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PLEURA AND PLEURAL CAVITY
PLEURA
 Pleural cavity is lined by
single layer of flat cells,
“mesothelium” and an
associated layer of
supporting connective
tissue; together they form
pleura.
PLEURA
 parietal pleura :pleura
associated with the
walls of a pleural cavity
 visceral pleura :pleura,
which adheres to and
covers the lung: reflects
from the medial wall
and onto the surface of
the lung
DEVELOPMENT OF PLEURA
 each lung bud
invaginates the wall of
coelomic cavity and then
grows to fill a greater
part of the cavity
 lung is covered with
visceral pleura and the
thoracic wall is lined with
parietal pleura
 original coelomic cavity
is reduced to slitlike
space called the pleural
cavity as a result of the
growth of the lung.
SUPRAPLEURAL MEMBRANE
 thickening of connective
tissue that covers the
apex of lung
 extension of
endothoracic fascia that
exists between parietal
pleura and thoracic
cage
 extends between inner
border of first rib and
transverse process of
C7 vertebra
 act as a rigid barrier so
as to prevent changes
in intrathoracic
pressure drawing upon
the contents of the neck
PARTS OF PARIETAL PLEURA
 costal part
 diaphragmatic
part
 mediastinal part
 cervical pleura
CUPOLA OR CERVICAL PART
 the dome-shaped
layer of parietal pleura
lining the cervical
extension of the
pleural cavity
 cervical pleura
extends up into the
neck, lining the
undersurface of the
suprapleural
membrane It reaches
a level 1 to 1.5 in. (2.5
to 4 cm) above the
MEDIASTINAL PART
pleura
covering the
mediastinum
COSTAL PART
 pleura related to the
ribs and intercostal
spaces
DIAPHRAGMATIC PART
 pleura covering
the diaphragm
REFLECTIONS OF PARIETAL PLEURA
 Superiorly: pleural cavity
can project as much as 3-
4 cm above the first
costal cartilage
 Anteriorly: pleural
cavities approach
each other posterior
to the upper part of
the sternum. posterior
to the lower part of
the sternum, the
parietal pleura does
not come as close to
the midline on the left
side
 Inferiorly: In the
midclavicular line, the
pleural cavity extends
inferiorly to rib VIII. In
the midaxillary line, it
extends to rib X. From
this point, the inferior
margin courses
horizontally, to reach
vertebra XII
VISCERAL PLEURA
o Visceral pleura is
continuous with
parietal pleura at the
hilum of each lung.
o The visceral pleura is
firmly attached to the
surface of the lung,
including both
opposed surfaces of
the fissures that divide
the lungs into lobes.
PULMONARY LIGAMENT
 The parietal pleura
surrounding the root
of the lung extends
downwards beyond
the root as a fold
called the pulmonary
ligament.
 The fold contains a
thin layer of loose
areolar tissue with a
few lymphatics
 Actually it provides a dead
space into which the
pulmonary veins can expand
during increased venous
return as in exercise.
 The lung roots can also
descend into it with the
descent of the diaphragm
NERVE SUPPLY OF THE PLEURA
The parietal pleura is
sensitive to pain,
temperature, touch, and
pressure
 The costal pleura is
segmentally supplied by
the intercostal nerves.
 The mediastinal pleura is
supplied by the phrenic
nerve.
 The diaphragmatic pleura
is supplied over the
domes by the phrenic
nerve and around the
periphery by the lower six
NERVE SUPPLY OF VISCERAL
PLEURA
 The visceral pleura
covering the lungs is
sensitive to stretch but
is insensitive to
common sensations
such as pain and
touch.
 It receives an
autonomic nerve
supply from the
pulmonary plexus
BLOOD SUPPLY
 The parietal pleura is
supplied by
intercostal, internal
thoracic and
musculophrenic
arteries.
 The veins drain
mostly into the azygos
and internal thoracic
veins.
 The pulmonary
pleura, like the lung, is
supplied by the
bronchial arteries
LYMPHATIC DRAINAGE
 PARIETAL PLEURA:
The lymphatics drain
into the intercostal,
internal mammary,
posterior mediastinal
and diaphragmatic
nodes.
 VISCERAL PLEURA:
It is drained by the
bronchopulmonary
lymph nodes.
