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Brain Simulator
- 1. Project – Brain Simulator May 1st, 2010 Speaker : Tony Tseng Advisor : Hsing Mei Web Computing Laboratory Computer Science and Information Engineering Department Fu Jen Catholic University
- 2. Outline Introduction Brain Network The Theory of Neuronal Group Selection Case Study - Alzheimer's disease Ideas of Brain Simulator Conclusion and Future Work 2 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net
- 3. Introduction Web Intelligence Understand Human Intelligence Brain Informatics Simulate Brain Models for new Web Intelligence Step One Brain Simulator 3 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net
- 4. Brain Network Thalamo-cortical motif Polysynaptic loop structure Diffuse ascending projections 4 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net
- 5. Thalamo-cortical motif Thalamocortical radiations Directions Thalamus – Cortex Cortex – Cortex Cortex – Thalamus Reentrant mapping Small World Network 5 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net from Edelman & Tononi, 2000
- 6. Diffuse ascending projections Value System Neurotransmitters 6 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net from Edelman & Tononi, 2000
- 7. The Theory of Neuronal Group Selection Developmental Selection The formation during brain development Neurons fire together wire together 7 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net from Edelman & Tononi, 2000
- 8. The Theory of Neuronal Group Selection Experiential Selection Synaptic selection Refining brain maps into internal representations 8 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net from Edelman & Tononi, 2000
- 9. The Theory of Neuronal Group Selection Reentrant Mapping This is the process of neuronal integration The thalamo-cortical system 9 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net from Edelman & Tononi, 2000
- 10. Case Study - Alzheimer's disease The most common form of dementia Affect 1 in 85 people globally by 2050 Causes Tangles Plaques The neurotransmitter acetylcholine 10 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net from AHAF
- 11. Case Study - Alzheimer's disease Comparison of a normal aged brain (left) and an Alzheimer's patient's brain (right) 11 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net from wikipedia
- 12. Case Study - Alzheimer's disease The acetylcholine pathway 12 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net from thebrain
- 13. Ideas of Brain Simulator 13 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net
- 14. Ideas of Brain Simulator Macro (Global) Dynamic Core Spatial Temporal Integration of Brian Maps Mesco (Intermediate) Neural Migration Degeneracy Micro (Local) Neurogenesis Synaptogenesis / Synaptic Prunning Myelination 14 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net
- 15. Ideas of Brain Simulator Analysis of Brain Simulator Simulate Brain Models for new Web Intelligence 15 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net
- 16. Conclusion and Future Work Brain Network TNGS Ideas of Brain Simulator Future Work Polysynaptic loop structure Results of AD related experiments Modeling our brain simulator Brain-Oriented SLS 16 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net
- 17. 17 ~END~ THANK YOU 08:29 WECO Lab, CSIE Dept., FJU http://www.weco.net