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The authors have no financial interestThe authors have no financial interest
Blanco Torcal B; Sánchez-Pina, JMª; Lorente Hevia P;
Villar Arrondo E; Carrillo Ramos V; García-Pérez J;
Álvarez-Rementería Capelo L.
INTRODUCTION
 Ultrasound pachymetry (US) is the gold standard to
measure central corneal thickness (CCT)
 limitations : 1-3
 Reproducibility ,
 Contact instrument ,
 Mild patient discomfort, …
 Studies comparing CCT between US and noncontact devices : 4-10
 low-coherence reflectometry
 optical coherence tomography (OCT)
 scanning-slit topography/ pachymetry
 noncontact specular microscope
 rotating Scheimpflug camera.(Pentacam, Galilei, Sirius)…
1.Gordon A, Boggess EA, Molinari JF (1990) Variability of ultrasonic pachometry. Optom Vis Sci; 67:162-165.
2.Miglior S, Albe E, Guareschi M, et al. Intraobserver and interobserver reproducibility in the evaluation of ultrasonic pachymetry measurements of central corneal thickness. Br J Ophthalmol 2004; 88:174–177
3.Marsich MM, Bullimore MA. The repeatability of corneal thickness measures. Cornea 2000; 19:792–795
4.Barkana Y, Gerber Y, Elbaz U, Schwartz S, Ken-Dror G, Avni I, Zadok D (2006) Central corneal thickness measurement with the Pentacam Scheimpflug system, optical low-coherence reflectometry pachymeter, and ultrasound pachymetry. J Cataract Refract Surg; 31:1729-1735.
5. Bechmann M, Thiel MJ, Neubauer AS, et al. Central corneal thickness measurement with a retinal optical coherence tomography device versus standard ultrasonic pachymetry. Cornea 2001; 20: 50–54
6. Chakrabarti HS, Craig JP, Brahma A, et al. Comparison of corneal thickness measurements using ultrasound and Orbscan slit-scanning topography in normal and post-LASIK eyes. J Cataract Refract Surg 2001; 27:1823–1828
7.Suzuki S, Oshika T, Oki K, Sakabe I, Iwase A, Amano S, Araie M (2003) Corneal thickness measurements: scanning-slit corneal topography and noncontact specular microscopy versus ultrasonic pachymetry. J Cataract Refract Surg; 29:1313-1318.
8. Barkana Y, et al. Central corneal thickness measurement with the Pentacam Scheimpflug system, optical low-coherence reflectometry pachymeter, and ultrasound pachymetry J Cataract Refract Surg 2005; 31:1729–1735
9. Huang J et al; Precision of a new Scheimpflug and Placido-disk analyzer in measuring corneal thickness and agreement with ultrasound pachymetry; J Cataract Refract Surg 2013; 39:219–224.
10. Faramarzi A et al; Central corneal thickness measurements after myopic photorefractive keratectomy using Scheimpflug imaging, scanning-slit topography, and ultrasonic pachymetry; J Cataract Refract Surg 2010; 36:1543–1549
But to our knowledge, this is the first study to compare OCULUS-Pentacam® CCT
measurements with the NIDEK CEM-530 Specular microscope.
PURPOSE
To compare central corneal thickness in cataratous
adult eyes measured with OCULUS-Pentacam® and with
the NIDEK CEM-530 Specular microscope.
METHODS
 Prospective, observational and cross-sectional study.
 CCT was measured in 84 right eyes of 84 consecutive patients .
 All CCT measurements were performed by the same examiner, using a:
 Rotating Scheimpflug camera topographer (OCULUS-Pentacam®) before and after cataract
surgery
 NIDEK CEM-530 (specular microscope) previous to the surgery
 All measurements were made between 4 and 7 p.m. to avoid diurnal variations of CCT.
 The mean of 3 measurements was calculated for each case with the 3 devices.
Specular
before Surgery
Pentacam
before Surgery
Pentacam
After Surgery
CCT (μm) 554.72 ± 29.82 546.09 ± 27.44 546.44 ± 29.33
RESULTS
• The Paired Student's t-test only show a statistically significant difference (p<0.05)
comparing the pachymetry before cataract surgery with the two devices.
CONCLUSION
 NO difference in CCT measurements in adult eyes before and after cataract
extraction with Pentacam®
 can suggest that the lens opacity does not affect the pachymetry
 can also suggest that cataract surgery performed without problems does not change
the corneal thickness.
 There was a statiscally significative difference in CCT between OCULUS-
Pentacam® and NIDEK CEM-530 in eyes before cataract surgery, but is not
clinically relevant.
 The OCULUS-Pentacam® Rotating Scheimpflug camera topographer and
NIDEK CEM-530 specular microscope seems to be 2 interchangeable non-
contact devices to measure CCT.
CONCLUSION
 NO difference in CCT measurements in adult eyes before and after cataract
extraction with Pentacam®
 can suggest that the lens opacity does not affect the pachymetry
 can also suggest that cataract surgery performed without problems does not change
the corneal thickness.
 There was a statiscally significative difference in CCT between OCULUS-
Pentacam® and NIDEK CEM-530 in eyes before cataract surgery, but is not
clinically relevant.
 The OCULUS-Pentacam® Rotating Scheimpflug camera topographer and
NIDEK CEM-530 specular microscope seems to be 2 interchangeable non-
contact devices to measure CCT.

