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Case studies in Lymphomas
Dr.CSBR.Prasad, MD.,
March-2017-CSBRP
Case-1
• 52yo, F. complains of painless enlarging lumps in both axilla for the
past 3months
• She has weakness and dry cough since one month
• Chest radiograph reveled 1cm mass with irregular margins in the
right lower lung lobe
• CT failed to show any cavitation / calcification in the mass
• There is no hilar / mediastinal lymphadenopathy
• Local examination: Right axilla – matted lymphnodes meauring 5cm
in diameter. Left axilla – 4 discreet firm lymphnodes. There are two
discreet lymphnodes in the left upper cervical region
• There is no organomegaly
• CBC was normal
• ESR 80mm at the end of 1st hour
• FNAC of lung nodule was performed
March-2017-CSBRP
AP view
March-2017-CSBRP
Lateral view
March-2017-CSBRP
FNAC smear from lung lesion
March-2017-CSBRP
FNAC smear from right axillary lesion
March-2017-CSBRP
Excised axillary lymph node
March-2017-CSBRP
Excised axillary lymphnode
March-2017-CSBRP
Excised axillary lymphnode
March-2017-CSBRP
• What are your findings in the x-ray chest
• Describe the cytology smears
• Describe the gross appearance of lymphjnode
• What are the findings in histology of
lymphnode?
• What is your diagnosis?
March-2017-CSBRP
• What is the stage?
March-2017-CSBRP
Case-2
• 40yo, F. presented with h/o gastritis since
many years
• Recently she started to have persistent pain
abdomen
• Upper GI Endoscopy is given in the next image
• A gastric biopsy was done
March-2017-CSBRP
Endoscopic view of different regions of
stomach
March-2017-CSBRP
Low power
view of
gastric biopsy
March-2017-CSBRP
Closer view of gastric biopsy
March-2017-CSBRP
Case-2
• Describe the endoscopic findings ?
• What is shown in the gastric biopsy?
• What further test you want to do?
• If it is single lesion what is the usual mode of
treatment?
March-2017-CSBRP
Case-3
• 5yo, African girl
with rapidly
growing jaw
swelling of
2months duration
March-2017-CSBRP
Plain x-ray
MRI
March-2017-CSBRP
FNAC smear
March-2017-CSBRP
Biopsy from jaw lesion
March-2017-CSBRP
• Describe the clinical image
• What do your think of x-ray findings? Is it
malignant or benign?
• Describe the FNAC smear
• What are your findings in biopsy?
• What further test your do confirm your
diagnosis?
March-2017-CSBRP
Case-4
• 70yo, M. was evaluated for weakness
• o/e Patient had generalized non tender
lymphadenopathy
• CBC was done
March-2017-CSBRP
CBC report
March-2017-CSBRP
Peripheral Blood smear
March-2017-CSBRP
Lymphnode biopsy
March-2017-CSBRP
Bone marrow biopsy
March-2017-CSBRP
• What are abnormal findings in the CBC
report?
• Describe the peripheral blood smear?
• Describe the lymphnode biopsy. What those
arrows pointing to?
• What are your findings in BM biopsy?
• What is the nature of this lesion?
March-2017-CSBRP
Case-5 Can this be Hodgkin’s
Lymphoma?
CSBRP-March-2017
Case-6 Give your findings and DDs
CSBRP-March-2017
Case-7
Nuclear imaging
What is your most
probable diagnosis?
Based on what
findings?
CSBRP-March-2017
March-2017-CSBRP

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Case stuies in Lymphomas