CBN may be the fountain of youth, read this https://cannabis.net/blog/medical/is-cbn-the-fountain-of-youth-cbn-helps-protect-brain-cells-from-the-aging-process-says-new-medi

1. 2/7/22, 4:13 PM Is CBN the Fountain of Youth? - CBN Helps Protect Brain Cells from the Aging Process Says New Medical Study
https://cannabis.net/blog/medical/is-cbn-the-fountain-of-youth-cbn-helps-protect-brain-cells-from-the-aging-process-says-new-medi 2/10
CBN FOUNTAIN OF YOUTH ANTI-AGING
Is CBN the Fountain of Youth? - CBN Helps
Protect Brain Cells from the Aging Process
Says New Medical Study
Can the cannabinoid CBN help slow aging in brain cells and protect the brain from age-related
conditions?
Posted by:
Joseph Billions , today at 12:00am
 Edit Article (https://cannabis.net/mycannabis/c-blog-entry/update/is-cbn-the-fountain-of-youth-cbn-helps-protect-brain-cells-from-the-aging-process-says-new-medi)
 Article List (https://cannabis.net/mycannabis/c-blog)

2. 2/7/22, 4:13 PM Is CBN the Fountain of Youth? - CBN Helps Protect Brain Cells from the Aging Process Says New Medical Study
https://cannabis.net/blog/medical/is-cbn-the-fountain-of-youth-cbn-helps-protect-brain-cells-from-the-aging-process-says-new-medi 3/10
It turns out that one of the ways your brain cells can remain sharp over time is with a steady dose of CBD. Some days
back, the brilliant scientists at Salk revealed this fantastic discovery. They said that CBN, a minor and relatively
unknown cannabinoid, has the potential to protect brain cells from the adverse impact of aging.
Research on medical cannabis has been going on for many decades. For the most of this duration, scientists have
focused more on the therapeutic properties of major cannabinoid compounds, i.e., THC and CBD. Minor cannabinoids
like cannabinol (CBN), cannabidiolic acid (CBDA), cannabigerolic acid (CBGA), acid (CBNA), cannabidivarin (CBDV),
tetrahydrocannabivarin (THCV), cannabigerol (CBG), and acid (THCA) have been given less attention. We've begun to
observe an influx of research into these minor compounds.
Scientists say that these minor cannabinoids have more to offer medically. New researchers are investigating how
these compounds are broken down and their interactions with the endocannabinoid system, emphasizing their effects
on the brain.
Cannabinol and the Human Brain
Cannabinol has a similar molecular structure to THC, the major difference being that it is not psychoactive. The non-
psychoactive property of the compound has caused it to be less regulated by federal agencies. The Salk researchers
were pleased to announce their latest influential studies, which have established that cannabinol (CBN) positively
impacts the brain. In the last decade, scientists around the world have tried to investigate the medical potential of CBN
(https://cannabis.net/blog/medical/what-is-cannabinol-cbn). However, the federal prohibition of the cannabis plant has
limited these studies.
The primary pathway to the death of cells is through oxidative injuries. This is usually followed by neurologic disorders
in aged people. This new study describes how cannabinol can shield brain cells, also called nerve cells, from the
damaging effects of this pathway. The findings of this trial have been published in the online Free Radical Biology and
Medicine journal. The detailed report implies that cannabinol could be an effective drug to treat or manage age-
induced neurodegenerative diseases like Alzheimer's. Scientists suggest that CBN has a high potential for protecting
nerve cells as a person ages.
Salk Study Research
Professor Pamela Maher, senior author and head of Salk's Cellular Neurobiology Laboratory, said her team had
discovered the anti-neurodegenerative effects of cannabinol. She mentioned that her team studied how the
cannabinoid shields nerve cells from oxidative stress and death, which are major contributors to the onset of dementia
and Alzheimer's diseases.
According to Neuroscience News (https://neurosciencenews.com/cannabinol-brain-aging-19962/), Maher and her team
of brilliant researchers believe this discovery would lead to the development of new drugs and treatment plans to treat
various neurodegenerative diseases, particularly Alzheimer's and Parkinson's. Maher's lab had studied the use of