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EVALUATION OF CORNEAL THICKNESS USING TWO DIFFERENT NON-CONTACT DEVICES IN ADULT EYES.

  • 1. The authors have no financial interestThe authors have no financial interest Blanco Torcal B; Sánchez-Pina, JMª; Lorente Hevia P; Villar Arrondo E; Carrillo Ramos V; García-Pérez J; Álvarez-Rementería Capelo L.
  • 2. INTRODUCTION  Ultrasound pachymetry (US) is the gold standard to measure central corneal thickness (CCT)  limitations : 1-3  Reproducibility ,  Contact instrument ,  Mild patient discomfort, …  Studies comparing CCT between US and noncontact devices : 4-10  low-coherence reflectometry  optical coherence tomography (OCT)  scanning-slit topography/ pachymetry  noncontact specular microscope  rotating Scheimpflug camera.(Pentacam, Galilei, Sirius)… 1.Gordon A, Boggess EA, Molinari JF (1990) Variability of ultrasonic pachometry. Optom Vis Sci; 67:162-165. 2.Miglior S, Albe E, Guareschi M, et al. Intraobserver and interobserver reproducibility in the evaluation of ultrasonic pachymetry measurements of central corneal thickness. Br J Ophthalmol 2004; 88:174–177 3.Marsich MM, Bullimore MA. The repeatability of corneal thickness measures. Cornea 2000; 19:792–795 4.Barkana Y, Gerber Y, Elbaz U, Schwartz S, Ken-Dror G, Avni I, Zadok D (2006) Central corneal thickness measurement with the Pentacam Scheimpflug system, optical low-coherence reflectometry pachymeter, and ultrasound pachymetry. J Cataract Refract Surg; 31:1729-1735. 5. Bechmann M, Thiel MJ, Neubauer AS, et al. Central corneal thickness measurement with a retinal optical coherence tomography device versus standard ultrasonic pachymetry. Cornea 2001; 20: 50–54 6. Chakrabarti HS, Craig JP, Brahma A, et al. Comparison of corneal thickness measurements using ultrasound and Orbscan slit-scanning topography in normal and post-LASIK eyes. J Cataract Refract Surg 2001; 27:1823–1828 7.Suzuki S, Oshika T, Oki K, Sakabe I, Iwase A, Amano S, Araie M (2003) Corneal thickness measurements: scanning-slit corneal topography and noncontact specular microscopy versus ultrasonic pachymetry. J Cataract Refract Surg; 29:1313-1318. 8. Barkana Y, et al. Central corneal thickness measurement with the Pentacam Scheimpflug system, optical low-coherence reflectometry pachymeter, and ultrasound pachymetry J Cataract Refract Surg 2005; 31:1729–1735 9. Huang J et al; Precision of a new Scheimpflug and Placido-disk analyzer in measuring corneal thickness and agreement with ultrasound pachymetry; J Cataract Refract Surg 2013; 39:219–224. 10. Faramarzi A et al; Central corneal thickness measurements after myopic photorefractive keratectomy using Scheimpflug imaging, scanning-slit topography, and ultrasonic pachymetry; J Cataract Refract Surg 2010; 36:1543–1549 But to our knowledge, this is the first study to compare OCULUS-Pentacam® CCT measurements with the NIDEK CEM-530 Specular microscope.
  • 3. PURPOSE To compare central corneal thickness in cataratous adult eyes measured with OCULUS-Pentacam® and with the NIDEK CEM-530 Specular microscope.
  • 4. METHODS  Prospective, observational and cross-sectional study.  CCT was measured in 84 right eyes of 84 consecutive patients .  All CCT measurements were performed by the same examiner, using a:  Rotating Scheimpflug camera topographer (OCULUS-Pentacam®) before and after cataract surgery  NIDEK CEM-530 (specular microscope) previous to the surgery  All measurements were made between 4 and 7 p.m. to avoid diurnal variations of CCT.  The mean of 3 measurements was calculated for each case with the 3 devices.
  • 5. Specular before Surgery Pentacam before Surgery Pentacam After Surgery CCT (μm) 554.72 ± 29.82 546.09 ± 27.44 546.44 ± 29.33 RESULTS • The Paired Student's t-test only show a statistically significant difference (p<0.05) comparing the pachymetry before cataract surgery with the two devices.
  • 6. CONCLUSION  NO difference in CCT measurements in adult eyes before and after cataract extraction with Pentacam®  can suggest that the lens opacity does not affect the pachymetry  can also suggest that cataract surgery performed without problems does not change the corneal thickness.  There was a statiscally significative difference in CCT between OCULUS- Pentacam® and NIDEK CEM-530 in eyes before cataract surgery, but is not clinically relevant.  The OCULUS-Pentacam® Rotating Scheimpflug camera topographer and NIDEK CEM-530 specular microscope seems to be 2 interchangeable non- contact devices to measure CCT.
  • 7. CONCLUSION  NO difference in CCT measurements in adult eyes before and after cataract extraction with Pentacam®  can suggest that the lens opacity does not affect the pachymetry  can also suggest that cataract surgery performed without problems does not change the corneal thickness.  There was a statiscally significative difference in CCT between OCULUS- Pentacam® and NIDEK CEM-530 in eyes before cataract surgery, but is not clinically relevant.  The OCULUS-Pentacam® Rotating Scheimpflug camera topographer and NIDEK CEM-530 specular microscope seems to be 2 interchangeable non- contact devices to measure CCT.