip increases likelihood of cleft of palate because tongue gets trapped.
  • 11. Unilateral Cleft Lip  Nasal floor communicates with oral cavity  Maxilla on cleft side is hypoplastic.  Columella is displaced to normal side  Nasal ala on cleft side is laterally, posteriorly, and inferiorly displaced  Lower lat on cleft side -lower, more obtuse  Lip muscles insert into ala and columella.
  • 12. Palatal Clefts  Soft palate muscles insert on posterior margin of remaining hard palate rather than midline raphe.  Associated Dental Abnormalities  Supernumery Teeth- 20%  Dystrophic Teeth- 30%  Missing Teeth- 50%  Malocclusion- 100%
  • 13. Classification  DAVIS AND RICHIE (1922) ON ANATOMICAL BASIS:-  Group I- Pre alveolar clefts (unilateral , bilateral and median.)  Group II- post alveolar clefts  Group III- complete alveolar clefts. (unilateral , bilateral and median.)
  • 14.  VEAU (1931) CLASSIFICATION:-  Group I:-clefts of soft palate only.  Group II:-clefts of hard & soft palate.  Group III:-complete unilateral cleft.  Group IV:-complete bilateral alveolar clefts.
  • 15.
  • 16. KERNAHAN’S CLASSIFICATION
  • 17.  FOGH ANDERSON CLASSIFICATION (1942):-  Divided into Group – 1:- • LIP • Unilateral • Bilateral Group – 2:-  Lip + palate  Unilateral  Bilateral Group – 3:- • Palate extending upto the incisive foramen.
  • 18. Of those with CL[P]….. approx 30% involved the lip+/-alveolus, and 70% involved lip and palate GMC JAMMU
  • 19. Of those with CP..... approx 30% involved the soft palate only and 70% involved hard and soft palate
  • 20.  LAHSHAL CLASSIFICATION:-  Given by Okriens in 1987. L : Lip A : Alveolus H : Hard Palate S : Soft Palate H : Hard Palate A : Alveolus L : Lip  Based on the fact that cleft of lip, alveolus and hard palate can be bilateral and clefts involving soft palate are usually unilateral.
  • 21. Symptoms  Separation of the lip (picture)  Separation of the palate (roof of the mouth)  Nasal distortion  Recurring ear infections
  • 22. Symptoms (cont.)  Failure to gain weight  Nasal regurgitation when bottle feeding  Poor speech  Misaligned teeth  Growth retardation (picture)
  • 23. PROBLEMS ASSOCIATED  Ear infections top picture (right=normal, left=infected)  Hearing loss  Dental cavities  Displaced teeth (bottom picture)  Poor speech  Lip deformities  Nasal deformities
  • 24. Cleft Lip and Palate patients present a multitude of problems: Functional Impairment • Feeding problems:-Suckling and Swallowing • Speech • Hearing • Malocclusion • Respiratory infections • General physical development • Mental development.
  • 25. Aesthetic Compromise • Physiological implications • Sociological implications
  • 26. DIAGNOSIS.  ULTRASONOGRAPHY IN PREGNANT FEMALES MAY REVEAL THE PRESENCE OF CLEFTS.
  • 27. Ultra Sound at 18th Week of Pregnancy
  • 28. MANAGEMENT  Successful treatment requires a MULTI DISCLIPLINARY APPROACH  Starts with antenatal diagnosis and continues till adulthood.  NORTHERN AND YORKSHIRE CLEFT LIP AND PALATE SERVICES CRITERIA.