PLEURAL CAVITY
 Two pleural cavities
are situated on either
side of the
mediastinum
 During development,
the lungs grow out of
the mediastinum,
becoming surrounded
by the pleural cavities.
As a result, the outer
surface of each organ
is covered by pleura
 Each lung remains
attached to the
mediastinum by a root
formed by the airway,
pulmonary blood
vessels, lymphatic
tissues, and nerves
 Only a potential space
normally exists
between the visceral
pleura covering lung
and the parietal
pleura lining the wall
of the thoracic cavity
 Two pleural cavities,
one on either side of the
mediastinum, surround
the lungs
 superiorly: extend
above rib I into the root
of the neck
 inferiorly: they extend to
a level just above the
costal margin
 medialy: wall of each
pleural cavity is the
mediastinum
PLEURAL RECESSES
 The lungs do not completely fill the anterior or
posterior inferior regions of the pleural cavities
 This results in recesses in which two layers of
parietal pleura become opposed.
 Expansion of the lungs into these spaces usually
occurs only during forced inspiration
 the recesses provide potential spaces in which
fluids can collect and from which fluids can be
aspirated
 Costomediastinal
recesses: Anteriorly,
where costal pleura is
opposed to
mediastinal pleura.
The largest is on the
left side in the region
overlying the heart.
COSTODIAPHRAGMATIC
RECESS
 The largest and
clinically most
important
recesses
 occur in each
pleural cavity
between the
costal pleura and
diaphragmatic
pleura
 The costodiaphragmatic recesses are the regions
between the inferior margin of the lungs and
inferior margin of the pleural cavities
 They are deepest after forced expiration and
shallowest after forced inspiration
PLEURAL FLUID
 The pleural space
normally contains 5 to
10 mL of clear fluid,
which lubricates the
apposing surfaces of
the visceral and
parietal pleura during
respiratory
movements
 The formation of the
fluid results from
hydrostatic and
osmotic pressures
 Since the hydrostatic
pressures are greater
in the capillaries of the
parietal pleura than in
the capillaries of the
visceral pleura
(pulmonary
circulation), the
pleural fluid is
normally absorbed
into the capillaries of
the visceral pleura.
 Any condition that
increases the production
of the fluid (e.g.,
inflammation, malignancy,
congestive heart disease)
or impairs the drainage of
the fluid (e.g., collapsed
lung) results in the
abnormal accumulation of
fluid, called pleural
effusion
 The presence of 300 mL
of fluid in the
costodiaphragmatic
recess in an adult is
sufficient to enable its
clinical detection
 The clinical signs include
decreased lung expansion
on the side of the effusion,
with decreased breath
sounds and dullness on
 A collection of pus in the
pleural cavity is called
an empyema
 Aspiration of any fluid
from the pleural cavity is
called paracentesis
thoracis.
 It is usually done in the
8th intercostal space in
the midaxillary line. The
needle is passed
through the lower part
of the space to avoid
injury to the principal
neurovascular bundle.
PLEURISY
 Inflammation of the pleura (pleuritis or pleurisy),
secondary to inflammation of the lung, results in
the pleural surfaces becoming coated with
inflammatory exudate, causing the surfaces to be
roughened.
 This roughening produces friction, and a pleural
rub can be heard with the stethoscope on
inspiration and expiration.
 exudate becomes invaded by fibroblasts, which
lay down collagen and bind the visceral pleura to
the parietal pleura, forming pleural adhesions
PNEUMOTHORAX
 As the result of
disease or injury, air
can enter the pleural
cavity from the lungs
or through the chest
wall
 Stab wounds of the
thoracic wall may
pierce the parietal
pleura so that the
pleural cavity is open
to the outside air
 This condition is
called open
PNEUMOTHORAX
 In these circumstances, the air pressure builds up
on the wounded side and pushes the
mediastinum toward the opposite side
 In this situation, a collapsed lung is on the injured
side and the opposite lung is compressed by the
deflected mediastinum. This dangerous condition
is called a tension pneumothorax
 Air in the pleural
cavity associated with
serous fluid is known
as
hydropneumothorax,
associated with pus
as pyopneumothorax,
and associated with
blood as
hemopneumothorax
 In
hemopneumothorax,
blood enters the
pleural cavity. It can
be caused by stab or
bullet wounds to the
chest wall, resulting in
bleeding from blood
vessels in the chest
wall, from vessels in
the chest cavity, or
from a lacerated lung
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Pleura and pleural cavity copy

  • 2. PLEURA  Pleural cavity is lined by single layer of flat cells, “mesothelium” and an associated layer of supporting connective tissue; together they form pleura.