3. 2/7/22, 4:13 PM Is CBN the Fountain of Youth? - CBN Helps Protect Brain Cells from the Aging Process Says New Medical Study
https://cannabis.net/blog/medical/is-cbn-the-fountain-of-youth-cbn-helps-protect-brain-cells-from-the-aging-process-says-new-medi 4/10
cannabinol in the past, and this recent investigation was done to build on the first discoveries. In the preliminary
research, the team found out about the protective properties of CBN on the brain and how CBN could be used to
derive drugs for neurological diseases.
This recent study focused more on how CBN functions in the body. During this study, Salk scientists took into account
the oxytosis and ferroptosis processes, a major contributing factor to aging and diseased brain cells. The oxytosis, or
ferroptosis process occurs in aging brains. The mechanism is induced by the gradual loss of glutathione, an
antioxidant, as a person ages. It results in prominent damage or death to neural cells through lip oxidation. The trial
began by administering CBN to nerve cells to observe how they limit oxidative action. The scientists then proceeded to
propose a different mechanism to induce oxidative damage.
Observations from the Study
Following testing healthy and damaged brain cells with cannabinol, the following observations were made. The report
stated that the administered cannabinol protected the nerve cells. They also observed that the mitochondria, a cell's
powerhouse, were protected from oxidative damage.
The mitochondria in healthy cells were compared with those in damaged cells. Maher and her team found that the
mitochondria in the damaged cell appeared to be folded up in a round shape to shield it from more damage. These
scrunched-up powerhouses are frequently noticed within the brain cells of Alzheimer's and Parkinson's patients.
On the other hand, the healthy cells appropriately housed functioning mitochondria. The powerhouse in these cells
remained in its regular, non-folded form.
Maher wrote that her team successfully showed that cannabinol could contribute to maintaining mitochondria in
nerve cells. She added that the protective effects of CBN urged the proper functioning of the powerhouse.
More Information
Zhinin Liang, co-author and postdoctoral fellow, says that smoke evidence shows that cannabinol is safe for human
and animal consumption. This can be linked to the absence of psychotropic effects after CBN is consumed. The
researcher said that CBN works on specific cells (https://cannabis.net/blog/opinion/is-cbn-a-controlled-substance-yes.-
no.-maybe) in the body while delivering therapeutic effects.
Maher also noted that her team's findings reveal implications for other neurodegenerative diseases connected to
glutathione loss. The dysfunction of a nerve cell's powerhouse results in further damage to nearby tissues. The
potential of CBN to heal and maintain functions in a powerhouse suggests that it could also be used to treat other

4. 2/7/22, 4:13 PM Is CBN the Fountain of Youth? - CBN Helps Protect Brain Cells from the Aging Process Says New Medical Study
https://cannabis.net/blog/medical/is-cbn-the-fountain-of-youth-cbn-helps-protect-brain-cells-from-the-aging-process-says-new-medi 5/10
parts of the body besides the brain. This opens the floor for further research beyond the context of neurodegenerative
conditions. The next agenda item for the team is to reproduce the above study in a preclinical mouse model.
Other researchers that contributed to the success of this study include Brendan Duggan from the University of
California, Antonio Currais, David Schubert, Devin Kepchiaz, and David Soriano-Castell Salk. The Paul F. Glenn Center
for Biology of Aging Research at Salk, the Shikey Foundation, the University of California, The Bundy Foundation, and
the National Health Institute provided funding.
Bottom Line
Salk's CBN research points out the need for more investigations into lesser-studied cannabinoids. Most of these minor
cannabinoids have shown little therapeutic potential in the limited levels of research done.
Some of the therapeutic benefits possessed by CBN, as suggested by anecdotal evidence, include pain relief, stress
relief, and anti-inflammatory effects. This buttresses Maher's point that further comprehensive research must be
done.
MORE ON CBN, READ THESE...
(https://cannabis.net/blog/opinion/is-cbn-the-next-cannabis-craze-no-
offense-cbd)
IS CBN GOING TO BE BIGGER THAN CBD, READ MORE ON CBN! (https://cannabis.net/blog/opinion/is-cbn-the-next-
cannabis-craze-no-offense-cbd)
OR..
(https://cannabis.net/blog/medical/the-battle-for-a-good-nights-sleep-
is-cbn-going-to-give-melatonin-a-run-for-its-money)
IS CBN THE NEW SLEEP AID OF A YOUNGER GENERATION? (https://cannabis.net/blog/medical/the-battle-for-a-good-
nights-sleep-is-cbn-going-to-give-melatonin-a-run-for-its-money)