  • 29. MANAGEMENT PROTOCOL  BEFORE BIRTH:-ANTENATAL DIAGNOSIS,ULTRASONOGRAPHIST AND OBSTETRICIAN.  IMMEDIATELY AFTER BIRTH:-PAEDRIATIC CONSULATION,COUNSELLING,FEEDING INSTRUCTIONS.(PRE SURGICAL ORTHOPEDICS)  BIRTH-5 WEEKS:-MULTIDISCIPLINARY MEETING.  6-10 WEEKS:-CLEFT LIP REPAIR,2-3 DAY STAY,MILLARD RULE OF 10,REMOVAL OF
  • 30.  12-16 WEEKS-REVIEW AND POST OP, ENT ASSESSMENT.  6-18 MONTHS-SURGICAL REVIEW.  18 MONTHS – 6 YEARS:-ENT AND PEDIATRIC ,DENTAL ASSESMENT.  6-12 YEARS:-LATE PRIMARY / EARLY MIXED:- ENT,ORTHODONTIST,PEDODONTIST, PLASTIC SURGEON,PSYCHOLOGIST.  12-18 YEARS:-LIP REVISION,RHINOPLASTY,OSTEOTOMY,DENT AL IMPLANTS.  20 YEARS:-LOCAL COLLECTION AND FULL
  • 31.  STAGE OF TREATMENT:-  NEONATAL PERIOD-immediate counselling, feeding , pre surgical orthopedics ,lip repair ,palate repair.  TODDLER PERIOD:-speech therapy , hearing/ear infections.  GRADE SCHOOL PERIOD:-orthodontic management , ABG ,psychological growth.  TEENAGE PERIOD:- orthognathic surgeries, Rhinoplasty.
  • 32. Pre surgical plates, moulding plates, feeding plates……. Dr. Christine Underhill 12th July 2008
  • 33.  TREATMENT  Primary management:- Primary management is done by:- • Millard rotational flap • Langenback’s operation • Wardill’s operation Cleft palate only:- • Soft palate only- one operation at 6 months • Soft palate & hard palate -two operation soft palate at 6 months  hard palate at 15-18 months.
  • 34.   Cleft palate and cleft lip:- • Unilateral:- 2 operation:- • Cleft lip an soft palate at 5-6 months. • Hard palate and gum pad with or without lip at 15-18 months. • Bilateral:- 2 operation:- • Cleft lip and soft palate at 4-5 months. • Hard palate and gum pad with or without lip at 15-18 months
  • 35. Cheilorrhaphy  Surgical correction of cleft lip deformity.  Early operative procedure used to correct cleft deformities.  Cleft lip disrupts the important circumoral orbicuralis oris musculature.  Objectives :-1.Functional-restore normal function and arrangement of muscle.  2.Esthetic.-normal anatomic structures,cupid bow and philtrum.
  • 36. Surgical technique  Different for different types of clefts.  In unilateral cases,unaffected side serve as a guide for lip length and symmetry.  Lips closed in linear fashion.  Restore symmetry not only to lip but also to the nasal tip.  First and the most important steps in correcting nasal deformity.
  • 37. A
  • 38. Palatorrhaphy  Performed in one operation,but occsaionally performed in two also.  Two operations:-soft palate closure (staphylorrhaphy) performed first followed by hard palate closure(uranorrhaphy).  OBJECTIVES:-speech and degluttion correction.  Surgical techniques includes:-Hard palate closure  Soft palate closure.
  • 41.
  • 42. Triple layered soft tissue flap
  • 44. Alveolar bone grafting (ABG)  Provides continuity of alveolar ridge.  Provides bone for canine to erupt .  Osseous support for adjacent teeth  Majority of canines erupt spontaneously… others require surgical exposure often in combination with orthodontics.  The erupting teeth often appear to then stimulate the formation of new alveolar bone
  • 45. Secondary surgical procedures.  Performed after initial repair of cleft defects in an effort to improve speech or correct residual defects.  Commonly used technique to improve velopharyngeal competence secondarily is the palatal flat procedure.  Another technique is the placement of an implants behind the posterior pharyngeal wall to bring it anteriorly.
  • 46. Conclusion  Cleft Lip and Palate are common congenital deformities that often affect speech, hearing, and cosmesis; and may at times lead to airway compromise.  Oro facial clefts require a multidisciplinary approach  Treatment extends over many years and risks exhausting patient cooperation  Need to keep the patients best interests in mind…