  • 3. PLEURA  parietal pleura :pleura associated with the walls of a pleural cavity  visceral pleura :pleura, which adheres to and covers the lung: reflects from the medial wall and onto the surface of the lung
  • 4. DEVELOPMENT OF PLEURA  each lung bud invaginates the wall of coelomic cavity and then grows to fill a greater part of the cavity  lung is covered with visceral pleura and the thoracic wall is lined with parietal pleura  original coelomic cavity is reduced to slitlike space called the pleural cavity as a result of the growth of the lung.
  • 5. SUPRAPLEURAL MEMBRANE  thickening of connective tissue that covers the apex of lung  extension of endothoracic fascia that exists between parietal pleura and thoracic cage  extends between inner border of first rib and transverse process of C7 vertebra  act as a rigid barrier so as to prevent changes in intrathoracic pressure drawing upon the contents of the neck
  • 6. PARTS OF PARIETAL PLEURA  costal part  diaphragmatic part  mediastinal part  cervical pleura
  • 7. CUPOLA OR CERVICAL PART  the dome-shaped layer of parietal pleura lining the cervical extension of the pleural cavity  cervical pleura extends up into the neck, lining the undersurface of the suprapleural membrane It reaches a level 1 to 1.5 in. (2.5 to 4 cm) above the
  • 9. COSTAL PART  pleura related to the ribs and intercostal spaces
  • 10. DIAPHRAGMATIC PART  pleura covering the diaphragm
  • 11. REFLECTIONS OF PARIETAL PLEURA  Superiorly: pleural cavity can project as much as 3- 4 cm above the first costal cartilage
  • 12.  Anteriorly: pleural cavities approach each other posterior to the upper part of the sternum. posterior to the lower part of the sternum, the parietal pleura does not come as close to the midline on the left side
  • 13.  Inferiorly: In the midclavicular line, the pleural cavity extends inferiorly to rib VIII. In the midaxillary line, it extends to rib X. From this point, the inferior margin courses horizontally, to reach vertebra XII
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  • 15. VISCERAL PLEURA o Visceral pleura is continuous with parietal pleura at the hilum of each lung. o The visceral pleura is firmly attached to the surface of the lung, including both opposed surfaces of the fissures that divide the lungs into lobes.
  • 16. PULMONARY LIGAMENT  The parietal pleura surrounding the root of the lung extends downwards beyond the root as a fold called the pulmonary ligament.  The fold contains a thin layer of loose areolar tissue with a few lymphatics
  • 17.  Actually it provides a dead space into which the pulmonary veins can expand during increased venous return as in exercise.  The lung roots can also descend into it with the descent of the diaphragm
  • 18. NERVE SUPPLY OF THE PLEURA The parietal pleura is sensitive to pain, temperature, touch, and pressure  The costal pleura is segmentally supplied by the intercostal nerves.  The mediastinal pleura is supplied by the phrenic nerve.  The diaphragmatic pleura is supplied over the domes by the phrenic nerve and around the periphery by the lower six
  • 19.
  • 20. NERVE SUPPLY OF VISCERAL PLEURA  The visceral pleura covering the lungs is sensitive to stretch but is insensitive to common sensations such as pain and touch.  It receives an autonomic nerve supply from the pulmonary plexus
  • 21. BLOOD SUPPLY  The parietal pleura is supplied by intercostal, internal thoracic and musculophrenic arteries.  The veins drain mostly into the azygos and internal thoracic veins.  The pulmonary pleura, like the lung, is supplied by the bronchial arteries
  • 22. LYMPHATIC DRAINAGE  PARIETAL PLEURA: The lymphatics drain into the intercostal, internal mammary, posterior mediastinal and diaphragmatic nodes.  VISCERAL PLEURA: It is drained by the bronchopulmonary lymph nodes.