5. 2/7/22, 4:13 PM Is CBN the Fountain of Youth? - CBN Helps Protect Brain Cells from the Aging Process Says New Medical Study
https://cannabis.net/blog/medical/is-cbn-the-fountain-of-youth-cbn-helps-protect-brain-cells-from-the-aging-process-says-new-medi 6/10
What did you think?
Keep reading... click here
(https://cannabis.net/blog)
0 0 0 0 0 0
Leave a Comment:
Submit
What are your thoughts?
SEXY (HTTPS://CANNABIS.NET/BLOG/SEXY) SPORTS (HTTPS://CANNABIS.NET/BLOG/SPORTS)
NEWS (HTTPS://CANNABIS.NET/BLOG/NEWS) OPINION (HTTPS://CANNABIS.NET/BLOG/OPINION)
STRAINS (HTTPS://CANNABIS.NET/BLOG/STRAINS) LOCATIONS (HTTPS://CANNABIS.NET/BLOG/LOCATIONS)
VIDEOS (HTTPS://CANNABIS.NET/BLOG/VIDEOS) RECIPES (HTTPS://CANNABIS.NET/BLOG/RECIPES)
SMOKE (HTTPS://CANNABIS.NET/BLOG/SMOKE) INTERVIEW (HTTPS://CANNABIS.NET/BLOG/INTERVIEW)
B2B (HTTPS://CANNABIS.NET/BLOG/B2B) VOTE (HTTPS://CANNABIS.NET/BLOG/VOTE)
CATEGORIES

6. 2/7/22, 4:13 PM Is CBN the Fountain of Youth? - CBN Helps Protect Brain Cells from the Aging Process Says New Medical Study
https://cannabis.net/blog/medical/is-cbn-the-fountain-of-youth-cbn-helps-protect-brain-cells-from-the-aging-process-says-new-medi 7/10
TECHNOLOGY (HTTPS://CANNABIS.NET/BLOG/TECHNOLOGY) EVENTS (HTTPS://CANNABIS.NET/BLOG/EVENTS)
MEDICAL (HTTPS://CANNABIS.NET/BLOG/MEDICAL) DABS (HTTPS://CANNABIS.NET/BLOG/DABS)
HISTORY (HTTPS://CANNABIS.NET/BLOG/HISTORY) PERSONAL STORY (HTTPS://CANNABIS.NET/BLOG/PERSONAL-STORY)
FUNNY (HTTPS://CANNABIS.NET/BLOG/FUNNY) VAPING (HTTPS://CANNABIS.NET/BLOG/VAPING)
HOW TO (HTTPS://CANNABIS.NET/BLOG/HOW-TO)
(https://cannabis.net/blog/medical/cannabis-reduces-liver-disease-and-cirrhosis-risk-among-hepatitis-c-patients)
FEATURED
MEDICAL
Cannabis Reduces Liver Disease And Cirrhosis Risk Among Hepatitis C Patients
A brand-new study published in the Canadian Journal of Gastroenterology and Hepatology revealed that cannabis use is linked with a decrease in liver cirrhosis
among individuals with hepatitis C.

7. 2/7/22, 4:13 PM Is CBN the Fountain of Youth? - CBN Helps Protect Brain Cells from the Aging Process Says New Medical Study
https://cannabis.net/blog/medical/is-cbn-the-fountain-of-youth-cbn-helps-protect-brain-cells-from-the-aging-process-says-new-medi 8/10
(https://cannabis.net/blog/opinion/finally-the-death-of-the-stoner-stereotype)
OPINION
Finally, The Death Of The Stoner Stereotype!
A “stoner” is someone who smokes weed on a regular basis. The term was originally invented to discriminate against the cannabis user, attempting to
associate use with lifestyle. However, “stoners” didn’t take it as such.

8. 2/7/22, 4:13 PM Is CBN the Fountain of Youth? - CBN Helps Protect Brain Cells from the Aging Process Says New Medical Study
https://cannabis.net/blog/medical/is-cbn-the-fountain-of-youth-cbn-helps-protect-brain-cells-from-the-aging-process-says-new-medi 9/10
(https://cannabis.net/blog/opinion/10-weird-cbd-products-you-should-still-try-even-though-they-are-weird)
OPINION
10 Weird CBD Products You Should Still Try Even Though They are Weird
Cannabidiol (CBD) comes in many kinds of products, so you can try it in a form that you like. Most commonly, it’s available as oil drops, vapes, edibles, and skin
products. Some CBD manufacturers or retailers will carry different types of products, and some of them are still more rare. In fact, even if you are familiar with
CBD and the different forms they come in, you may be surprised at some of the newer and more unique products that you can find.
Home (https://cannabis.net/) Blog & News (https://cannabis.net/blog) Strains (https://cannabis.net/strains) Jobs (http://jobs.cannabis.net)
Shop (https://cannabis.net/shop) Events (https://cannabis.net/events) About Us (https://cannabis.net/about-us)
Advertising (https://cannabis.net/advertising) Affiliates (http://cannabisnet.refersion.com/) Contact Us (https://cannabis.net/contact-us)
 (https://www.facebook.com/Canabisnet/) 
(https://twitter.com/Cannabis_Net) 