2. Objectives
• What is Meckel’s
• Symptoms of
Meckel’s
• Diagnosing Meckel’s
• Treatment of
Meckle’s
3. What is Meckel’s
Meckel's diverticulum is a small bulge in the small
intestine present at birth
t is a vestigial remnant of the omphalomesenteric
duct, and is the most frequent malformation of the
gastrointestinal tract
t is present in approximately 2% of the population,
found twice as frequently in males as females,
although males more frequently experience
symptoms
t is named after Johann Friedrich Meckel, who first
4. What is Meckel’s
t can usually be found within about 60-100 cm of
the ileocecal valve. It is typically 3-5 cm long,
runs antimesenterically and has its own blood
supply
an be present in an indirect hernia, where it is
known as Hernia of Littre. Furthermore, it can be
attached to the umbilicus, with the possibility of
local cysts, torsions of intestine around the
intestinal stalk, leading to obstruction, ischemia,
and necrosis
5. Symptoms of Meckel’s
pproximately 98% of people afflicted with Meckel's diverticulum
are asymptomatic. If symptoms do occur, they typically appear
before the age of two.
he most common presenting symptom is painless rectal
bleeding, followed by intestinal obstruction, volvulus and
intussusception.
ccasionally, Meckel's diverticulitis may present with all the
features of acute appendicitis. Also, severe pain in the upper
abdomen is experienced by the patient along with bloating of the
stomach region.
6. Diagnosing Meckel’s
erfrom Meckel’s Scan
– Iindications:
• Detection and localization of a Meckels diverticulum
containing functioning (bleeding) gastric mucosa.
• Detection of Barrett's esophagus
7. Diagnosing Meckel’s
ATIENT PREPARATION:
atient's G.I. tract should be barium free.
Optional) Administer cimetidine prior to injecting the
radiopharmaceutical:
ive 300 mg intravenously 30 minutes prior to the study. (Dilute to
20 mL and infuse over 5 minutes. or
ive 300 mg orally 60 minutes prior to the study.)
c-99m-sodium pertechnetate is given by standard intravenous
8. Diagnosing Meckel’s
THER CONSIDERATIONS/RATIONALE:
– The radiopharmaceutical is actively secreted by
gastric mucosa. Although all Meckel's diverticula do
not contain functioning gastric mucosa, most that
bleed do
– Patient's with active hemorrhage can also be studied
with tagged red blood cells. While only 20% of
Meckel's Diverticula contain ectopic mucosa, greater
than 90% of diverticula that bleed do.