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  • 24. PLEURAL CAVITY  Two pleural cavities are situated on either side of the mediastinum  During development, the lungs grow out of the mediastinum, becoming surrounded by the pleural cavities. As a result, the outer surface of each organ is covered by pleura
  • 25.  Each lung remains attached to the mediastinum by a root formed by the airway, pulmonary blood vessels, lymphatic tissues, and nerves  Only a potential space normally exists between the visceral pleura covering lung and the parietal pleura lining the wall of the thoracic cavity
  • 26.  Two pleural cavities, one on either side of the mediastinum, surround the lungs  superiorly: extend above rib I into the root of the neck  inferiorly: they extend to a level just above the costal margin  medialy: wall of each pleural cavity is the mediastinum
  • 27. PLEURAL RECESSES  The lungs do not completely fill the anterior or posterior inferior regions of the pleural cavities  This results in recesses in which two layers of parietal pleura become opposed.  Expansion of the lungs into these spaces usually occurs only during forced inspiration  the recesses provide potential spaces in which fluids can collect and from which fluids can be aspirated
  • 28.  Costomediastinal recesses: Anteriorly, where costal pleura is opposed to mediastinal pleura. The largest is on the left side in the region overlying the heart.
  • 29. COSTODIAPHRAGMATIC RECESS  The largest and clinically most important recesses  occur in each pleural cavity between the costal pleura and diaphragmatic pleura
  • 30.  The costodiaphragmatic recesses are the regions between the inferior margin of the lungs and inferior margin of the pleural cavities  They are deepest after forced expiration and shallowest after forced inspiration
  • 31. PLEURAL FLUID  The pleural space normally contains 5 to 10 mL of clear fluid, which lubricates the apposing surfaces of the visceral and parietal pleura during respiratory movements  The formation of the fluid results from hydrostatic and osmotic pressures
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  • 33.  Since the hydrostatic pressures are greater in the capillaries of the parietal pleura than in the capillaries of the visceral pleura (pulmonary circulation), the pleural fluid is normally absorbed into the capillaries of the visceral pleura.
  • 34.  Any condition that increases the production of the fluid (e.g., inflammation, malignancy, congestive heart disease) or impairs the drainage of the fluid (e.g., collapsed lung) results in the abnormal accumulation of fluid, called pleural effusion  The presence of 300 mL of fluid in the costodiaphragmatic recess in an adult is sufficient to enable its clinical detection  The clinical signs include decreased lung expansion on the side of the effusion, with decreased breath sounds and dullness on
  • 35.  A collection of pus in the pleural cavity is called an empyema  Aspiration of any fluid from the pleural cavity is called paracentesis thoracis.  It is usually done in the 8th intercostal space in the midaxillary line. The needle is passed through the lower part of the space to avoid injury to the principal neurovascular bundle.
  • 36. PLEURISY  Inflammation of the pleura (pleuritis or pleurisy), secondary to inflammation of the lung, results in the pleural surfaces becoming coated with inflammatory exudate, causing the surfaces to be roughened.  This roughening produces friction, and a pleural rub can be heard with the stethoscope on inspiration and expiration.  exudate becomes invaded by fibroblasts, which lay down collagen and bind the visceral pleura to the parietal pleura, forming pleural adhesions
  • 37. PNEUMOTHORAX  As the result of disease or injury, air can enter the pleural cavity from the lungs or through the chest wall  Stab wounds of the thoracic wall may pierce the parietal pleura so that the pleural cavity is open to the outside air  This condition is called open
  • 38. PNEUMOTHORAX  In these circumstances, the air pressure builds up on the wounded side and pushes the mediastinum toward the opposite side  In this situation, a collapsed lung is on the injured side and the opposite lung is compressed by the deflected mediastinum. This dangerous condition is called a tension pneumothorax
  • 39.  Air in the pleural cavity associated with serous fluid is known as hydropneumothorax, associated with pus as pyopneumothorax, and associated with blood as hemopneumothorax
  • 40.  In hemopneumothorax, blood enters the pleural cavity. It can be caused by stab or bullet wounds to the chest wall, resulting in bleeding from blood vessels in the chest wall, from vessels in the chest cavity, or from a lacerated lung
  • 41.